Dmim013893.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila mimetica
Gene Symbol
L
Assembly
GCA_037075245.1
Location
JBAMCH010000014.1:29423673-29430432[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 4.3e-05 0.0033 17.9 3.0 1 23 150 172 150 172 0.98
2 17 0.16 12 6.7 7.3 1 23 178 200 178 200 0.97
3 17 1.7e-07 1.3e-05 25.5 3.2 1 23 206 228 206 228 0.99
4 17 1.3e-05 0.00097 19.6 0.4 1 23 234 256 234 256 0.99
5 17 0.012 0.94 10.2 0.2 2 23 334 358 333 358 0.92
6 17 0.0039 0.3 11.8 0.2 2 23 383 405 382 405 0.95
7 17 0.062 4.8 8.0 0.7 1 23 487 509 487 509 0.97
8 17 0.0036 0.27 11.9 0.1 2 23 517 538 516 538 0.91
9 17 0.00022 0.017 15.7 0.3 1 23 546 570 546 570 0.92
10 17 5 3.9e+02 2.0 0.9 2 23 606 628 605 628 0.94
11 17 0.0026 0.2 12.4 1.1 1 23 673 696 673 696 0.97
12 17 0.005 0.39 11.4 1.2 2 23 880 902 879 902 0.96
13 17 0.041 3.1 8.6 0.1 1 23 908 930 908 930 0.92
14 17 0.062 4.8 8.0 0.1 2 23 938 959 937 959 0.95
15 17 0.75 58 4.6 0.5 2 23 1059 1080 1059 1080 0.94
16 17 0.033 2.5 8.9 0.0 1 23 1090 1112 1090 1112 0.95
17 17 0.00034 0.026 15.1 1.2 1 23 1119 1141 1119 1141 0.97

Sequence Information

Coding Sequence
ATGATGGCCCTAAAGATGTTATACCGCGGTCCTAGTTCGCGTTTGGAGAATTTGATTGAAAAGATCCAGGCCACCAAGGAGATAACCAATAACGatATGTACAGTACCCACACATCGTCCAGTTATTCGCCTAGTATCTCTGACGGCACCATGACTCCCAATTCACATCACTTGCCCGGGTCTCTAGCAACCGCTGGTCAGGAGGATCATCCCACGGAGGGCAAGTTGAATGGAGGCGCCGAGGGCGGCGAGTTGCCCAAACCAAAGCGTTTGCCCCACTTCCATCACCACCATCACTATCACCATCAACAGGCTCTCAAGATAGCCAACAAGCTGCGCAAAATCAATAAGGAAGCCAAAATGGGAGCTGGTGCAGGATCCACGGGAGCAGGCTCCAAGTTTGATAAGTTGACAGGCGAGGGGATTAAAAGTCGCGGCGACGGCTCCTATCAGTGCCAGTTCTGCGAGAAGACATTTCCGCGGCTCGGCTACTTGAAGCATCACGTGCAGAGCCACGCTGAACACCTGCCTTTCAAGTGCGAGTACTGCTCCAAGCTGTTCAAGCACAAGCGATCCCGAGATCGCCATAAGAAACTGCATACCAACGAGCGGAACTACAAGTGTCCGCATTGCGAGGCAGCTTTTTCAAGGagtgatcATTTGAAGATTCACATGAAAACCCACGACATCCAGAAGCCCTTCCAGTGCAGCATGTGCAACAGGGGTTACAACACAGCCGCCGCTCTAACCTCTCACATGCAGAAGCACAAGAAGAACGCCGCCATCCTGGCAGCTGGTGGCAATCCCAATGCTTTGAACTACAGTCCACGCTCTACAGGATCTGCCTCGGCCTCGGTTTCGAGTAATGGTAGTCTGCAGAAGAGGCGTTATGCCTTGGCCCTGGCCTCGGATAGCAGTCCCAGTCGCTTGGATTTCCCCAAGAGATCGCGAAGCAGTCATGTGGGTGGCACAACCACTGCTACCCCTACGCCGCTACTGCGTTGCAGCTACTGTCCCAAGGTCACGGAGTTTAGTAGTCTGGAGCAACTGAACGCCCATCTTCAGAGTGTccacgagcagcagcagcagcagcagcaggctggGGTGAAGACTCCTGGTCAGGAGGCGGCGGAGGGCTTCCAGCTGAGCTGCGAGTACTGCACCATGAAGTTTGGCAATATTGCTGGACTCTTTCAACACATGAGAGGCACCCACATGGATAGATTGAGCAGCCCGAACTCCTACTACGAGCACTTCAATCGCCTGGCCACCGCGGGCACCTTTAGTCCACGATTGGCCATGGATTTGCCGAAGATCAAGCAGGATTTGGGAAGTCCCGAGAGGGAGACACGAGCTGCAGAGGAGGACTTGCCCACTGACTTAAGCAGCAATAAGAGGCGACCTCTGACCCCTAATCCCCAGACGCAACTGCCACCTCCTGCGGCGCCACCGGGTGTCTTCTTCTGCAATCAGTGCAACGCTGGTCTCCCAGACTTCGAGAGCTTCAGGAATCACCTGAAGAGTCACATTGCCGAGGGCATGCAGCTGGTGTGTCCCCATTGCGGTCTCAGTCTGCCTGAGCAATCGGAGTTCGAGCGCCATGTGGTGGGTCACTTCCTCATCACTGGTTCCGAGTTTAACTGCAGCTCTAGTTGTGGCAAGAGCTTTGCCAAGTCGGAGGatctgcagcagcatctgCTGGCGGAGCATGTGCTCACCCTGCTGAAGTGCTCGCTGTGCTCGGAGCTCTGCGAGAGTCGCATGGCCATGCAGCTGCACTTGGCCTGTGCGCACAGCCAGGAGACGAAGCTGCTGCGCTGCAGCGCCTGCCTGGAGCTCTTCCGCTCGGATGCGGAGTTCCATGTGCATGTGAAGACGCGTCATCAGTTGGGGGGACATCCTACGTTGGGAGGAACTTCCAATCCCCCCACCAATCCGCTGCAGTGCATGTTCTGTCGCGCCGTTTGCTCCTCGGAGCTGGAGATGCACTTCCACCTGGCTGCCCATGCACGTCAGTTTAGGTGTCCCTCCTGCCCGGAGACCTTCCACGTGGAGTTCCTGCTGGACCGGCACATGCAGAGCCAGCATGGCGGCGGCGTCAAGGACAAGGAGGCCAGCTCACCCAATATGGGCAGTCTCTATGTGAATGCCTTGCTGCCTCCTttggcggcagcggcggcggcagcagcggccacgaataacaacagcagcatTATTGACTACAATGTGGCCTTTAAGGGTTTGTttggaggagctggagcaggGGGAGCAGGATCAGGAGGTGCCACTGGAGGACCTCCTCCCTCAAGCAACAAATTCTACAGTCCTCTACAAGTAGACACCAATGCTTTGAAGGCCCAAACCTCACCACATCCTGCGCTGATGTATGGCCTAAGTCAACGCTATCTGATGGAGATGTATGCAGCCAAGTCCACTTCGCCAGCGGGAAATGAGGGAGGGGTGGCCAACCCACAAGCACCTCCGACCCAAGCAACCGCAGCACCACCACAGCCGCCAGCAAATCCACCCACTGCCACTTTTAGTTGCGGAATGTGCGAGCGACAGGACTTGCGCAGCGAGGCGGAACTTCACTCGCATCGCAAGTTGGCTCACAATCTCAAGACTGGAGTGAGTTTGCGTTGTGCCTACTGTGCGGGCAACTTTAAATCCCGCGCCGAGCTGGAGCAGCACATGAAGAGCTGCCACAATTCGACGGGCAAGCACAAGTGCTTGATATGCGACGAGGTGTTTCCCTCGCCCGCCATCCTGGCGGAGCACAAGCTGCAGCACTCGAAGGTGGGCCAGTCGGGCAAGTGCTCGCACTGTGGACAGCCGCTGGAGGATGTGGCCGCCTTCCGGGCTCACCTGGCGGAGCATGGCAGTGATGGTGCCTCCCTGCCGCTGGCCTGCATCTGCTGTCGTCAGACGCTGCACTCGGAATTCGAGCTGAGTCTGCATGCCAAGTTTCACACAAAATCCTCCTCGAGCGGTGGCAGTCTGCAGGAACCCGTGTGTGCTCTCTGCCTGGAACCCCTACCCGATGCCACCGAGGGACCCGCCAAGCTGTGCGACAAGTGCTGTCGCAAGCACAATCTGAATGGCAAGCGGAGCAAGCACTCGGAGGCACCAAATGTCCTGCCACCGCAGAGTTCTACTGCCACCTTTGTGGAGAACCGCTGTAATCTGTGCAAGATGATCCTGCCGCATGCCCAGAAGCTGCAGGAACACCTGGTGGAGCACACCTTTGCGGGCACCGAGCAGCGTGGTTTCAATTGCTACATTTGCTCCGCTGTCTTCACCGCTGCCGGTGGTCTCCTGAACCACATGGGCGAGCATGGAGCCCACTCACGGCCCTACGATTGCAGTTTGTGCCCTGAAAAGTTCTACTTCCGCGCCGAATTGGAGCATCATCAGAGGGGCCATGAGCTGAGGCCAcgtcctcctccgccgctgcCCAAGGTGGAGGTGCCCTCCTCCTCCATTCGGAACAGCAGCTCACCCAGCCAGAGTCCCGTGAGAAGTCCCACGATTGTCAAGCAGGAGCTATACGAAACGGACACCGTAGAGTCCAATGGagcagaggaggaggagccggagAATCCCCCTGAAGAAGAGGAGTACATCGAAGTGGAGCAAATAGCGCATGAGACGCGTCCCAGTGAGATGGGTTCGCAATTGGAAAGGTCCACCAGCAGCGcctaa
Protein Sequence
MMALKMLYRGPSSRLENLIEKIQATKEITNNDMYSTHTSSSYSPSISDGTMTPNSHHLPGSLATAGQEDHPTEGKLNGGAEGGELPKPKRLPHFHHHHHYHHQQALKIANKLRKINKEAKMGAGAGSTGAGSKFDKLTGEGIKSRGDGSYQCQFCEKTFPRLGYLKHHVQSHAEHLPFKCEYCSKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASASVSSNGSLQKRRYALALASDSSPSRLDFPKRSRSSHVGGTTTATPTPLLRCSYCPKVTEFSSLEQLNAHLQSVHEQQQQQQQAGVKTPGQEAAEGFQLSCEYCTMKFGNIAGLFQHMRGTHMDRLSSPNSYYEHFNRLATAGTFSPRLAMDLPKIKQDLGSPERETRAAEEDLPTDLSSNKRRPLTPNPQTQLPPPAAPPGVFFCNQCNAGLPDFESFRNHLKSHIAEGMQLVCPHCGLSLPEQSEFERHVVGHFLITGSEFNCSSSCGKSFAKSEDLQQHLLAEHVLTLLKCSLCSELCESRMAMQLHLACAHSQETKLLRCSACLELFRSDAEFHVHVKTRHQLGGHPTLGGTSNPPTNPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGGVKDKEASSPNMGSLYVNALLPPLAAAAAAAAATNNNSSIIDYNVAFKGLFGGAGAGGAGSGGATGGPPPSSNKFYSPLQVDTNALKAQTSPHPALMYGLSQRYLMEMYAAKSTSPAGNEGGVANPQAPPTQATAAPPQPPANPPTATFSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCAGNFKSRAELEQHMKSCHNSTGKHKCLICDEVFPSPAILAEHKLQHSKVGQSGKCSHCGQPLEDVAAFRAHLAEHGSDGASLPLACICCRQTLHSEFELSLHAKFHTKSSSSGGSLQEPVCALCLEPLPDATEGPAKLCDKCCRKHNLNGKRSKHSEAPNVLPPQSSTATFVENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAAGGLLNHMGEHGAHSRPYDCSLCPEKFYFRAELEHHQRGHELRPRPPPPLPKVEVPSSSIRNSSSPSQSPVRSPTIVKQELYETDTVESNGAEEEEPENPPEEEEYIEVEQIAHETRPSEMGSQLERSTSSA