Basic Information

Insect: Drosophila prostipennis
Gene Symbol: L
Assembly: GCA_037075205.1
Location: JBAMCJ010002431.1:3886501-3894061[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 4.5e-05 0.0036 17.9 3.0 1 23 152 174 152 174 0.98

2 18 0.16 13 6.7 7.3 1 23 180 202 180 202 0.97

3 18 1.8e-07 1.4e-05 25.5 3.2 1 23 208 230 208 230 0.99

4 18 1.3e-05 0.001 19.6 0.4 1 23 236 258 236 258 0.99

5 18 0.013 1 10.2 0.2 2 23 339 363 338 363 0.92

6 18 0.0016 0.13 13.1 0.4 2 23 383 405 382 405 0.96

7 18 0.065 5.1 8.0 0.7 1 23 489 511 489 511 0.97

8 18 0.0037 0.29 11.9 0.1 2 23 519 540 518 540 0.91

9 18 0.00035 0.027 15.2 0.2 1 23 548 572 548 572 0.92

10 18 1.9 1.5e+02 3.4 0.2 2 20 578 596 577 597 0.93

11 18 5.3 4.1e+02 2.0 0.9 2 23 608 630 607 630 0.94

12 18 0.0027 0.21 12.4 1.1 1 23 675 698 675 698 0.97

13 18 0.0053 0.41 11.4 1.2 2 23 885 907 884 907 0.96

14 18 0.043 3.3 8.6 0.1 1 23 913 935 913 935 0.92

15 18 0.051 4 8.3 0.1 2 23 943 964 942 964 0.96

16 18 0.78 61 4.6 0.5 2 23 1062 1083 1062 1083 0.94

17 18 0.021 1.6 9.5 0.0 1 23 1093 1115 1093 1115 0.95

18 18 0.00036 0.028 15.1 1.2 1 23 1122 1144 1122 1144 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	4.5e-05	0.0036	17.9	3.0	1	23	152	174	152	174	0.98
2	18	0.16	13	6.7	7.3	1	23	180	202	180	202	0.97
3	18	1.8e-07	1.4e-05	25.5	3.2	1	23	208	230	208	230	0.99
4	18	1.3e-05	0.001	19.6	0.4	1	23	236	258	236	258	0.99
5	18	0.013	1	10.2	0.2	2	23	339	363	338	363	0.92
6	18	0.0016	0.13	13.1	0.4	2	23	383	405	382	405	0.96
7	18	0.065	5.1	8.0	0.7	1	23	489	511	489	511	0.97
8	18	0.0037	0.29	11.9	0.1	2	23	519	540	518	540	0.91
9	18	0.00035	0.027	15.2	0.2	1	23	548	572	548	572	0.92
10	18	1.9	1.5e+02	3.4	0.2	2	20	578	596	577	597	0.93
11	18	5.3	4.1e+02	2.0	0.9	2	23	608	630	607	630	0.94
12	18	0.0027	0.21	12.4	1.1	1	23	675	698	675	698	0.97
13	18	0.0053	0.41	11.4	1.2	2	23	885	907	884	907	0.96
14	18	0.043	3.3	8.6	0.1	1	23	913	935	913	935	0.92
15	18	0.051	4	8.3	0.1	2	23	943	964	942	964	0.96
16	18	0.78	61	4.6	0.5	2	23	1062	1083	1062	1083	0.94
17	18	0.021	1.6	9.5	0.0	1	23	1093	1115	1093	1115	0.95
18	18	0.00036	0.028	15.1	1.2	1	23	1122	1144	1122	1144	0.97

Sequence Information

Coding Sequence: ATGATGGCCCTAAAGATGTTATATCGCGGTCCCAGTTCGCGTTTGgagaatttaattgaaaagatCCAGGCCACCAAGGAGATAACCAATAACGATATGTACAGTACCCACACATCGTCCAGTTATTCGCCTAGTATTTCTGACGGCACCATGACTCCCAATTCACACCACTTGCCTGGAGCTCTAGCAACCGCGGGTCAGGAGGATCACCCCACTGAGGGCAAGGTCAACGGTGGAGCTGAAGGCGGGGAGTTGCCCAAGCCAAAGCGAATGCCCCACTtccatcaccatcaccactATCACCATCAACAGGCGCTGAAGATAGCCAACAAGCTGCGCAAAATCAATAAGGAAGCCAAAATGGGAGCTAGCGCCGGTGCAGGATCCACTGGAGCAGTCTCCAAGTTTGATAAGTTGACAGGCGAGGGGATTAAAAGTCGCGGCGACGGCTCCTATCAGTGCCAGTTCTGCGAGAAGACATTTCCGCGGCTCGGCTACTTGAAGCATCACGTACAGAGCCACGCTGAACACCTGCCTTTCAAATGCGAATACTGCTCCAAGCTGTTCAAGCACAAGCGATCCCGAGATCGTCATAAGAAGTTGCATACCAACGAGCGGAACTACAAGTGTCCGCATTGCGAGGCAGCTTTTTCCAGAAGTGACCACTTGAAGATCCACATGAAGACCCATGACATCCAGAAGCCCTTCCAGTGCAGCATGTGCAACCGGGGCTACAATACAGCCGCTGCCCTAACCTCTCATATGCAAAAGCACAAGAAGAATGCCGCCATCCTGGCAGCTGGTGGTAATCCCAATGCCCTGAACTACAGTCCACGATCCACGGGATCGGCTTCGGCATCGGTTTCAAGTAATGGTAGTCTGCAAAAGAGACGTTATGCCTTGGCTTTGGCCTCGGATAGTAGTCCCAGTCGCTTGGATTTCCCCAAGAGATCGAGAAGTAGTCATGTGGGTGGGGCAAACACCACCGCTACCGCTACGCCCACTCCTCTGCTGAGATGCAGCTACTGTCCCAAGGTCACCGAGTTCAGTAGCCTGGAGCAACTGAATGCCCATCTGCAGAGTGTCCacgagcaacagcagcagccggtGAAGACGGGAGTTCAGGAGGCGGAGGGTTTCCAGCTGAGCTGCGAGTACTGCACCATGAAGTTTGGCAACATCGCCGGTCTCTTTCAGCACATGCGAAGCACCCACATGGACCGATTGAGCAGCCCGAACTCCTATTATGAGCACTTCAATCGCCTGGCCACCGCTGGCACTTTCAGTCCGCGATTGGCCATGGATTTGCCGAAAATTAAGCAGGATTTGGGAAGCCCCGAGCGGGATTCACGACCCGCCGAGGACGATTTGCCCACGGATTTGAGCAGCAACAAGCGGCGACCACTGACACCGAATCCTCAGACCCAAACTCAGCTACCACCGCCCTCTGCGCCACCGGGGGTCTTCTTCTGCAATCAGTGCAACGCTGGACTGCCCGATTTCGAGAGCTTCAGGAATCACCTGAAGAGTCACATTGCCGAGGGCATGCAACTGGTCTGTCCGCATTGCGGTTTGAGTCTGCCGGAGCAGTCGGAGTTCGAACGTCATGTGGTGGGTCACTTCCTCATCACCGGATCCGAGTTCAACTGCAGTTCGTCGTGCGGCAAGAGCTTCGCCAAGGCGGAGGATCTGCAGCAACATTTGCTTGCGGAGCACGTCCTCACCCTGCTGAAGTGCTCCTTGTGCTCGGAAGTCTGCGAGAGTCGCATGGCCATGCAACTGCATTTGGCCTGTTCGCACAGTCAGGAGACGAAGCTCCTGCGCTGCAGCGCCTGCCTGGAGCTCTTCCGCTCCGATGCCGAGTTCCATGTGCATGTGAAGACGCGCCACCAGTTGGGCGGACatcccacgttgggcgccaatacAAATCCGCCCACCAATCCGCTGCAGTGCATGTTCTGTCGCGCCGTTTGCTCCTCGGAGCTGGAGATGCACTTCCATCTGGCGGCCCATGCGCGCCAGTTTAGATGTCCCTCCTGCCCGGAGACCTTCCATGTGGAGTTCCTGCTCGATCGTCATATGCAGAGTCAGCACGGCGGCGTCAAGGACAAGGAGGGCAGTCCACCCAGCATGGGCAGTCTCTATGTGAATGCCTTGCTACCTCCTttggcggcagcggcggcggcagcagcggccacAAATAACAACAGCAGTATCATCGACTACAATGTGGCCTTCAAGGGTTTATTCGGAGGAGCTactggaggaggagcaggttcaggaggaggagccagTGGAGGAGGACCTCCACCGGCGAGCAACAAATTCTACAGTCCCCTGCAAGTAGACACCAATGCACTGAAGGCCCAAACCTCCCCACATCCTGCCTTGATGTACGGCCTGAGTCAGCGATATCTGATGGAGATGTATGCGGCCAAGTCCACTTCGCCAGCGGGAAatgaggggggagggggaaacCCCCAGCCATCTCAGGCATCCCAGGCCAccgcagcagcaccaccaccaccgcctccAAATCCAGCGACTGCCACCTTCAGTTGCGGAATGTGCGAGCGACAGGATTTGCGCAGCGAGGCGGAACTCCACTCGCACCGCAAATTGGCCCACAACCTAAAGACGGGAGTGAGTCTGCGATGTGCCTACTGCGCGGGGAACTTCAAGTCCCGGGCGGAGTTGGAACAGCACATGAAGAGCTGTCACAATTCGACGGGCAAGCACAAGTGCTTGATATGCGACGAGGTATTTCCCTCGCCAGCCATCCTGGCCGAGCACAAGCTGCAGCACTCGAAGGTGGGGCAGTCGGGCAAGTGCTCCCACTGCGGACAGCCGCTCGAGGATGTGGCCGCCTTCAGGGCTCACCTCTCGGAACACGGCAGCGATGGTGGTTCCCTGCCACTGGCCTGCATTTGCTGTCGCCAGACGTTGCACTCGGAATTCGAGCTGAGTTTGCATGCCAAATTCCACACCAAGTCCTCCTCGAGCGGAGGGAGTCTGCAGGAACCAGTTTGTGCTTTGTGCCTGGAACCTCTGCCCGATGCCACCGAAGGACCAGCGAAGCTCTGCGACAAATGCTGTCGCAAGCACAATCTGAATGGCAAGAGGGGCAAGCTGGCGGAGCCTCCGGCAGCCCTACAACCGCCGAGTTCCGCCTTTGTGGAGAATCGCTGTAACCTCTGCAAGATGATCCTGCCACATGCCCAGAAACTGCAGGAACACCTCGTGGAACACACCTTTGCGGGCACCGAACAGCGTGGCTTCAACTGCTACATTTGCTCCGCCGTTTTCACCGCACCCGGTGGTCTGCTCAACCACATGGGCGAACATGGAGCCCATTCGCGACCCTACGATTGCAGTCTCTGCCCGGAGAAGTTCTACTTCCGCGCCGAGTTGGAGCACCACCAGCGAGGTCATGAGCTGAGGCCACGTCCTCCGCAACCCAAGGTAGAGATACCCTCCAGCCAGAGGAACAGTTCACCCAGCCAGAGTCCCACGGTGCGGAGTCCCACGATTGTCAAGCAGGAACTATACGAAACGGATACCGTGGAATCCAACGGAGCAGAGGATGAGCCAGAGAATCCGCCCGACGAGGAGGAGTACATCGAAGTGGAGCAAATGCCGCATGAGACACGTCCAAGTGAGATTGGGTCGCAATTGGAGAGGTCCACCAGTAGCGCCTAA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEITNNDMYSTHTSSSYSPSISDGTMTPNSHHLPGALATAGQEDHPTEGKVNGGAEGGELPKPKRMPHFHHHHHYHHQQALKIANKLRKINKEAKMGASAGAGSTGAVSKFDKLTGEGIKSRGDGSYQCQFCEKTFPRLGYLKHHVQSHAEHLPFKCEYCSKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASASVSSNGSLQKRRYALALASDSSPSRLDFPKRSRSSHVGGANTTATATPTPLLRCSYCPKVTEFSSLEQLNAHLQSVHEQQQQPVKTGVQEAEGFQLSCEYCTMKFGNIAGLFQHMRSTHMDRLSSPNSYYEHFNRLATAGTFSPRLAMDLPKIKQDLGSPERDSRPAEDDLPTDLSSNKRRPLTPNPQTQTQLPPPSAPPGVFFCNQCNAGLPDFESFRNHLKSHIAEGMQLVCPHCGLSLPEQSEFERHVVGHFLITGSEFNCSSSCGKSFAKAEDLQQHLLAEHVLTLLKCSLCSEVCESRMAMQLHLACSHSQETKLLRCSACLELFRSDAEFHVHVKTRHQLGGHPTLGANTNPPTNPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGVKDKEGSPPSMGSLYVNALLPPLAAAAAAAAATNNNSSIIDYNVAFKGLFGGATGGGAGSGGGASGGGPPPASNKFYSPLQVDTNALKAQTSPHPALMYGLSQRYLMEMYAAKSTSPAGNEGGGGNPQPSQASQATAAAPPPPPPNPATATFSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCAGNFKSRAELEQHMKSCHNSTGKHKCLICDEVFPSPAILAEHKLQHSKVGQSGKCSHCGQPLEDVAAFRAHLSEHGSDGGSLPLACICCRQTLHSEFELSLHAKFHTKSSSSGGSLQEPVCALCLEPLPDATEGPAKLCDKCCRKHNLNGKRGKLAEPPAALQPPSSAFVENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPGGLLNHMGEHGAHSRPYDCSLCPEKFYFRAELEHHQRGHELRPRPPQPKVEIPSSQRNSSPSQSPTVRSPTIVKQELYETDTVESNGAEDEPENPPDEEEYIEVEQMPHETRPSEIGSQLERSTSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00548267;
90% Identity: iTF_00504840;
80% Identity: -