Basic Information

Insect: Drosophila leontia
Gene Symbol: L
Assembly: GCA_008042735.1
Location: VNKB01012396.1:14167-21224[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 9e-06 0.00077 19.9 2.9 1 23 159 181 159 181 0.98

2 17 0.14 12 6.7 7.3 1 23 187 209 187 209 0.97

3 17 1.5e-07 1.3e-05 25.5 3.2 1 23 215 237 215 237 0.99

4 17 1.1e-05 0.00094 19.6 0.4 1 23 243 265 243 265 0.99

5 17 0.011 0.92 10.2 0.2 2 23 350 374 349 374 0.92

6 17 0.0013 0.11 13.0 0.4 2 23 396 418 395 418 0.96

7 17 0.055 4.7 8.0 0.7 1 23 505 527 505 527 0.97

8 17 0.0037 0.32 11.6 0.1 2 23 535 556 534 556 0.92

9 17 8.5e-05 0.0073 16.8 0.5 1 23 564 588 564 588 0.94

10 17 4.4 3.8e+02 2.0 0.9 2 23 624 646 623 646 0.94

11 17 0.0022 0.19 12.3 1.1 1 23 691 714 691 714 0.97

12 17 0.0044 0.38 11.4 1.2 2 23 904 926 903 926 0.96

13 17 0.036 3.1 8.5 0.1 1 23 932 954 932 954 0.92

14 17 0.043 3.7 8.3 0.1 2 23 962 983 961 983 0.96

15 17 0.66 56 4.6 0.5 2 23 1085 1106 1085 1106 0.94

16 17 0.0085 0.73 10.5 0.0 1 23 1116 1138 1116 1138 0.96

17 17 0.00015 0.013 16.0 1.7 1 23 1145 1167 1145 1167 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	9e-06	0.00077	19.9	2.9	1	23	159	181	159	181	0.98
2	17	0.14	12	6.7	7.3	1	23	187	209	187	209	0.97
3	17	1.5e-07	1.3e-05	25.5	3.2	1	23	215	237	215	237	0.99
4	17	1.1e-05	0.00094	19.6	0.4	1	23	243	265	243	265	0.99
5	17	0.011	0.92	10.2	0.2	2	23	350	374	349	374	0.92
6	17	0.0013	0.11	13.0	0.4	2	23	396	418	395	418	0.96
7	17	0.055	4.7	8.0	0.7	1	23	505	527	505	527	0.97
8	17	0.0037	0.32	11.6	0.1	2	23	535	556	534	556	0.92
9	17	8.5e-05	0.0073	16.8	0.5	1	23	564	588	564	588	0.94
10	17	4.4	3.8e+02	2.0	0.9	2	23	624	646	623	646	0.94
11	17	0.0022	0.19	12.3	1.1	1	23	691	714	691	714	0.97
12	17	0.0044	0.38	11.4	1.2	2	23	904	926	903	926	0.96
13	17	0.036	3.1	8.5	0.1	1	23	932	954	932	954	0.92
14	17	0.043	3.7	8.3	0.1	2	23	962	983	961	983	0.96
15	17	0.66	56	4.6	0.5	2	23	1085	1106	1085	1106	0.94
16	17	0.0085	0.73	10.5	0.0	1	23	1116	1138	1116	1138	0.96
17	17	0.00015	0.013	16.0	1.7	1	23	1145	1167	1145	1167	0.98

Sequence Information

Coding Sequence: ATGATGGCTCTAAAGATGTTATATCGCGGTCCCAGTTCGCGTTTGgagaatttaattgaaaagatCCAGGCCACCAAGGAAATAACCAATAGCGACATGTATAGTACCCACACATCGTCCAGTTACTCGCCTAGCATTTCGGATGGCACCATGACGCCGAATTCACACCATTTGCCCGGAGCTCCAACCACGGCCGGCGCCTCTAGCCAGGAAGATCATCATCATTCAAACGATGGCAAGCTCAATGGTGGCACCGATGGCGAGGAGCTGGTTAAACCAAAGCGGTTGCCACACttccatcaccatcaccatcatcattaCCACCATCAGCAGGCGCTGAAAATTGCCAACAAGCTGCGCAAAATCAATAAGGAAGCTAAAATGGGAGCTGGCGGTGGTGCTGGTTCCGGAGGAGCAGGCTCCAAGTTTGATAAGTTGACAGGCGAGGGGATTAAGGCTCGCGGCGACGGCTCCTATCAGTGTCAGTTCTGCGATAAGTCATTTCCGCGTCTCGGCTATTTGAAGCATCATGTACAGAGCCACGCCGAACACCTGCCCTTCAAGTGCGAATACTGCTCGAAGCTGTTCAAGCACAAGCGATCCCGGGATCGCCACAAGAAGCTGCATACTAACGAGCGCAACTACAAGTGTCCCCATTGCGAGGCGGCCTTCTCCAGGAGTGACCACCTGAAGATCCACATGAAGACGCACGACATCCAGAAGCCGTTCCAGTGCAGCATGTGCAACCGAGGCTATAACACGGCGGCTGCCCTAACCTCGCACATGCAGAAGCACAAGAAGAATGCGGCCATCCTGGCAGCTGGGGGCAATCCCAATGCCCTTAACTATAGTCCCCGATCCACGGGATCGGCCTCGGCCTCGGTTTCGAGTAATGGCAGTCTCCAGAAGAGGCGGTATGCCTTGGCCCTGGCCTCCGATAGTAGTCCCAGTCGCCTGGATTTTCCCAAGCGATCAAGGAGCAGTCATGTGGGTGGTGGTAATGGAGGCGGAACCACAACCACGACAGCCACACCCACTCCCCTGCTCAGGTGCAGCTACTGTCCCAAGGTCACAGAGTTTAGTAGCTTGGAGCAGCTGAATGCTCACCTGCAGAGTGTTcacgagcagcagcatcagcatgcGGCCAAGACGCCAGTAGCTCCTGAGGGCGAGAGCTTCCAACTAAGCTGCGAATATTGCACTATGAAATTCGGGAACATAGCCGGATTGTTCCAGCACATGAGGAGCACTCACCTGGACAGATTAAGCAGTCCAAACTCCTACTATGAGCACTTCAATCGCCTGGCCACAGCTGGCACTTTCAGTCCCCGCCTGGCCTTGGATTTGCCCAAAATCAAACCGGATTTGGGCAGTCCGGAGAGGGAATCCGCGCGAGCTGCCGAGGAGGATCTGCCCACCGATTTGAGCAGCAACAAGAGGCGACCCCAGACACCTAATCCACAGCAGTTGCAGTCCCAACAGCTGGCACCTCCGGCCGCTCCTCCAGGAGTATTCTTCTGCAATCAATGCAACGCTGGATTGCCGGACTTTGAGAGCTTCAGGAATCATCTGAAGAGCCACATTGCCGAGGGCATGCAGATGGTGTGTCCCCACTGCGGGTTGAGTCTGCCGGAACAGTCAGAGTTCGAGCGCCATGTGGTGGGTCACTTCCTAATCACCGGCTCAGAGTTCAACTGCAGCACCAGCTGCGGCAAGAGCTTTGCCAAGTCGGAGGATCTGCAGCAGCATCTTCTGTCCGAGCACGTCCTAACCCTGCTGAAGTGCTCGCTGTGCTCGGAACTCTGTGAGAGTAGGATGGCCATGCAGCTCCACCTGGCCTGTACACATAGCCAAGAAACGAAGCTGCTGCGCTGCAGCGCCTGCCTGGAGCTCTTCCGTTCCGACGCCGAGTTCCATGTGCACGTAAAGACGCGTCACCAACTTGGAGGACATCCCTCAATGGGTGCCACACCCAGTGCTCCTGCCAATCCGCTGCAGTGCATGTTTTGCCGGGCTGTATGCTCCTCGGAGCTGGAGATGCATTTCCATTTGGCAGCGCATGCCAGGCAGTTTAGGTGCCCGTCTTGCCCGGAAACCTTTCACGTTGAATTCCTGCTGGACAGACACATGCAGAGCCAGCATGGCGGCGGGGTCAAGGACAAGGAACAACAGCGTGGCTCCCCCAATATGGGAAGTCTCTATGTAAATGCCTTGCTGCCTCCTTTGGCAGccgcagcggcggcagcagcggccaccaataacaacagcagcatcatcgaCTACAATGTGGCTTTCAAGGGTTTgtttggaggaggagcaggcggaggagcagcatcTGGTGCAGGATCTGGTTCAGGAGGAGGCTCAGGAGCCGCCCCACCCTCGGGCAACAAGTTTTATAGTCCCTTGCAGGTGGACACCAATGCTTTGAAGGCTCAAACATCACCGCATCCCGCTCTCATGTACGGCTTGAGTCAACGCTATCTAATGGAGATGTACGCCGCCAAGTCCACATCCCCGGCGGGTGGCAACGAGGGCAATCCACAGACGCCACAGGCTCCCCAGGCCACCGCTCCGCAGCCACCGAGTGCCGCCCCAACCACTGCCACTTTTAGTTGTGGAATGTGTGAGCGCCAGGATCTGCGCAGCGAGGCTGAACTCCACTCGCACCGCAAGCTGGCCCACAACCTCAAGACGGGCGTGAGTCTAAGGTGTGCCTACTGTGCCGGGAACTTCAAGTCCAGGGCAGAGCTAGAGCAGCACATGAAGAGCTGCCACAATTCGACGGGCAAGCACAAGTGCCTGATCTGTGACGAGGTCTTCCCCTCGCCGGCCATCCTGGCCGAGCACAAGCTGCAGCACTCAAAGGTGGGCCAGTCCGGCAAGTGCTCCCACTGCGGCCAGCCACTAGAGGATGTGGCTGCCTTCAGGGCTCATCTCTCGGAGCATGGCAGCGATGGAGCCACCCTGCCGTTGGCTTGCATCTGCTGTCGCCAGACCCTGCACTCGGAGTTTGAGCTGAGCCTGCATGCCAAGTTCCACACTAAATCGGCTTCGAGCGGGGGTAGCCTCCAAGAGCCAGTGTGTGCTCTGTGCCTGGAGCCACTGCCTGATGTACTCGTCGAGGGTCCGGCCAAACTGTGCGAGAAGTGCTGTCGGAAGCACAACCTTAATGGAAAGCGGGGAAAGCCCAGTGACCCGCCGCTGCAGGCTCCCCCATCATCAGGAGGATCAGCTGCCTTTGTGGAGAACCGATGCAACCTGTGCAAGATGATCCTGCCACATGCCCAAAAGCTGCAAGAACACCTGGTGGAACACACCTTTGCCGGCACCGAGCAGCGCGGATTTAACTGCTACATCTGCTCGGCGGTGTTCACGGCCCCGGGAGGTCTACTCAATCACATGGCAGAACATGGAGCTCATTCGCGTCCCTACGACTGCAGCCTGTGTCCGGAGAAGTTCTATTTCCGGGCAGAGTTGGAGCACCATCAGAGGAGCCACGAGTTGAGGCCACAGGCAACGAGGCCAGCTATGCCCAAAGTGGAAGCACCCTCCATCAGGAATAGTTCGCCCATATGCGAGAGTCCTCCTTCCAGAAGTCGCAGTCCCACAATTAATGTCAAGCAGGAGCTCTACGAAACGGACACAGTGGAGTCGGGAGCAGGAGAAGATGAGCCAGAGGAGAACCCCCAAGAAGATGAGGAGTACATTGAAGTAGAGCAAGTGCCGCATGAGACACGTACCAGTGAGTTGGGTTCGCAAATGGAAAGGTCCACCAGCAGCGCCTAA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEITNSDMYSTHTSSSYSPSISDGTMTPNSHHLPGAPTTAGASSQEDHHHSNDGKLNGGTDGEELVKPKRLPHFHHHHHHHYHHQQALKIANKLRKINKEAKMGAGGGAGSGGAGSKFDKLTGEGIKARGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCSKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASASVSSNGSLQKRRYALALASDSSPSRLDFPKRSRSSHVGGGNGGGTTTTTATPTPLLRCSYCPKVTEFSSLEQLNAHLQSVHEQQHQHAAKTPVAPEGESFQLSCEYCTMKFGNIAGLFQHMRSTHLDRLSSPNSYYEHFNRLATAGTFSPRLALDLPKIKPDLGSPERESARAAEEDLPTDLSSNKRRPQTPNPQQLQSQQLAPPAAPPGVFFCNQCNAGLPDFESFRNHLKSHIAEGMQMVCPHCGLSLPEQSEFERHVVGHFLITGSEFNCSTSCGKSFAKSEDLQQHLLSEHVLTLLKCSLCSELCESRMAMQLHLACTHSQETKLLRCSACLELFRSDAEFHVHVKTRHQLGGHPSMGATPSAPANPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGGVKDKEQQRGSPNMGSLYVNALLPPLAAAAAAAAATNNNSSIIDYNVAFKGLFGGGAGGGAASGAGSGSGGGSGAAPPSGNKFYSPLQVDTNALKAQTSPHPALMYGLSQRYLMEMYAAKSTSPAGGNEGNPQTPQAPQATAPQPPSAAPTTATFSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCAGNFKSRAELEQHMKSCHNSTGKHKCLICDEVFPSPAILAEHKLQHSKVGQSGKCSHCGQPLEDVAAFRAHLSEHGSDGATLPLACICCRQTLHSEFELSLHAKFHTKSASSGGSLQEPVCALCLEPLPDVLVEGPAKLCEKCCRKHNLNGKRGKPSDPPLQAPPSSGGSAAFVENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPGGLLNHMAEHGAHSRPYDCSLCPEKFYFRAELEHHQRSHELRPQATRPAMPKVEAPSIRNSSPICESPPSRSRSPTINVKQELYETDTVESGAGEDEPEENPQEDEEYIEVEQVPHETRTSELGSQMERSTSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00548267;
90% Identity: iTF_00488807;
80% Identity: -