Dere008020.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila erecta
Gene Symbol
L
Assembly
GCA_000005135.1
Location
CH954179.1:15492612-15499155[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 4.4e-05 0.0031 17.9 3.0 1 23 154 176 154 176 0.98
2 17 0.16 11 6.7 7.3 1 23 182 204 182 204 0.97
3 17 1.7e-07 1.2e-05 25.5 3.2 1 23 210 232 210 232 0.99
4 17 1.3e-05 0.00089 19.6 0.4 1 23 238 260 238 260 0.99
5 17 0.012 0.86 10.2 0.2 2 23 339 363 338 363 0.92
6 17 0.004 0.28 11.8 0.2 2 23 383 405 382 405 0.95
7 17 0.063 4.4 8.0 0.7 1 23 491 513 491 513 0.97
8 17 0.0036 0.25 11.9 0.1 2 23 521 542 520 542 0.91
9 17 9.5e-05 0.0067 16.9 0.4 1 23 550 574 550 574 0.94
10 17 5.1 3.6e+02 2.0 0.9 2 23 610 632 609 632 0.94
11 17 0.0026 0.18 12.4 1.1 1 23 677 700 677 700 0.97
12 17 0.0051 0.35 11.4 1.2 2 23 884 906 883 906 0.96
13 17 0.041 2.9 8.6 0.1 1 23 912 934 912 934 0.92
14 17 0.049 3.4 8.3 0.1 2 23 942 963 941 963 0.96
15 17 0.75 53 4.6 0.5 2 23 1061 1082 1061 1082 0.94
16 17 0.02 1.4 9.5 0.0 1 23 1092 1114 1092 1114 0.95
17 17 0.00035 0.024 15.1 1.2 1 23 1121 1143 1121 1143 0.97

Sequence Information

Coding Sequence
ATGATGGCCCTAAAGATGTTGTATCGTGGTCCCAGTTCGCGTTTGgagaatttaattgaaaagatCCAGGCCACCAAGGAGATCAGCAACAACGATATGTACAGTACCCACACATCGTCCAGTTATTCGCCTAGCATTTCGGACGGCACCATGACGCCCAATTCACACCACTTGCCCGGAGCTCCAATCGCCGCCGGTCAGGAGGATCATCCAACGGAGGGCAAGATCAATGGAGGTGCTGATGGCGAGGATCTGCCGAAGCCGAAACGTTTGCCACACttccatcaccaccaccaccatcattaCCACCATCAACAGGCGCTGAAAATAGCCAACAAGCTGCGCAAAATCAATAAGGAAGCCAAAATGGGAGCCACCGCAGGTGCGGGATCCACTGGAGGAGCATCCAAGTTTGATAAGTTGACAGGAGAGGGGATTAAAAGTCGCGGCGACGGCTCCTACCAGTGCCAGTTCTGCGAAAAGACATTTCCGCGTCTCGGCTACTTGAAGCATCACGTGCAGAGCCACGCCGAACACCTGCCCTTTAAATGCGAATACTGCTCCAAGCTCTTCAAGCACAAGCGTTCCCGAGATCGCCACAAGAAACTGCACACCAACGAGCGGAACTACAAGTGTCCGCATTGCGAGGCAGCCTTTTCCAGGAGTGACCACTTGAAGATCCACATGAAGACCCATGACATTCAGAAGCCCTTCCAGTGCAGCATGTGCAACAGGGGCTACAATACAGCTGCGGCACTAACCTCCCACATGCAGAAGCACAAGAAGAATGCTGCCATCCTGGCCGCCGGTGGCAATCCGAATGCCCTCAACTACAGTCCAAGGTCCACGGGATCTGCCTCGGCATCGGTGTCCAGCAATGGTAGTCTGCAGAAGAGGAGGTATGCCTTGGCTCTGGCATCAGACAGCAGTCCCAGTAGACTGGACTTCCCCAAGAGGTCGCGGAGTAATCATGTGGGAGGCACTACCACCACCGCCACACCCACTCCTCTGCTCAGATGCAGCTACTGCCCCAAGGTCACGGAGTTCAGCAGCCTGGAGCAACTCAATGCCCATCTGCAGAGTGTCCACGAACAACCGCAGCAGGCTGTGAAGACGCCGGTGCAGGAGGGCGAAGGCTTCCAGCTGAGCTGTGAGTACTGCACCATGAAGTTTGGCAATATCGCCGGACTTTTTCAGCACATGCGGGGCACTCACATGGACCGATTGAGTAGTCCAAACTCCTACTACGAGCACTTCAATCGCCTGGCCACCGCTGGCACTTTCAGTCCCCGCCTGGCCCTGGACTTGCCCAAAATTAAGCCGGACTTGGGCAGTCCGGAGCGGGAGTCGCGACCCGCAGAGGACGATCTGCCCACAGACTTGAGCAGCAACAAGCGGCGACCATTGACACCCAATccccaagcccaagcccagGCTCCACTGGCTCCACCCACTGCCCCACCGGGCGTATTCTTCTGCAATCAGTGCAACGCTGGACTGCCGGACTTCGAGAGCTTTAGGAACCATCTGAAGAGTCACATTGCCGAGGGCATGCAGCTGGTTTGTCCGCACTGCGGACTGAGTTTGCCGGAGCAATCGGAGTTCGAGCGCCATGTGGTGGGACACTTTCTCATCACGGGCTCAGAGTTCAACTGCAGCTCGAGCTGCGGCAAGAGTTTCGCCAAATCGGAGGATCTGCAGCAACATTTGCTGTCGGAGCACGTCCTAACGCTGCTGAAGTGCTCGTTGTGCTCGGAGCTCTGTGAAAGCCGCATGGCCATGCAGCTGCATCTGGCCTGTGCCCACAGCCAGGAAACCAAGCTGCTCCGCTGCAGCGCCTGTCTGGAGCTCTTTCGCTCCGACGCCGAGTTCCATGTGCATGTGAAGACGCGTCACCAGTTGGGCGGCCatcccacgttgggcgccacttCCAATGCACCCACTAATCCGCTGCAGTGCATGTTCTGCCGCGCAGTTTGCTCTTCCGAGCTGGAAATGCACTTCCACTTGGCCGCACATGCACGTCAGTTCAGATGTCCTTCCTGCCCGGAGACCTTCCACGTGGAGTTTCTGCTGGATCGCCACATGCAGAGTCAGCATGGTGGCGTCAAGGAGAAGGAGGCCAACTCGCCCAACATGGGCAGTCTGTATGTGAATGCCTTGCTGCCTCCTttggcggcagcggcggcggcagcagcggccacaaacaacaacagcagcatcatcgACTACAATGTGGCATTTAAGGGTTTGTTCGGAGGAGCTGCCGGCGCAGCCGGAtcaggaggcggaggcggaggaggagcacaAGCTGGTGGTGCACCGCCTTCGGCCAACAAATTCTACAGCCCCCTTCAGGTGGACACCAATGCACTGAAGGCCCAGACCTCGCCACATCCGGCTTTGATGTACGGCCTCAGTCAGCGGTATCTGATGGAGATGTATGCCGCCAAGTCCACATCGCCCTCGGGGAATGAGGGAGTTGTTAACTCGCAGCCACCGGCTCCTCAAGCAaccgcaccaccaccaccaaatGCCAGCACTGCCACTTTCAGTTGCGGAATGTGCGAGCGGCAGGACTTGCGCAGCGAGGCGGAACTGCACTCCCATCGCAAATTGGCCCACAATCTGAAGACGGGCGTCAGCTTGAGATGTGCCTACTGTGCCGGCAACTTTAAGTCTCGCGCCGAACTGGAGCAGCACATGAAGAGCTGTCACAATTCGACGGGCAAGCACAAGTGCTTGATATGCGATGAGGTGTTTCCCTCGCCAGCCATCCTGGCCGAGCACAAGCTGCAGCACTCCAAGGTGGGGCAGTCCGGAAAGTGCTCGCACTGCGGACAACCCCTGGAGGATGTGGCCGCCTTTAGGGCGCATCTATCGGAGCATGGAAGCGATGGTGGCTCCCTGCCACTAGCCTGCATTTGCTGCCGCCAGACGCTGCATTCGGAATTCGAGCTAAGTCTGCATGCCAAATTCCACACAAAGTCCGCCTCGAGTGGCGGCAGTCTGCAGGAGCCAGTGTGTGCTCTGTGCTTGGAGCCCCTACCAGACGCCACCGAGGGTCCGGCCAAACTCTGTGACAAGTGCTGTCGTAAGCATAATCTAAATGGAAAACGTGGCAAGCACTCAGAGCCTTCGGCATCTCTGCCAGCTCCGCCGTCGGCGTTCGTGGAGAACCGCTGCAATCTGTGCAAGATGATCCTGCCACATGCCCAGAAGCTGCAGGAACACCTGGTGGAGCACACCTTTGCCGGCACCGAGCAGCGTGGCTTCAACTGCTACATCTGCTCGGCCGTCTTCACCGCACCCGGCGGACTGCTCAACCACATGGGCGAACACGGAGCCCATTCTCGACCCTACGACTGTAGTCTGTGCCCGGAGAAATTCTACTTCCGAGCCGAGTTGGAGCACCACCAAAGGGGGCACGAGCTGAGACCACAGGCACGCCCGCCAGCATCGAAAGTGGAGATGCCCTCCATTCGGAACAGTTCACCCGGCCAGAGTCCGGTGAGAAGTCCCACCATTGTCAAACAAGAGCTATACGAAACGGATACAGTCGAGTCCGCCGCCGTGGAAGATGAACCGGGGAATCCTCCAGATGACGAGGAGTACATTGAAGTAGAACAAATGCCGCATGAGACACGTCCAAGTGAGATTGGGTCGCAATTGGAAAGGTCCACCAGCAGCGCctga
Protein Sequence
MMALKMLYRGPSSRLENLIEKIQATKEISNNDMYSTHTSSSYSPSISDGTMTPNSHHLPGAPIAAGQEDHPTEGKINGGADGEDLPKPKRLPHFHHHHHHHYHHQQALKIANKLRKINKEAKMGATAGAGSTGGASKFDKLTGEGIKSRGDGSYQCQFCEKTFPRLGYLKHHVQSHAEHLPFKCEYCSKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASASVSSNGSLQKRRYALALASDSSPSRLDFPKRSRSNHVGGTTTTATPTPLLRCSYCPKVTEFSSLEQLNAHLQSVHEQPQQAVKTPVQEGEGFQLSCEYCTMKFGNIAGLFQHMRGTHMDRLSSPNSYYEHFNRLATAGTFSPRLALDLPKIKPDLGSPERESRPAEDDLPTDLSSNKRRPLTPNPQAQAQAPLAPPTAPPGVFFCNQCNAGLPDFESFRNHLKSHIAEGMQLVCPHCGLSLPEQSEFERHVVGHFLITGSEFNCSSSCGKSFAKSEDLQQHLLSEHVLTLLKCSLCSELCESRMAMQLHLACAHSQETKLLRCSACLELFRSDAEFHVHVKTRHQLGGHPTLGATSNAPTNPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGVKEKEANSPNMGSLYVNALLPPLAAAAAAAAATNNNSSIIDYNVAFKGLFGGAAGAAGSGGGGGGGAQAGGAPPSANKFYSPLQVDTNALKAQTSPHPALMYGLSQRYLMEMYAAKSTSPSGNEGVVNSQPPAPQATAPPPPNASTATFSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCAGNFKSRAELEQHMKSCHNSTGKHKCLICDEVFPSPAILAEHKLQHSKVGQSGKCSHCGQPLEDVAAFRAHLSEHGSDGGSLPLACICCRQTLHSEFELSLHAKFHTKSASSGGSLQEPVCALCLEPLPDATEGPAKLCDKCCRKHNLNGKRGKHSEPSASLPAPPSAFVENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPGGLLNHMGEHGAHSRPYDCSLCPEKFYFRAELEHHQRGHELRPQARPPASKVEMPSIRNSSPGQSPVRSPTIVKQELYETDTVESAAVEDEPGNPPDDEEYIEVEQMPHETRPSEIGSQLERSTSSA*