Basic Information

Insect: Drosophila bipectinata
Gene Symbol: L
Assembly: GCA_018153845.1
Location: JAECYF010000002.1:8487355-8493522[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 2.9e-05 0.0022 18.2 2.9 1 23 156 178 156 178 0.98

2 17 0.13 9.7 6.7 7.3 1 23 184 206 184 206 0.97

3 17 1.4e-07 1.1e-05 25.5 3.2 1 23 212 234 212 234 0.99

4 17 1e-05 0.00078 19.6 0.4 1 23 240 262 240 262 0.99

5 17 0.01 0.76 10.2 0.2 2 23 344 368 343 368 0.92

6 17 0.0013 0.095 13.1 0.4 2 23 389 411 388 411 0.96

7 17 0.052 3.9 8.0 0.7 1 23 490 512 490 512 0.97

8 17 0.0037 0.27 11.6 0.1 2 23 520 541 519 541 0.92

9 17 4.3e-05 0.0033 17.7 0.4 1 23 549 573 549 573 0.95

10 17 4.2 3.1e+02 2.0 0.9 2 23 609 631 608 631 0.94

11 17 0.0021 0.16 12.3 1.1 1 23 677 700 677 700 0.97

12 17 0.0042 0.31 11.4 1.2 2 23 889 911 888 911 0.96

13 17 0.034 2.5 8.6 0.1 1 23 917 939 917 939 0.92

14 17 0.041 3 8.3 0.1 2 23 947 968 946 968 0.96

15 17 0.62 47 4.6 0.5 2 23 1072 1093 1072 1093 0.94

16 17 0.0063 0.47 10.9 0.0 1 23 1103 1125 1103 1125 0.96

17 17 0.00019 0.015 15.6 1.2 1 23 1132 1154 1132 1154 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	2.9e-05	0.0022	18.2	2.9	1	23	156	178	156	178	0.98
2	17	0.13	9.7	6.7	7.3	1	23	184	206	184	206	0.97
3	17	1.4e-07	1.1e-05	25.5	3.2	1	23	212	234	212	234	0.99
4	17	1e-05	0.00078	19.6	0.4	1	23	240	262	240	262	0.99
5	17	0.01	0.76	10.2	0.2	2	23	344	368	343	368	0.92
6	17	0.0013	0.095	13.1	0.4	2	23	389	411	388	411	0.96
7	17	0.052	3.9	8.0	0.7	1	23	490	512	490	512	0.97
8	17	0.0037	0.27	11.6	0.1	2	23	520	541	519	541	0.92
9	17	4.3e-05	0.0033	17.7	0.4	1	23	549	573	549	573	0.95
10	17	4.2	3.1e+02	2.0	0.9	2	23	609	631	608	631	0.94
11	17	0.0021	0.16	12.3	1.1	1	23	677	700	677	700	0.97
12	17	0.0042	0.31	11.4	1.2	2	23	889	911	888	911	0.96
13	17	0.034	2.5	8.6	0.1	1	23	917	939	917	939	0.92
14	17	0.041	3	8.3	0.1	2	23	947	968	946	968	0.96
15	17	0.62	47	4.6	0.5	2	23	1072	1093	1072	1093	0.94
16	17	0.0063	0.47	10.9	0.0	1	23	1103	1125	1103	1125	0.96
17	17	0.00019	0.015	15.6	1.2	1	23	1132	1154	1132	1154	0.97

Sequence Information

Coding Sequence: ATGATGGCCCTAAAGATGTTATATCGCGGTCCCAGTTCGCGTTTGGAGAATTTAATTGAAAAGATCCAGGCCACCAAGGAGATAACCAATAACGATATGTATAGTACTCACACATCCTCCAGCTACTCACCCAGCATTTCGGACGGCACCATGACTCCCAACTCACATCACTTGCCCGGTGCTCCTGCCAATCTCCCCGGCCAGGATCAGGATCACCCGAGAGAGGGAAACACCAACGGAGGACTGGATGGCGAGGACTTGGTCAAGCCGAAGCGTCTGCCCCATTTCCATCATCATCACCACCACCACTACCATCACCAGCAGGCGCTGAAAATCGCCAACAAGCTGCGAAAAATCAATAAGGAATCCAAGCTGGGAGCCCTGGGAGGAGCGGGAGCCGGAGGAGTTGGCTCCAAGTTTGATAAGTTGACGGGCGAGGGGATTAAAAGTCGCGGCGACGGCTCCTATCAGTGTCAGTTCTGCGAGAAGTCATTTCCGCGACTCGGTTACTTGAAGCATCACGTGCAGAGCCACGCCGAACACCTGCCCTTCAAGTGCGAGTACTGCTCCAAGCTCTTCAAGCACAAGCGCTCCCGGGATCGCCATAAGAAGCTTCACACCAACGAGAGGAACTACAAGTGTCCTCATTGCGAGGCTGCCTTTTCCAGGAGTGACCATCTTAAGATCCACATGAAAACCCATGACATCCAGAAGCCCTTCCAGTGCAGCATGTGCAACAGGGGCTACAACACGGCAGCTGCCCTGACCTCCCACATGCAGAAGCACAAGAAGAACGCCGCCATCCTGGCAGCTGGAGGCAATCCCAATGCCCTCAACTACAGTCCACGCTCTACGGGATCTGCCTCGGCCTCGGTCTCCAGCAACGGGAGCCTGCACAAGAGGCGATATGCCCTGACCCTGGCCACGGACAGCAGTCCCAGCCGCCTGGACTACCCCCAGAAGAGGTCGAGAAGTGGCACCACCTCCACTGCCGCCGCCACAGCTAATGCAGCACCCACGCCACTGCTGAGGTGCAGCTACTGCCCCAAGGTGACGGAGTTCAGCAGCCTGGAGCAGTTGAATGCCCATCTGCAGAGTGTCCACGAGCAGCCCCAGCAGCCGCCGGTAAAGACACCCAACCAGGAGGCGGAGGGCTTCCAGCTGAGCTGTGAATACTGCACCATGAAGTTCGGCAACATAGCCGGTCTCTTCCAGCACATGCGGAGCACTCACCTGGACAGGCTGAGCAGCCCCAACTCCTACTACGAGCACTTCAACCGCCTGGCCACCGCCGGCACCTTCAGTCCGCGCCTGGCTCTGGATCTGCCCAAGATCAAGCCGGACCTGGGAAGCCCCGATCAGCGCGAGCTGCGGCCGGCGGAGGAGGACCTACCCACGGACTTGAGCAGCAACAAGCGGCGACCCCTGACCCCTAACCCGCAGCCCCCACCCGCTCCTCCGGGCGTCTTCTTCTGCAATCAGTGCAACGCCGGCTTGCCCGACTTCGAGAGCTTCAGGAATCACCTGAAGAGCCACATCGCCGAGGGCATGCAGCAGGTCTGCCCGCACTGTGGACTGAGCCTGCCGGAGCAGTCGGAGTTCGAGCGCCATGTGGTGGGCCACTTCCTGATCACCGGATCGGAGTTCAACTGCAGCTCCAGCTGCGGCAAGAGCTTCGCCAAGTCGGAGGACCTCCAGCAGCACCTCATCACTGAGCACGTCCTCACTCTCCTGAAGTGTTCCCTATGCTCGGAGCTCTGCGAGAGCCGGATGGCCATGCAGCTCCACCTAGCCTGTGCCCACAGCCAGGAGACCAAGCTGCTTCGCTGCAGCGCCTGCCTGGAGCTGTTCCGCTCGGACGCCGAGTTCCACGTCCACGTCAAGACGCGCCACCAGCTGGGCGGACACCCCGCCCTGGGCAGTGCCACTGCGAATGCCCCCTCCAATCCTCTCCAGTGCATGTTCTGCCGAGTGGTCTGCTCCTCGGAGCTGGAAATGCATTTCCATTTGGCGGCCCATGCCAGGCAGTTCCGGTGCCCCTCGTGCCCCGAGACCTTCCACGTTGAGTTCCTGCTGGATCGCCACATGCAGAGCCAGCACGGTGGTGTCGGAGGAGGAGCAGGCGTCAAGGACAAGGAGGCCAGTTCGCCCAACATGAACAGCCTGTACGTGAACGCCCTGCTGCCACCACTTGCGGCAGCAGCAGCGGCTGCCGCAGCCACCAACAACAACAGCAGCATCATCGACTACAACGTGGCCTTCAAGGGCTTGTTTGGCGGAGCAGCCGGAGGAGGAGGAGGAGGGTCTGGAGCACCCACTGCCCCCTCGTCCAAGTTCTACAGCCCGCTGCAAGTGGACACCAACGCCCTGAAGGCACAGACCTCGCCCCACCCGGCCCTGATGTACGGACTCAGCCAGAGGTACTTGATGGAAATGTACGCCGCCAAGTCGGCCTCTCCTCCGGGAAGTGAGGGTGGAGCCAGTGGGCAGGCAGCCGGATCCCAGGCATCTGCACCAGTACCGCCACCCGCTCCTCCTGCACCACCGCAGGCACCACCCACCACCTTCAGCTGCGGAATGTGCGAGCGACAGGATCTGAGGAGCGAGGCGGAACTCCACTCGCACCGCAAACTGGCCCACAACCTGAAGACCGGAGTGAGCCTGAGGTGCGCCTACTGCGCCGGGAACTTCAAGTCCCGGGCGGAGCTGGAGCAGCACATGAAGAGCTGTCACAATTCCACGGGCAAGCACAAGTGCTTGATCTGCGACGAGGTCTTCCCCTCGCCAGCCATCCTGGCCGAGCACAAGCTACAGCACTCCAAGGTGGGGCAGTCGGGCAAGTGCTCGCACTGCGGCCAGCCCCTGGAGGACGTGGCCGCCTTTCGGGCCCACCTCTCCGAGCATGGAAGCGACGGGGCGTCCCTGCCCCTGGCCTGCATCTGCTGCCGCCAGACCCTGCACTCGGAGTTCGAACTGAGTCTGCACGCCAAGTTCCACACCAAGTCCGCGTCCAGTGGCGGCAGCCTCCAGGAGCCAGTGTGTGCCCTGTGCCTGGAGCCCCTGCCGGACGCCACCGAGGGTCCTGCCAAGCTGTGCGAGAAGTGCTGCCGCAAGCACAACCTCAATGGAAAGAGGAGCAAGCCTCCGAGTGAGCCGCCAGTCCAGAGTCTGCCGCCCATCCAGCCGCCATCCGGGGCAGCCTTTGTGGAGAACCGTTGCAACCTGTGCAAGATGATCCTGCCGCACGCCCAGAAGCTGCAGGAGCACCTGGTGGAGCACACCTTTGCCGGCACCGAGCAGCGCGGCTACAATTGCTACATCTGCTCCGCGGTCTTCACAGCACCTGGAGGTCTCCTCAACCACATGGCGGAACATGGCGCCCACACGCGTCCCTACGACTGCAACCTCTGCCCGGAGAAGTTCTACTTCCGGGCGGAGCTGGAGCACCATCAGCGGGGCCACGAGCTGCGACCCCAGGCACGTCCCAAGATGGAAGTGCCCTCCAACAGGACAAGTTCCTCGCCCATCGACAGCCCCGTGAGGAGTCCCACGATCGTCAAGCAGGAGCTGTACGAGACGGATACGGCTCAGTCGGCAGGAGGGGATGAGGAGGAGCCGGAAAACGCCCACGACGACGAGGAATACATCGAGGTGGAGCAAATGCCGCACGAGGGGCGTCCCAGCGAGTTGGAAAGGGCCACCAGTAGCGCCTAA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEITNNDMYSTHTSSSYSPSISDGTMTPNSHHLPGAPANLPGQDQDHPREGNTNGGLDGEDLVKPKRLPHFHHHHHHHYHHQQALKIANKLRKINKESKLGALGGAGAGGVGSKFDKLTGEGIKSRGDGSYQCQFCEKSFPRLGYLKHHVQSHAEHLPFKCEYCSKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASASVSSNGSLHKRRYALTLATDSSPSRLDYPQKRSRSGTTSTAAATANAAPTPLLRCSYCPKVTEFSSLEQLNAHLQSVHEQPQQPPVKTPNQEAEGFQLSCEYCTMKFGNIAGLFQHMRSTHLDRLSSPNSYYEHFNRLATAGTFSPRLALDLPKIKPDLGSPDQRELRPAEEDLPTDLSSNKRRPLTPNPQPPPAPPGVFFCNQCNAGLPDFESFRNHLKSHIAEGMQQVCPHCGLSLPEQSEFERHVVGHFLITGSEFNCSSSCGKSFAKSEDLQQHLITEHVLTLLKCSLCSELCESRMAMQLHLACAHSQETKLLRCSACLELFRSDAEFHVHVKTRHQLGGHPALGSATANAPSNPLQCMFCRVVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGVGGGAGVKDKEASSPNMNSLYVNALLPPLAAAAAAAAATNNNSSIIDYNVAFKGLFGGAAGGGGGGSGAPTAPSSKFYSPLQVDTNALKAQTSPHPALMYGLSQRYLMEMYAAKSASPPGSEGGASGQAAGSQASAPVPPPAPPAPPQAPPTTFSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCAGNFKSRAELEQHMKSCHNSTGKHKCLICDEVFPSPAILAEHKLQHSKVGQSGKCSHCGQPLEDVAAFRAHLSEHGSDGASLPLACICCRQTLHSEFELSLHAKFHTKSASSGGSLQEPVCALCLEPLPDATEGPAKLCEKCCRKHNLNGKRSKPPSEPPVQSLPPIQPPSGAAFVENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGYNCYICSAVFTAPGGLLNHMAEHGAHTRPYDCNLCPEKFYFRAELEHHQRGHELRPQARPKMEVPSNRTSSSPIDSPVRSPTIVKQELYETDTAQSAGGDEEEPENAHDDEEYIEVEQMPHEGRPSELERATSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00548267;
90% Identity: iTF_00615690;
80% Identity: -