Basic Information

Insect: Drosophila azteca
Gene Symbol: L
Assembly: GCA_005876895.1
Location: VCKU01000094.1:11651312-11657960[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 1e-05 0.00082 19.6 3.1 1 23 159 181 159 181 0.98

2 17 0.28 23 5.6 6.2 1 23 187 209 187 209 0.97

3 17 1.3e-07 1.1e-05 25.5 3.2 1 23 215 237 215 237 0.99

4 17 9.9e-06 0.00081 19.6 0.4 1 23 243 265 243 265 0.99

5 17 0.017 1.4 9.5 0.2 2 23 341 365 340 365 0.91

6 17 0.0031 0.25 11.8 0.2 2 23 395 417 394 417 0.95

7 17 0.049 4 8.0 0.7 1 23 499 521 499 521 0.97

8 17 0.0041 0.34 11.4 0.1 2 23 529 550 528 550 0.91

9 17 0.00022 0.018 15.4 0.2 1 23 558 582 558 582 0.95

10 17 1 85 3.8 0.9 2 23 618 640 617 640 0.95

11 17 0.002 0.17 12.3 1.1 1 23 685 708 685 708 0.97

12 17 0.004 0.32 11.4 1.2 2 23 890 912 889 912 0.96

13 17 0.091 7.5 7.1 0.1 1 23 918 940 918 940 0.92

14 17 2 1.7e+02 2.9 0.6 2 23 948 969 948 969 0.95

15 17 0.59 48 4.6 0.5 2 23 1069 1090 1069 1090 0.94

16 17 0.056 4.6 7.8 0.0 1 23 1100 1122 1100 1122 0.96

17 17 0.00018 0.014 15.7 1.2 1 23 1129 1151 1129 1151 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	1e-05	0.00082	19.6	3.1	1	23	159	181	159	181	0.98
2	17	0.28	23	5.6	6.2	1	23	187	209	187	209	0.97
3	17	1.3e-07	1.1e-05	25.5	3.2	1	23	215	237	215	237	0.99
4	17	9.9e-06	0.00081	19.6	0.4	1	23	243	265	243	265	0.99
5	17	0.017	1.4	9.5	0.2	2	23	341	365	340	365	0.91
6	17	0.0031	0.25	11.8	0.2	2	23	395	417	394	417	0.95
7	17	0.049	4	8.0	0.7	1	23	499	521	499	521	0.97
8	17	0.0041	0.34	11.4	0.1	2	23	529	550	528	550	0.91
9	17	0.00022	0.018	15.4	0.2	1	23	558	582	558	582	0.95
10	17	1	85	3.8	0.9	2	23	618	640	617	640	0.95
11	17	0.002	0.17	12.3	1.1	1	23	685	708	685	708	0.97
12	17	0.004	0.32	11.4	1.2	2	23	890	912	889	912	0.96
13	17	0.091	7.5	7.1	0.1	1	23	918	940	918	940	0.92
14	17	2	1.7e+02	2.9	0.6	2	23	948	969	948	969	0.95
15	17	0.59	48	4.6	0.5	2	23	1069	1090	1069	1090	0.94
16	17	0.056	4.6	7.8	0.0	1	23	1100	1122	1100	1122	0.96
17	17	0.00018	0.014	15.7	1.2	1	23	1129	1151	1129	1151	0.97

Sequence Information

Coding Sequence: ATGATGGCCCTAAAAATGCTTTATCGCGGTCCCAGTTCGCGTTTGGAGAATCTAATTGAGAAGATCCAGGCCACCAAGGAGATCACAAATAACGACATGTACAGTACCCACACCTCGTCCAGCTACTCGCCGAGCATCTCCGATGGGACCATGACACCCAATTCCCATCATCTGGCTGCTACCTCGGCGAATGCCGGCCAGGAGGATCTCCATCAGACGGCTGAAGGCAAGTCGAACGGAGTCCCAGGAGAGGAGCCTGCCAAGCCAAAGCGACAGCCGCTCttccaccaccaccaccatcactACCATCACCAGCAGGCCCTGAAGATTGCCAACAAGCTGCGCAAAATCAATAAGGAGGCCAAGATGACAGctgcaggaggagcaggagccggAACTGGCGCTGGCGGTGGAGCAGCCGCAAAGTTTGATAAGTTGACAGGCGAAGGCATTAAGAGTCGCGGCGACGGCTCCTATCAGTGCCAGTTCTGTGATAAGACATTTCCGCGTCTCGGCTACTTGAAGCATCACGTGCAGAGCCATGCCGAGCATCTGCCCTTCAAGTGCGAGTACTGCGCCAAGCTGTTCAAGCACAAGCGCTCCCGGGACCGCCATAAGAAGCTGCACACCAACGAGCGCAACTACAAGTGTCCGCACTGCGAGGCGGCCTTCTCCAGGAGCGATCACCTGAAGATCCACATGAAGACGCATGACATCCAGAAGCCCTTCCAGTGCAGCATGTGCAACAGGGGCTACAACACGGCCGCGGCCCTCACCTCACACATGCAGAAGCACAAGAAGAACGCCGCAATCCTGGCAGCCGGCGGCAATCCCAATGCCCTCAACTACAGTCCCCGCTCCACGGGCTCTGCCTCGGCCTCGGTGTCCAGCAATGGAAGCCTGCACAAGCGGCGCTatgccctggccctggccacCGACAGCAGTCCCAGTCGCCTGGACTTCCCCAAGAGATCGCGCGGCAGTCATGTGGCCAGCACACCCACGCCAACGCCTCTGCTGAGATGCAGCTACTGCCCCAAGGTGACAGAGTTCAGCAGCTTGGAGCAGCTGAATGCCCATCTCCAGAATGTCCACGAGCAGACGCAGCCaccacagcagcagccccagcaacagcagcagtcgGCGAAGACTTCCGTCCAGGAGGGAGAGGGTTTCCAGCTGAGCTGCGAGTACTGCACCATGAAGTTTGGCAACATTGCCGGACTCTTCCAGCACATGCGCGCCACCCATCTAGATCGTCTGAGCAGCCCCAACTCCTACTACGAGCACTTCAATCGCCTGGCCACAGCCGGCACATTCAGTCCACGGCTGGCTCTGGATCTACCCAAGATCAAGACGGATCTGGGCAGTCCCGAACGAGAGAACCGACCCTCCGAGGACGACCTTCCAACGGATCTGAGCAGCAACAAGCGTCGACCGCAGACACCCAACGCTCCGCCGAATCCTCCGCAAGCGCCCGCCCCACCCGGCATCTTCTTCTGCAATCAGTGCAACGCCGGACTTCCCGACTTTGAGAGCTTCCGCAACCACCTGAAGAGCCACATTGCCGAGGGAATGCAGCTGATCTGTCCCCACTGTGGGCTGAGCCTCCCGGAGCAGTCCGAGTTTGAGCGCCACGTGGTGGGACACTTCCTGATCCCCAACTCCGAGTTCAACTGCAGCTCCAGCTGCGGCAAGAGCTTCGGCAAGGCcgaggagctgcagcagcatcTCATCACCGAGCACGTGCTCACCCTGCTCAAGTGTGCCCTCTGTTCGGAGACGTGCGAGACGCGGATGGCCATGCAGCTGCACCTGGCCTGCGCCCACTGCCAGGAGACGAAGCTGCTGCGCTGCAGCGCCTGCATGGAGGTCTTCCGTTCCGATGGCGACTTCCATGTGCACGTCAAGACGCGCCACCAGCTGGGGAATCATCACCACCCGAtgggcggcagcagcagtccGGCCAACCCGCTGCAGTGCATGTTCTGCCGGGCCGTCTGCTCCTCTGAGCTGGAGATGCACTTCCATCTGGCGGCCCATGCGCGACAGTTCCGCTGCCCATCCTGTCCGGAGACCTTTCACGTGGAGTTCCTGCTCGACAGGCACATGCAGAGCCAGCATGGCGGCGTCAAGGACAAGGAGCAGCCGCAACAAAGCTCCCCCAACATGGGCAGCCTCTACGTGAACGCCCTGCTGCCTCCTCTTGCCGCAGCagccgctgctgcagctgccaccaacaacaacagtagCATCATCGACTACAACGTGGCCTTCAAGGGGCTGTTCGGCGGAGGATCGGCAGGAGGGAGTGCACCCACAGGTCCCTCGGCGGCCGGCAAGTTCTACAGCCCCCTGCAGGTGGACACGAATGCCCTGAAGGCGCAGACCTCCCCCCATCCCGCCCTGATGTACGGCCTCAGCCAGCGGTATCTGATGGAGATGTATGCCGCCAAGTCCACGTCCCCGGCCAACAGTGCCGCCAACGAATCAGCAGGAGGAGGAACCTCCTCCATCAATGCCCCGCCAGCGCCACAGGCGCCGCCGCCCCCCGCACCAGCTGTCACCTTCAGCTGTGGGATGTGCGAGCGCCAGGATCTGCGCAGCGAGGCGGAACTCCACTCACACCGGAAACTAGCCCACAACCTGAAGACGGGCGTGAGCCTGCGGTGCGCCTACTGTGCGGGCAACTTCAAGTCGCGGGCGGAGCTCGAGCAGCACATGAAGAGCTGCCACAACTCGACGGGCAAGCACAAGTGCCTCATCTGCGACGAGATCTTCCCCTCGCCGGCCATCCTGGCCGAGCACAAGCTGCAGCACTCGAAGGTGGGCCAGTCGGGCAAGTGCGCCCACTGCAGCCACCCGCTGGAGGATGTGGCCGCCTTCCGGGCCCATCTCAGCGAGCATGGCAGCGATGGAGCCTCCCTGCCCCTGGCCTGCATCTGCTGTCGCCAGACCCTTCACTCGGAGTTCGAGCTGAGCCTCCATGCCAAGTTTCACACGAAGTCCTCGTCCAGTGGCGGCAGCCTCCAGGAACCAGTTTGCGCCCTCTGCCTGGAGCCCCTGCCAGGGGCAGTGGAGGGTCCCACCACTCCGGCCAAGCTCTGCGAAAAGTGTTGCCGCAAGCACAACCTCAACGGCAAGCGGAGCAAGGCCAGCGAGGCCCCTGTGGTCCAGGCCCAGCCGACTCCCTACCTGGAGAACCGCTGCAACCTGTGCAAGATGATCCTGCCGCATGCCCAGAAGCTGCAGGAGCACCTGGTGGAGCACACCTTCGCTGGCACCGAGCAGCGCGGCTTCAATTGCTACATCTGCTCGGCCGTGTTCACGGCCCCTGGCGGTCTCCTTGGCCACATGGCCGAGCACGGAGCCCACTCGCGTCCCTACGACTGCAATCTCTGCCCCGAGAAGTTCTACTTCCGTGCCGAGCTGGAACACCACCAGCGGGCACACGAGCTGAGGCCCTCGGTTCGTCCATCAGTCGACAAAGCAGAGCCCCCGATGCGGGCCAGTGCGTCGCCCAGTCCAAGTCCGGTTCGAAGTCCCACAACCGTTAAGCAGGAGCTGTACGACACGGACACGGGTCACTCTGGGGCCGGCGATGATGAGCCAGAGCCCGCCCAGGATGAGGAGGAGTACATAGAGGTGGAGCAGATTCCGCACGAGACGCGGCCAAGGGATGTCATGTCACAGATGGAAAGGGCCACAAACAGCGCCTAA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEITNNDMYSTHTSSSYSPSISDGTMTPNSHHLAATSANAGQEDLHQTAEGKSNGVPGEEPAKPKRQPLFHHHHHHYHHQQALKIANKLRKINKEAKMTAAGGAGAGTGAGGGAAAKFDKLTGEGIKSRGDGSYQCQFCDKTFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASASVSSNGSLHKRRYALALATDSSPSRLDFPKRSRGSHVASTPTPTPLLRCSYCPKVTEFSSLEQLNAHLQNVHEQTQPPQQQPQQQQQSAKTSVQEGEGFQLSCEYCTMKFGNIAGLFQHMRATHLDRLSSPNSYYEHFNRLATAGTFSPRLALDLPKIKTDLGSPERENRPSEDDLPTDLSSNKRRPQTPNAPPNPPQAPAPPGIFFCNQCNAGLPDFESFRNHLKSHIAEGMQLICPHCGLSLPEQSEFERHVVGHFLIPNSEFNCSSSCGKSFGKAEELQQHLITEHVLTLLKCALCSETCETRMAMQLHLACAHCQETKLLRCSACMEVFRSDGDFHVHVKTRHQLGNHHHPMGGSSSPANPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGVKDKEQPQQSSPNMGSLYVNALLPPLAAAAAAAAATNNNSSIIDYNVAFKGLFGGGSAGGSAPTGPSAAGKFYSPLQVDTNALKAQTSPHPALMYGLSQRYLMEMYAAKSTSPANSAANESAGGGTSSINAPPAPQAPPPPAPAVTFSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCAGNFKSRAELEQHMKSCHNSTGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCSHPLEDVAAFRAHLSEHGSDGASLPLACICCRQTLHSEFELSLHAKFHTKSSSSGGSLQEPVCALCLEPLPGAVEGPTTPAKLCEKCCRKHNLNGKRSKASEAPVVQAQPTPYLENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPGGLLGHMAEHGAHSRPYDCNLCPEKFYFRAELEHHQRAHELRPSVRPSVDKAEPPMRASASPSPSPVRSPTTVKQELYDTDTGHSGAGDDEPEPAQDEEEYIEVEQIPHETRPRDVMSQMERATNSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00548267;
90% Identity: iTF_00611560;
80% Identity: -