Basic Information

Insect: Drosophila serrata
Gene Symbol: L
Assembly: GCA_002093755.1
Location: NW:22634-56075[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 1e-05 0.00066 19.7 2.9 1 23 304 326 304 326 0.98

2 17 0.15 10 6.5 7.3 1 23 332 354 332 354 0.97

3 17 1.7e-07 1.1e-05 25.3 3.2 1 23 360 382 360 382 0.99

4 17 1.2e-05 0.00081 19.4 0.4 1 23 388 410 388 410 0.99

5 17 0.013 0.81 10.0 0.2 2 23 494 518 493 518 0.92

6 17 0.00021 0.013 15.6 0.7 2 23 540 562 539 562 0.96

7 17 0.062 4 7.8 0.7 1 23 650 672 650 672 0.97

8 17 0.0042 0.27 11.5 0.1 2 23 680 701 679 701 0.92

9 17 9.4e-05 0.0061 16.7 0.4 1 23 709 733 709 733 0.94

10 17 5 3.3e+02 1.8 0.9 2 23 769 791 768 791 0.94

11 17 0.0026 0.17 12.1 1.1 1 23 836 859 836 859 0.97

12 17 0.005 0.32 11.2 1.2 2 23 1052 1074 1051 1074 0.96

13 17 0.04 2.6 8.4 0.1 1 23 1080 1102 1080 1102 0.92

14 17 0.049 3.1 8.1 0.1 2 23 1110 1131 1109 1131 0.96

15 17 0.74 48 4.4 0.5 2 23 1237 1258 1237 1258 0.94

16 17 0.0097 0.63 10.3 0.0 1 23 1268 1290 1268 1290 0.96

17 17 0.00017 0.011 15.8 1.7 1 23 1297 1319 1297 1319 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	1e-05	0.00066	19.7	2.9	1	23	304	326	304	326	0.98
2	17	0.15	10	6.5	7.3	1	23	332	354	332	354	0.97
3	17	1.7e-07	1.1e-05	25.3	3.2	1	23	360	382	360	382	0.99
4	17	1.2e-05	0.00081	19.4	0.4	1	23	388	410	388	410	0.99
5	17	0.013	0.81	10.0	0.2	2	23	494	518	493	518	0.92
6	17	0.00021	0.013	15.6	0.7	2	23	540	562	539	562	0.96
7	17	0.062	4	7.8	0.7	1	23	650	672	650	672	0.97
8	17	0.0042	0.27	11.5	0.1	2	23	680	701	679	701	0.92
9	17	9.4e-05	0.0061	16.7	0.4	1	23	709	733	709	733	0.94
10	17	5	3.3e+02	1.8	0.9	2	23	769	791	768	791	0.94
11	17	0.0026	0.17	12.1	1.1	1	23	836	859	836	859	0.97
12	17	0.005	0.32	11.2	1.2	2	23	1052	1074	1051	1074	0.96
13	17	0.04	2.6	8.4	0.1	1	23	1080	1102	1080	1102	0.92
14	17	0.049	3.1	8.1	0.1	2	23	1110	1131	1109	1131	0.96
15	17	0.74	48	4.4	0.5	2	23	1237	1258	1237	1258	0.94
16	17	0.0097	0.63	10.3	0.0	1	23	1268	1290	1268	1290	0.96
17	17	0.00017	0.011	15.8	1.7	1	23	1297	1319	1297	1319	0.98

Sequence Information

Coding Sequence: ATGTCCCGACGCAAACAGGCCAAGCCGCGCGCCTGTCTCAAACTTGGCGAAAAGGAGGATGAGGAAAACACTGGCCTGCTGGAGCCCAAGGAGGAGCTTCTCAGTGGCGATGAGGAGGTCGAGGATaatgaggacgaggacgaggaggagacGCCCGAGGGAGACGCAGGGCTgaaccaggagcaggaggagcagcccAATGAATCACAGCAACAATGCTGGCCAACAGCTGATGAGCCAGTGGCCCCAGCTGCAGTGGCAaaagaagaagcagaagaaCTACAACACCCACGGGATGAGGTAGTTGCatctgatgctgatgctgctgctaccactgccactgctgctgctgctgctgccaatgCCAACGGACACTGCAAGTCCTCTGGCGGAGACGAAGAGGAGGCGGACCCAGATGCGGATCCAGAGACCGAGGACCTAGAGCTGGAAGAGGACCTGCTCAGTCTCAGCGGAGACGACGAGGACTACGATGATGAGGAGCTGCAGAGCCTGGACAGCTTCTATTCAGACATGTACAGTACCCATACATCATCCAGTTACTCGCCTAGCATTTCGGATGGCACCATGACGCCCAATTCCCACCATTTGCCCGGAGCTCCCACCTCTGCCACCGCCTCGGGCCAAGAAGATCATCATCATTCGTCCGAGGGCAAACTCAATGGTGGCCACGATGGCGAGGAGTTGGCCAAACCAAAGCGATTGCCACACttccatcatcatcaccatcatcattaCCACCATCAGCAGGCGCTGAAAATCGCCAACAAGCTGCGCAAAATCAATAAAGAAGCCAAAATGGGAGCTGGCGGTGGTGCTGGTGCCGGAGGAGCAGGCTCCAAGTTTGATAAGTTGACAGGCGAGGGGATTAAGGCCCGCGGCGACGGCTCCTATCAGTGTCAGTTCTGCGATAAGTCATTTCCGCGTCTCGGCTACTTGAAGCATCACGTGCAGAGCCACGCCGAACACCTGCCCTTCAAGTGTGAATACTGCTCGAAGCTGTTCAAGCACAAGCGTTCCCGTGATCGCCATAAGAAGCTGCATACCAACGAGCGTAACTACAAGTGTCCCCATTGTGAGGCAGCCTTCTCCAGGAGTGACCACCTGAAGATCCACATGAAGACGCACGACATCCAGAAGCCGTTCCAGTGCAGCATGTGCAACAGAGGCTATAATACGGCAGCTGCTCTGACCTCGCACATGCAAAAGCATAAGAAGAATGCAGCCATCCTGGCAGCTGGGGGTAATCCCAATGCCCTGAACTATAGTCCGCGATCCACGGGATCAGCCTCGGCTTCGGTCTCCAGCAATGGAAGTCTTCAAAAGAGGCGATATGCTTTAGCTCTAGCTTCGGATAGTAGTCCCAGTAGGTTGGACTACCCCAAGAGATCGAGGAGCAGTCATGTGGGTGGTAATGGAGGTGGCACCACCACTGCAACAGCCACACCCACACCCTTGCTCAGGTGCAGCTATTGTCCCAAGGTCACGGAGTTTACCAGCTTGGAGCAGCTAAATGCCCACCTGCAGAGTGTCCacgagcagcagcatcagcatccaGCAAAGGCACCAGTGGCTCCGGAGAGTGAAGGCTTCCAGCTGAGCTGCGAATATTGCACCATGAAGTTTACCAATATAGCTGGATTATTCCAGCACATGAGGAGCACTCACCTGGACAGATTGAGCAGTCCAAACTCCTACTACGAGCACTTCAATCGCCTGGCCACTGCTGGTACATTCAGTCCTCGTCTGGCCCTGGATTTGCCCAAAATCAAACCGGATTTGGGCAGTCCGGAGAGGGAGACCACGCGTGCGGTTGAGGAGGATCTGCCCACCGATTTGAGCAGCAACAAGAGGCGATCCCAGACACCCACAAATACCCAACAATTGCAGGCCCAACAATTGGCTCCTCCGGCAGCTCCTCCTGGAGTGTTCTTTTGCAATCAATGCAATGCCGGTCTGCCGGATTTCGAGAGCTTCAGGAATCACCTAAAGAGTCATATTGCCGAAGGCATGCAAATGGTGTGTCCCCACTGTGGATTGAGTCTGCCAGAGCAGTCGGAGTTCGAGCGTCATGTGGTGGGACACTTCCTCATCACCGGATCGGAGTTTAACTGCAGCTCCAGCTGTGGCAAGAGCTTTGCCAAGTCGGAGGATCTGCAGCAGCATCTGTTGTCCGAACATGTACTCACCCTGCTGAAGTGCTCCCTATGCTCGGAGCTCTGCGAGAGTCGGATGGCCATGCAACTGCATCTGGCCTGTGCCCACAGCCAGGAGACGAAGTTACTCCGTTGCAGCGCCTGCCTGGAGCTCTTCCGTTCCGATGCCGAGTTCCATGTGCATGTGAAGACGCGTCACCAGCTGGGAGGACATCCCTCACTCGGAGCCACACCCAATGCTCCGGCCAATCCCCTGCAGTGTATGTTCTGCCGGGCTGTGTGCTCTTCGGAGCTGGAGATGCACTTCCATTTGGCGGCACATGCAAGGCAGTTTAGATGCCCCTCCTGCCCGGAGACATTCCACGTGGAGTTCCTGCTGGATAGGCATATGCAGAGTCAGCATGGTGGCGGCGTCAAGGACAAGGAGCAGCAACGTGGCTCACCCAACATGGGGAGTCTCTATGTGAATGCCTTGTTGCCTCCCctggcagcagcggcagctgcagcagcggccaccaataacaacagcagcatcatTGACTACAATGTGGCTTTCAAGGGTTTGTttggaggtggaggaggagcaggtggaggaggaggagcagcttctGGAGCGGGATCAGGTTCAGGAGGAGGCTCTGGAGCAGCCCCACCCACGGGCAACAAGTTCTACAGTCCCCTGCAGGTGGACACCAATGCCTTGAAGGCTCAAACCTCACCGCATCCCGCTCTCATGTATGGCCTGAGTCAGCGCTATCTGATGGAGATGTATGCCGCCAAGTCCACCTCGCCGGCGGGAGGAAACGAGGGTAATCCACAGCCACCACAGGCTAGTGCTCCGCCAAGTGCTCCACCGAGTGCTGCTCCAACAGCTGCCACCTTCAGTTGTGGAATGTGCGAACGTCAGGATCTGCGCAGCGAGGCGGAACTCCACTCTCACCGGAAGTTGGCCCATAATCTCAAAACAGGAGTGAGCTTAAGGTGTGCCTACTGTGCCGGGAACTTCAAGTCCCGGGCGGAGCTGGAGCAGCACATGAAGAGCTGTCACAATTCGACGGGCAAGCACAAGTGTCTGATCTGCGATGAGGTCTTTCCCTCGCCGGCCATCCTGGCCGAGCACAAGCTGCAGCACTCGAAGGTGGGTCAGTCTGGCAAGTGTTCCCACTGTGGACAGCCTCTCGAGGATGTGGCTGCCTTTAGGGCTCATCTCTCGGAGCATGGCAGTGATGGTGCCACCCTGCCCTTGGCCTGCATCTGCTGCCGCCAGACCCTTCATTCGGAGTTTGAGCTAAGTCTGCATGCCAAGTTCCACACCAAGTCGGCCTCCAGTGGAGGTAGCCTCCAGGAGCCAGTGTGTGCTCTGTGCCTGGAACCACTGCCCGATGTACCAGTCGAGGGTCCAGCCAAGCTGTGTGAGAAATGCTGTCGCAAGCACAATCTTAATGGAAAGCGGGGTAAGCCAAGTGAGCAGTCGCTGCAGCCACCTCcatcagcaggagcaggatcaggatcaggcGCCGCCTATGTGGAGAACCGCTGCAACCTGTGCAAGATGATCCTGCCGCATGCCCAGAAGCTCCAAGAACACCTGGTGGAGCACACCTTTGCGGGCACCGAGCAGCGTGGCTTCAATTGCTACATCTGCTCAGCGGTATTTACAGCACCGGGGGGTTTACTCAATCACATGGCAGAGCATGGTGCTCATTCGCGTCCCTATGACTGCAGCCTGTGTCCGGAGAAGTTCTACTTCCGGGCGGAGCTGGAGCATCATCAGAGGAGTCACGAGCTGAGGCCACAGGCAACGCGGCCACCTATGCCGAAGGTGGAGGCACCCTCAATTAGGAATAGTTCACCCATCTGCGAGAGTCCTCCTTCCAGGAGTCGCAGTCCCACAATCAATGTCAAGCAGGAACTCTACGAAACGGATACAGTGGAGTCGGGAGCAGGAGAAGATGAGCCGGAAGAGAATCCTCAAGAAGATGAGGAGTACATAGAAGTGGAGCAGGTGCCGCATGAGACAAGAACCAATGAGATGGGTTCACAAATGGAAAGGTCCACCAGTAGCGCCTAG
Protein Sequence: MSRRKQAKPRACLKLGEKEDEENTGLLEPKEELLSGDEEVEDNEDEDEEETPEGDAGLNQEQEEQPNESQQQCWPTADEPVAPAAVAKEEAEELQHPRDEVVASDADAAATTATAAAAAANANGHCKSSGGDEEEADPDADPETEDLELEEDLLSLSGDDEDYDDEELQSLDSFYSDMYSTHTSSSYSPSISDGTMTPNSHHLPGAPTSATASGQEDHHHSSEGKLNGGHDGEELAKPKRLPHFHHHHHHHYHHQQALKIANKLRKINKEAKMGAGGGAGAGGAGSKFDKLTGEGIKARGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCSKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASASVSSNGSLQKRRYALALASDSSPSRLDYPKRSRSSHVGGNGGGTTTATATPTPLLRCSYCPKVTEFTSLEQLNAHLQSVHEQQHQHPAKAPVAPESEGFQLSCEYCTMKFTNIAGLFQHMRSTHLDRLSSPNSYYEHFNRLATAGTFSPRLALDLPKIKPDLGSPERETTRAVEEDLPTDLSSNKRRSQTPTNTQQLQAQQLAPPAAPPGVFFCNQCNAGLPDFESFRNHLKSHIAEGMQMVCPHCGLSLPEQSEFERHVVGHFLITGSEFNCSSSCGKSFAKSEDLQQHLLSEHVLTLLKCSLCSELCESRMAMQLHLACAHSQETKLLRCSACLELFRSDAEFHVHVKTRHQLGGHPSLGATPNAPANPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGGVKDKEQQRGSPNMGSLYVNALLPPLAAAAAAAAATNNNSSIIDYNVAFKGLFGGGGGAGGGGGAASGAGSGSGGGSGAAPPTGNKFYSPLQVDTNALKAQTSPHPALMYGLSQRYLMEMYAAKSTSPAGGNEGNPQPPQASAPPSAPPSAAPTAATFSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCAGNFKSRAELEQHMKSCHNSTGKHKCLICDEVFPSPAILAEHKLQHSKVGQSGKCSHCGQPLEDVAAFRAHLSEHGSDGATLPLACICCRQTLHSEFELSLHAKFHTKSASSGGSLQEPVCALCLEPLPDVPVEGPAKLCEKCCRKHNLNGKRGKPSEQSLQPPPSAGAGSGSGAAYVENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPGGLLNHMAEHGAHSRPYDCSLCPEKFYFRAELEHHQRSHELRPQATRPPMPKVEAPSIRNSSPICESPPSRSRSPTINVKQELYETDTVESGAGEDEPEENPQEDEEYIEVEQVPHETRTNEMGSQMERSTSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00548267;
90% Identity: iTF_00488807;
80% Identity: -