Basic Information

Insect: Drosophila ficusphila
Gene Symbol: L_1
Assembly: GCA_018152265.1
Location: JAECXK010000407.1:6605642-6642327[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 4.3e-05 0.0031 17.7 3.0 1 23 318 340 318 340 0.98

2 17 0.16 11 6.6 7.3 1 23 346 368 346 368 0.97

3 17 1.7e-07 1.2e-05 25.3 3.2 1 23 374 396 374 396 0.99

4 17 1.3e-05 0.00089 19.4 0.4 1 23 402 424 402 424 0.99

5 17 0.012 0.87 10.0 0.2 2 23 504 528 503 528 0.92

6 17 0.0015 0.11 12.9 0.4 2 23 548 570 547 570 0.96

7 17 0.062 4.4 7.8 0.7 1 23 654 676 654 676 0.97

8 17 0.0035 0.25 11.7 0.1 2 23 684 705 683 705 0.91

9 17 9.5e-05 0.0068 16.7 0.4 1 23 713 737 713 737 0.94

10 17 5 3.6e+02 1.8 0.9 2 23 773 795 772 795 0.94

11 17 0.0026 0.18 12.2 1.1 1 23 840 863 840 863 0.97

12 17 0.005 0.36 11.2 1.2 2 23 1044 1066 1043 1066 0.96

13 17 0.041 2.9 8.4 0.1 1 23 1072 1094 1072 1094 0.92

14 17 0.049 3.5 8.1 0.1 2 23 1102 1123 1101 1123 0.96

15 17 0.75 53 4.4 0.5 2 23 1223 1244 1223 1244 0.94

16 17 0.02 1.4 9.4 0.0 1 23 1254 1276 1254 1276 0.95

17 17 0.0019 0.13 12.6 1.5 1 23 1283 1305 1283 1305 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	4.3e-05	0.0031	17.7	3.0	1	23	318	340	318	340	0.98
2	17	0.16	11	6.6	7.3	1	23	346	368	346	368	0.97
3	17	1.7e-07	1.2e-05	25.3	3.2	1	23	374	396	374	396	0.99
4	17	1.3e-05	0.00089	19.4	0.4	1	23	402	424	402	424	0.99
5	17	0.012	0.87	10.0	0.2	2	23	504	528	503	528	0.92
6	17	0.0015	0.11	12.9	0.4	2	23	548	570	547	570	0.96
7	17	0.062	4.4	7.8	0.7	1	23	654	676	654	676	0.97
8	17	0.0035	0.25	11.7	0.1	2	23	684	705	683	705	0.91
9	17	9.5e-05	0.0068	16.7	0.4	1	23	713	737	713	737	0.94
10	17	5	3.6e+02	1.8	0.9	2	23	773	795	772	795	0.94
11	17	0.0026	0.18	12.2	1.1	1	23	840	863	840	863	0.97
12	17	0.005	0.36	11.2	1.2	2	23	1044	1066	1043	1066	0.96
13	17	0.041	2.9	8.4	0.1	1	23	1072	1094	1072	1094	0.92
14	17	0.049	3.5	8.1	0.1	2	23	1102	1123	1101	1123	0.96
15	17	0.75	53	4.4	0.5	2	23	1223	1244	1223	1244	0.94
16	17	0.02	1.4	9.4	0.0	1	23	1254	1276	1254	1276	0.95
17	17	0.0019	0.13	12.6	1.5	1	23	1283	1305	1283	1305	0.98

Sequence Information

Coding Sequence: ATGTCCCGACGCAAACAGGCCAAGCCGCGCGCCTGTCTCAAACTTGGCGAGAAGGAGGACGAGGAGAACACTGGGCTGCTGGAGCCCAAAGAGGAGCTGCTCAGCGGCGACGAGGACAACGAGGATAATGAGGACGAGGACGAGGAGCTGGCCGATGGAGAGTCGGCCGAGGGAGGGGAGCAGCAGCCCCATCCCCAGCCCCAGCTCGAGCCCAATGAATCACAGCAACAAAGCTGGCCAACAGCTGATGAGCCAGCGGTCCCAGCTGCAGTGGCAAAAGAAGAAGAAGACGGACCAGAAGAACTACAACACCCACGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAAGTCCTCTGGCCAAGACGATGCGGATGCGGATGCGGATCCCGAGGCGGAGGCGGAAGTGGAGGAGCCTGAACCAGAGGATTTGGATCTGGATGAGGAGCTGCTCAGTCTCAGCGGGGACGAGGACTACGACGACGAGGAGCTGCAGAGCCTGGACAGCTTCTACTCAGATATGTACAGCACCCACACCTCGTCCAGTTATTCACCAAGTATTTCTGACGGCACCATGACTCCGAACTCCCACCATCTGCCAGGAGCTCCCAATCCGGCTGGCCAGGAGGATCACCATCCTTCCGAGGGCAAAGCCAATGGAGGCGCCGAGGGCGAGGAGTTGCCCAAGCCGAAGCGCTTGCCCCACTTCCACCACCACCACCACCACCACTACCACCACCAGCAGGCGCTGAAAATAGCCAACAAGCTGCGCAAAATCAATAAGGAAACCAAGATGGGAGCCGCCGCAGGTGCGGGATCCGCAGGAGCGGGCTCCAAGTTTGATAAGCTGACAGGGGAGGGGATTAAAAGTCGCGGCGACGGCTCCTATCAGTGTCAGTTCTGCGAGAAGACATTTCCGCGACTCGGCTACTTGAAGCATCACGTGCAGAGCCACGCTGAACACCTGCCTTTCAAGTGCGAGTACTGCTCGAAGCTCTTCAAGCACAAGCGATCCCGCGATCGCCACAAGAAGTTGCACACCAACGAGCGGAACTACAAGTGTCCGCATTGCGAGGCAGCCTTCTCAAGGAGTGACCACTTGAAGATCCACATGAAAACCCATGACATCCAGAAACCCTTTCAATGCAGCATGTGCAACAGGGGTTACAATACCGCTGCGGCGTTGACCTCCCACATGCAGAAGCACAAGAAGAATGCCGCTATCTTGGCAGCTGGTGGCAACCCCAATGCCCTCAACTACAGTCCTCGATCCACAGGATCTGCCTCGGCTTCGGTTTCCAGCAATGGCAGTCTCCAAAAGAGGCGATATGCCTTGGCTTTGGCTTCGGACAGCAGTCCCAGTAGATTGGATTTCCCCAAGAGATCGAGGAGTGGCAACTTGGGTGGCACCACCACCACAACTGCCACGCCCACTCCGATGCTGAGATGCAGCTACTGCCCCAAGGTCACCGAGTTCAGCAGTCTGGAGCAACTGAACGCCCATCTGCAGAGTGTCCACGAACAGCAGCCAACTGGGAAGAGTGCTCCTGGTCAGGAGGGGGAAACCTTCCAGCTGAGCTGTGAGTACTGCACCATGAAGTTCGGCAACATCGCCGGACTTTTCCAGCACATGAGGAGCACCCACATGGACAGGTTGAGCAGCCCGAATTCTTACTACGAGCACTTCAATCGTTTGGCCACCGCGGGAACTTTCAGTCCGAGATTGGCATTGGATTTGCCGAAGATTAAACAGGATCTGGGAAGTCCTGAGAGGGAATCGCGGCAGGCGGAAGAGGATCTGCCCACGGATCTGAGCAGCAACAAGCGGAGACCTTTGACCCCGAATCCACCAAGTCAAACCCAACTAGCACCACCATCTGCGCCACCGGGTGTCTTCTTCTGCAATCAGTGCAATGCTGGACTTCCGGACTTCGAGAGCTTCAGGAATCATCTGAAGAGTCACATTGCCGAGGGAATGCAGTTGGTGTGTCCCCATTGCGGGCTGAGTTTGCCGGAGCAATCGGAGTTCGAGCGCCATGTGGTGGGTCACTTCCTCATCACGGGTTCCGAGTTCAACTGCAGTTCGAGTTGCGGCAAGAGCTTCGCCAAGTCCGAGGATCTGCAGCAACATCTCCTTTCGGATCACGTTCTAACCCTTCTGAAGTGTTCGCTGTGCTCGGAACTCTGTGAGAGTCGAATGGCCATGCAGCTCCACTTGGCCTGTGCTCACAGTCAGGAGACAAAGCTCCTCCGCTGCAGCGCCTGCTTGGAGCTCTTCCGCTCGGACGCCGAGTTCCATGTGCATGTCAAGACACGTCACCAGCTGGGCGGACATCCCGCGTTGGGCGCCACTTCTAGTGCGCCCAGCAATCCATTGCAGTGTATGTTCTGTCGAGCGGTTTGCTCCTCGGAATTGGAGATGCACTTCCACTTGGCGGCCCACGCTCGCCAGTTTAGATGTCCCTCCTGCCCGGAAACCTTCCATGTGGAGTTCCTGCTGGATCGTCACATGCAGAGTCAACATGGTGGGGTAAAGGATAAGGAATCGAACTCACCCAATATGGGAAGTCTCTATGTGAATGCTTTACTGCCTCCTTTGGCGGCGGCGGCGGCGGCAGCAGCGGCCACCAACAACAACAGCAGCATAATAGACTACAATGTGGCGTTCAAGGGATTGTTTGGAGGTTCAGCCGGATCAGGAGGAGGATCTGCAGGAGGGGGAGCAGCAGGAGGAGCTCCACCCTCGAGTAACAAATTCTACAGTCCTCTGCAAGTGGACACCAATGCATTGAAGGCACAAACCTCTCCACATCCTGCTTTAATGTATGGCCTCAGTCAGCGGTATTTGATGGAGATGTATGCTGCCAAATCCACTTCGCCTGCGGGTAACGAAGGAGTGGGGAATCCACCAGTTTCGACTCCCCAGACCGCAGCTCCTCCCCCACAAAGTGCACAAACTGCCACCTTCAGTTGCGGAATGTGCGAGCGACAGGATTTGCGCAGCGAGGCGGAACTCCACTCGCATCGCAAGCTGGCTCACAACTTGAAGACCGGAGTGAGTTTGCGGTGCGCCTACTGTGCGGGCAACTTCAAGTCCCGCGCCGAACTGGAGCAGCACATGAAGAGCTGCCACAACTCGACGGGCAAGCACAAGTGCCTCATCTGCGACGAGGTCTTCCCCTCCCCGGCCATCCTGGCGGAGCACAAGCTGCAGCACTCGAAGGTGGGCCAGTCGGGCAAGTGCTCCCACTGCGGCCAGCCGCTGGAGGATGTGGCCGCCTTCCGAGCTCACCTCTCCGAACATGGAAGCGATGGTGCCTCCCTGCCACTGGCATGCATCTGTTGCCGCCAAACGTTGCACTCGGAATTCGAGCTAAGTCTGCATGCCAAGTTCCACACGAAGTCCTCGTCGAGTGGTGGGAGTCTCCAGGAACCAGTTTGTGCTCTGTGCCTGGAACCTCTGCCCGATGCCACCGAAGGTCCTGCCAAACTGTGCGACAAGTGCTGCCGCAAACACAATCTGAATGGAAAGCGTGGCAAGCCCACTGAACCACCTTCGGCATCTCTGCAGTCGCAGACTCCCTCCTCCTTCGTGGAGAACCGCTGCAATCTGTGCAAGATGATCCTGCCACATGCCCAAAAGCTGCAGGAACACCTGGTGGAACACACTTTCGCTGGCACCGAACAGCGTGGCTTCAATTGCTACATTTGCTCCGCGGTTTTCACCGCTCCTGGAGGATTGCTCAACCACATGGGCGAGCATGGAGCTCACTCTCGTCCCTACGATTGCAGTATTTGCCCGGACAAGTTCTACTTCCGCGCCGAGTTGGAGCACCACCAAAGGAGCCACGAGCAGCGACCCCAAGTGCGTGCTCCTGTGTCCAAAGTGGAGGTGCCCTCCATTCGGAAAAGTTCACCCAGCCAGAGCCCGGTGAGAAGTCCCACGATTGTCAAGCAGGAACTCTACGAAACTGATACGGTTGAATCGAATGCTGGAGAGGATGAGCCCGAGAATCCTCCAGAGGAAGAGGAGTACATCGAAGTGGAGCAGATGCCACATGAGACACGTCCAGCTGAGATTGGGTCGCAAATGGAAAGGTCCACCAGCAGCGCCTAA
Protein Sequence: MSRRKQAKPRACLKLGEKEDEENTGLLEPKEELLSGDEDNEDNEDEDEELADGESAEGGEQQPHPQPQLEPNESQQQSWPTADEPAVPAAVAKEEEDGPEELQHPRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKSSGQDDADADADPEAEAEVEEPEPEDLDLDEELLSLSGDEDYDDEELQSLDSFYSDMYSTHTSSSYSPSISDGTMTPNSHHLPGAPNPAGQEDHHPSEGKANGGAEGEELPKPKRLPHFHHHHHHHYHHQQALKIANKLRKINKETKMGAAAGAGSAGAGSKFDKLTGEGIKSRGDGSYQCQFCEKTFPRLGYLKHHVQSHAEHLPFKCEYCSKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASASVSSNGSLQKRRYALALASDSSPSRLDFPKRSRSGNLGGTTTTTATPTPMLRCSYCPKVTEFSSLEQLNAHLQSVHEQQPTGKSAPGQEGETFQLSCEYCTMKFGNIAGLFQHMRSTHMDRLSSPNSYYEHFNRLATAGTFSPRLALDLPKIKQDLGSPERESRQAEEDLPTDLSSNKRRPLTPNPPSQTQLAPPSAPPGVFFCNQCNAGLPDFESFRNHLKSHIAEGMQLVCPHCGLSLPEQSEFERHVVGHFLITGSEFNCSSSCGKSFAKSEDLQQHLLSDHVLTLLKCSLCSELCESRMAMQLHLACAHSQETKLLRCSACLELFRSDAEFHVHVKTRHQLGGHPALGATSSAPSNPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGVKDKESNSPNMGSLYVNALLPPLAAAAAAAAATNNNSSIIDYNVAFKGLFGGSAGSGGGSAGGGAAGGAPPSSNKFYSPLQVDTNALKAQTSPHPALMYGLSQRYLMEMYAAKSTSPAGNEGVGNPPVSTPQTAAPPPQSAQTATFSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCAGNFKSRAELEQHMKSCHNSTGKHKCLICDEVFPSPAILAEHKLQHSKVGQSGKCSHCGQPLEDVAAFRAHLSEHGSDGASLPLACICCRQTLHSEFELSLHAKFHTKSSSSGGSLQEPVCALCLEPLPDATEGPAKLCDKCCRKHNLNGKRGKPTEPPSASLQSQTPSSFVENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPGGLLNHMGEHGAHSRPYDCSICPDKFYFRAELEHHQRSHEQRPQVRAPVSKVEVPSIRKSSPSQSPVRSPTIVKQELYETDTVESNAGEDEPENPPEEEEYIEVEQMPHETRPAEIGSQMERSTSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00548267;
90% Identity: iTF_00504840;
80% Identity: -