Basic Information

Insect: Drosophila obscura
Gene Symbol: L
Assembly: GCA_018151105.1
Location: NW:7821640-7829283[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 1.2e-05 0.00073 19.6 3.1 1 23 160 182 160 182 0.98

2 18 0.33 20 5.6 6.2 1 23 188 210 188 210 0.97

3 18 1.6e-07 9.8e-06 25.4 3.2 1 23 216 238 216 238 0.99

4 18 1.2e-05 0.00072 19.6 0.4 1 23 244 266 244 266 0.99

5 18 0.021 1.3 9.3 0.2 2 23 342 366 341 366 0.92

6 18 0.0036 0.22 11.7 0.2 2 23 400 422 399 422 0.95

7 18 0.059 3.6 7.9 0.7 1 23 507 529 507 529 0.97

8 18 0.0043 0.27 11.5 0.1 2 23 537 558 536 558 0.91

9 18 0.00025 0.015 15.4 0.1 1 23 566 590 566 590 0.95

10 18 3.5 2.1e+02 2.4 0.1 2 20 596 614 595 615 0.92

11 18 1.2 76 3.8 0.9 2 23 626 648 625 648 0.95

12 18 0.0024 0.15 12.3 1.1 1 23 703 726 703 726 0.97

13 18 0.0047 0.29 11.4 1.2 2 23 924 946 923 946 0.96

14 18 0.11 6.7 7.1 0.1 1 23 952 974 952 974 0.92

15 18 2.4 1.5e+02 2.9 0.6 2 23 982 1003 982 1003 0.95

16 18 0.7 43 4.5 0.5 2 23 1103 1124 1103 1124 0.94

17 18 0.067 4.1 7.8 0.0 1 23 1134 1156 1134 1156 0.96

18 18 6.3e-05 0.0039 17.3 1.0 1 23 1163 1185 1163 1185 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	1.2e-05	0.00073	19.6	3.1	1	23	160	182	160	182	0.98
2	18	0.33	20	5.6	6.2	1	23	188	210	188	210	0.97
3	18	1.6e-07	9.8e-06	25.4	3.2	1	23	216	238	216	238	0.99
4	18	1.2e-05	0.00072	19.6	0.4	1	23	244	266	244	266	0.99
5	18	0.021	1.3	9.3	0.2	2	23	342	366	341	366	0.92
6	18	0.0036	0.22	11.7	0.2	2	23	400	422	399	422	0.95
7	18	0.059	3.6	7.9	0.7	1	23	507	529	507	529	0.97
8	18	0.0043	0.27	11.5	0.1	2	23	537	558	536	558	0.91
9	18	0.00025	0.015	15.4	0.1	1	23	566	590	566	590	0.95
10	18	3.5	2.1e+02	2.4	0.1	2	20	596	614	595	615	0.92
11	18	1.2	76	3.8	0.9	2	23	626	648	625	648	0.95
12	18	0.0024	0.15	12.3	1.1	1	23	703	726	703	726	0.97
13	18	0.0047	0.29	11.4	1.2	2	23	924	946	923	946	0.96
14	18	0.11	6.7	7.1	0.1	1	23	952	974	952	974	0.92
15	18	2.4	1.5e+02	2.9	0.6	2	23	982	1003	982	1003	0.95
16	18	0.7	43	4.5	0.5	2	23	1103	1124	1103	1124	0.94
17	18	0.067	4.1	7.8	0.0	1	23	1134	1156	1134	1156	0.96
18	18	6.3e-05	0.0039	17.3	1.0	1	23	1163	1185	1163	1185	0.97

Sequence Information

Coding Sequence: ATGATGGCCCTAAAAATGCTTTATCGCGGCCCCAGCTCGCGTTTGGAGAATCTCATTGAGAAGATCCAGGCCACCAAGGAGATCACAAATAACGACATGTACAGTACCCACACCTCGTCCAGCTACTCGCCGAGCATCTCCGATGGGACCATGACACCCAACGCCCATCATCTGGCCACTGCCTCGACGAATGCCCTGCAGGAGGAGCTCCATCCGGGTGACGGCAAGTCGAACGGTGTCCCAGGAGAGGAGTCTGCGAAGCCAAAGCGACAGCCGCActtccaccaccaccaccatcactACCATCACCAGCAGGCCCTGAAGATTGCCAACAAGCTGCGCAAAATCAATAAGGAGGCCAAAATggcagctgcaggagcagcaggagctggatCCGGATCCGGCGCTGCTGGCGGAGCAGCCGCAAAGTTTGATAAGTTGACAGGCGAAGGCATTAAGAGTCGCGGCGACGGCTCCTATCAGTGCCAGTTCTGTGATAAGACGTTTCCGCGTCTCGGCTACTTGAAGCATCACGTGCAGAGCCATGCCGAGCATCTGCCCTTCAAGTGCGAGTACTGCGCCAAGCTGTTCAAGCACAAACGCTCCCGGGATCGCCATAAGAAGCTGCACACCAACGAGCGCAACTACAAGTGTCCGCACTGCGAGGCGGCCTTCTCCCGAAGCGATCACCTGAAGATCCACATGAAGACGCATGACATCCAGAAGCCGTTCCAGTGCAGCATGTGCAACAGGGGCTACAACACGGCCGCGGCCCTCACCTCGCACATGCAGAAGCACAAGAAGAACGCCGCCATACTGGCAGCCGGCGGCAATCCCAATGCCCTCAACTACAGTCCCCGGTCCACGGGCTCCGCCTCGGCGTCGGTGTCCAGCAATGGGAGCCTGCACAAGCGGCGCTatgccctggccctggccaccGACAGCAGTTCCAGTCGCCTGGACTTTCCCAAGAGATCGCGCAGCAGCCATGTGGCCGGCACGCCAACACCCACCCCGCTGCTGCGATGCAGCTACTGCCCCAAGGCGACGGAGTTCAGCAGCTTGGAGCAGCTGAATGCCCATCTCCAGAATGtccacgagcagcagcagcagcagcaacagccacagcagcagtcacagcagcagcagcagcaatcggcGAAGACTCCCGTCCAGGAGGGGGAGGGCTTCCAGCTGAGCTGCGAGTACTGCACCATGAAGTTTGGAAACATTGCCGGACTCTTCCAGCACATGCGCGCCACCCATCTGGATCGCCTGAGCAGCCCCAACTCCTACTACGAGCACTTCAACCGGCTGGCCACCGCAGGAACATTTAGTCCACGGCTGGCGCTGGATCTGCCCAAGATAAAGCCGGATCTGGGCAGTCCCGAGCCGCGGGAGAGCCGACCCTCCGAGGACGACCTGCCCACGGATCTGAGCAGCAACAAGCGTCGACCGCAGACACCAGCCAACGCAGCGCCCAATCCTCCGCCGCAGGCAGCGGCACCCCCCGGCATCTTCTTCTGCAACCAGTGCAACGCGGGACTACCCGACTTCGAGAGCTTCCGCAATCACCTGAAGAGCCACATTGCCGAGGGAATGCAGCTGATCTGCCCCCACTGTGGGCTGAGTCTGCCGGAGCAGTCGGACTTTGAGCGTCACGTGGTGGGACACTTCCTGATCGCCAACTCCGAGTTCAACTGCAGCGCCAGCTGCGGCAAGAGCTTCGGCAAGgcggaggagctgcagcagcacctcaTCACCGAGCACGTGCTCACCCTGCTGAAGTGCGGCCTCTGCTCGGAGATGTGCGAGACGCGGATGGCCATGCAGCTGCATCTGGCCTGCGCCCACAGCCACGAGACGAAGCTGCTGCGCTGCAGCGCCTGCATGGAGGTCTTCCGCTCCGATGGCGACTTCCATGTGCACGTAAAGACGCGCCATCAGCTGGGCAACcatcaccagcaccagcagcaccaccaacagCACCACCCGATGGGCGGCAACGGCGGCAGTCCGGCCAACCCGCTGCAGTGCATGTTCTGCCGGGCCGTGTGCTCCTCCGAGCTGGAGATGCACTTCCATCTGGCGGCGCATGCGCGACAGTTTCGCTGTCCCTCCTGTCCGGAGACCTTCCACGTGGAGTTCCTGCTGGACAGGCACATGCAGAGCCAGCACGGCGGCGGCAAGGACAAGGAGCAGCCGCCCCAAAGCTCCCCCAACATGGGCAGTCTCTATGTGAACGCCCTGCTGCCGCCCCTGgccgcagctgccgctgccgcagccgccaccaacaacaacagcagcatcatcgaCTACAACGTGGCCTTCAAGGGTCTGTTCGGTGGGGGAGCGACCGGAGGCAGTGCACCCACGGGCCCCGCGGCGGCCAGCAAGTTCTACAGCCCCTTGCAGGTGGACACGAATGCCCTGAAGGCACAGACCTCGCCCCATCCCGCCCTGATGTACGGCCTCAGCCAGCGCTACCTGATGGAGATGTACGCCGCCAAGTCCACGTCTCCGGCCAACAGCACCGCCAacgaatcagcagcagcagcagcagcagccggaggaggaggagtaggagtaggagtaggaatTGGAGGAGCCTCCTCCATCAATGGCCCGCCAGCAGCACAGGCGCCGCCGCCAAGCGCACCCGCTGCCACCTTCAGCTGTGGGATGTGCGAGCGCCAGGATCTGCGCAGCGAGGCGGAACTCCACTCGCACCGGAAGCTGGCCCACAACCTGAAGACTGGCGTGAGCCTGCGCTGCGCCTACTGTGCGGGCAACTTCAAGTCGCGGgcggagctggagcagcacaTGAAGAGCTGCCACAACTCGACGGGCAAGCACAAGTGCCTCATCTGCGACGAGATCTTCCCCTCGCCGGCCATCCTGGCGGAGCACAAGCTGCAGCACTCGAAGGTGGGCCAGTCGGGCAAGTGCGCCCACTGCAGCCACCCGTTGGAGGATGTGGCCGCCTTCCGGGCCCATCTCAGCGAGCATGGCAGCGATGGCGCCTCCCTGCCCCTGGCCTGCATTTGCTGTCGCCAGACGCTCCACTCGGAGTTCGAGCTGAGCCTGCACGCCAAGTTCCACACCAAGTCCTCGTCCAGTGGCGGCAGTCTCCAGGAGCCGGTTTGCGCCCTCTGCCTGGAGCCGCTGCCAGGGGCAGTGGAGGGTCCCACCACGCCGGCCAAGCTGTGCGAGAAGTGCTGCCGCAAGCACAACCTCAACGGCAAGCGGAGCAAGGCCAGCGAGGGCCCCGCGATCCAGGCCCAGCCGGCTGCCTACCTGGAGAACCGCTGCAATCTGTGCAAGATGATCCTGCCGCACGCCCAGAAGCTGCAGGAGCACCTGGTGGAGCACACCTTCGCCGGCACCGAGCAGCGCGGCTTCAATTGCTACATCTGCTCGGCCGTCTTCACGGCCCCCGGCGGCCTCCTTGGCCACATGGCCGAGCACGGGGCCCACTCGCGTCCCTACGACTGCAACATCTGCCCCGAGAAGTTCTACTTCCGCGCCGAGCTGGAGCACCACCAGCGCGCCCACGAGCTGAGGCCAACGGTTCGTCCAGCGCTGGCCAAGCCAGAGCCACCGATGCGACGCAGTGCTTCGCCCAGTCCGAGTCCAGTGCGAAGTCCCACGACCGTCAAGCAGGAGCTGTACGACACGGATACGGGCCACTCCGGCGGCTGTGATGATGAGCCAGAGCCCGCCCAGGACGAGGAGGAGTACATAGAGGTGGAGCGGATGCCGCACGAGACGCGGCCAAGGGATGTCATGTCACAGCTGGAAAGGGCCACAAACAGCGCCTGA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEITNNDMYSTHTSSSYSPSISDGTMTPNAHHLATASTNALQEELHPGDGKSNGVPGEESAKPKRQPHFHHHHHHYHHQQALKIANKLRKINKEAKMAAAGAAGAGSGSGAAGGAAAKFDKLTGEGIKSRGDGSYQCQFCDKTFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASASVSSNGSLHKRRYALALATDSSSSRLDFPKRSRSSHVAGTPTPTPLLRCSYCPKATEFSSLEQLNAHLQNVHEQQQQQQQPQQQSQQQQQQSAKTPVQEGEGFQLSCEYCTMKFGNIAGLFQHMRATHLDRLSSPNSYYEHFNRLATAGTFSPRLALDLPKIKPDLGSPEPRESRPSEDDLPTDLSSNKRRPQTPANAAPNPPPQAAAPPGIFFCNQCNAGLPDFESFRNHLKSHIAEGMQLICPHCGLSLPEQSDFERHVVGHFLIANSEFNCSASCGKSFGKAEELQQHLITEHVLTLLKCGLCSEMCETRMAMQLHLACAHSHETKLLRCSACMEVFRSDGDFHVHVKTRHQLGNHHQHQQHHQQHHPMGGNGGSPANPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGGKDKEQPPQSSPNMGSLYVNALLPPLAAAAAAAAATNNNSSIIDYNVAFKGLFGGGATGGSAPTGPAAASKFYSPLQVDTNALKAQTSPHPALMYGLSQRYLMEMYAAKSTSPANSTANESAAAAAAAGGGGVGVGVGIGGASSINGPPAAQAPPPSAPAATFSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCAGNFKSRAELEQHMKSCHNSTGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCSHPLEDVAAFRAHLSEHGSDGASLPLACICCRQTLHSEFELSLHAKFHTKSSSSGGSLQEPVCALCLEPLPGAVEGPTTPAKLCEKCCRKHNLNGKRSKASEGPAIQAQPAAYLENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPGGLLGHMAEHGAHSRPYDCNICPEKFYFRAELEHHQRAHELRPTVRPALAKPEPPMRRSASPSPSPVRSPTTVKQELYDTDTGHSGGCDDEPEPAQDEEEYIEVERMPHETRPRDVMSQLERATNSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00548267;
90% Identity: iTF_00611560;
80% Identity: -