Basic Information

Insect: Drosophila biarmipes
Gene Symbol: L
Assembly: GCA_018148935.1
Location: JAECYG010000260.1:3879542-3886164[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 4.2e-05 0.0025 17.9 3.0 1 23 152 174 152 174 0.98

2 17 0.15 9 6.7 7.3 1 23 180 202 180 202 0.97

3 17 1.7e-07 9.9e-06 25.5 3.2 1 23 208 230 208 230 0.99

4 17 1.2e-05 0.00073 19.6 0.4 1 23 236 258 236 258 0.99

5 17 0.012 0.71 10.2 0.2 2 23 338 362 337 362 0.92

6 17 0.0038 0.23 11.8 0.2 2 23 385 407 384 407 0.95

7 17 0.061 3.6 8.0 0.7 1 23 492 514 492 514 0.97

8 17 0.0041 0.25 11.7 0.1 2 23 522 543 521 543 0.92

9 17 9.2e-05 0.0055 16.9 0.4 1 23 551 575 551 575 0.94

10 17 4.9 2.9e+02 2.0 0.9 2 23 611 633 610 633 0.94

11 17 0.0025 0.15 12.4 1.1 1 23 678 701 678 701 0.97

12 17 0.0049 0.29 11.4 1.2 2 23 884 906 883 906 0.96

13 17 0.039 2.4 8.6 0.1 1 23 912 934 912 934 0.92

14 17 0.074 4.4 7.7 0.2 2 23 942 963 941 963 0.96

15 17 0.73 43 4.6 0.5 2 23 1061 1082 1061 1082 0.94

16 17 0.019 1.2 9.5 0.0 1 23 1092 1114 1092 1114 0.95

17 17 0.00033 0.02 15.1 1.2 1 23 1121 1143 1121 1143 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	4.2e-05	0.0025	17.9	3.0	1	23	152	174	152	174	0.98
2	17	0.15	9	6.7	7.3	1	23	180	202	180	202	0.97
3	17	1.7e-07	9.9e-06	25.5	3.2	1	23	208	230	208	230	0.99
4	17	1.2e-05	0.00073	19.6	0.4	1	23	236	258	236	258	0.99
5	17	0.012	0.71	10.2	0.2	2	23	338	362	337	362	0.92
6	17	0.0038	0.23	11.8	0.2	2	23	385	407	384	407	0.95
7	17	0.061	3.6	8.0	0.7	1	23	492	514	492	514	0.97
8	17	0.0041	0.25	11.7	0.1	2	23	522	543	521	543	0.92
9	17	9.2e-05	0.0055	16.9	0.4	1	23	551	575	551	575	0.94
10	17	4.9	2.9e+02	2.0	0.9	2	23	611	633	610	633	0.94
11	17	0.0025	0.15	12.4	1.1	1	23	678	701	678	701	0.97
12	17	0.0049	0.29	11.4	1.2	2	23	884	906	883	906	0.96
13	17	0.039	2.4	8.6	0.1	1	23	912	934	912	934	0.92
14	17	0.074	4.4	7.7	0.2	2	23	942	963	941	963	0.96
15	17	0.73	43	4.6	0.5	2	23	1061	1082	1061	1082	0.94
16	17	0.019	1.2	9.5	0.0	1	23	1092	1114	1092	1114	0.95
17	17	0.00033	0.02	15.1	1.2	1	23	1121	1143	1121	1143	0.97

Sequence Information

Coding Sequence: ATGATGGCCCTAAAGATGTTATATCGCGGTCCCAGTTCGCGTTTGGAGAATTTAATTGAAAAGATCCAGGCCACCAAGGAGATAACCAACAACGATATGTACAGTACCCACACATCGTCCAGCTATTCGCCTAGTATTTCTGACGGCACTATGACTCCGAATTCACACCACTTGCCGGGAGCCCTTGCGGCCGCTGGTCACGAGGATCATCCAGCCGAGGGCAAGGTCAATGGTGGTCCTGAAGGCGGGGATTTGCCCAAGCCAAAACGCCTGCCGCACTTCCATCACCACCATCACTATCATCATCAACAGGCGCTGAAAATAGCCAACAAGCTGCGCAAAATCAATAAGGAAGCCAAAATGGGAGCTAACGGAGGTGCGGGCTCCGCTGGAGCAGTCTCCAAGTTTGATAAGTTGACAGGAGAGGGGATTAAAAGTCGCGGCGACGGCTCCTATCAGTGCCAGTTTTGCGAGAAGACATTTCCACGGCTCGGCTATTTAAAGCATCACGTACAGAGCCACGCCGAACACCTGCCTTTCAAGTGCGAGTACTGCTCCAAGCTTTTCAAGCACAAGCGTTCCCGAGATCGCCATAAGAAATTGCATACCAACGAGAGGAACTACAAGTGTCCGCATTGCGAGGCAGCTTTTTCCAGAAGTGACCACTTGAAGATCCACATGAAGACCCATGACATCCAGAAGCCCTTCCAGTGCAGCATGTGCAACAGGGGCTATAACACAGCCGCTGCTCTAACCTCGCACATGCAGAAGCACAAGAAGAATGCCGCCATCCTGGCAGCTGGAGGTAATCCCAATGCCCTGAACTACAGTCCAAGATCAACGGGATCTGCCTCGGCTTCGGTATCCAGCAATGGTAGTCTGCAGAAGAGGCGATATGCCTTGGCCCTGGCCTCGGATAGCAGTCCCAGTCGTTTGGATTTCCCCAAGAGATCCAGAAGTGGTCATGTGGGTGGTGGCACCACCACCACGGCCACGCCCACTCCCCTGCTGAGGTGCAGCTACTGCCCCAAGGTCACAGAGTTCAGTAGTCTGGAGCAACTGAATGCCCATCTCCAGAGTGTCCACGAGCAGCAGCCACAGCAACAGGGGACGGCGAAGACTCCCGTACAGGAGGGCGAGGGATTCCAGCTGAGCTGCGAGTACTGCACCATGAAGTTTGGCAACATCGCCGGACTCTTCCAGCACATGAGGGGCACCCACATGGACCGATTGAGCAGCCCCAACTCCTATTACGAGCACTTCAATCGCCTGGCCACCGCTGGCACCTTCAGTCCGCGATTGGCCCTGGATTTACCCAAAATAAAACCGGATTTGGGAAGTCCGGAGAGGGAATCGCGACCTGCGGAGGAGGAGCTTCCAACGGATTTGAGCAGCAACAAGAGGAGACCACTGACACCGAGTCCCCAGACCCAGCAGTCTCAATTGGCGCCACCTTCTGCTCCACCTGGGGTCTTCTTCTGCAATCAGTGCAACGCTGGTCTGCCGGATTTCGAGAGCTTCAGGAATCATCTGAAGAGCCACATTGCCGAGGGCATGCAGATGGTTTGTCCACATTGCGGCCTGAGTTTGCCGGAGCAATCGGAGTTCGAGCGTCATGTGGTAGGTCACTTCCTCATCACCGGATCGGAGTTCAACTGCAGTTCTAGCTGCGGCAAGAGCTTCGCCAAGTCGGAGGATCTGCAGCAACATTTGCTGTCGGAGCACGTGCTAACCCTGCTGAAGTGCTCCTTGTGCTCAGAGCTGTGTGAGAGCCGGATGGCCATGCAGCTGCACTTGGCCTGTGCCCACAGTCAGGAGACGAAGCTTCTCCGTTGCAGCGCCTGCTTGGAGCTCTTTCGATCCGATGCCGAGTTTCACGTCCATGTGAAGACGCGTCATCAGCTGGGCGGACATCCCACGTTGGGCGCCACCTCTTCTGCACCCAGTAATCCGCTGCAGTGCATGTTCTGTCGAGTAGTCTGCTCCTCGGAGCTGGAGATGCACTTTCACCTGGCCGCCCATGCACGTCAGTTCAGGTGTCCCTCCTGCCCGGAGACCTTCCATGTGGAATTCCTGTTGGATCGCCACATGCAGAGTCAGCATGGCGGAGTCAAGGACAAGGAGTCGAACTCACCCAATATGGGTAGTCTCTATGTGAATGCCTTGCTGCCTCCTTTGGCTGCAGCGGCGGCGGCAGCAGCGGCCACCAATAACAACAGCAGTATCATCGACTACAATGTGGCATTCAAGGGTTTGTTCGGAGGAGGAGCAGGTGGAGCTGGATCAGGTGGTGGAGGAGGAGCAGCTGGAGGAGCACCGCCTTCGGGCAACAAATTCTACAGCCCTCTTCAGGTGGACACCAATGCTCTGAAGGCCCAAACCTCCCCCCATCCGGCCTTAATGTACGGTCTGAGTCAGCGGTATCTAATGGAGATGTATGCCGCCAAGTCCACATCGCCCGCGGGCAATGAGGGAGTTGGAAACCCGCAGCCGCCGGCTCCTCAGGCCACCGCACCACCACCACCGCCACCGAGTTCTGCGACTGCCACCTTCAGTTGCGGAATGTGCGAGCGGCAAGATTTGCGCAGCGAGGCGGAACTCCACTCCCACCGCAAGCTGGCCCACAATCTGAAGACGGGAGTGAGCCTGCGGTGTGCCTACTGCGCTGGCAACTTCAAGTCCCGGGCCGAGCTGGAGCAGCACATGAAGAGCTGCCACAACTCGACGGGCAAGCACAAGTGCTTGATATGCGACGAGGTGTTTCCCTCACCGGCCATCCTGGCCGAACACAAGCTCCAGCACTCGAAGGTGGGGCAGTCGGGCAAGTGCTCCCACTGCGGTCAGCAGCTGGAGGATGTGGCCGCCTTCAGGGCTCATCTGTCCGAGCATGGCAGCGATGGTGCCTCCCTGCCACTGGCCTGCATCTGCTGCCGCCAGACCTTGCACTCGGAATTCGAGCTAAGTCTGCATGCCAAATTCCACACGAAGTCCTCCTCGAGCGGTGGAAGTCTGCAGGAACCAGTGTGTGCCCTGTGCCTGGAGCCCCTACCCGATGCCACCGAAGGACCAGCAAAGCTGTGCGACAAGTGCTGTCGCAAACACAATCTGAATGGCAAACGGGGCAAGCCCACTGATCCGCCGGCATCGCTGCAACCGCCAGTCTCCTCCTTTGTGGAGAACCGCTGCAACCTGTGCAAGATGATCCTGCCACATGCCCAGAAGCTGCAGGAGCACCTGGTGGAGCACACCTTCGCGGGCACCGAACAGCGTGGCTTCAACTGCTACATTTGCTCGGCTGTTTTCACCGCTCCCGGCGGACTACTCAACCACATGGGCGAACATGGCGCCCATTCGCGACCCTACGACTGCAGCCTCTGCCCGGAGAAGTTCTACTTCCGTGCCGAGTTGGAGCACCACCAGAGGGGCCATGAGCAGAGGCCACAGGCACGTCCTTCCGTGTCCAAGGCAGAGGCTCCCGCCAAGCGGAACACTTCACCCAGCCAGAGTCCGGTGAGAAGTCCCACGGTTGTCAAGCAGGAGCTATACGAAACGGACACAGTTGAGTCCGCCGGAGCGGAGGATGAGCAGCAGAATGCCCCGGATGAGGAGGAGTACATTGAAGTGGAACAAATGCCGCATGAGACACGTCCAAGTGAGATTGGGTCGCAATTGGAAAGGTCCACCAGTAGCGCCTAA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEITNNDMYSTHTSSSYSPSISDGTMTPNSHHLPGALAAAGHEDHPAEGKVNGGPEGGDLPKPKRLPHFHHHHHYHHQQALKIANKLRKINKEAKMGANGGAGSAGAVSKFDKLTGEGIKSRGDGSYQCQFCEKTFPRLGYLKHHVQSHAEHLPFKCEYCSKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASASVSSNGSLQKRRYALALASDSSPSRLDFPKRSRSGHVGGGTTTTATPTPLLRCSYCPKVTEFSSLEQLNAHLQSVHEQQPQQQGTAKTPVQEGEGFQLSCEYCTMKFGNIAGLFQHMRGTHMDRLSSPNSYYEHFNRLATAGTFSPRLALDLPKIKPDLGSPERESRPAEEELPTDLSSNKRRPLTPSPQTQQSQLAPPSAPPGVFFCNQCNAGLPDFESFRNHLKSHIAEGMQMVCPHCGLSLPEQSEFERHVVGHFLITGSEFNCSSSCGKSFAKSEDLQQHLLSEHVLTLLKCSLCSELCESRMAMQLHLACAHSQETKLLRCSACLELFRSDAEFHVHVKTRHQLGGHPTLGATSSAPSNPLQCMFCRVVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGVKDKESNSPNMGSLYVNALLPPLAAAAAAAAATNNNSSIIDYNVAFKGLFGGGAGGAGSGGGGGAAGGAPPSGNKFYSPLQVDTNALKAQTSPHPALMYGLSQRYLMEMYAAKSTSPAGNEGVGNPQPPAPQATAPPPPPPSSATATFSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCAGNFKSRAELEQHMKSCHNSTGKHKCLICDEVFPSPAILAEHKLQHSKVGQSGKCSHCGQQLEDVAAFRAHLSEHGSDGASLPLACICCRQTLHSEFELSLHAKFHTKSSSSGGSLQEPVCALCLEPLPDATEGPAKLCDKCCRKHNLNGKRGKPTDPPASLQPPVSSFVENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPGGLLNHMGEHGAHSRPYDCSLCPEKFYFRAELEHHQRGHEQRPQARPSVSKAEAPAKRNTSPSQSPVRSPTVVKQELYETDTVESAGAEDEQQNAPDEEEYIEVEQMPHETRPSEIGSQLERSTSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00548267;
90% Identity: iTF_00504840;
80% Identity: -