Basic Information

Insect: Drosophila seguyi
Gene Symbol: L
Assembly: GCA_008042675.1
Location: VNJU01008754.1:180436-187661[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 9.4e-06 0.00069 19.9 2.9 1 23 159 181 159 181 0.98

2 17 0.14 10 6.7 7.3 1 23 187 209 187 209 0.97

3 17 1.6e-07 1.1e-05 25.5 3.2 1 23 215 237 215 237 0.99

4 17 1.2e-05 0.00084 19.6 0.4 1 23 243 265 243 265 0.99

5 17 0.018 1.3 9.5 0.2 2 23 350 374 349 374 0.93

6 17 0.0025 0.18 12.2 0.4 2 23 396 418 395 418 0.95

7 17 0.057 4.2 7.9 0.7 1 23 506 528 506 528 0.97

8 17 0.0039 0.28 11.6 0.1 2 23 536 557 535 557 0.92

9 17 8.6e-05 0.0063 16.8 0.4 1 23 565 589 565 589 0.94

10 17 4.6 3.4e+02 1.9 0.9 2 23 625 647 624 647 0.94

11 17 0.0023 0.17 12.3 1.1 1 23 693 716 693 716 0.97

12 17 0.0046 0.33 11.4 1.2 2 23 905 927 904 927 0.96

13 17 0.037 2.7 8.5 0.1 1 23 933 955 933 955 0.92

14 17 0.045 3.3 8.3 0.1 2 23 963 984 962 984 0.96

15 17 0.69 50 4.6 0.5 2 23 1089 1110 1089 1110 0.94

16 17 0.0089 0.65 10.5 0.0 1 23 1120 1142 1120 1142 0.96

17 17 0.00016 0.012 16.0 1.7 1 23 1149 1171 1149 1171 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	9.4e-06	0.00069	19.9	2.9	1	23	159	181	159	181	0.98
2	17	0.14	10	6.7	7.3	1	23	187	209	187	209	0.97
3	17	1.6e-07	1.1e-05	25.5	3.2	1	23	215	237	215	237	0.99
4	17	1.2e-05	0.00084	19.6	0.4	1	23	243	265	243	265	0.99
5	17	0.018	1.3	9.5	0.2	2	23	350	374	349	374	0.93
6	17	0.0025	0.18	12.2	0.4	2	23	396	418	395	418	0.95
7	17	0.057	4.2	7.9	0.7	1	23	506	528	506	528	0.97
8	17	0.0039	0.28	11.6	0.1	2	23	536	557	535	557	0.92
9	17	8.6e-05	0.0063	16.8	0.4	1	23	565	589	565	589	0.94
10	17	4.6	3.4e+02	1.9	0.9	2	23	625	647	624	647	0.94
11	17	0.0023	0.17	12.3	1.1	1	23	693	716	693	716	0.97
12	17	0.0046	0.33	11.4	1.2	2	23	905	927	904	927	0.96
13	17	0.037	2.7	8.5	0.1	1	23	933	955	933	955	0.92
14	17	0.045	3.3	8.3	0.1	2	23	963	984	962	984	0.96
15	17	0.69	50	4.6	0.5	2	23	1089	1110	1089	1110	0.94
16	17	0.0089	0.65	10.5	0.0	1	23	1120	1142	1120	1142	0.96
17	17	0.00016	0.012	16.0	1.7	1	23	1149	1171	1149	1171	0.98

Sequence Information

Coding Sequence: ATGATGGCCCTAAAGATGTTATATCGCGGTCCCAGTTCGCGTTTggagaatttaattgaaaagatCCAGGCCACCAAGGAGATAACCAATAGCGACATGTACAGTACCCACACATCGTCCAGTTACTCGCCTAGCATTTCGGATGGCACCATGACGCCCAATTCCCACCATTTGCCCGGAGCTCCAACCTCTGTGGCCGCCTCTGGCCAGGAGGATCATCATCATTCCACCGATGGCAAACTGAATGGCGGTACCGATGGCGAGGAGCTGGCCAAACCGAAACGCTTGCCACACttccatcaccatcaccaccatcaCTACCACCATCAGCAGGCGCTGAAAATCGCCAACAAGCTGCGCAAAATCAATAAGGAAGCCAAAATGGGAGCTGGCGGCGGTGCTGGTGCCGGAGGAGCAGGCTCCAAGTTTGATAAGTTGACAGGCGAGGGGATTAAGGCTCGCGGCGACGGCTCCTATCAGTGTCAGTTCTGCGATAAGTCATTTCCGCGTCTCGGCTACTTGAAGCATCACGTGCAGAGCCACGCCGAACACCTGCCCTTCAAGTGCGAATACTGCTCGAAGCTGTTCAAGCACAAGCGGTCCCGGGATCGCCACAAGAAGCTGCATACCAACGAGCGCAACTACAAGTGTCCCCATTGCGAGGCGGCCTTCTCCAGGAGTGACCACCTGAAGATCCACATGAAGACGCACGACATCCAGAAGCCGTTCCAGTGCAGCATGTGCAACCGGGGCTATAACACGGCGGCCGCCCTGACCTCGCACATGCAGAAGCACAAGAAGAATGCGGCCATCCTGGCCGCTGGGGGCAATCCCAATGCCCTGAACTACAGTCCCCGCTCTACGGGATCGGCCTCGGCCTCGGTCTCGAGCAATGGCAGTCTGCAGAAGAGGCGGTATGCCCTGGCTCTAGCTTCCGATAGCAGTCCCAGCAGGCTGGATTTCCCCAAGAGATCCAGGAGCAGTCATGTGGCTGGTAATGGAGGCGgaggcaccaccaccacgacgGCCACACCCACGCCCCTGCTCAGGTGCAGCTACTGCCCGAAGGCCACCGAGTTTAGCAGCTTGGAGCAGCTGAATGTCCACCTGCAGAGTGTCcacgagcagcagcatcagcatgcGGCCAAGCCGCCGGTGGCGCCGGAGAGCGAGGGCTTCCAGCTGAGCTGCGAGTATTGCACCATGAAGTTCGGCAATATAGCAGGCCTCTTCCAGCACATGAGGAACACTCACCTGGACAGATTGAGCAGCCCGAACTCCTACTACGAGCACTTCAATCGCCTGGCCACCGCTGGCACCTTCAGTCCGCGTCTGGCCCTGGAATTGCCTAAAATCAAGCCGGACTTGGGCAGCCCGGAGAGGGAGAGCACGCGAGCCGCCGAGGAGGATCTGCCCACGGACTTGAGCAGCAACAAGCGGCGATCCCAGACACCCACGAATGCCCAGCAAGTGCAGTCCCAGCAGCTGGCACCACCAGCCGCTCCTCCCGGAGTGTTCTTCTGCAATCAGTGCAACGCCGGCCTGCCGGACTTTGAGAGCTTCAGGAATCACCTGAAGAGCCACATCGCCGAGGGCATGCAGATGGTGTGTCCCCACTGCGGACTGAGCCTGCCGGAGCAGTCGGAGTTCGAGCGCCATGTGGTGGGCCACTTCCTCATCACCGGCTCCGAGTTCAactgcagctccagctgcgGCAAGAGCTTCGCCAAGTCGGAGGACCTGCAGCAGCACCTGCTGTCCGAGCACGTGCTCACCCTGCTGAAGTGCTCGCTGTGCTCGGAGCTCTGCGAGAGCCGGATGGCCATGCAGCTGCACCTGGCCTGTGCCCACAGCCAGGAGACGAAGCTGCTGCGCTGCAGCGCCTGCCTGGAGCTCTTCCGCTCCGATGCCGAGTTCCATGTGCATGTGAAGACGCGCCACCAGCTGGGGGGCGGACATCCTGCGCTGGGCGCCACCCCGAGCGCTCCTGCCAATCCCCTGCAGTGCATGTTCTGCCGGGCAGTCTGCTCCTCGGAGCTGGAGATGCACTTCCATCTGGCGGCGCATGCCAGGCAGTTCCGGTGCCCCTCCTGCCCGGAGACCTTCCACGTGGAGTTCCTGCTGGACAGGCACATGCAGAGCCAGCACGGCGGCGGCGTCAAggacaaggagcagcagcggggCTCGCCCAACATGGGCAGtctctatgtgaatgccctgCTGCCTCCcctggcggcagcggcggcggcagcagcggccaccaacaacaacagcagcaccatcgACTACAATGTGGCTTTCAAGGGTCTGTTTGGAGGCGGAGCAGGAGGGGGATCAGCCTCTGGAGCGGGATCGGGCGCTGGAGGAGGCTCTGGGACAGCCCCGCCCTCGGGCAACAAGTTCTACAGTCCCCTGCAGGTGGACACCAATGCCTTGAAGGCTCAGACCTCACCGCATCCCGCCCTCATGTACGGCCTGAGTCAGCGCTATCTGATGGAGATGTACGCCGCCAAGTCCACCTCACCGGCGGGCGGCAACGAGGGCAATCCGCAGCCACCGCAGGCCACTGCTCCGCCGAGTGCTCCACCGAGTGCCGCTCCAGCCGCTGCCACCTTCAGCTGTGGCATGTGCGAGCGCCAGGATCTGCGCAGCGAGGCGGAGCTCCACTCGCACCGCAAGCTGGCGCACAACCTCAAGACGGGCGTGAGTCTAAGGTGCGCCTACTGTGCCGGGAACTTCAAGTCCCGggcggagctggagcagcacaTGAAGAGCTGCCACAATTCGACGGGCAAGCACAAGTGCCTGATCTGCGACGAGGTCTTCCCCTCGCCGGCCATCCTGGCCGAGCACAAGCTGCAGCACTCGAAGGTGGGACAGTCGGGCAAGTGCTCGCACTGCGGCCAGCCGCTGGAGGATGTGGCCGCCTTCCGGGCCCACCTCTCGGAGCATGGCAGCGACGGGGCCACCCTGCCGCTGGCCTGCATCTGCTGTCGCCAGACGCTGCACTCGGAGTTCGAGCTGAGCCTGCATGCCAAGTTCCACACCAAGTCGGCCTCGAGTGGGGGCAGCCTCCAGGAGCCGGTGTGTGCTCTGTGCCTGGAGCCACTGCCCGATGTGCCAGTCGAGGGTCCGGCCAAGCTGTGCGAGAAGTGCTGTCGGAAGCACAACCTCAATGGCAAGCGCGGAAAGCCAAGTGACCAGCCGCTGCAGGCCCCTCCATcctcagcaggagcaggatcagGAGCTGCCTTCGTGGAGAACCGCTGCAACCTGTGCAAGATGATCCTGCCGCATGCCCAGAAGCTCCAGGAACACCTGGTGGAGCACACCTTTGCGGGCACCGAGCAGCGCGGCTTCAACTGCTACATCTGCTCGGCGGTATTCACGGCTCCGGGAGGCTTGCTCAATCACATGGCAGAGCACGGAGCCCATTCGCGTCCCTACGACTGCAGCCTGTGTCCGGAGAAGTTCTACTTCCGGGCGGAGCTGGAGCACCATCAGAGGAGTCACGAGCTGCGGCCACAGGCCTCGAGGCCTCCACCCATGCCCAAGGTGGAGGCACCCTCCATCAGGAATAGTTCACCCATATGCGAGAGTCCTCCGTCCAGGAGTCGCAGTCCCACGATCAATGTCAAGCAGGAACTCTACGAAACGGACACCGTGGAGTCGGGAGCAGGAGAAGATGAGCCAGAGGAGAATCCCCAAGAGGATGAGGAGTACATTGAAGTGGAGCAGGTGCCGCATGAGACACGTCCCAGTGAGATGGGTTCGCAGATGGAGAGGTCCACCAGCAGCGCCTAA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEITNSDMYSTHTSSSYSPSISDGTMTPNSHHLPGAPTSVAASGQEDHHHSTDGKLNGGTDGEELAKPKRLPHFHHHHHHHYHHQQALKIANKLRKINKEAKMGAGGGAGAGGAGSKFDKLTGEGIKARGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCSKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASASVSSNGSLQKRRYALALASDSSPSRLDFPKRSRSSHVAGNGGGGTTTTTATPTPLLRCSYCPKATEFSSLEQLNVHLQSVHEQQHQHAAKPPVAPESEGFQLSCEYCTMKFGNIAGLFQHMRNTHLDRLSSPNSYYEHFNRLATAGTFSPRLALELPKIKPDLGSPERESTRAAEEDLPTDLSSNKRRSQTPTNAQQVQSQQLAPPAAPPGVFFCNQCNAGLPDFESFRNHLKSHIAEGMQMVCPHCGLSLPEQSEFERHVVGHFLITGSEFNCSSSCGKSFAKSEDLQQHLLSEHVLTLLKCSLCSELCESRMAMQLHLACAHSQETKLLRCSACLELFRSDAEFHVHVKTRHQLGGGHPALGATPSAPANPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGGVKDKEQQRGSPNMGSLYVNALLPPLAAAAAAAAATNNNSSTIDYNVAFKGLFGGGAGGGSASGAGSGAGGGSGTAPPSGNKFYSPLQVDTNALKAQTSPHPALMYGLSQRYLMEMYAAKSTSPAGGNEGNPQPPQATAPPSAPPSAAPAAATFSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCAGNFKSRAELEQHMKSCHNSTGKHKCLICDEVFPSPAILAEHKLQHSKVGQSGKCSHCGQPLEDVAAFRAHLSEHGSDGATLPLACICCRQTLHSEFELSLHAKFHTKSASSGGSLQEPVCALCLEPLPDVPVEGPAKLCEKCCRKHNLNGKRGKPSDQPLQAPPSSAGAGSGAAFVENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPGGLLNHMAEHGAHSRPYDCSLCPEKFYFRAELEHHQRSHELRPQASRPPPMPKVEAPSIRNSSPICESPPSRSRSPTINVKQELYETDTVESGAGEDEPEENPQEDEEYIEVEQVPHETRPSEMGSQMERSTSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00548267;
90% Identity: iTF_00488807;
80% Identity: -