Basic Information

Insect: Drosophila lutescens
Gene Symbol: L_1
Assembly: GCA_037075285.1
Location: JBAMCF010000598.1:1069291-1075819[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 4.5e-05 0.0037 17.9 3.0 1 23 152 174 152 174 0.98

2 18 0.16 13 6.7 7.3 1 23 180 202 180 202 0.97

3 18 1.8e-07 1.4e-05 25.5 3.2 1 23 208 230 208 230 0.99

4 18 1.3e-05 0.0011 19.6 0.4 1 23 236 258 236 258 0.99

5 18 0.013 1 10.2 0.2 2 23 338 362 337 362 0.92

6 18 0.0016 0.13 13.1 0.4 2 23 383 405 382 405 0.96

7 18 0.065 5.3 8.0 0.7 1 23 489 511 489 511 0.97

8 18 0.0037 0.3 11.9 0.1 2 23 519 540 518 540 0.91

9 18 9.8e-05 0.0079 16.9 0.4 1 23 548 572 548 572 0.94

10 18 1.9 1.5e+02 3.4 0.2 2 20 578 596 577 597 0.93

11 18 5.3 4.2e+02 2.0 0.9 2 23 608 630 607 630 0.94

12 18 0.0027 0.22 12.4 1.1 1 23 675 698 675 698 0.97

13 18 0.0052 0.42 11.4 1.2 2 23 883 905 882 905 0.96

14 18 0.042 3.4 8.6 0.1 1 23 911 933 911 933 0.92

15 18 0.051 4.1 8.3 0.1 2 23 941 962 940 962 0.96

16 18 0.78 63 4.6 0.5 2 23 1060 1081 1060 1081 0.94

17 18 0.021 1.7 9.5 0.0 1 23 1091 1113 1091 1113 0.95

18 18 0.00036 0.029 15.1 1.2 1 23 1120 1142 1120 1142 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	4.5e-05	0.0037	17.9	3.0	1	23	152	174	152	174	0.98
2	18	0.16	13	6.7	7.3	1	23	180	202	180	202	0.97
3	18	1.8e-07	1.4e-05	25.5	3.2	1	23	208	230	208	230	0.99
4	18	1.3e-05	0.0011	19.6	0.4	1	23	236	258	236	258	0.99
5	18	0.013	1	10.2	0.2	2	23	338	362	337	362	0.92
6	18	0.0016	0.13	13.1	0.4	2	23	383	405	382	405	0.96
7	18	0.065	5.3	8.0	0.7	1	23	489	511	489	511	0.97
8	18	0.0037	0.3	11.9	0.1	2	23	519	540	518	540	0.91
9	18	9.8e-05	0.0079	16.9	0.4	1	23	548	572	548	572	0.94
10	18	1.9	1.5e+02	3.4	0.2	2	20	578	596	577	597	0.93
11	18	5.3	4.2e+02	2.0	0.9	2	23	608	630	607	630	0.94
12	18	0.0027	0.22	12.4	1.1	1	23	675	698	675	698	0.97
13	18	0.0052	0.42	11.4	1.2	2	23	883	905	882	905	0.96
14	18	0.042	3.4	8.6	0.1	1	23	911	933	911	933	0.92
15	18	0.051	4.1	8.3	0.1	2	23	941	962	940	962	0.96
16	18	0.78	63	4.6	0.5	2	23	1060	1081	1060	1081	0.94
17	18	0.021	1.7	9.5	0.0	1	23	1091	1113	1091	1113	0.95
18	18	0.00036	0.029	15.1	1.2	1	23	1120	1142	1120	1142	0.97

Sequence Information

Coding Sequence: ATGATGGCCCTAAAGATGTTATATCGCGGTCCCAGTTCGCGTTTGgagaatttaattgaaaagatCCAGGCCACCAAGGAGATAACTAATAACGATATGTACAGTACCCACACATCGTCCAGTTATTCGCCTAGTATTTCTGACGGCACCATGACTCCCAACTCCCACCACTTGCCTGGAGCTCTAGCAACCGCTGGTCAGGAGGATCATCCCACTGAGGGCAAGATCAACGGAGGAGCTGAAGGCGGGGAGTTGCCCAAGCCAAAGCGATTGCCCCACttccatcaccatcaccaatACCACCATCAACAGGCGCTGAAGATAGCCAACAAGCTGCGGAAAATCAATAAGGAAGCCAAAATGGGAGCTAGCGCCGGTGCAGGATCCACTGGAGCAGTCTCCAAGTTTGATAAGTTGACAGGAGAGGGGATTAAAAGTCGCGGCGACGGCTCCTATCAGTGCCAGTTCTGCGAGAAGACATTTCCACGACTCGGCTACTTGAAGCATCACGTACAGAGCCACGCTGAACACCTGCCTTTCAAGTGCGAATACTGCTCCAAGCTGTTCAAGCACAAGCGTTCCCGAGATCGCCATAAGAAGTTGCATACCAACGAGCGGAACTACAAGTGTCCGCATTGCGAGGCAGCTTTTTCCAGAAGTGACCACTTGAAGATTCACATGAAGACCCATGACATCCAGAAACCCTTCCAGTGCAGCATGTGCAACCGGGGCTACAATACAGCCGCTGCCCTAACCTCTCACATGCAAAAGCACAAGAAGAATGCTGCCATCCTGGCAGCTGGTGGCAATCCCAATGCCCTGAACTACAGTCCACGATCGACGGGATCGGCTTCGGCATCGGTTTCCAGTAATGGTAGTCTGCAGAAGAGACGCTATGCCTTGGCCCTGGCTTCGGATAGTAGTCCCAGTCGATTGGATTTCCCCAAGAGATCGAGAAGTAGTCATGTGGGTGGCACAAACATCACCACTGCTACGCCCACTCCTTTGCTAAGATGCAGTTACTGCCCCAAGGTCACCGAATTCAGTAGCCTGGAGCAACTGAATGCCCATCTCCAGAGTGTCCacgagcagcaacagcagccggtGAAGAACACTCCAGTTCAGGAGGCGGAGGGCTTCCAGCTGAGCTGCGAGTACTGCACCATGAAGTTTGGCAACATCGCCGGACTCTTCCAGCACATGCGAAGCACCCACATGGACCGATTGAGCAGCCCGAACTCCTATTACGAGCACTTCAATCGCCTGGCCACCGCTGGCACCTTCAGTCCACGACTGGCCATGGATTTGCCCAAAATTAAACCGGATTTGGGCAGCCCTGAGAGGGATTCACGACCCGCAGAGGACGATCTGCCCACGGATTTGAGCAGCAACAAGAGGCGACCACTGACACCGAATCCTCAGACCCAAACTCAACTACCACCACCCTCCGCTCCACCGGGGGTCTTCTTCTGCAACCAGTGCAACGCCGGTCTGCCCGATTTCGAGAGCTTCAGGAATCATCTGAAGAGTCACATTGCCGAGGGCATGCAACTGGTTTGTCCGCATTGCGGTTTGAGTTTGCCGGAGCAATCGGAGTTCGAACGTCATGTGGTGGGACACTTCCTAATCACCGGATCCGAGTTCAACTGTAGTTCGTCGTGCGGCAAGAGCTTTGCCAAGTCGGAGGATCTGCAGCAACATTTGCTTTCGGAGCACGTCCTCACCCTGCTGAAGTGCTCTTTGTGCTCGGAAGTCTGTGAGAGTCGCATGGCCATGCAGCTGCATTTGGCCTGCTCTCATAGTCAGGAAACGAAGCTGCTTCGCTGCAGCGCCTGTTTGGAACTCTTCCGATCCGATGCCGAGTTCCATGTGCATGTGAAGACGCGTCATCAGTTGGGCGGACatcccacgttgggcgccaattcaAATCCGCCCACCAATCCGCTGCAGTGCATGTTCTGTCGAGCCGTTTGTTCTTCTGAGCTGGAGATGCACTTCCATCTGGCGGCCCATGCGCGCCAGTTCAGATGTCCCTCCTGCCCGGAGACCTTCCATGTGGAGTTCCTGCTGGACCGTCATATGCAGAGCCAGCATGGCGGCGTCAAGGACAAGGAGGCCAACTCCCCCAACATGGGCAGCCTCTATGTGAATGCCTTGCTGCCTCCTttggcggcagcggcggcggcagcagcggccacCAATAACAACAGCAGTATCATCGACTACAATGTGGCATTCAAGGGTTTATTCGGAGGAGGTGCTGCAGGAGGTGCAGcatcaggaggaggaggagcaactGGAGGAGGACCTCCACCTTCGAGCAACAAATTCTACAGTCCCCTTCAAGTAGACACCAATGCACTGAAAGCCCAGACCTCCCCCCACCCGGCCTTGATGTATGGTCTCAGTCAACGGTATCTGATGGAGATGTATGCCGCCAAGTCCACATCGCCAGCCGGAAACGAGGGAGTTGGAAACCCACAGCCATCTCAGGCTTCCCAGGCAaccgcaccaccaccaccgccacccaaTCCAGCGACTGCCACTTTCAGTTGCGGAATGTGCGAGCGACAGGATTTGCGTAGCGAGGCGGAACTTCACTCCCATCGCAAATTGGCCCACAATCTAAAGACGGGTGTGAGTCTGCGATGTGCCTACTGTGCTGGAAACTTCAAATCTCGTGCGGAGTTGGAGCAACACATGAAGAGCTGTCACAATTCGACGGGCAAACACAAGTGCTTGATATGCGATGAGGTATTTCCCTCGCCAGCCATCCTGGCCGAACACAAGCTGCAGCACTCGAAGGTGGGGCAGTCGGGCAAGTGCTCCCATTGCGGACAGCCCCTCGAGGACGTGGCCGCCTTCAGGGCTCATCTCTCGGAGCATGGAAGCGATGGTGGCTCCTTACCACTGGCCTGCATCTGCTGTCGCCAGACCTTGCATTCGGAATTTGAGCTCAGTTTGCATGCCAAATTCCATACCAAGTCCTCCTCGAGCGGTGGCAGCCTGCAGGAACCAGTGTGTGCTTTGTGCCTGGAGCCTCTGCCCGATGCCACCGAAGGACCAGCGAAGCTCTGCGACAAGTGCTGTCGTAAGCACAATCTGAATGGCAAGCGGGGTAAGCACACGGAGCCACCGGCAGCCCTTCAACCTCCGAGTTCGTCCTTTGTGGAGAACCGCTGTAACCTTTGCAAGATGATCCTGCCACATGCCCAGAAGCTGCAGGAACACCTAGTGGAACACACCTTTGCGGGCACCGAACAGCGTGGTTTCAATTGCTACATTTGCTCCGCGGTTTTCACCGCACCCGGTGGACTGCTCAACCACATGGGCGAACATGGAGCTCATTCGCGACCCTACGATTGCAGTCTTTGCCCGGAAAAGTTCTACTTCCGCGCCGAGTTGGAACACCATCAAAGGGGTCATGAGCTGAGGCCACGTCCTCCGCAACCCAAAGTAGAGGTAACCTCCATCCAGAGGAACAGTTCACCCAGCCAGAGTCCCACGGTGCGGAGTCCCACGATTGTCAAGCAAGAACTATACGAAACGGATACGGTGGAGTCCACCGGAGCAGAGGATGAGCCGGAGAATCCTCCCGATGAGGAGGAGTACATCGAAGTGGAACAAATGCCGCACGAGACACGTCCAAGTGAGATTGGGTCGCAATTGGAAAGGTCCACCAGTAGCGCCTAA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEITNNDMYSTHTSSSYSPSISDGTMTPNSHHLPGALATAGQEDHPTEGKINGGAEGGELPKPKRLPHFHHHHQYHHQQALKIANKLRKINKEAKMGASAGAGSTGAVSKFDKLTGEGIKSRGDGSYQCQFCEKTFPRLGYLKHHVQSHAEHLPFKCEYCSKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASASVSSNGSLQKRRYALALASDSSPSRLDFPKRSRSSHVGGTNITTATPTPLLRCSYCPKVTEFSSLEQLNAHLQSVHEQQQQPVKNTPVQEAEGFQLSCEYCTMKFGNIAGLFQHMRSTHMDRLSSPNSYYEHFNRLATAGTFSPRLAMDLPKIKPDLGSPERDSRPAEDDLPTDLSSNKRRPLTPNPQTQTQLPPPSAPPGVFFCNQCNAGLPDFESFRNHLKSHIAEGMQLVCPHCGLSLPEQSEFERHVVGHFLITGSEFNCSSSCGKSFAKSEDLQQHLLSEHVLTLLKCSLCSEVCESRMAMQLHLACSHSQETKLLRCSACLELFRSDAEFHVHVKTRHQLGGHPTLGANSNPPTNPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGVKDKEANSPNMGSLYVNALLPPLAAAAAAAAATNNNSSIIDYNVAFKGLFGGGAAGGAASGGGGATGGGPPPSSNKFYSPLQVDTNALKAQTSPHPALMYGLSQRYLMEMYAAKSTSPAGNEGVGNPQPSQASQATAPPPPPPNPATATFSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCAGNFKSRAELEQHMKSCHNSTGKHKCLICDEVFPSPAILAEHKLQHSKVGQSGKCSHCGQPLEDVAAFRAHLSEHGSDGGSLPLACICCRQTLHSEFELSLHAKFHTKSSSSGGSLQEPVCALCLEPLPDATEGPAKLCDKCCRKHNLNGKRGKHTEPPAALQPPSSSFVENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPGGLLNHMGEHGAHSRPYDCSLCPEKFYFRAELEHHQRGHELRPRPPQPKVEVTSIQRNSSPSQSPTVRSPTIVKQELYETDTVESTGAEDEPENPPDEEEYIEVEQMPHETRPSEIGSQLERSTSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00548267;
90% Identity: iTF_00504840;
80% Identity: -