Basic Information

Insect: Drosophila tsacasi
Gene Symbol: L
Assembly: GCA_018904565.1
Location: JAEIHY010019593.1:1882-9092[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 9.1e-06 0.00091 19.8 2.9 1 23 160 182 160 182 0.98

2 17 0.14 14 6.7 7.3 1 23 188 210 188 210 0.97

3 17 1.5e-07 1.5e-05 25.5 3.2 1 23 216 238 216 238 0.99

4 17 1.1e-05 0.0011 19.6 0.4 1 23 244 266 244 266 0.99

5 17 0.011 1.1 10.2 0.2 2 23 351 375 350 375 0.92

6 17 0.0014 0.14 13.0 0.4 2 23 398 420 397 420 0.96

7 17 0.055 5.5 7.9 0.7 1 23 506 528 506 528 0.97

8 17 0.0038 0.38 11.6 0.1 2 23 536 557 535 557 0.92

9 17 8.4e-05 0.0084 16.8 0.4 1 23 565 589 565 589 0.94

10 17 4.5 4.5e+02 1.9 0.9 2 23 625 647 624 647 0.94

11 17 0.0023 0.23 12.3 1.1 1 23 693 716 693 716 0.97

12 17 0.0044 0.44 11.4 1.2 2 23 908 930 907 930 0.96

13 17 0.036 3.6 8.5 0.1 1 23 936 958 936 958 0.92

14 17 0.043 4.3 8.3 0.1 2 23 966 987 965 987 0.96

15 17 0.66 66 4.6 0.5 2 23 1094 1115 1094 1115 0.94

16 17 0.0086 0.86 10.5 0.0 1 23 1125 1147 1125 1147 0.96

17 17 0.00015 0.015 16.0 1.7 1 23 1154 1176 1154 1176 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	9.1e-06	0.00091	19.8	2.9	1	23	160	182	160	182	0.98
2	17	0.14	14	6.7	7.3	1	23	188	210	188	210	0.97
3	17	1.5e-07	1.5e-05	25.5	3.2	1	23	216	238	216	238	0.99
4	17	1.1e-05	0.0011	19.6	0.4	1	23	244	266	244	266	0.99
5	17	0.011	1.1	10.2	0.2	2	23	351	375	350	375	0.92
6	17	0.0014	0.14	13.0	0.4	2	23	398	420	397	420	0.96
7	17	0.055	5.5	7.9	0.7	1	23	506	528	506	528	0.97
8	17	0.0038	0.38	11.6	0.1	2	23	536	557	535	557	0.92
9	17	8.4e-05	0.0084	16.8	0.4	1	23	565	589	565	589	0.94
10	17	4.5	4.5e+02	1.9	0.9	2	23	625	647	624	647	0.94
11	17	0.0023	0.23	12.3	1.1	1	23	693	716	693	716	0.97
12	17	0.0044	0.44	11.4	1.2	2	23	908	930	907	930	0.96
13	17	0.036	3.6	8.5	0.1	1	23	936	958	936	958	0.92
14	17	0.043	4.3	8.3	0.1	2	23	966	987	965	987	0.96
15	17	0.66	66	4.6	0.5	2	23	1094	1115	1094	1115	0.94
16	17	0.0086	0.86	10.5	0.0	1	23	1125	1147	1125	1147	0.96
17	17	0.00015	0.015	16.0	1.7	1	23	1154	1176	1154	1176	0.98

Sequence Information

Coding Sequence: ATGATGGCCCTAAAGATGTTATATCGCGGTCCCAGCTCGCGTTTGGAGAATTTAATTGAAAAGATCCAGGCCACCAAGGAGATAACCAATAGCGACATGTACAGTACCCACACATCGTCCAGTTATTCGCCTAGCATTTCGGATGGCACCATGACGCCCAATTCCCACCATTTGCCCGGAGCTCCAATCTCTGTGGCCGCCTCTGGCCAGGAGGATCACCATCATCATTCCAGCGATGGCAAGCTCAACGGTGGCACCGATGGCGAGGAGCTGGCCAAACCGAAGCGCTTGCCACACTTCCATCAACATCACCATCATCACTACCACCATCAGCAGGCGCTGAAAATCGCCAACAAGCTGCGCAAAATCAATAAGGAAGCCAAAATGGGAGCTGGCGGCGGTGCTGGTGCCGGAGGAGCAGGCTCCAAGTTTGATAAGTTGACAGGCGAGGGGATTAAGGCCCGCGGCGACGGCTCCTATCAGTGTCAGTTCTGCGATAAGTCATTTCCGCGTCTCGGCTACTTGAAGCATCATGTGCAGAGCCACGCCGAACACCTGCCCTTCAAGTGCGAATACTGCTCGAAGCTGTTCAAGCACAAGCGATCCCGGGATCGCCACAAGAAGCTGCATACCAACGAGCGCAACTACAAGTGTCCCCATTGCGAGGCGGCCTTCTCCAGGAGTGACCACCTGAAGATCCACATGAAGACGCACGACATCCAGAAGCCGTTCCAGTGCAGCATGTGCAACCGGGGCTATAACACGGCGGCCGCCCTGACCTCGCACATGCAGAAGCACAAGAAGAATGCGGCCATCCTGGCCGCTGGCGGTAATCCCAATGCCCTGAACTACAGTCCCCGATCCACGGGATCGGCTTCGGCCTCGGTCTCCAGCAATGGCAGTCTGCAGAAGAGGCGCTATGCCCTGGCCCTGGCTTCAGATAGTAGTCCCAGCAGATTGGACTTCCCCAAGAGATCCAGGAGCAGTCATGTGGCTGGCAACGGAGGCGGCACCACCACCACGACGACGGCCACACCCACGCCCCTGCTCAGGTGCAGCTACTGTCCCAAGGTCACGGAGTTTAGCAGCTTGGAGCAGCTGAATGCCCACCTGCAGAGTGTCCACGAGCAGCAGCCCCAGCATGCGGCCAAGACGCCGGTGGCTCCGGCGGAGAGCGAAGGCTTCCAGCTGAGCTGCGAGTATTGCACCATGAAGTTCGGCAATATAGCAGGACTCTTCCAGCACATGAGGAGCACTCACCTGGACAGATTGAGCAGCCCGAACTCCTACTACGAGCACTTCAATCGCCTGGCCACCGCTGGCACCTTCAGTCCGCGTCTGGCCCTGGAGTTGCCCAAAATCAAGCCGGATTTGGGCAGCCCGGAGAGGGAGACCTCGCACCGAGGTGCAGAGGAGGATCTGCCCACCGATTTGAGCAGCAACAAACGGCGACCTCAGACACCTCAGCTGCAGTCCCAGCAGCAGCTGGCACCACCAGCCGCTCCTCCTGGGGTGTTCTTCTGCAATCAGTGCAACGCCGGGCTGCCGGATTTCGAGAGCTTTAGGAATCACCTGAAGAGCCACATCGCCGAGGGCATGCAGATGGTGTGTCCCCACTGCGGACTGAGCCTGCCGGAGCAGTCGGAGTTCGAGCGCCATGTGGTGGGCCACTTCCTCATCACCGGCTCCGAGTTCAACTGCAGCTCCAGCTGCGGCAAGAGCTTCGCCAAGTCGGAGGACCTGCAGCAGCACCTGCTGTCCGAGCACGTGCTCACTCTGCTGAAGTGCTCGCTGTGCTCGGAGCTCTGCGAGAGCCGGATGGCCATGCAGCTGCACCTGGCTTGTGCCCACAGCCAGGAGACGAAGCTGTTGCGCTGCAGCGCCTGCCTGGAGCTCTTCCGCTCCGATGCCGAGTTCCATGTGCATGTGAAGACGCGCCACCAGTTGGGGGGTGGTCATCCCGCGCTGGGCGCCACACCGAGTGCTCCTGCCAATCCCCTGCAGTGCATGTTCTGCCGGGCAGTCTGCTCCTCGGAGCTGGAGATGCATTTCCATCTGGCGGCGCACGCCAGGCAGTTCAGGTGCCCCTCCTGCCCGGAGACCTTCCACGTGGAGTTCCTGCTGGACAGGCACATGCAGAGCCAGCATGGCGGCGGCGGGGCCAAGGACAAGGAGCAGCAGCGGGGCTCGCCCAACATGGGCAGTCTCTATGTGAATGCCCTGCTGCCTCCTCTGGCGGCAGCGGCGGCGGCAGCAGCGGCCACCAACAACAACAGCAGCATCATCGACTACAATGTGGCATTCAAGGGCCTGTTTGGAGGCGGAGCAGGAGGAGGAGCAGCCTCTGGAGCAGGATCGGGCTCGGGAGGAGGCTCTGGAGCAGCCCCAGCCTCGAGCAACAAGTTCTACAGTCCCCTGCAGGTGGACACCAATGCCCTGAAGGCTCAGACCTCTCCGCATCCCGCCCTCATGTACGGCCTGAGTCAGCGCTATCTGATGGAGATGTACGCCGCCAAGTCCACCTCACCGGCAGGCGGCAACGAGGGCAATCCACAGCCACCACAGGCCACTGCTCCGCCGAGTGCCGCTCCACCGAGTGCTGCTCCAGCTCAGTCTGCAACCTTCAGTTGTGGCATGTGCGAGCGCCAGGATCTGCGCAGCGAGGCGGAGCTCCACTCGCACCGCAAGCTGGCCCACAACCTCAAGACGGGCGTGAGCCTAAGGTGTGCCTACTGCGCCGGGAACTTCAAGTCGCGGGCGGAGCTGGAGCAGCACATGAAGAGCTGCCACAACTCGACGGGCAAGCACAAGTGCCTGATCTGCGACGAGGTCTTCCCCTCCCCGGCCATCCTGGCCGAGCACAAGCTGCAGCACTCGAAGGTGGGCCAGTCGGGCAAGTGCTCCCACTGCGGCCAGCCGCTGGAGGATGTGGCCGCCTTCCGGGCTCACCTCTCGGAGCACGGCAGCGACGGGGCCACCCTGCCGCTGGCCTGCATCTGCTGTCGCCAGACCCTGCACTCGGAGTTCGAGCTGAGCCTGCATGCCAAGTTCCACACCAAGTCGGCCTCGAGCGGGGGCAGCCTCCAGGAGCCGGTGTGTGCTCTGTGCCTGGAACCGCTGCCGGATGGGCCAGTCGAGGGTCCGGCCAAGCTGTGCGAGAAGTGCTGTCGGAAGCACAACCTCAACGGAAAGCGGGGAAAGCCAAGTGACCAGCCGCTGCAGGCACCTCCATCATCGGGAGGAGCGGGATCGGGATCAGGAGCTGCCTTTGTGGAGAACCGCTGCAACCTGTGCAAGATGATCCTGCCGCATGCCCAGAAGCTCCAGGAACACCTGGTGGAGCACACCTTTGCGGGCACCGAGCAGCGCGGCTTCAACTGCTACATCTGCTCGGCGGTATTCACGGCCCCGGGAGGCTTGCTCAATCACATGGCCGAGCATGGAGCCCATTCGCGTCCCTACGACTGCAGCCTGTGTCCGGAGAAGTTCTACTTCCGGGCGGAGCTGGAGCACCATCAGCGGAGTCACGAGCTGAGGCCGCAGGCCACGAGGCCACCCATGCCCAAGGTGGAGGCACCCTCCATTAGGAATAGTTCACCCATATGCGAGAGTCCTCCTTCCAGGAGTCGCAGTCCCACGATCAAGCAGGAACTCTACGAAACGGACACTGTGGAGTCGGGAGCCGGAGAAGATGAGCCAGAGGAGAATCCCCAAGAAGATGAGGAGTACATTGAAGTGGAGCAGGTGCCGCATGAGACGCGTCCCAGTGAGATGGGTTCGCAAATGGAGAGGTCCACCAGTAGCGCCTAA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEITNSDMYSTHTSSSYSPSISDGTMTPNSHHLPGAPISVAASGQEDHHHHSSDGKLNGGTDGEELAKPKRLPHFHQHHHHHYHHQQALKIANKLRKINKEAKMGAGGGAGAGGAGSKFDKLTGEGIKARGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCSKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASASVSSNGSLQKRRYALALASDSSPSRLDFPKRSRSSHVAGNGGGTTTTTTATPTPLLRCSYCPKVTEFSSLEQLNAHLQSVHEQQPQHAAKTPVAPAESEGFQLSCEYCTMKFGNIAGLFQHMRSTHLDRLSSPNSYYEHFNRLATAGTFSPRLALELPKIKPDLGSPERETSHRGAEEDLPTDLSSNKRRPQTPQLQSQQQLAPPAAPPGVFFCNQCNAGLPDFESFRNHLKSHIAEGMQMVCPHCGLSLPEQSEFERHVVGHFLITGSEFNCSSSCGKSFAKSEDLQQHLLSEHVLTLLKCSLCSELCESRMAMQLHLACAHSQETKLLRCSACLELFRSDAEFHVHVKTRHQLGGGHPALGATPSAPANPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGGGAKDKEQQRGSPNMGSLYVNALLPPLAAAAAAAAATNNNSSIIDYNVAFKGLFGGGAGGGAASGAGSGSGGGSGAAPASSNKFYSPLQVDTNALKAQTSPHPALMYGLSQRYLMEMYAAKSTSPAGGNEGNPQPPQATAPPSAAPPSAAPAQSATFSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCAGNFKSRAELEQHMKSCHNSTGKHKCLICDEVFPSPAILAEHKLQHSKVGQSGKCSHCGQPLEDVAAFRAHLSEHGSDGATLPLACICCRQTLHSEFELSLHAKFHTKSASSGGSLQEPVCALCLEPLPDGPVEGPAKLCEKCCRKHNLNGKRGKPSDQPLQAPPSSGGAGSGSGAAFVENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPGGLLNHMAEHGAHSRPYDCSLCPEKFYFRAELEHHQRSHELRPQATRPPMPKVEAPSIRNSSPICESPPSRSRSPTIKQELYETDTVESGAGEDEPEENPQEDEEYIEVEQVPHETRPSEMGSQMERSTSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00548267;
90% Identity: iTF_00488807;
80% Identity: -