Dgua007306.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila guanche
Gene Symbol
L
Assembly
GCA_900245975.1
Location
NW:11253943-11280862[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 1.2e-05 0.00073 19.4 3.1 1 23 311 333 311 333 0.98
2 18 0.35 20 5.4 6.2 1 23 339 361 339 361 0.97
3 18 1.7e-07 9.8e-06 25.3 3.2 1 23 367 389 367 389 0.99
4 18 1.2e-05 0.00072 19.4 0.4 1 23 395 417 395 417 0.99
5 18 0.031 1.8 8.7 0.1 2 23 490 514 489 514 0.89
6 18 0.0038 0.22 11.6 0.2 2 23 546 568 545 568 0.95
7 18 0.061 3.6 7.8 0.7 1 23 651 673 651 673 0.97
8 18 0.003 0.18 11.9 0.1 2 23 681 702 680 702 0.91
9 18 0.0025 0.15 12.1 0.1 1 23 710 734 710 734 0.90
10 18 3.5 2.1e+02 2.3 0.1 2 20 740 758 739 759 0.92
11 18 1.3 76 3.6 0.9 2 23 770 792 769 792 0.95
12 18 0.0025 0.15 12.2 1.1 1 23 845 868 845 868 0.97
13 18 0.0049 0.29 11.2 1.2 2 23 1048 1070 1047 1070 0.96
14 18 0.11 6.7 7.0 0.1 1 23 1076 1098 1076 1098 0.92
15 18 2.5 1.5e+02 2.7 0.6 2 23 1106 1127 1106 1127 0.95
16 18 0.73 43 4.4 0.5 2 23 1229 1250 1229 1250 0.94
17 18 0.054 3.2 8.0 0.0 1 23 1260 1282 1260 1282 0.96
18 18 9.6e-05 0.0057 16.6 0.9 1 23 1289 1311 1289 1311 0.97

Sequence Information

Coding Sequence
ATGTCCCGACGCAAACAGGCCAAGCCGCGCGCCTGTCTCAAACTTGGcgaaaaggaggaggagcaggagcaaaagCCCAATGTGGATGACCTGCTGGAGCcgaaggaggagctgctcagTGCCGACgaggatggggatggggatggggatggggatgtggactccgatgaggaggaggatgctGAGGGAGAGCTGCTTACTGAGGAGAGGCCACTCAAGCCCAATGAATCACAGCCACAAAGCCACTGGACAACAGCTGATGAGGATCCAGGCAGGGCCTCGGCTGTGccaaaagaagaagcagaagaactACAACACCCACGGGATAAGGaaggtcctgctgctgtggctgctggtgcaTCCGGTGCAGCTGCCAATGCCAACGGGCACTGCAAGTCCTCTGGTAAcagTGAAAGCGCAGTGgaggaggaggagccagaAGACATGGACTTGGATGACGACCTGCTGAGTCTCAGCGGCGAAGAGGACTACGATGATGAAGAGCTGCAAAGTCTGGACAGCTTTTACTCAGACATGTACAGTACCCACACCTCGTCCAGCTACTCGCCGAGCATCTCCGATGGTACGATGACACCCAATGCCCATCATCTGGCGGCTGCCTCAGCGAATGCTTTACAGGAGGATCTCCACCTTCCGACTGATGGCAAGTCCAACGGCGTGCCCGGAGCGGAGGAGCCTGCCAAGCCTGCGAAGCGACAGCCGCACTtccatcatcaccatcatcactACCATCACCAGCAGGCCCTGAAGATTGCCAACAAGCTGCGCAAAATCAATAAGGAGGCCAAGCTGGCAGCCGCCGGAGGAGCAGGCGCTGGAGCCGGAGCAGGaactggcggtggcggtggtgcagCCGCAAAGTTTGATAAGTTGACAGGCGAAGGCATTAAGAGTCGCGGCGACGGCTCCTATCAGTGCCAGTTCTGTGATAAGACATTTCCCCGTCTCGGCTACCTGAAGCATCACGTGCAGAGCCATGCCGAGCACTTGCCCTTCAAGTGCGAGTACTGCGCCAAGCTGTTCAAGCACAAGCGATCCCGGGATCGCCACAAGAAGCTGCACACCAACGAGCGGAACTACAAGTGTCCACACTGCGAGGCAGCCTTCTCCAGGAGCGATCACCTGAAGATCCACATGAAGACGCACGACATACAGAAACCCTTCCAGTGCAGCATGTGCAACAGAGGCTACAACACGGCTGCGGCACTCACCTCGCACATGCAGAAGCACAAGAAGAATGCCGCCATACTGGCAGCCGGCGGCAATCCCAATGCCCTCAACTATAGTCCCAGGTCCACGGGCTCCGCCTCAGCGTCCGTGTCCAGCAACGGGAGCCTGCACAAGCGGCGCTACgcgctggctctggccacCGACAGCAGTCCCAGTCGGCTGGACTTTCCCAAGAGATCGCGCAGCAGCCATGTGCCCACACCCAcgccgctgctgcgctgcaGCTACTGCCCCAAGGTGACAGAGTTCAGCAGCCTCGAGCAGCTGAATGCACATCTCCAGGGTGtccacgagcagcagcagcagcagcagcagcagtcccagcagGAGCGACAGCCATCGGCAAAGGGCAATCCCGTGCAGGAGGCAGACACCTTCCAGCTGAGCTGCGAATATTGCACCATGAAGTTCGGCAACATTGCCGGCCTCTTCCAGCACATGCGCGCCACCCACTTGGATCGTCTGAGCAGCCCCAACTCCTACTACGAGCACTTCAATCGCCTGGCCACCGCGGGCACCTTCAGCCCGAGACTGGCGCTGGATTTGCCCAAGATCAAGCCGGATCTGGGCAGCCCGGAGCGAGAGAACCGAGCCTCGGAGGAGGACCTGCCCACGGATCTGAGCAGCAACAAGCGCAGACCGCAGACACCAGCCAACAATCCTGCGCCCCATCCTCCTCCGCAGGCACCTCCTGGCATCTTCTTCTGCAACCAGTGCAACGCGGGCCTGCCCGACTTTGAGAGTTTCCGCAATCATCTGAAGAGTCACATAGCCGAGGGCATGCAGCTGGTCTGTCCCCACTGCGGGCTGAGTCTGCCGGAGCAGTCGGACTTCGAGCGGCACGTCGTGGGGCACTTCCTCATCGCCAGCGCCGAGTTCAACTGCGGCTCCAGCTGTGGCAAGAGCTTCGGCAAggcggaggagctgcagcagcacctcaTCGCCGAGCATGTCCTCACGCTGCTGAAGTGCGCCCTCTGCTCGGAGGTGTGCGACACGCGCATGGCCATGCAGCTCCATCTGGCCTGTGCCCACAGCCAGGAAACGAAGCTGCTGCGCTGCAGCGCCTGCATGGAGGTCTTCCGCTCCGACGGGGACTTCCATGTGCATGTCAAGACGCGCCACCAGCTGGGCGGcggccatcatcatcaccagcagcagcagcagcagcacccacaccAGCATCATCCAGCATCCAATCCGTTGCAGTGCATGTTCTGCCGTGCCGTTTGCTCCTCCGAGCTGGAGATGCACTTCCATTTGGCGGCGCATGCGCGACAGTTCCGCTGCCCCTCCTGCCCGGAGACCTTCCACGTGGAGTTTCTGCTGGACAGGCACATGCAGAGCCAGCATGGGGGAGCCAAGGACAAGGAGCAGgcccagtcccaatcccagaGCTCACCGAACATGGGCAGCCTCTATGTGAAcgcgctgctgccaccgctcgcagcagctgccgcagccgcagctgccaccaacaacaacagcagcatcatcgaCTACAACGTGGCCTTCAAGGGATTGTTCGGGGGAGGATCGACAGCCGGAGGCAGTGCACCCACTGGGTCCAAGTTCTACAGCCCGCTGCAGGTGGACACGAAGGCACAAACCTCGCCACATCCCGCCCTGATGTACGGCCTCAGCCAGCGCTATCTGATGGAGATGTACGCCGCCAAGTCCACGTCGCCGGTGAACAGCAACGCCAACGaatcagcaggaggaggacctggagctgctgctcctccaccagCAACACAAGCGCCTGCGCCGCAAGCCACTCCAGCTGCCACCTTCAGCTGCGGCATGTGCGAGCGGCAGGATCTGCGCAGCGAGGCGGAACTCCACTCGCACCGGAAGCTGGCCCACAACCTCAAGACCGGCGTCAGTCTGCGCTGCGCCTACTGTGCGGGCAACTTCAAGTCGCGggccgagctggagcagcacatGAAGAGCTGCCACAACTCGACGGGCAAGCACAAGTGCCTCATCTGCGACGAGATCTTCCCCTCGCCGGCCATCCTCGCGGAGCACAAGCTGCAGCACTCGAAGGTGGGGCAGTCGGGCAAGTGCGCCCACTGCAGCCATCCGCTGGAGGATGTCGCCGCCTTCCGGGCCCACCTCAGCGAACATGGCAGCGACGGGGCCTCACTGCCGCTGGCCTGCATCTGCTGTCGCCAGACCCTGCACTCGGAGTTCGAGCTGAGTCTCCATGCCAAGTTCCACACAAAGTCCGCGtccagcggcggcagcctGCAGGAGCCAGTCTGCGCCCTCTGCCTGGAGCCCCTGCCTGGTGCAGTGGAGGGTCCCACCACTCCGGCGAAGCTCTGCGAGAAGTGCTGCCGCAAGCACAACCTCAACGGCAAGCGGAGCAAGGGCAGCGAGGCGCCCGTGCTTCAGGCTCCTCCACCGGCGGCGCCCTACCTGGAGAACCGCTGCAACCTGTGCAAGATGATCCTGCCACACGCCCAGAAGCTGCAGGAGCACCTCGTGGAGCACACCTTTGCGGGCACCGAGCAGCGCGGCTACAACTGCTACATCTGCTCGGCTGTGTTTACGGCACCCGGCGGCCTCCTCGGCCACATGGCGGAGCACGGCGCCCACTCGCGGCCCTACGACTGCAGCATTTGCCCCGAGAAGTTCTACTTCCGCGCCGAGCTGGAGCACCACCAGCGGGCACACGAGCTGCGTCCGGCGGTGCATCGTCCAGCGTTGGCCAAGCCAGAGCCTCCGCTGCGACGCAGCGCCTCGcccagtccgagtccgagtcccgTGCGAAGTCCCACGACCGTCAAGCAGGAGCTCTACGACTCGGATACGGCGCACTCGGCTGGCGATCAGCCAGAGCCCGctgcggaggaggaggagtacatAGAGGTGGAGCAGATGCCACACGAGACGCGGCCCAGGGATGTCATGTCACAGCTGGAGAGGGCCACAAACAGCGCCTGA
Protein Sequence
MSRRKQAKPRACLKLGEKEEEQEQKPNVDDLLEPKEELLSADEDGDGDGDGDVDSDEEEDAEGELLTEERPLKPNESQPQSHWTTADEDPGRASAVPKEEAEELQHPRDKEGPAAVAAGASGAAANANGHCKSSGNSESAVEEEEPEDMDLDDDLLSLSGEEDYDDEELQSLDSFYSDMYSTHTSSSYSPSISDGTMTPNAHHLAAASANALQEDLHLPTDGKSNGVPGAEEPAKPAKRQPHFHHHHHHYHHQQALKIANKLRKINKEAKLAAAGGAGAGAGAGTGGGGGAAAKFDKLTGEGIKSRGDGSYQCQFCDKTFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASASVSSNGSLHKRRYALALATDSSPSRLDFPKRSRSSHVPTPTPLLRCSYCPKVTEFSSLEQLNAHLQGVHEQQQQQQQQSQQERQPSAKGNPVQEADTFQLSCEYCTMKFGNIAGLFQHMRATHLDRLSSPNSYYEHFNRLATAGTFSPRLALDLPKIKPDLGSPERENRASEEDLPTDLSSNKRRPQTPANNPAPHPPPQAPPGIFFCNQCNAGLPDFESFRNHLKSHIAEGMQLVCPHCGLSLPEQSDFERHVVGHFLIASAEFNCGSSCGKSFGKAEELQQHLIAEHVLTLLKCALCSEVCDTRMAMQLHLACAHSQETKLLRCSACMEVFRSDGDFHVHVKTRHQLGGGHHHHQQQQQQHPHQHHPASNPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGAKDKEQAQSQSQSSPNMGSLYVNALLPPLAAAAAAAAATNNNSSIIDYNVAFKGLFGGGSTAGGSAPTGSKFYSPLQVDTKAQTSPHPALMYGLSQRYLMEMYAAKSTSPVNSNANESAGGGPGAAAPPPATQAPAPQATPAATFSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCAGNFKSRAELEQHMKSCHNSTGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCSHPLEDVAAFRAHLSEHGSDGASLPLACICCRQTLHSEFELSLHAKFHTKSASSGGSLQEPVCALCLEPLPGAVEGPTTPAKLCEKCCRKHNLNGKRSKGSEAPVLQAPPPAAPYLENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGYNCYICSAVFTAPGGLLGHMAEHGAHSRPYDCSICPEKFYFRAELEHHQRAHELRPAVHRPALAKPEPPLRRSASPSPSPSPVRSPTTVKQELYDSDTAHSAGDQPEPAAEEEEYIEVEQMPHETRPRDVMSQLERATNSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00548267;
90% Identity
-
80% Identity
-