Basic Information

Insect: Drosophila kanapiae
Gene Symbol: L
Assembly: GCA_008042475.1
Location: VNJM01002694.1:299322-306684[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 9.5e-06 0.00076 19.9 2.9 1 23 161 183 161 183 0.98

2 17 0.14 11 6.7 7.3 1 23 189 211 189 211 0.97

3 17 1.6e-07 1.3e-05 25.5 3.2 1 23 217 239 217 239 0.99

4 17 1.2e-05 0.00092 19.6 0.4 1 23 245 267 245 267 0.99

5 17 0.017 1.4 9.6 0.2 2 23 351 375 350 375 0.92

6 17 0.0014 0.11 13.0 0.4 2 23 401 423 400 423 0.96

7 17 0.057 4.6 8.0 0.7 1 23 507 529 507 529 0.97

8 17 0.0039 0.31 11.6 0.1 2 23 537 558 536 558 0.92

9 17 8.7e-05 0.0069 16.8 0.4 1 23 566 590 566 590 0.94

10 17 4.6 3.7e+02 1.9 0.9 2 23 626 648 625 648 0.94

11 17 0.0024 0.19 12.3 1.1 1 23 693 716 693 716 0.97

12 17 0.0046 0.37 11.4 1.2 2 23 907 929 906 929 0.96

13 17 0.037 3 8.5 0.1 1 23 935 957 935 957 0.92

14 17 0.045 3.6 8.3 0.1 2 23 965 986 964 986 0.96

15 17 0.69 55 4.6 0.5 2 23 1087 1108 1087 1108 0.94

16 17 0.009 0.72 10.5 0.0 1 23 1118 1140 1118 1140 0.96

17 17 0.00032 0.025 15.1 1.2 1 23 1147 1169 1147 1169 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	9.5e-06	0.00076	19.9	2.9	1	23	161	183	161	183	0.98
2	17	0.14	11	6.7	7.3	1	23	189	211	189	211	0.97
3	17	1.6e-07	1.3e-05	25.5	3.2	1	23	217	239	217	239	0.99
4	17	1.2e-05	0.00092	19.6	0.4	1	23	245	267	245	267	0.99
5	17	0.017	1.4	9.6	0.2	2	23	351	375	350	375	0.92
6	17	0.0014	0.11	13.0	0.4	2	23	401	423	400	423	0.96
7	17	0.057	4.6	8.0	0.7	1	23	507	529	507	529	0.97
8	17	0.0039	0.31	11.6	0.1	2	23	537	558	536	558	0.92
9	17	8.7e-05	0.0069	16.8	0.4	1	23	566	590	566	590	0.94
10	17	4.6	3.7e+02	1.9	0.9	2	23	626	648	625	648	0.94
11	17	0.0024	0.19	12.3	1.1	1	23	693	716	693	716	0.97
12	17	0.0046	0.37	11.4	1.2	2	23	907	929	906	929	0.96
13	17	0.037	3	8.5	0.1	1	23	935	957	935	957	0.92
14	17	0.045	3.6	8.3	0.1	2	23	965	986	964	986	0.96
15	17	0.69	55	4.6	0.5	2	23	1087	1108	1087	1108	0.94
16	17	0.009	0.72	10.5	0.0	1	23	1118	1140	1118	1140	0.96
17	17	0.00032	0.025	15.1	1.2	1	23	1147	1169	1147	1169	0.97

Sequence Information

Coding Sequence: ATGATGGCCCTAAAGATGTTATATCGCGGTCCCAGTTCGCGTTTggagaatttaattgaaaagatCCAGGCCACCAAGGAGATAACCAATAACGACATGTACAGTACCCACACATCGTCCAGTTACTCGCCTAGCATTTCGGATGGCACCATGACGCCCAATTCCCACCATTTGCCCGGTGCTCCAacctctgccgccgccaccgcctctgGCCAAGAGGATCATCATCATGCCGCTGATGGCAAGCTCAATGGTGGCACCGATGGCGAGGAGCTGACCAAACCGAAGCGATTGCCACACtttcatcaccatcatcaccatcattatcatcatcagcaggcgCTGAAAATAGCCAACAAGCTGCGCAAAATCAATAAGGAAGCCAAAATGGGAGCTGGCGGCGTGGCTGGTGCCGGAGGAGCCGCCTCCAAGTTTGATAAGTTGACAGGCGAGGGGATTAAGGCGCGCGGCGACGGCTCCTATCAGTGTCAGTTCTGCGATAAGTCATTTCCGCGTCTCGGCTACTTGAAGCATCACGTACAGAGCCACGCCGAACACCTGCCCTTCAAGTGCGAATACTGCTCGAAGCTGTTCAAGCACAAGCGATCCCGCGATCGCCATAAGAAGTTGCATACCAACGAGCGCAACTACAAGTGTCCCCATTGCGAGGCGGCCTTCTCCAGGAGTGACCACCTGAAGATCCACATGAAGACGCACGACATCCAGAAGCCGTTCCAGTGCAGCATGTGCAATCGTGGCTATAATACGGCGGCCGCCCTGACCTCGCACATGCAGAAGCACAAGAAGAATGCGGCCATCCTGGCAGCCGGCGGTAATCCCAATGCCCTCAACTATAGTCCAAGATCCACGGGTTCGGCCTCGGCATCGGTCTCCAGCAATGGCAGTCTCCAAAAAAGACGAtatgctttggctttggcctcGGATAGTAGTCCCAGTCGCCTGGACTTCCCCAAGCGATCAAGGAGCAGTCATGTGGGTGGTAATGGTGGGGGTGGCACAACTACGACAGCCACACCCACTCCCCTGCTGAGGTGCAGCTACTGTCCCAAGGTCACGGAGTTTAGCAGCCTGGAGCAGCTCAATGTCCACCTGCAGAGTGtccacgagcagcagcagcagcagcagcatcagcatgcGGCCAAGACAGCGGTGGCCCAGGAGGGCGAGGGCTTCCAGCTGAGCTGCGAATATTGCACCATGAAATTTGGCAACATAGCCGGTCTCTTCCAGCACATGCGGAGCACTCACCTGGACAGGTTGAGCAGCCCGAACTCCTACTACGAGCACTTCAATCGCCTGGCCACGGCGGGCACTTTCAGTCCCCGTCTGGCCTTGGATTTGCCCAAAATCAAGCCGGATTTGGGGAGTCCAGAGAGGGAGTCAGGACGGGCTGCCGAGGAGGATTTGCCCACCGATTTGAGCAGCAACAAGAGGCGACCCCAGACACCGAatccgcagcaacaacagctggcACCGCCGGCTGCTCCGCCTGGAGTCTTCTTCTGCAATCAGTGCAACGCCGGTCTGCCGGATTTCGAGAGCTTCAGAAACCACCTGAAGAGTCACATCGCCGAGGGCATGCAGATGGTGTGTCCGCATTGCGGCCTGAGCCTGCCGGAGCAGTCGGAGTTCGAGCGCCATGTCGTGGGTCACTTTCTCATCACCGGCTCCGAATTCAACTGCAGCTCAAGCTGCGGCAAGAGCTTCGCCAAGTCGGAGGacctgcagcagcatctcctATCTGAGCATGTCCTCACCCTGCTGAAGTGCTCGCTGTGCTCGGAGCTCTGCGAGAGTCGGATGGCCATGCAGCTGCATCTGGCCTGTGCCCACAGCCAGGAGACGAAGCTGCTGCGCTGCAGCGCCTGCCTGGAGCTCTTCCGCTCCGATGCCGAGTTCCATGTGCATGTGAAGACGCGTCACCAGCTCGGGGGACATCCCTCGCTGGGTGCCACACCCAGTGCTCCGGCGAATCCGCTGCAGTGCATGTTCTGCCGGGCTGTCTGCTCCTCGGAACTGGAGATGCACTTCCACTTGGCGGCGCATGCGAGGCAGTTTAGGTGCCCCTCCTGCCCGGAGACCTTCCATGTGGAGTTCCTGCTGGATCGGCACATGCAGAGCCAGCATGGTGGCGGGGCCAAggacaaggagcagcagcaacggggCTCACCCAACATGGGCAGTCTCTATGTGAATGCATTGCTGCCTCCtctggcggcagcggcagcggcagcagcggccaccaacaacaacagcagcatcatcgaTTACAATGTGGCTTTCAAGGGATTGtttggaggaggcggaggaggaggagcagccgcgggagcaggagctgcctCAGGAGGAGGCTCTGGCGGAGCACCCCCTTCGGGCAACAAGTTCTACAGTCCCCTGCAGGTGGACACCAATGCCCTGAAAGCGCAGACTTCGCCGCATCCCGCCCTCATGTACGGCCTGAGTCAGCGCTATCTGATGGAGATGTACGCCGCCAAGTCCACATCGCCGGCGGGGGGCAATGAAAACAACCCTCAGCCACCACAGCCGCCTCACGCCAACGTTCCACCGCCACCGAGTGCCGCCCCAAGCGCTCCAACCTTCAGTTGCGGAATGTGCGAGCGCCAGGATCTGCGCAGCGAGGCGGAGCTCCACTCGCACCGGAAACTGGCCCACAACCTCAAGACCGGGGTGAGTCTGCGGTGTGCCTACTGCGCCGGGAACTTTAAGTCCCGGGccgagctggagcagcacaTGAAGAGCTGCCACAATTCGACGGGCAAGCACAAGTGCCTGATCTGCGACGAGGTCTTCCCCTCGCCGGCCATCCTGGCCGAGCACAAGCTGCAGCACTCGAAGGTGGGACAGTCCGGCAAGTGCTCCCACTGCGGCCAGCCGCTGGAGGATGTGGCCGCCTTCAGGGCTCATCTGTCGGAGCATGGCAGCGATGGAGCCACTCTGCCACTGGCCTGCATCTGCTGCCGCCAGACCCTGCACTCGGAGTTCGAACTCAGCCTCCATGCCAAGTTCCACACCAAGTCGGCGTCGAGTGGTGGTAGCCTCCAGGAGCCGGTGTGTGCTCTGTGCTTGGAGCCACTACCAGATGTTCCCGTCGAGGGTCCAGCCAAGCTGTGCGAGAAGTGCTGTCGGAAGCACAACCTGAATGGTAAGCGGGGCAAGCCCAGTGATCCTCCACTGCAGGCACCtccatcagcaggagcagttgCCTTTGTGGAAAACCGCTGCAACCTGTGCAAGATGATCCTGCCGCATGCCCAGAAGCTCCAGGAACACCTGGTGGAGCACACCTTTGCTGGCACCGAGCAGCGCGGCTTTAACTGTTACATCTGCTCGGCGGTGTTCACGGCCCCGGGTGGCCTTCTCAACCACATGGCAGAGCATGGAGCACACTCGCGGCCCTACGACTGCAGCCTGTGTCCGGAGAAGTTCTACTTCCGGGCGGAGTTGGAGCACCATCAGAGGGGTCACGAGCTGAGGCCAAAGCCCACAAGGCAGCCTATGCCCAAGGCGGAGGCGGCATCGTCCATTAGGAACAGTTCGCCTCTTTGCGAGAGTCCGCCTTCCAGAAGTCGCAGTCCCCCCATCAATGTCAAGCAGGAACTCTACGAAACAGACACACTGGAGTCGGGGGCAGGAGAGGATGAGCCAGAGAATCCCCCGGAAGATGAGGAGTACATTGAAGTGGAGCAGGTGCCGCATGAGACACGTCCCAGTGAGATAGGTTCGCACATGGAAAGGTCCACCAGTAGCGCCTAA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEITNNDMYSTHTSSSYSPSISDGTMTPNSHHLPGAPTSAAATASGQEDHHHAADGKLNGGTDGEELTKPKRLPHFHHHHHHHYHHQQALKIANKLRKINKEAKMGAGGVAGAGGAASKFDKLTGEGIKARGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCSKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASASVSSNGSLQKRRYALALASDSSPSRLDFPKRSRSSHVGGNGGGGTTTTATPTPLLRCSYCPKVTEFSSLEQLNVHLQSVHEQQQQQQHQHAAKTAVAQEGEGFQLSCEYCTMKFGNIAGLFQHMRSTHLDRLSSPNSYYEHFNRLATAGTFSPRLALDLPKIKPDLGSPERESGRAAEEDLPTDLSSNKRRPQTPNPQQQQLAPPAAPPGVFFCNQCNAGLPDFESFRNHLKSHIAEGMQMVCPHCGLSLPEQSEFERHVVGHFLITGSEFNCSSSCGKSFAKSEDLQQHLLSEHVLTLLKCSLCSELCESRMAMQLHLACAHSQETKLLRCSACLELFRSDAEFHVHVKTRHQLGGHPSLGATPSAPANPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGGAKDKEQQQRGSPNMGSLYVNALLPPLAAAAAAAAATNNNSSIIDYNVAFKGLFGGGGGGGAAAGAGAASGGGSGGAPPSGNKFYSPLQVDTNALKAQTSPHPALMYGLSQRYLMEMYAAKSTSPAGGNENNPQPPQPPHANVPPPPSAAPSAPTFSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCAGNFKSRAELEQHMKSCHNSTGKHKCLICDEVFPSPAILAEHKLQHSKVGQSGKCSHCGQPLEDVAAFRAHLSEHGSDGATLPLACICCRQTLHSEFELSLHAKFHTKSASSGGSLQEPVCALCLEPLPDVPVEGPAKLCEKCCRKHNLNGKRGKPSDPPLQAPPSAGAVAFVENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPGGLLNHMAEHGAHSRPYDCSLCPEKFYFRAELEHHQRGHELRPKPTRQPMPKAEAASSIRNSSPLCESPPSRSRSPPINVKQELYETDTLESGAGEDEPENPPEDEEYIEVEQVPHETRPSEIGSHMERSTSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00548267;
90% Identity: iTF_00488807;
80% Identity: -