Basic Information

Insect: Drosophila nikananu
Gene Symbol: L
Assembly: GCA_008042635.1
Location: VNJV01020854.1:5053-10408[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 8.5e-06 0.00096 19.9 2.9 1 23 121 143 121 143 0.98

2 17 0.13 14 6.7 7.3 1 23 149 171 149 171 0.97

3 17 1.4e-07 1.6e-05 25.5 3.2 1 23 177 199 177 199 0.99

4 17 1e-05 0.0012 19.6 0.4 1 23 205 227 205 227 0.99

5 17 0.01 1.1 10.2 0.2 2 23 312 336 311 336 0.92

6 17 0.0013 0.14 13.1 0.4 2 23 358 380 357 380 0.96

7 17 0.051 5.8 8.0 0.7 1 23 468 490 468 490 0.97

8 17 0.0035 0.39 11.7 0.1 2 23 498 519 497 519 0.92

9 17 7.8e-05 0.0088 16.9 0.4 1 23 527 551 527 551 0.94

10 17 4.2 4.7e+02 2.0 0.9 2 23 587 609 586 609 0.94

11 17 0.0021 0.24 12.4 1.1 1 23 655 678 655 678 0.97

12 17 0.0041 0.47 11.4 1.2 2 23 867 889 866 889 0.96

13 17 0.034 3.8 8.6 0.1 1 23 895 917 895 917 0.92

14 17 0.04 4.5 8.3 0.1 2 23 925 946 924 946 0.96

15 17 0.62 70 4.6 0.5 2 23 1054 1075 1054 1075 0.94

16 17 0.008 0.91 10.5 0.0 1 23 1085 1107 1085 1107 0.96

17 17 0.00014 0.016 16.0 1.7 1 23 1114 1136 1114 1136 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	8.5e-06	0.00096	19.9	2.9	1	23	121	143	121	143	0.98
2	17	0.13	14	6.7	7.3	1	23	149	171	149	171	0.97
3	17	1.4e-07	1.6e-05	25.5	3.2	1	23	177	199	177	199	0.99
4	17	1e-05	0.0012	19.6	0.4	1	23	205	227	205	227	0.99
5	17	0.01	1.1	10.2	0.2	2	23	312	336	311	336	0.92
6	17	0.0013	0.14	13.1	0.4	2	23	358	380	357	380	0.96
7	17	0.051	5.8	8.0	0.7	1	23	468	490	468	490	0.97
8	17	0.0035	0.39	11.7	0.1	2	23	498	519	497	519	0.92
9	17	7.8e-05	0.0088	16.9	0.4	1	23	527	551	527	551	0.94
10	17	4.2	4.7e+02	2.0	0.9	2	23	587	609	586	609	0.94
11	17	0.0021	0.24	12.4	1.1	1	23	655	678	655	678	0.97
12	17	0.0041	0.47	11.4	1.2	2	23	867	889	866	889	0.96
13	17	0.034	3.8	8.6	0.1	1	23	895	917	895	917	0.92
14	17	0.04	4.5	8.3	0.1	2	23	925	946	924	946	0.96
15	17	0.62	70	4.6	0.5	2	23	1054	1075	1054	1075	0.94
16	17	0.008	0.91	10.5	0.0	1	23	1085	1107	1085	1107	0.96
17	17	0.00014	0.016	16.0	1.7	1	23	1114	1136	1114	1136	0.98

Sequence Information

Coding Sequence: ATGTACAGTACCCACACTTCGTCCAGCTACTCGCCTAGCATTTCGGATGGCACCATGACGCCCAACTCCCACCATTTGCCCACCTCTGTGGCCGCCTCTGGCCAGGAGGATCATCATGATGGCAAGCTCAATGGTGGCACCGATGGCGAGGAGCTGGCCAAACCGAAACGCTTGCCACACttccatcaccatcaccatcatcactACCACCATCAGCAGGCGCTGAAAATCGCCAACAAGCTGCGCAAAATCAATAAGGAAGCCAAAATGGGAGCTGGCGGCGGTGCTGGTGCCGGAGGAGCAGGCTCCAAGTTTGATAAGTTGACGGGCGAGGGGATTAAGGCCCGCGGCGACGGCTCCTATCAGTGTCAGTTCTGCGATAAGTCATTTCCGCGTCTCGGCTACTTGAAGCATCACGTACAGAGCCACGCCGAACACCTGCCCTTCAAGTGCGAATACTGCTCGAAGCTGTTCAAGCACAAGCGATCCCGGGATCGCCACAAGAAGCTGCATACCAACGAGCGCAACTACAAGTGTCCCCATTGCGAGGCGGCCTTCTCCAGGAGTGACCACCTGAAGATCCACATGAAGACGCACGACATCCAGAAGCCGTTCCAGTGCAGCATGTGCAACCGGGGCTACAATACGGCGGCCGCCCTGACCTCGCACATGCAGAAGCACAAGAAGAATGCGGCCATCCTGGCCGCTGGGGGTAATCCCAATGCCCTGAACTACAGTCCCCGATCCACGGGCTCGGCCTCGGCCTCGGTCTCCAGCAATGGCAGTCTGCAGAAGAGGCGGTATGCCCTGGCTCTAGCCTCCGATAGTAGTCCCAGCCGGTTGGACTTCCCCAAGAGATCCAGGGGCAGTCATGTGGCTGGCAATGGGggcggcaccaccaccaccaccgcggCCACACCCACGCCCCTGCTCAGGTGCAGCTACTGCCCCAAGGTCACGGAGTTTAGCAGCTTGGAGCAGCTGAATGCCCACCTGCAGAGTGTCCACgagcagcagcctcagcatGCGGCCAAGACGCCTGTGGCTCCGGAGAGCGAGGGCTTCCAGCTGAGCTGCGAGTACTGCACCATGAAGTTCGGCAATATAGCAGGACTCTTCCAGCACATGCGGAGCACTCACCTGGACAGATTGAGCAGCCCGAACTCCTACTACGAGCACTTCAATCGCCTGGCCACCGCTGGCACCTTCAGTCCGCGGCTGGCCCTGGAGCTGCCTAAAATAAAGACGGATTTAGGCAGCCCGGAGAGGGAGACGCAGCGGGCTGCCGAGGATGATCTGCCCACCGATTTGAGCAGCAACAAGCGGCGACCCCAGACCCCCACGAATGCCCAGCAGTTGCAGTCCCAGCAGCTGGCACCCCCAGCCGCTCCTCCTGGGGTGTTCTTCTGCAATCAGTGCAACGCCGGGCTGCCGGACTTCGAGAGCTTTAGGAATCACCTGAAGAGCCACATCGCCGAGGGCATGCAGATGGTGTGTCCCCACTGCGGACTGAGCCTGCCGGAGCAGTCGGAGTTCGAGCGCCATGTGGTGGGCCACTTCCTCATCACCGGCTCCGAGTTCAactgcagctccagctgcgGCAAGAGCTTCGCCAAGTCGGAGGacctgcagcagcacctgCTGTCAGAGCACGTGCTCACCCTGCTGAAGTGCTCGCTGTGCTCGGAGCTCTGCGAGAGCCGGATGGCCATGCAGCTGCACCTGGCCTGTGCCCACAGCCAGGAGACGAAGCTGCTGCGCTGCAGCGCCTGCCTGGAGCTCTTCCGCTCCGATGCCGAGTTCCATGTGCATGTGAAGACGCGCCACCAGCTGGGCGGCGGTCATCCCGCGCTGGGCGCCGCCCCGAGTGCACCCGCCAATCCCCTGCAGTGCATGTTCTGCCGCGCTGTCTGCTCCTCGGAGCTGGAGATGCACTTCCATCTGGCGGCGCACGCCAGGCAGTTCAGGTGCCCCTCCTGCCCGGAGACCTTCCACGTGGAGTTCCTGCTGGACAGGCACATGCAGAGCCAGCACGGCGGCGGGGCCAAggacaaggagcagcagcggggcTCGCCCAACATTGGCAGTCTCTATGTGAATGCCCTGCTGCCTCCCctggcggcagcggcggcggcggcagcggccaccaacaacaacagcagcatcatcgACTACAATGTGGCATTCAAGGGTCTGTTTGGAGGCGGAGCAGGAGGGGGCGCAGCCTCTGGAGCGGTATCCGGGTCGGGAGGAGGATCCGGAGCAGCCCCGCCCGCGGGCAACAAGTTCTACAGTCCCCTGCAGGTGGACACCAATGCCTTGAAGGCACAGACCTCACCGCATCCCGCCCTCATGTACGGCCTGAGTCAGCGCTATCTGATGGAGATGTACGCCGCCAAGTCCACCTCGCCGGCGGGCGGCAACGAGGGCAATCCACAGCCACCACAGGCCACGGCTCCGCCGAGTGCGCCACCGAGTTCGGCTCCAGCCGCTGCCACCTTCAGCTGTGGCATGTGTGAGCGCCAGGATCTGCGCAGCGAGGCGGAGCTCCACTCGCACCGCAAGCTGGCCCACAACCTCAAGACGGGCGTGAGCCTCAGGTGCGCCTACTGTGCCGGGAACTTCAAGTCGCGGgcggagctggagcagcacaTGAAGAGCTGCCACAATTCGACGGGCAAGCACAAGTGCCTGATCTGCGACGAGGTCTTCCCCTCGCCGGCCATCCTGGCCGAGCACAAGCTGCAGCACTCGAAGGTGGGCCAGTCGGGCAAGTGCTCCCACTGCGGCCAGCCGCTGGAGGATGTGGCCGCCTTCAGGGCCCACCTCTCGGAGCACGGCAGCGACGGGGCCACCCTGCCGCTGGCCTGCATCTGCTGTCGCCAGACCCTGCACTCGGAGTTCGAGCTGAGCCTGCACGCGAAGTTCCACACCAAGTCGGCCTCCAGTGGGGGCAGCCTCCAGGAGCCGGTGTGTGCTCTGTGCCTGGAGCCACTGCCCGATGTGCCGCTCGAGGGTCCGGCCAAGCTGTGCGAGAAGTGCTGTCGCAAGCACAACCTCAATGGAAAGCGGGGAAAGCCAAGTGAGCAGCCGCTGCAGGCTCCtccatcatcagcagcaggaggaggtggaggatcAGGAGCTGCCTTTGTGGAGAACCGCTGCAATTTGTGCAAGATGATCCTGCCGCATGCCCAGAAGCTCCAGGAACACCTGGTGGAGCACACCTTTGCGGGCACCGAGCAGCGCGGCTTCAACTGCTACATCTGCTCGGCGGTATTCACGGCCCCGGGAGGCCTGCTCAATCACATGGCCGAGCATGGAGCGCATTCGCGTCCCTACGACTGCAGCCTGTGTCCGGAGAAGTTCTACTTCCGGGCGGAGCTGGAGCACCATCAGAGGAGCCACGAGCTGAGGCCACAGGCCACGAGGCCACCTATGCCGAAGGTGGAGGCTCCCTCCATCAGGAATAGTTCACCCATTTGCGAGAGTCCTCCCTCCCGGAGTCGCAGTCCCACGGTCAATGTCAAGCAGGAACTCTACGAAACGGACACCGTGGAGTCGGGAGCAGGAGAAGATGAGCCCGAGGAGAATGCCCAAGAAGATGAGGAGTACATTGAAGTGGAGCAGGTGCCGCATGAGACGCGTCCCAGTGAGCTGAGTTCGCAGCTGGAAAGGTCCACCAGTAGCGCCTGA
Protein Sequence: MYSTHTSSSYSPSISDGTMTPNSHHLPTSVAASGQEDHHDGKLNGGTDGEELAKPKRLPHFHHHHHHHYHHQQALKIANKLRKINKEAKMGAGGGAGAGGAGSKFDKLTGEGIKARGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCSKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASASVSSNGSLQKRRYALALASDSSPSRLDFPKRSRGSHVAGNGGGTTTTTAATPTPLLRCSYCPKVTEFSSLEQLNAHLQSVHEQQPQHAAKTPVAPESEGFQLSCEYCTMKFGNIAGLFQHMRSTHLDRLSSPNSYYEHFNRLATAGTFSPRLALELPKIKTDLGSPERETQRAAEDDLPTDLSSNKRRPQTPTNAQQLQSQQLAPPAAPPGVFFCNQCNAGLPDFESFRNHLKSHIAEGMQMVCPHCGLSLPEQSEFERHVVGHFLITGSEFNCSSSCGKSFAKSEDLQQHLLSEHVLTLLKCSLCSELCESRMAMQLHLACAHSQETKLLRCSACLELFRSDAEFHVHVKTRHQLGGGHPALGAAPSAPANPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGGAKDKEQQRGSPNIGSLYVNALLPPLAAAAAAAAATNNNSSIIDYNVAFKGLFGGGAGGGAASGAVSGSGGGSGAAPPAGNKFYSPLQVDTNALKAQTSPHPALMYGLSQRYLMEMYAAKSTSPAGGNEGNPQPPQATAPPSAPPSSAPAAATFSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCAGNFKSRAELEQHMKSCHNSTGKHKCLICDEVFPSPAILAEHKLQHSKVGQSGKCSHCGQPLEDVAAFRAHLSEHGSDGATLPLACICCRQTLHSEFELSLHAKFHTKSASSGGSLQEPVCALCLEPLPDVPLEGPAKLCEKCCRKHNLNGKRGKPSEQPLQAPPSSAAGGGGGSGAAFVENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPGGLLNHMAEHGAHSRPYDCSLCPEKFYFRAELEHHQRSHELRPQATRPPMPKVEAPSIRNSSPICESPPSRSRSPTVNVKQELYETDTVESGAGEDEPEENAQEDEEYIEVEQVPHETRPSELSSQLERSTSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00548267;
90% Identity: iTF_00488807;
80% Identity: -