Basic Information

Insect: Drosophila lacteicornis
Gene Symbol: L
Assembly: GCA_008044355.1
Location: VNKF01007965.1:116249-123820[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 9.3e-06 0.00076 19.9 2.9 1 23 162 184 162 184 0.98

2 17 0.14 12 6.7 7.3 1 23 190 212 190 212 0.97

3 17 1.5e-07 1.3e-05 25.5 3.2 1 23 218 240 218 240 0.99

4 17 1.1e-05 0.00093 19.6 0.4 1 23 246 268 246 268 0.99

5 17 0.011 0.91 10.2 0.2 2 23 343 367 342 367 0.92

6 17 0.0014 0.11 13.0 0.4 2 23 394 416 393 416 0.96

7 17 0.057 4.6 8.0 0.7 1 23 499 521 499 521 0.97

8 17 0.0038 0.31 11.6 0.1 2 23 529 550 528 550 0.92

9 17 2.8e-05 0.0023 18.3 0.2 1 23 558 583 558 583 0.94

10 17 4.6 3.7e+02 2.0 0.9 2 23 619 641 618 641 0.94

11 17 0.0023 0.19 12.3 1.1 1 23 690 713 690 713 0.97

12 17 0.0046 0.37 11.4 1.2 2 23 901 923 900 923 0.96

13 17 0.037 3 8.5 0.1 1 23 929 951 929 951 0.92

14 17 0.078 6.4 7.5 0.4 2 23 959 980 958 980 0.96

15 17 0.68 55 4.6 0.5 2 23 1081 1102 1081 1102 0.94

16 17 0.0088 0.72 10.5 0.0 1 23 1112 1134 1112 1134 0.96

17 17 0.00013 0.01 16.3 1.8 1 23 1141 1163 1141 1163 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	9.3e-06	0.00076	19.9	2.9	1	23	162	184	162	184	0.98
2	17	0.14	12	6.7	7.3	1	23	190	212	190	212	0.97
3	17	1.5e-07	1.3e-05	25.5	3.2	1	23	218	240	218	240	0.99
4	17	1.1e-05	0.00093	19.6	0.4	1	23	246	268	246	268	0.99
5	17	0.011	0.91	10.2	0.2	2	23	343	367	342	367	0.92
6	17	0.0014	0.11	13.0	0.4	2	23	394	416	393	416	0.96
7	17	0.057	4.6	8.0	0.7	1	23	499	521	499	521	0.97
8	17	0.0038	0.31	11.6	0.1	2	23	529	550	528	550	0.92
9	17	2.8e-05	0.0023	18.3	0.2	1	23	558	583	558	583	0.94
10	17	4.6	3.7e+02	2.0	0.9	2	23	619	641	618	641	0.94
11	17	0.0023	0.19	12.3	1.1	1	23	690	713	690	713	0.97
12	17	0.0046	0.37	11.4	1.2	2	23	901	923	900	923	0.96
13	17	0.037	3	8.5	0.1	1	23	929	951	929	951	0.92
14	17	0.078	6.4	7.5	0.4	2	23	959	980	958	980	0.96
15	17	0.68	55	4.6	0.5	2	23	1081	1102	1081	1102	0.94
16	17	0.0088	0.72	10.5	0.0	1	23	1112	1134	1112	1134	0.96
17	17	0.00013	0.01	16.3	1.8	1	23	1141	1163	1141	1163	0.97

Sequence Information

Coding Sequence: ATGATGGCCCTAAAGATGTTATATCGCGGTCCCAGTTCGCGTTTGgagaatttaattgaaaagatCCAGGCCACCAAGGAGATAACCAATAACGACATGTACAGTACCCACACATCGTCCAGTTACTCGCCTAGCATTTCGGATGGCACCATGACGCCCAATTCCCACCACTTGCCCGGAGCTCCActtgcagccgccgccgctggccaggaggatcatcatcatcactcCGGCGATGGCAAGGTTAATGGTGGCCTTGATGgcgaggagctggccaagccCAAGAGGCTGCCCCACttccatcaccatcatcatcatcattaccACCATCAGCAGGCGCTGAAAATCGCCCAGAAGCTGCGCAAAATCAATAAGGAAGCCAAAATGGGAGCTGGCGGCGGCGCTGGAGGAGCCGGTGGAGGAGCAGCCTCCAAGTTTGATAAGTTGACAGGAGAGGGCATTAAGGCACGCGGCGACGGCTCCTATCAGTGTCAGTTCTGCGACAAGTCATTTCCACGTCTCGGCTACTTGAAGCATCACGTGCAGAGCCACGCCGAACACCTGCCCTTCAAGTGCGAATACTGCTCGAAGCTGTTCAAGCACAAGCGATCCCGGGATCGCCACAAGAAGCTGCATACCAACGAGCGCAACTACAAGTGTCCCCATTGCGAGGCGGCCTTCTCCAGGAGTGACCACCTGAAGATCCACATGAAGACGCACGACATCCAGAAGCCGTTCCAGTGCAGCATGTGCAACCGGGGCTATAATACGGCGGCCGCTTTGACCTCGCACATGCAGAAGCACAAGAAGAATGCGGCCATCCTGGCAGCTGGCGGCAATCCCAATGCCCTGAACTATAGTCCCCGATCCACGGgctcggcctcggcctcggtGTCCAGCAATGGCAGTCTGCAGAAGAGGCGTTATGCCCTGGCCTTGGCCTCGGACAGTAGTCCCAGTCGCCTGGATTTCCCAAAGAGATCGAGGAGCGGCACCACCGCGGCAGCCACACCCACGCCCCTGCTCAGATGTAGCTACTGTCCCAAGGTCACGGAGTTTAGCAGCCTGGAGCAGCTCAATGCCCACCTCCAGAGTGtccacgagcagcagcagcagcagcagcagcaggcgacGCCAGCCAAGACCCCTGTAACCCAAGAGAGCGAGGGCTTCCAGCTGAGCTGCGAGTACTGCACCATGAAGTTTGGCAACATTGCCGGTCTGTTCCAGCACATGCGGAGCACGCACCTGGACAGGCTGAGCAGCCCCAACTCCTACTACGAGCACTTCAATCGCCTGGCCACCGCCGGCACTTTTAGTCCCCGCCTGGCCCTGGACTTGCCCAAAATCAAGCAGGACTTGGGCAGCCCCGAAAGGGAGACCCAGAGAGCTGCAGAGGAGGATTTGCCCACCGATTTGAGCAGCAACAAGAGGGGGCGCCCGCAGACCCCGAATCCCCAGCAACTGGCAccaccagctgctcctcccGGGGTCTTCTTCTGCAATCAGTGCAACGCAGGACTCCCAGACTTTGAGAGCTTCAGGAATCACCTGAAGAGCCACATCGCCGAGGGCATGCACATGGTGTGTCCGCATTGCGGGCTGAGTCTCCCCGAGCAGTCCGAGTTCGAGCGCCATGTGGTGGGCCACTTCCTCATCACCGGCTCCGAGTTCAACTGCAGCGGCTCCGGCTGCGGCAAGAGCTTCGCCAAGTCCGAGGacctgcagcagcacctgCTTTCGGAGCACGTGCTCACCCTGCTCAAGTGTTCGCTGTGCTCGGAGCTCTGCGAGAGCCGGATGGCCATGCAGCTGCACCTGGCCTGTGCCCACAGCCAGGAGACGAAGCTGCTGAGGTGCAGCGCCTGCCTGGAGCTCTTCCGCTCCGACGCGGAGTTCCATGTGCATGTGAAGACGCGCCACCAGCTGGTGGGGGGTCATCCATCGCTGGGCGTCGGGGCCACCACACCGAGTGCTCCCTCGAATCCGCTGCAGTGCATGTTCTGCCGGGCTGTCTGTTCCTCGGAGCTGGAGATGCACTTCCATCTGGCGGCGCACGCCAGGCAGTTCCGCTGCCCCTCCTGCCCGGAGACCTTCCACGTGGAGTTCCTGCTGGACCGGCACATGCAGAGCCAGCACGGGGGAGGAGTCAAGGAgagcaaggagcagcagcggggcTCGCCGAACATGGGCAGcctctatgtgaatgccctgctgcctcctctggcggcagcggcggcggcagcagcggccaccaacaacaatagcagcaTCATCGACTACAATGTAGCCTTCAAGGGCTTATTCGGAGGAGGAGCTACTTCTGGAGCAGGTTCGGGATCAGGAGGAGGCTCTGGAGGAGCACCCCCCTCGGGAAACAAGTTCTACAGCCCGCTGCAGGTGGACACCAATGCCCTGAAGGCCCAGACCTCGCCGCATCCCGCCCTCATGTACGGCCTGAGCCAGCGCTATCTGATGGAGATGTACGCCGCCAAGTCCACCTCCCCGGCGGGCAACGAGGGCAACCCACAGGCGCCACCGCCACAGGCTCCCCAGCCCCCAGCTCCTCAGCCACCGAGCTCTGCCGCGTCGGGGGCCACCTTCAGCTGTGGGATGTGCGAGCGCCAGGATCTGCGCAGCGAGGCGGAGCTCCACTCGCACCGCAAGCTGGCCCACAACCTCAAGACCGGGGTGAGCCTGAGGTGTGCCTACTGTGCCGGGAACTTCAAGTCCCGGgccgagctggagcagcacaTGAAGAGCTGCCACAATTCGACGGGCAAGCACAAGTGCCTGATCTGCGATGAGGTCTTCCCCTCGCCGGCCATCCTGGCCGAGCACAAGCTGCAGCACTCCAAGGTGGGTCAGTCCGGCAAGTGCTCTCACTGCGGTCATCCCTTGGAGGATGTGGCCGCCTTCAGGGCTCATCTCTCAGAGCATGGGAGTGATGGGGCCACCTTGCCGCTGGCCTGCATCTGCTGTCGCCAGACCCTGCACTCGGAGTTCGAGCTGAGCCTGCACGCCAAGTTCCACACCAAGTCGGCCTCGAGCGGCGGTAGCCTGCAGGAGCCGGTGTGTGCTCTGTGCCTAGAGCCACTGCCAGATGTGCCCTTGGAGGGTCCGGCCAAGCTCTGCGAGAAGTGCTGCCGGAAGCACAACTTAAACGGGAAGCGGGGCAAGCCAAGTGATCCTCCGCTGCAGGCCCCGCCATCATCAGCACCTTCTGCCTTCGTGGAGAACCGCTGCAACCTGTGCAAGATGATCCTCCCCCATGCCCAGAAGCTCCAGGAACACCTGGTGGAGCACACGTTCGCGGGCACCGAGCAGCGCGGCTTCAACTGCTACATCTGCTCGGCGGTCTTTACGGCCCCAGGAGGCCTGCTCAATCACATGGCCGAGCATGGAGCCCACTCGCGGCCCTACGACTGCAGCCTGTGTCCGGAGAAGTTCTACTTCCGGTCCGAGTTGGAGCACCACCAAAGGGGTCACGAGCTGAGGCCACAGGCGGCAACAACGAGGCCAAGTATGCCCAAGGTGGAGCCAGCCTCCTCCATCCGCAACAGTTCTCCGCTTTGTGAGAGTCCTCCTTCGAGGAGTCGGAGTCCTACGATTGTCAAGCAGGAACTCTACGAAACAGACACAGTGGAGTCCGGTGCAGGAGAGGATGAGCCAGAGGAGAACGCCCCCGAAGATGAGGAGTACATCGAGGTAGAGCAGGTCCCACATGAGACGCGACCAAGTGAGATGGGTTCGCAAATGGAAAGGTCCACCAGTAGCGCCTAA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEITNNDMYSTHTSSSYSPSISDGTMTPNSHHLPGAPLAAAAAGQEDHHHHSGDGKVNGGLDGEELAKPKRLPHFHHHHHHHYHHQQALKIAQKLRKINKEAKMGAGGGAGGAGGGAASKFDKLTGEGIKARGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCSKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASASVSSNGSLQKRRYALALASDSSPSRLDFPKRSRSGTTAAATPTPLLRCSYCPKVTEFSSLEQLNAHLQSVHEQQQQQQQQATPAKTPVTQESEGFQLSCEYCTMKFGNIAGLFQHMRSTHLDRLSSPNSYYEHFNRLATAGTFSPRLALDLPKIKQDLGSPERETQRAAEEDLPTDLSSNKRGRPQTPNPQQLAPPAAPPGVFFCNQCNAGLPDFESFRNHLKSHIAEGMHMVCPHCGLSLPEQSEFERHVVGHFLITGSEFNCSGSGCGKSFAKSEDLQQHLLSEHVLTLLKCSLCSELCESRMAMQLHLACAHSQETKLLRCSACLELFRSDAEFHVHVKTRHQLVGGHPSLGVGATTPSAPSNPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGGVKESKEQQRGSPNMGSLYVNALLPPLAAAAAAAAATNNNSSIIDYNVAFKGLFGGGATSGAGSGSGGGSGGAPPSGNKFYSPLQVDTNALKAQTSPHPALMYGLSQRYLMEMYAAKSTSPAGNEGNPQAPPPQAPQPPAPQPPSSAASGATFSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCAGNFKSRAELEQHMKSCHNSTGKHKCLICDEVFPSPAILAEHKLQHSKVGQSGKCSHCGHPLEDVAAFRAHLSEHGSDGATLPLACICCRQTLHSEFELSLHAKFHTKSASSGGSLQEPVCALCLEPLPDVPLEGPAKLCEKCCRKHNLNGKRGKPSDPPLQAPPSSAPSAFVENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPGGLLNHMAEHGAHSRPYDCSLCPEKFYFRSELEHHQRGHELRPQAATTRPSMPKVEPASSIRNSSPLCESPPSRSRSPTIVKQELYETDTVESGAGEDEPEENAPEDEEYIEVEQVPHETRPSEMGSQMERSTSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00548267;
90% Identity: iTF_00488807;
80% Identity: -