Basic Information

Insect: Drosophila monieri
Gene Symbol: L
Assembly: GCA_035047585.1
Location: JAWNPJ010000082.1:2638812-2644986[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 3.3e-05 0.0026 18.2 2.9 1 23 156 178 156 178 0.98

2 17 0.15 12 6.7 7.3 1 23 184 206 184 206 0.97

3 17 1.6e-07 1.3e-05 25.5 3.2 1 23 212 234 212 234 0.99

4 17 1.2e-05 0.00093 19.6 0.4 1 23 240 262 240 262 0.99

5 17 0.011 0.91 10.2 0.2 2 23 344 368 343 368 0.92

6 17 0.0014 0.11 13.1 0.4 2 23 389 411 388 411 0.96

7 17 0.058 4.6 8.0 0.7 1 23 490 512 490 512 0.97

8 17 0.0041 0.33 11.6 0.1 2 23 520 541 519 541 0.92

9 17 4e-05 0.0032 17.9 0.5 1 23 549 573 549 573 0.95

10 17 4.7 3.7e+02 2.0 0.9 2 23 609 631 608 631 0.94

11 17 0.0024 0.19 12.3 1.1 1 23 677 700 677 700 0.97

12 17 0.0047 0.37 11.4 1.2 2 23 887 909 886 909 0.96

13 17 0.038 3 8.6 0.1 1 23 915 937 915 937 0.92

14 17 0.046 3.6 8.3 0.1 2 23 945 966 944 966 0.96

15 17 0.7 56 4.6 0.5 2 23 1070 1091 1070 1091 0.94

16 17 0.016 1.2 9.8 0.0 1 23 1101 1123 1101 1123 0.96

17 17 0.00022 0.017 15.6 1.2 1 23 1130 1152 1130 1152 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	3.3e-05	0.0026	18.2	2.9	1	23	156	178	156	178	0.98
2	17	0.15	12	6.7	7.3	1	23	184	206	184	206	0.97
3	17	1.6e-07	1.3e-05	25.5	3.2	1	23	212	234	212	234	0.99
4	17	1.2e-05	0.00093	19.6	0.4	1	23	240	262	240	262	0.99
5	17	0.011	0.91	10.2	0.2	2	23	344	368	343	368	0.92
6	17	0.0014	0.11	13.1	0.4	2	23	389	411	388	411	0.96
7	17	0.058	4.6	8.0	0.7	1	23	490	512	490	512	0.97
8	17	0.0041	0.33	11.6	0.1	2	23	520	541	519	541	0.92
9	17	4e-05	0.0032	17.9	0.5	1	23	549	573	549	573	0.95
10	17	4.7	3.7e+02	2.0	0.9	2	23	609	631	608	631	0.94
11	17	0.0024	0.19	12.3	1.1	1	23	677	700	677	700	0.97
12	17	0.0047	0.37	11.4	1.2	2	23	887	909	886	909	0.96
13	17	0.038	3	8.6	0.1	1	23	915	937	915	937	0.92
14	17	0.046	3.6	8.3	0.1	2	23	945	966	944	966	0.96
15	17	0.7	56	4.6	0.5	2	23	1070	1091	1070	1091	0.94
16	17	0.016	1.2	9.8	0.0	1	23	1101	1123	1101	1123	0.96
17	17	0.00022	0.017	15.6	1.2	1	23	1130	1152	1130	1152	0.97

Sequence Information

Coding Sequence: ATGATGGCCCTAAAGATGTTATACCGCGGTCCCAGTTCGCGTTTAgagaatttaattgaaaagatCCAGGCCACCAAGGAGATAACCAATAACGATATGTACAGCACTCACACATCGTCCAGCTACTCGCCCAGCATTTCGGACGGCACCATGACTCCCAACTCACACCACTTGCCGGGAGCTCCGGCCAGCCTCCCTGGCCAGGACCAGGATCATCCCAGAGAGGCAAGCACCAATGGCGGGCTGGATGGCGAGGACTTGGTTAAGCCGAAGCGTCTGCCCCActttcatcatcatcaccaccaccactatcACCACCAGCAGGCGCTGAAAATCGCCAACAAGCTGCGGAAAATCAATAAGGAAGCCAAGCTGGGAGCCTtgggaggagcaggagccggagGAGCTGGCTCCAAGTTTGATAAGTTGACGGGCGAGGGGATTAAAAGTCGCGGCGACGGCTCCTATCAGTGTCAGTTCTGCGAAAAGTCATTTCCGCGTCTCGGTTACTTGAAGCATCACGTGCAGAGCCACGCCGAACACCTGCCCTTCAAGTGCGAGTACTGCTCCAAGCTCTTCAAGCACAAGCGCTCCCGGGATCGCCATAAGAAGTTGCACACCAACGAAAGGAACTACAAGTGTCCCCACTGCGAGGCGGCATTCTCCAGGAGTGACCATCTTAAGATCCACATGAAAACCCATGACATCCAGAAGCCCTTCCAGTGCAGCATGTGCAACAGGGGCTACAACACGGCGGCTGCCCTGACCTCCCACATGCAGAAGCACAAGAAGAACGCCGCTATCCTGGCAGCTGGAGGCAACCCCAATGCCTTGAACTACAGTCCCCGCTCCACGGGATCGGCCTCTGCTTCGGTTTCCAGCAACGGGAGCCTGCACAAGAGGCGGTATGCCCTGGCCCTGGCCACGGACAGCAGTCCCAGCCGTCTGGACTACCCCCAGAAGAGATCGAGAAgtggcaccaccaccactgccgccgccacagcaaatgccacgcccacgcccctGCTGAGGTGCAGCTACTGCCCCAAGGTGACGGAGTTCAGCAGCCTGGAGCAGTTAAATGCCCACTTGCAGAGTGTCCACGAGCAGCCCCAGCAGCCGCCGGTGAAGACTCCCAGCCAGGAGGCCGAGGGCTTTCAGCTGAGCTGCGAGTACTGCACCATGAAGTTCGGCAACATAGCCGGCCTCTTCCAGCACATGCGGAGCACTCACCTGGATAGGCTGAGCAGCCCGAACTCCTACTACGAACACTTCAACCGCCTGGCCACCGCCGGCACCTTCAGCCCGCGCCTGGCCCTGGATCTGCCCAAGATCAAGCCGGACTTGGGAAGTCCCGATCAACGGGAGCTGCGGCCGGCAGAGGAGGACCTGCCCACAGACTTGAGCAGTAACAAGCGGCGACCCCTGACCCCGAACCCGCAGCCACCACCAGCTCCGCCGGGCGTCTTCTTCTGCAATCAGTGCAACGCTGGCTTGCCGGACTTCGAGAGCTTCAGGAATCACCTGAAGAGCCACATCGCCGAGGGAATGCAGCAGGTCTGTCCGCACTGTGGACTCAGCCTGCCGGAGCAGTCGGAGTTCGAGCGCCATGTGGTGGGCCACTTCCTGATCACGGGATCCGAGTTCAACTGCAGCTCCAGCTGCGGAAAGAGCTTCGCCAAGTCGGAGGACCTCCAACAGCACCTCCTCACCGAGCACGTCCTCACTCTCCTGAAGTGCTCCCTGTGCTCGGAGCTGTGCGAGAGCCGGATGGCCATGCAGCTCCACCTGGCCTGTGCCCACAGCCAGGAGACCAAGCTGCTGCGGTGCAGTGCCTGCCTGGAGCTGTTCCGCTCTGATGCCGAGTTCCATGTTCACGTGAAGACGCGCCACCAGCTGGGCGGACATCCGGCCCTGGGCAGTGCCACTGCGAACACCCCCTCCAATCCTCTCCAGTGCATGTTTTGCCGAGTGGTCTGCTCCTCGGAGCTGGAGATGCACTTCCACTTGGCGGCCCACGCCCGGCAGTTCCGGTGTCCCTCGTGCCCCGAGACCTTCCACGTCGAGTTCCTCCTTGACCGTCACATGCAGAGCCAGCACGGCGGAGGAGCAGGCGTAAAGGACAAGGAGGCCAGTTCGCCCAACATGGGCAGCCTGTACGTGAACGCCTTGCTGCCACCActggcggcagcggcagcggcggcagcagccaccaacaacaacagcagcatcaTCGACTACAACGTGGCGTTCAAGGGACTGTTTGGCGGAGCAGCCGGAGGCGGGGGAGGAGGGTCGGGAGCACCCACTGCCCCCTCGTCGAAGTTCTACAGCCCGCTGCAGGTGGACACCAATGCCCTGAAGGCACAGACCTCGCCCCACCCGGCCCTGATGTACGGGCTGAGTCAGCGGTACTTGATGGAAATGTACGCCGCCAAGTCGGCCTCTCCGCCGGGAAGCGAGGGCGGAGCCAGTGGCCAGGCAGTCGGTGGTCAGGCAGCCGTGGCAGCACCACCGCCACCCCCTCCTCCGGCACCCCAGCAGGCAGCACCCACCACCTTCAGTTGCGGGATGTGCGAGAGACAGGATCTGAGGAGCGAGGCGGAACTCCACTCGCACCGCAAACTGGCCCACAACCTGAAGACCGGCGTGAGCCTGAGGTGCGCCTACTGCGCCGGGAACTTCAAGTCCCGGGCGGAGCTGGAGCAGCACATGAAGAGCTGCCACAACTCCACGGGCAAGCACAAGTGCTTGATCTGCGACGAGGTGTTCCCCTCGCCGGCCATCCTAGCGGAGCACAAGCTGCAGCACTCCAAGGTGGGTCAGTCGGGCAAGTGCTCGCACTGCGGCCAGCCCCTGGAGGACGTGGCGGCCTTCCGGGCCCACCTCTCCGAGCACGGCAGTGACGGGGCCTCCCTGCCCCTGGCCTGCATCTGCTGCCGCCAGACCCTGCATTCGGAGTTCGAGCTGAGTCTGCACGCCAAGTTCCACACCAAGTCCGCCTCCAGTGGTGGTAGCCTGCAGGAGCCAGTGTGTGCCCTGTGCCTGGAGCCCCTGCCGGACGCCACCGAGGGTCCTGCCAAGCTCTGCGAGAAGTGCTGCCGGAAGCACAACCTCAATGGGAAGAGGAGCAAGCCGCCGAGTGAGCCGCCAGTCCAGAGTCTGCAGCCAATCCAGCCACCATCCGGGGCAGCCTTCGTGGAGAACCGATGCAACCTGTGCAAGATGATCCTGCCGCACGCCCAGAAGCTGCAGGAGCACCTGGTGGAGCACACCTTTGCCGGCACCGAGCAGCGCGGCTACAATTGCTACATCTGCTCCGCGGTCTTCACGGCTGCCGGTGGCCTCCTCAACCACATGGCGGATCATGGCGCCCACACGCGTCCCTACGACTGCAACCTCTGCCCGGAGAAGTTCTACTTCCGGGCGGAGCTGGAGCACCACCAGCGGGGCCACGAGCTGCGGCCCCAGGCACGTCCCAAGGTGGAAGTGCCCTCGAACAGGACCAGTTCCTCGCCCATCGACAGCCCCGTGAGGAGTCCCACGATCGTCAAGCAGGAGCTGTACGAGACGGATACGGCCCAGTCGGCCGGAGGGGACGAGGACGAGCCGGAAAACGCGCACGAGGACGAGGAGTACATCGAGGTAGAGCAGATGCCGCACGAGGGGCGTCCCAGTGACTTGGAAAGGGCAACCAGTAGCGCCTAG
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEITNNDMYSTHTSSSYSPSISDGTMTPNSHHLPGAPASLPGQDQDHPREASTNGGLDGEDLVKPKRLPHFHHHHHHHYHHQQALKIANKLRKINKEAKLGALGGAGAGGAGSKFDKLTGEGIKSRGDGSYQCQFCEKSFPRLGYLKHHVQSHAEHLPFKCEYCSKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASASVSSNGSLHKRRYALALATDSSPSRLDYPQKRSRSGTTTTAAATANATPTPLLRCSYCPKVTEFSSLEQLNAHLQSVHEQPQQPPVKTPSQEAEGFQLSCEYCTMKFGNIAGLFQHMRSTHLDRLSSPNSYYEHFNRLATAGTFSPRLALDLPKIKPDLGSPDQRELRPAEEDLPTDLSSNKRRPLTPNPQPPPAPPGVFFCNQCNAGLPDFESFRNHLKSHIAEGMQQVCPHCGLSLPEQSEFERHVVGHFLITGSEFNCSSSCGKSFAKSEDLQQHLLTEHVLTLLKCSLCSELCESRMAMQLHLACAHSQETKLLRCSACLELFRSDAEFHVHVKTRHQLGGHPALGSATANTPSNPLQCMFCRVVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGGAGVKDKEASSPNMGSLYVNALLPPLAAAAAAAAATNNNSSIIDYNVAFKGLFGGAAGGGGGGSGAPTAPSSKFYSPLQVDTNALKAQTSPHPALMYGLSQRYLMEMYAAKSASPPGSEGGASGQAVGGQAAVAAPPPPPPPAPQQAAPTTFSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCAGNFKSRAELEQHMKSCHNSTGKHKCLICDEVFPSPAILAEHKLQHSKVGQSGKCSHCGQPLEDVAAFRAHLSEHGSDGASLPLACICCRQTLHSEFELSLHAKFHTKSASSGGSLQEPVCALCLEPLPDATEGPAKLCEKCCRKHNLNGKRSKPPSEPPVQSLQPIQPPSGAAFVENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGYNCYICSAVFTAAGGLLNHMADHGAHTRPYDCNLCPEKFYFRAELEHHQRGHELRPQARPKVEVPSNRTSSSPIDSPVRSPTIVKQELYETDTAQSAGGDEDEPENAHEDEEYIEVEQMPHEGRPSDLERATSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00548267;
90% Identity: iTF_00615690;
80% Identity: -