Basic Information

Insect: Drosophila kurseongensis
Gene Symbol: L
Assembly: GCA_018153305.1
Location: JAECXX010000004.1:18441610-18448361[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 3.9e-05 0.0029 17.9 3.0 1 23 155 177 155 177 0.98

2 18 0.14 10 6.8 7.3 1 23 183 205 183 205 0.97

3 18 1.5e-07 1.1e-05 25.5 3.2 1 23 211 233 211 233 0.99

4 18 1.1e-05 0.00083 19.6 0.4 1 23 239 261 239 261 0.99

5 18 0.011 0.81 10.2 0.2 2 23 340 364 339 364 0.92

6 18 0.0014 0.1 13.1 0.4 2 23 383 405 382 405 0.96

7 18 0.056 4.1 8.0 0.7 1 23 489 511 489 511 0.97

8 18 0.0032 0.23 11.9 0.1 2 23 519 540 518 540 0.91

9 18 8.4e-05 0.0062 16.9 0.4 1 23 548 572 548 572 0.94

10 18 1.6 1.2e+02 3.4 0.2 2 20 578 596 577 597 0.93

11 18 4.5 3.3e+02 2.0 0.9 2 23 608 630 607 630 0.94

12 18 0.0023 0.17 12.4 1.1 1 23 675 698 675 698 0.97

13 18 0.0045 0.33 11.4 1.2 2 23 875 897 874 897 0.96

14 18 0.036 2.7 8.6 0.1 1 23 903 925 903 925 0.92

15 18 0.044 3.2 8.3 0.1 2 23 933 954 932 954 0.96

16 18 0.67 49 4.6 0.5 2 23 1052 1073 1052 1073 0.94

17 18 0.0087 0.64 10.5 0.0 1 23 1083 1105 1083 1105 0.96

18 18 0.00015 0.011 16.0 1.7 1 23 1112 1134 1112 1134 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	3.9e-05	0.0029	17.9	3.0	1	23	155	177	155	177	0.98
2	18	0.14	10	6.8	7.3	1	23	183	205	183	205	0.97
3	18	1.5e-07	1.1e-05	25.5	3.2	1	23	211	233	211	233	0.99
4	18	1.1e-05	0.00083	19.6	0.4	1	23	239	261	239	261	0.99
5	18	0.011	0.81	10.2	0.2	2	23	340	364	339	364	0.92
6	18	0.0014	0.1	13.1	0.4	2	23	383	405	382	405	0.96
7	18	0.056	4.1	8.0	0.7	1	23	489	511	489	511	0.97
8	18	0.0032	0.23	11.9	0.1	2	23	519	540	518	540	0.91
9	18	8.4e-05	0.0062	16.9	0.4	1	23	548	572	548	572	0.94
10	18	1.6	1.2e+02	3.4	0.2	2	20	578	596	577	597	0.93
11	18	4.5	3.3e+02	2.0	0.9	2	23	608	630	607	630	0.94
12	18	0.0023	0.17	12.4	1.1	1	23	675	698	675	698	0.97
13	18	0.0045	0.33	11.4	1.2	2	23	875	897	874	897	0.96
14	18	0.036	2.7	8.6	0.1	1	23	903	925	903	925	0.92
15	18	0.044	3.2	8.3	0.1	2	23	933	954	932	954	0.96
16	18	0.67	49	4.6	0.5	2	23	1052	1073	1052	1073	0.94
17	18	0.0087	0.64	10.5	0.0	1	23	1083	1105	1083	1105	0.96
18	18	0.00015	0.011	16.0	1.7	1	23	1112	1134	1112	1134	0.98

Sequence Information

Coding Sequence: ATGATGGCCCTAAAGATGTTATATCGTGGTCCCAGTTCGCGTTTGGAGAATTTAATCGAAAAGATTCAGGCCACCAAGGAGATAACCAATAACGATATGTACAGTACACACACATCCTCCAGTTATTCTCCTAGTATTTCCGATGGTACCATGACACCTAACTCACACCACTTGCCCGGAGCTCCAACCGCAGCTGGTGGTCAAGAGGATCATCCGGCTGAAGGCAAGGCCAATGGTGGCGCCGATGGCGAGGAGTTGCCCAAGCCAAAACGCTTGCCTCACTTCCATCACCATCACCACCATCACTACCACCATCAACAGGCGCTGAAAATAGCCAACAAGTTGCGCAAAATCAATAAGGAAGCCAAAATGGGAGCTACTGCGGGTGCGGGATCCACTGGAGCAGCCGCCAAGTTTGATAAGTTGACAGGAGAGGGGATTAAAAGTCGCGGCGACGGCTCCTATCAGTGTCAGTTCTGCGAAAAGACATTTCCACGTCTCGGCTACTTGAAGCATCACGTACAGAGCCACGCTGAACACCTGCCTTTCAAATGTGAGTACTGCTCCAAGCTTTTCAAACACAAGCGTTCCCGTGATCGTCATAAGAAATTGCATACCAACGAGCGGAATTACAAGTGTCCACATTGCGAGGCTGCTTTTTCGAGGAGTGACCATTTGAAGATCCATATGAAGACCCATGACATCCAGAAGCCCTTCCAGTGTAGTATGTGTAACAGGGGCTATAATACAGCTGCTGCTTTAACATCTCACATGCAAAAGCACAAGAAGAACGCAGCTATCTTGGCAGCCGGTGGCAATCCCAATGCCCTGAACTATAGTCCTCGATCCACGGGATCTGCCTCGGCATCGGTTTCCAGCAATGGTAGTCTACAGAAGAGGAGATATGCCTTGGCCCTGGCTTCAGATAGTAGTCCCAGTAGATTGGATTTCCCCAAGAGATCGAGAAGTAGTCATGTGGGTGGCACTACCACCACCGCCACGCCCACTCCCCTGCTGAGGTGCAGCTACTGCCCCAAGGTCACAGAGTTCAGTAGTCTGGAGCAGCTGAATGCCCATCTTCAGAGTGTCCATGAGCAACAACAGGCTGTGAAGACTCCGGTTCAGGAGGGCGAAGGCTTTCAGCTGAGCTGTGAGTACTGCACCATGAAGTTTGGCAATATCGCCGGACTCTTCCAGCACATGAGGAGCACCCACATGGACAGGTTGAGCAGCCCGAACTCCTACTACGAGCACTTCAATCGTTTGGCCACCGCCGGTACATTCAGTCCACGTCTTGCTTTGGACATGCCCAAAATTAAACCGGATTTGGGAAGTCCGGAAAGGGAATCGCGACCAGCAGAGGACGATCTTCCCACGGATTTGAGCAGCAACAAGAGGCGACCGATGACACCCAACCCTCAAACGCACACTCAACTGGCACCACCCGCTGGTCCACCAGGGGTATTCTTCTGCAATCAGTGCAACGCAGGACTACCGGATTTCGAGAGCTTCAGGAATCATCTGAAGAGTCACATTGCCGAGGGCATGCAGCTGGTTTGTCCTCATTGCGGTCTGAGTTTGCCAGAGCAATCGGAGTTCGAGCGTCATGTGGTGGGTCACTTCCTCATCACGGGCTCGGAATTCAACTGTAGTTCCAGCTGCGGAAAGAGTTTTGCCAAATCGGAGGATCTGCAGCAACATTTGCTTTCCGAGCACGTGCTAACCCTTCTGAAGTGTTCCTTGTGTTCGGAGGTGTGTGAGAGTCGGATGGCCATGCAGCTCCATTTGGCCTGTGCCCACAGTCAGGAAACGAAACTCCTCCGCTGCAGCGCCTGTTTGGAGCTCTTCCGATCCGATGCCGAGTTCCATGTGCATGTCAAGACACGTCATCAGTTGGGCGGACATCCCACGTTGGGCGCCAATTCCAGTGCCCCCACTAATCCTCTGCAGTGTATGTTTTGCCGAGCAGTTTGCTCCTCCGAGTTGGAGATGCATTTCCATTTGGCCGCCCACGCCCGTCAGTTTAGATGTCCCTCCTGCCCGGAGACCTTCCACGTGGAGTTCTTGCTGGATCGTCATATGCAGAGTCAGCATGGCGGAGTCAAGGACAAGGAGGCGAACTCGCCCAATATGGGCAGTCTCTATNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTACAATGTGGCATTCAAGGGCCTGTTCGGAGGAGCGGCTGGGGGAGCAGGAGCTCAAGCACCCGGAGGAGCACCCCCCTCGAGCAACAAGTTCTACAGTCCCCTACAAGTGGACACCAATGCATTAAAACCCCAAACCTCTCCTCACCCGGCCTTAATGTACGGTCTAAGTCAACGATATCTGATGGAGATGTATGCCGCCAAGTCCACATCGCCCTCGGGAAATGAGGGTGTTGGAAATCCACAGCCGACGGCTCCTCAGGCCACCGCACCACCACCATCTAATGCAAATACTGCCACCTTCAGTTGCGGAATGTGCGAGCGACAGGATTTGCGCAGCGAAGCGGAACTCCACTCCCATCGCAAACTGGCCCACAATCTGAAGACGGGAGTGAGTTTGAGATGTGCCTACTGTGCGGGAAATTTCAAATCTCGAGCCGAACTGGAGCAGCACATGAAGAGCTGTCACAATTCGACGGGCAAACACAAGTGTCTGATATGCGATGAGGTATTTCCCTCACCGGCCATTCTGGCCGAGCATAAGTTGCAGCACTCGAAGGTGGGGCAGTCTGGAAAGTGCTCCCACTGTGGCCAGCCTCTGGAGGATGTGGCTGCATTCAGAGCTCATCTGTCGGAACATGGAAGCGATGGAGCCTCCTTGCCACTAGCCTGCATTTGCTGCCGCCAAACGTTGCACTCGGAATTCGAGCTAAGTCTGCATGCCAAATTCCACACCAAGTCCTCCTCGAGCGGTGGTAGTCTGCAGGAACCAGTGTGTGCTCTGTGCCTGGAACCTCTACCCGATGCCGTCGAGGGTCCAGCGAAGCTCTGCGACAAGTGCTGCCGTAAACATAACTTGAATGGAAAACGGGGCAAACACAGTGAGGCACCCACATCTCTGCAAGCACCGCCCTCGGCATTTGTGGAGAATCGCTGCAACCTGTGCAAGATGATCCTGCCACATGCCCAAAAGCTGCAGGAACATCTGGTGGAACACACCTTCGCGGGCACCGAACAGCGTGGCTTCAATTGCTACATATGCTCGGCCGTCTTCACCGCACCCGGTGGTCTACTCAACCACATGGCAGAGCATGGAGCTCATTCGCGACCCTACGATTGCAGTCTCTGCCCCGAGAAATTCTACTTCCGAGCCGAGTTGGAACACCACCAAAGGAGCCATGAGTTGAGACCACAGGCACGTCCGCCAGTATCAAAAGTGGAGGTACCTTCCAACCGGAACAATTCGCCCACCCAGAGTCCAGAGCGAAGTCCCACGATTGTCAAACAGGAGCTATACGAAACGGATACGGTTGAGTCCGCTGGAGGAGAAGAGGAGCCGGAGAATCCACCAGACGAAGAGGAGTACATTGAAGTCGAGCAAATGCCACATGAGACACGTCCAAGTGAGATTGGGTCGCAAATGGAAAGGTCCACCAGCAGCGCCTAA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEITNNDMYSTHTSSSYSPSISDGTMTPNSHHLPGAPTAAGGQEDHPAEGKANGGADGEELPKPKRLPHFHHHHHHHYHHQQALKIANKLRKINKEAKMGATAGAGSTGAAAKFDKLTGEGIKSRGDGSYQCQFCEKTFPRLGYLKHHVQSHAEHLPFKCEYCSKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASASVSSNGSLQKRRYALALASDSSPSRLDFPKRSRSSHVGGTTTTATPTPLLRCSYCPKVTEFSSLEQLNAHLQSVHEQQQAVKTPVQEGEGFQLSCEYCTMKFGNIAGLFQHMRSTHMDRLSSPNSYYEHFNRLATAGTFSPRLALDMPKIKPDLGSPERESRPAEDDLPTDLSSNKRRPMTPNPQTHTQLAPPAGPPGVFFCNQCNAGLPDFESFRNHLKSHIAEGMQLVCPHCGLSLPEQSEFERHVVGHFLITGSEFNCSSSCGKSFAKSEDLQQHLLSEHVLTLLKCSLCSEVCESRMAMQLHLACAHSQETKLLRCSACLELFRSDAEFHVHVKTRHQLGGHPTLGANSSAPTNPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGVKDKEANSPNMGSLYXXXXXXXXXXXXXXXXXXXXXXXXXXYNVAFKGLFGGAAGGAGAQAPGGAPPSSNKFYSPLQVDTNALKPQTSPHPALMYGLSQRYLMEMYAAKSTSPSGNEGVGNPQPTAPQATAPPPSNANTATFSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCAGNFKSRAELEQHMKSCHNSTGKHKCLICDEVFPSPAILAEHKLQHSKVGQSGKCSHCGQPLEDVAAFRAHLSEHGSDGASLPLACICCRQTLHSEFELSLHAKFHTKSSSSGGSLQEPVCALCLEPLPDAVEGPAKLCDKCCRKHNLNGKRGKHSEAPTSLQAPPSAFVENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPGGLLNHMAEHGAHSRPYDCSLCPEKFYFRAELEHHQRSHELRPQARPPVSKVEVPSNRNNSPTQSPERSPTIVKQELYETDTVESAGGEEEPENPPDEEEYIEVEQMPHETRPSEIGSQMERSTSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00548267;
90% Identity: iTF_00504840;
80% Identity: -