Basic Information

Insect: Drosophila subobscura
Gene Symbol: L
Assembly: GCA_008121235.1
Location: NC:9496841-9524166[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 1.2e-05 0.00073 19.4 3.1 1 23 312 334 312 334 0.98

2 18 0.34 20 5.4 6.2 1 23 340 362 340 362 0.97

3 18 1.7e-07 9.9e-06 25.3 3.2 1 23 368 390 368 390 0.99

4 18 1.2e-05 0.00073 19.4 0.4 1 23 396 418 396 418 0.99

5 18 0.012 0.71 10.0 0.2 2 23 491 515 490 515 0.92

6 18 0.0038 0.22 11.6 0.2 2 23 543 565 542 565 0.95

7 18 0.061 3.6 7.8 0.7 1 23 648 670 648 670 0.97

8 18 0.003 0.18 11.9 0.1 2 23 678 699 677 699 0.91

9 18 0.0025 0.15 12.2 0.1 1 23 707 731 707 731 0.90

10 18 3.5 2.1e+02 2.3 0.1 2 20 737 755 736 756 0.92

11 18 1.3 76 3.6 0.9 2 23 767 789 766 789 0.95

12 18 0.0025 0.15 12.2 1.1 1 23 842 865 842 865 0.97

13 18 0.0049 0.29 11.2 1.2 2 23 1043 1065 1042 1065 0.96

14 18 0.11 6.7 7.0 0.1 1 23 1071 1093 1071 1093 0.92

15 18 2.5 1.5e+02 2.7 0.6 2 23 1101 1122 1101 1122 0.95

16 18 0.73 43 4.4 0.5 2 23 1224 1245 1224 1245 0.94

17 18 0.054 3.2 8.0 0.0 1 23 1255 1277 1255 1277 0.96

18 18 0.00021 0.013 15.5 1.0 1 23 1284 1306 1284 1306 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	1.2e-05	0.00073	19.4	3.1	1	23	312	334	312	334	0.98
2	18	0.34	20	5.4	6.2	1	23	340	362	340	362	0.97
3	18	1.7e-07	9.9e-06	25.3	3.2	1	23	368	390	368	390	0.99
4	18	1.2e-05	0.00073	19.4	0.4	1	23	396	418	396	418	0.99
5	18	0.012	0.71	10.0	0.2	2	23	491	515	490	515	0.92
6	18	0.0038	0.22	11.6	0.2	2	23	543	565	542	565	0.95
7	18	0.061	3.6	7.8	0.7	1	23	648	670	648	670	0.97
8	18	0.003	0.18	11.9	0.1	2	23	678	699	677	699	0.91
9	18	0.0025	0.15	12.2	0.1	1	23	707	731	707	731	0.90
10	18	3.5	2.1e+02	2.3	0.1	2	20	737	755	736	756	0.92
11	18	1.3	76	3.6	0.9	2	23	767	789	766	789	0.95
12	18	0.0025	0.15	12.2	1.1	1	23	842	865	842	865	0.97
13	18	0.0049	0.29	11.2	1.2	2	23	1043	1065	1042	1065	0.96
14	18	0.11	6.7	7.0	0.1	1	23	1071	1093	1071	1093	0.92
15	18	2.5	1.5e+02	2.7	0.6	2	23	1101	1122	1101	1122	0.95
16	18	0.73	43	4.4	0.5	2	23	1224	1245	1224	1245	0.94
17	18	0.054	3.2	8.0	0.0	1	23	1255	1277	1255	1277	0.96
18	18	0.00021	0.013	15.5	1.0	1	23	1284	1306	1284	1306	0.97

Sequence Information

Coding Sequence: ATGTCCCGACGCAAACAGGCCAAGCCGCGCGCCTGTCTCAAACTTGGcgaaaaggaggaggagcaggagcaaaagcCCAATGCGGATGACCTGCTGGAGccgaaggaggagctgctcagTGCCGAcgaggatggggatggggatggggatggggatgtggaCTCCGATGAAGAGGAGGATGCTGAGGGAGAGCTGCTTACTGAGGAGAGGCCACTCAAGCCCAATGAATCACAGCCACAAAGCCACTGGACAACAGCTGATGAGGATCCAGGCAGGGCCTCGGCTGTgccaaaagaagaagcagaagaactACAACACCCACGGGATAAGGAAGgtcctgctgtggctgctgctgctggtgcatcCGATGCAGCTGCCAATGCCAACGGGCACTGCAAGTCCTCTGGTAAcagtgaaAGCGCAGTGgaggaggaggagccagaAGACATGGACTTGGATGACGACCTGCTGAGTCTCAGTGGCGAGGAGGACTACGATGATGAAGAGCTGCAAAGTCTGGACAGCTTTTACTCAGACATGTACAGTACCCACACCTCGTCCAGCTACTCGCCGAGCATATCCGACGGCACGATGACACCCAATGCCCATCATCTGGCGGCTGCCTCAGGGAATGCTTTACAGGAGGATCTCCACCACACGGCTGATGGCAAGTCCAACGGTGTGCCCGGCGCGGAGGAGCCTGCCAAGCCTGCGAAGCGACAGCCGCACttccaccatcaccatcatcactACCATCACCAGCAGGCCCTGAAGATTGCCAACAAGCTGCGCAAAATCAATAAGGAGGCCAAGCTGGCAGCCGCCGGAGGAGCAggcgctggagctggtgccGGGGCCggagctggcgctggtgcAGCCGCAAAGTTTGATAAGTTGACAGGCGAAGGCATTAAGAGTCGCGGCGACGGCTCCTATCAGTGCCAGTTCTGTGATAAGACATTTCCCCGTCTCGGCTACTTGAAGCATCACGTGCAGAGCCATGCCGAGCACTTGCCCTTCAAGTGCGAGTACTGCGCCAAGCTGTTCAAGCACAAGCGCTCCCGGGATCGCCACAAGAAGCTGCACACCAACGAGCGGAACTACAAGTGTCCACACTGCGAGGCAGCCTTCTCCAGGAGCGATCATCTGAAGATCCACATGAAGACGCACGACATACAGAAACCGTTCCAGTGCAGCATGTGCAACCGGGGCTACAACACGGCTGCCGCACTCACCTCGCACATGCAGAAGCACAAGAAGAATGCCGCCATACTGGCAGCCGGCGGCAATCCCAATGCCCTCAACTATAGTCCCAGGTCCACGGGCTCCGCCTCGGCGTCCGTGTCCAGCAATGGGAGTCTGCACAAGCGGCGCTAtgcgctggctctggccacCGACAGCAGTCCCAGTCGGTTGGACTTTCCCAAGAGATCGCGCAGCAGTCAtgtgcccacgcccacgccgctgctgcgctgcagctACTGCCCCAAGGTGACGGAGTTCAGCAGCCTCGAGCAGCTGAATGCACATCTCCAGAGTGtccacgagcagcagcagcagtcccagcagGAGCGACAGCCATCGGGCAAGAGCAATGCCGTGCAGGAGGCGGACACCTTCCAGCTGAGCTGCGAATATTGCACCATGAAGTTCGGCAACATTGCCGGCCTCTTCCAGCACATGCGCGCCACCCACTTGGATCGTCTGAGCAGCCCCAACTCCTACTACGAGCACTTCAATCGCCTGGCCACCGCGGGCACCTTCAGTCCGCGACTGGCGCTGGATTTGCCCAAGATTAAGCCGGATCTGGGCAGCCCGGAGCGAGAGAACCGAGCCTCGGAGGAGGACCTGCCCACGGATCTGAGCAGCAACAAGCGAAGACCACCGACGCCAGCCAAcaatcctcctcctccaccgcaGGCAGCGGCCCCTCCCGGCATCTTCTTCTGCAATCAGTGCAACGCGGGACTGCCCGACTTTGAGAGTTTCCGCAATCATCTGAAGAGTCACATTGCCGAGGGCATGCAGCTGGTCTGTCCCCACTGCGGGCTGAGTCTGCCGGAGCAGTCGGACTTCGAGCGGCACGTCGTGGGGCACTTCCTCATCGCCAGCTCCGAGTTCAACTGCGGCTCCAGCTGTGGCAAGAGCTTCGGCAAggcggaggagctgcagcagcatctcagCGCCGAGCATGTCCTCACGCTGCTGAAGTGCGCCCTCTGCTCGGAGGTGTGCGACACGCGCATGGCCATGCAGCTCCATCTGGCCTGCGCCCACAGCCAGGAGACGAagctgctgcgctgcagcGCCTGCATGGAGGTCTTCCGCTCCGACGGGGACTTCCATGTGCACGTCAAGACGCGCCACCAGCTGGTCGGCGGcaaccatcatcagcagcagcagcagcagcagcacccacaccAGCATCATCCCGCATCCAATCCGCTGCAGTGCATGTTCTGCCGTGCCGTTTGCTCCTCCGAGCTGGAGATGCACTTCCATCTGGCGGCGCATGCGCGACAGTTCCGCTGCCCCTCCTGCCCGGAGACCTTCCACGTGGAGTTTCTGCTGGACAGGCACATGCAGAGCCAGCATGGCGGCGCCAAGGACAAGgagcagagCTCGCCCAACATGGGCAGCCTCTATGTGAAcgcgctgctgccaccgctcgcagcagctgccgcagccgcagcggccaccaacaacaacagcagcatcatcgaCTACAACGTGGCCTTCAAGGGGTTGTTCGGCGGGGGAGGATCTGCCAGCGGAGCCAGTGCACCCACTGGGTCCAAGTTCTACAGCCCGCTGCAGGTGGACACGAAGGCGCAAAGCTCGCCACATCCCGCGCTGATGTACGGCCTCAGCCAGCGCTATCTGATGGAGATGTACGCCGCCAAGTCCACGTCGCCGGTGAACAGCAGCGCCCACGaatcagcaggaggaggaggaggaggaccaggagctgctgccgctccaccagcaccacaagCGCCTCCGCCGCAAGCCACTCCAGCTGCCACCTTCAGCTGCGGCATGTGCGAGCGGCAGGATCTGCGCAGCGAGGCGGAACTCCACTCGCACCGGAAGCTGGCCCACAACCTCAAGACGGGCGTCAGCCTGCGCTGCGCCTACTGCGCGGGCAACTTCAAGTCGCGggcggagctggagcagcacatGAAGAGCTGCCACAACTCGACGGGCAAACACAAGTGCCTCATCTGCGACGAGATCTTCCCCTCGCCGGCCATCCTCGCGGAGCACAAGCTGCAGCACTCGAAGGTGGGGCAGTCGGGCAAGTGCGCCCACTGCAGCCATCCGCTGGAGGATGTCGCCGCCTTCCGGGCCCACCTCAGCGAACATGGCAGCGACGGGGCCTCCCTGCCGCTGGCCTGCATCTGCTGTCGCCAGACCCTGCACTCGGAGTTCGAGCTGAGTCTCCATGCCAAGTTCCACACGAAGTCCGCGtccagcggcggcagcctgCAGGAGCCAGCCTGCGCCCTCTGCCTGGAGCCACTGCCCGGGCCAGTGGAGGGGCCCACCACTCCAGCGAAGCTCTGCGAGAAGTGCTGCCGCAAGCACAACCTCAACGGCAAGCGGAGCAAGGGCAGCGAGGCGCCCGTGCTCCAGGCCCCGCCACCGGCGGCGCCCTACCTGGAGAACCGCTGCAACCTGTGCAAGATGATCCTGCCACACGCCcagaagctgcaggagcacCTCGTGGAGCACACCTTTGCGGGCACCGAGCAGCGCGGCTACAACTGCTACATCTGCTCGGCTGTGTTCACGGCACCCGGCGGCCTCCTCGGCCACATGGCGGAGCACGGCGCCCACTCGCGGCCCTACGACTGCAGCATTTGCCCCGAGAAGTTCTTCTTCCGCGCCGAGCTGGAGCACCACCAGCGGGCACACGAGCTGCGTCCAGCGGTGCATCGTCCAGCGATGGCCAAGCCAGAGCCTCCGCTGCGACGCAGCGCCTCGCCCAGTCCGAGTCCCGTGCGAAGTCCCACGACCGTCAAGCAGGAGCTCTACGACTCGGATACGGCGCACTCGGGTGCCGATGAGCCAGAGCCCGctgcggaggaggaggagtacatAGAGGTGGAGCAGGTGCCACACGAGACGCGGCCCAGGGATGTCATGTCCCAGCTGGAAAGGGCCACAAACAGCGCCTGA
Protein Sequence: MSRRKQAKPRACLKLGEKEEEQEQKPNADDLLEPKEELLSADEDGDGDGDGDVDSDEEEDAEGELLTEERPLKPNESQPQSHWTTADEDPGRASAVPKEEAEELQHPRDKEGPAVAAAAGASDAAANANGHCKSSGNSESAVEEEEPEDMDLDDDLLSLSGEEDYDDEELQSLDSFYSDMYSTHTSSSYSPSISDGTMTPNAHHLAAASGNALQEDLHHTADGKSNGVPGAEEPAKPAKRQPHFHHHHHHYHHQQALKIANKLRKINKEAKLAAAGGAGAGAGAGAGAGAGAAAKFDKLTGEGIKSRGDGSYQCQFCDKTFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASASVSSNGSLHKRRYALALATDSSPSRLDFPKRSRSSHVPTPTPLLRCSYCPKVTEFSSLEQLNAHLQSVHEQQQQSQQERQPSGKSNAVQEADTFQLSCEYCTMKFGNIAGLFQHMRATHLDRLSSPNSYYEHFNRLATAGTFSPRLALDLPKIKPDLGSPERENRASEEDLPTDLSSNKRRPPTPANNPPPPPQAAAPPGIFFCNQCNAGLPDFESFRNHLKSHIAEGMQLVCPHCGLSLPEQSDFERHVVGHFLIASSEFNCGSSCGKSFGKAEELQQHLSAEHVLTLLKCALCSEVCDTRMAMQLHLACAHSQETKLLRCSACMEVFRSDGDFHVHVKTRHQLVGGNHHQQQQQQQHPHQHHPASNPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGAKDKEQSSPNMGSLYVNALLPPLAAAAAAAAATNNNSSIIDYNVAFKGLFGGGGSASGASAPTGSKFYSPLQVDTKAQSSPHPALMYGLSQRYLMEMYAAKSTSPVNSSAHESAGGGGGGPGAAAAPPAPQAPPPQATPAATFSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCAGNFKSRAELEQHMKSCHNSTGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCSHPLEDVAAFRAHLSEHGSDGASLPLACICCRQTLHSEFELSLHAKFHTKSASSGGSLQEPACALCLEPLPGPVEGPTTPAKLCEKCCRKHNLNGKRSKGSEAPVLQAPPPAAPYLENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGYNCYICSAVFTAPGGLLGHMAEHGAHSRPYDCSICPEKFFFRAELEHHQRAHELRPAVHRPAMAKPEPPLRRSASPSPSPVRSPTTVKQELYDSDTAHSGADEPEPAAEEEEYIEVEQVPHETRPRDVMSQLERATNSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00548267;
90% Identity: -
80% Identity: -