Basic Information

Insect: Drosophila merina
Gene Symbol: L
Assembly: GCA_035047645.1
Location: JAWNPH010000089.1:3138492-3144490[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 3.1e-05 0.0029 18.2 2.9 1 23 154 176 154 176 0.98

2 17 0.14 13 6.7 7.3 1 23 182 204 182 204 0.97

3 17 1.5e-07 1.4e-05 25.5 3.2 1 23 210 232 210 232 0.99

4 17 1.1e-05 0.001 19.6 0.4 1 23 238 260 238 260 0.99

5 17 0.011 0.99 10.2 0.2 2 23 343 367 342 367 0.92

6 17 0.0013 0.12 13.0 0.4 2 23 389 411 388 411 0.96

7 17 0.055 5 8.0 0.7 1 23 490 512 490 512 0.97

8 17 0.0049 0.44 11.3 0.1 3 23 521 541 519 541 0.92

9 17 3.8e-05 0.0034 17.9 0.3 1 23 549 573 549 573 0.96

10 17 4.5 4.1e+02 2.0 0.9 2 23 609 631 608 631 0.94

11 17 0.0023 0.21 12.3 1.1 1 23 676 699 676 699 0.97

12 17 0.0044 0.41 11.4 1.2 2 23 892 914 891 914 0.96

13 17 0.036 3.3 8.6 0.1 1 23 920 942 920 942 0.92

14 17 0.043 3.9 8.3 0.1 2 23 950 971 949 971 0.96

15 17 0.66 60 4.6 0.5 2 23 1075 1096 1075 1096 0.94

16 17 0.0067 0.61 10.9 0.0 1 23 1106 1128 1106 1128 0.96

17 17 0.00021 0.019 15.6 1.2 1 23 1135 1157 1135 1157 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	3.1e-05	0.0029	18.2	2.9	1	23	154	176	154	176	0.98
2	17	0.14	13	6.7	7.3	1	23	182	204	182	204	0.97
3	17	1.5e-07	1.4e-05	25.5	3.2	1	23	210	232	210	232	0.99
4	17	1.1e-05	0.001	19.6	0.4	1	23	238	260	238	260	0.99
5	17	0.011	0.99	10.2	0.2	2	23	343	367	342	367	0.92
6	17	0.0013	0.12	13.0	0.4	2	23	389	411	388	411	0.96
7	17	0.055	5	8.0	0.7	1	23	490	512	490	512	0.97
8	17	0.0049	0.44	11.3	0.1	3	23	521	541	519	541	0.92
9	17	3.8e-05	0.0034	17.9	0.3	1	23	549	573	549	573	0.96
10	17	4.5	4.1e+02	2.0	0.9	2	23	609	631	608	631	0.94
11	17	0.0023	0.21	12.3	1.1	1	23	676	699	676	699	0.97
12	17	0.0044	0.41	11.4	1.2	2	23	892	914	891	914	0.96
13	17	0.036	3.3	8.6	0.1	1	23	920	942	920	942	0.92
14	17	0.043	3.9	8.3	0.1	2	23	950	971	949	971	0.96
15	17	0.66	60	4.6	0.5	2	23	1075	1096	1075	1096	0.94
16	17	0.0067	0.61	10.9	0.0	1	23	1106	1128	1106	1128	0.96
17	17	0.00021	0.019	15.6	1.2	1	23	1135	1157	1135	1157	0.97

Sequence Information

Coding Sequence: ATGATGGCCCTAAAGATGTTATATCGCGGTCCCAGTTCGCGTTTGGAGAACTTAATCGAAAAGATCCAGGCCACCAAGGAGATAACCAATAACgATATTTATAGTACTCACACATCGTCCAGTTACTCACCAAGCATTTCGGACGGCACCATGACACCCAATTCACACCATTTGCCAGGAGCTCCTGCACCCCTGCCCGGCCAGGATCCGGATCATCCCGGCGAGGGCAACACCAATGGCGGCCTCGACGGCGAAGAGCTGATCAAGCCGAAGCGCCTGCCCCATTTCCATCATCATCACCATCACTACCATCACCAGCAGGCGCTGAAAATCGCCAACAAGCTGAGGAAAATCAATAAGGAAGCCAAGCTGGGAGCCCTCGGTGCTGGCTCCGGAGGAGCTGGCTCCAAGTTTGATAAGTTGACAGGCGAGGGGATTAAAAGTCGCGGCGACGGCTCCTATCAGTGTCAGTTCTGCGAGAAGTCATTTCCGCGTCTCGGTTACTTAAAGCATCACGTGCAGAGCCACGCCGAACACCTGCCTTTCAAGTGCGAGTACTGCTCCAAGCTTTTCAAGCACAAGCGCTCCCGCGATCGCCACAAGAAGTTGCACACCAACGAGAGGAACTACAAGTGTCCCCATTGCGAGGCGGCATTTTCCAGGAGTGACCATCTTAAAATCCACATGAAAACCCACGACATCCAGAAGCCCTTCCAGTGCAGCATGTGCAACAGAGGGTACAACACGGCGGCCGCTTTGACTTCCCACATGCAGAAGCACAAGAAGAATGCAGCCATCCTGGCCGCTGGTGGCAATCCCAATGCCCTCAACTATAGTCCTCGGTCCACCGGATCGGCCTCGGCTTCGGTTTCCAGCAACGGGAGCCTGCACAAGCGACGCTACGCCCTGGCTCTGGCCACGGACAGCAGTCCCAGTCGCTTGGATTACCCCCAGAAGAGGTCGAGGGGTGgaaccaccagcaccaccgcTGCTGCCACAGCCAatgccacgcccacgcccCTGCTAAGGTGCAGCTACTGTCCCAAGGTGACGGAGTTTAGCAGCCTGGAGCAGCTGAATGCCCACTTGCAAAGTGTCCACGAGCAGCCCCAGCCGCCGATGAAGACTCCCGGCCACTCGCAGGAGTCGGATGGCTTCCAGTTGAGCTGCGAATACTGCACCATGAAGTTTGGCAACATAGCCGGACTCTTCCAGCACATGCGGAGCACTCACCTGGACAGGCTGAGCAGCCCGAACTCCTACTACGAGCACTTCAATCGCCTGGCCACCGCCGGAACCTTCAGTCCCCGCCTGGCCTTGGATCTGCCCAAGATCAAGCCGGATTTGAGTAGCCCCGACCAGCGGGAGCTGCGTCCCGCGGAAGAGGATCTGCCCACGGACTTGAGCAGCAACAAGAGACGACCCCTGACCCCGAACCCTCAGCCTCCACCAGCCCCGCCGGGCGTCTTCTTCTGCAACCAATGCAACGCCGGCTTGCCCGACTTCGAGAGCTTCAGGAATCACCTGAAGAGCCACATTGCCGAGGGAATGCAGCAGATTTGCCCGCATTGTGGCCTGAGCCTGCCGGAGCAGTCGGACTTCGAGCGCCACGTGGTGGGTCACTTCCTGATCACCGGATCCGAGTTCAACTGCAACTCCAGCTGTGGCAAGAGTTTCGCCAAGGCGGAGGACCTGCAACAGCACCTCCTCACCGAGCACGTCCTCACTCTCCTGAAGTGTTCCCTGTGCTCGGAGCTCTGCGAGAGCCGGATGGCCATGCAGCTTCACCTGGCCTGTTCCCACAGCCAGGAGACCAAGTTGCTCCGCTGCAGCGCCTGCCTGGAGCTCTTCCGCTCGGACGCCGAGTTCCATGTGCATGTGAAGACGCGTCACCAGCTGGGCGGACATCCGGCTTTGGGCGCCACTTCGAACGCTCCCTCCAACCCTCTGCAGTGCATGTTTTGCCGAGTTGTTTGCTCCTCGGAACTGGAGATGCACTTCCACTTGGCCGCCCATGCCCGGCAGTTCCGGTGTCCCTCTTGCCCCGAGACCTTCCACGTGGAGTTCCTCCTGGATCGTCACATGCAGAGCCAGCAtggaggaggagctggaggcGGAGGAGCTGGCGGGAAGGACAAAGAGGCCAGTTCGCCCAACATGGGCAGCCTGTATGTGAACGCCCTCTTGCCACCTttggcggcagcagcagctgcggcAGCAGCCactaacaacaacagcagcatcaTCGATTACAATGTGGCATTCAAGGGCTTGTTCGGAGGATCAGCGGCAGGTGGAGCCGGTTCAGGAGCACCCTCTGGACAAACCTCGAAGTTCTACAGCCCGCTGCAAGTGGACACCAATGCCCTGAAGGCACAAACCTCTCCCCATCCGGCCTTGATGTACGGCCTAAGCCAGAGGTACTTGATGGAAATGTATGCCGCCAAATCGGCATCGCCACCGGGAAATGAGGGTGGATCCAATGGCCAGTCAGTCGGAGCCCAGGCAGCCGCTGTAgcaccaccgccaccaccagCACCGGCCCCACCACAGGCGCCAGTGCCACCCACCACGTTCAGTTGCGGCATGTGCGAGCGTCAGGATTTAAGGAGCGAGGCGGAGCTCCATTCACATCGGAAGCTGGCCCACAACCTCAAGACCGGAGTAAGTCTCAGATGCGCCTACTGTGCCGGCAACTTCAAGTCCCGGGCAGAGCTGGAGCAGCACATGAAGAGCTGCCACAACTCGACGGGCAAGCACAAGTGCTTGATTTGCGACGAGGTCTTTCCCTCGCCGGCCATCCTGGCGGAGCACAAGTTGCAGCACTCCAAGGTGGGGCAGTCGGGCAAATGTTCGCACTGCGGCCAGCCTCTGGAGGATGTGGCCGCCTTCAGGGCCCATCTCTCCGAGCACGGCAGTGACGGGGCCTCCCTGCCCCTGGCCTGCATCTGCTGTCGCCAGACCCTGCACTCGGAGTTCGAGTTGAGTCTGCACGCCAAGTTCCACACCAAGTCCGCGTCCAGTGGTGGCAGCCTCCAGGAGCCAGTGTGTGCCCTGTGCCTAGAGCCCCTGCCAGACGCCACGGAGGGTCCTGCCAAGCTGTGCGAGAAGTGCTGCCGGAAGCACAATCTGAATGGCAAGAGGAGCAAGCCTCCAAGTGAACCACCGTCTCAGAATCTGCAGCCAATCCAGCCCCCATCCGGCGCAGCCTTCGTGGAGAACCGCTGCAACCTCTGCAAGATGATCCTGCCACATGCCCAGAAGCTGCAGGAGCACCTGGTGGAGCATACCTTTGCCGGAACCGAGCAGCGAGGCTACAACTGTTACATCTGCTCGGCGGTTTTCACGGCACCCGGTGGCCTGCTCAACCACATGGCCGAGCATGGCGCCCACACGCGTCCCTATGACTGCAACCTCTGCCCGGAGAAGTTCTACTTCCGGGCGGAACTGGAGCACCACCAGCGGGGCCATGAGCTGAGGCCCCAGGCACGGCCCAAGCTGGAAGTGCCGTCCAACAGGACCAACTCGCCCATCGACAGTCCCGTGCGAAGTCCCACGATTGTGAAGCAGGAAATGTACGAAACGGATACGGCCCAGTCGACCGGAGGAGACGACGAGGAACCGGAAAACACCCACGAGGACGAGGAGTACATCGAGGTGGATATGCCCCACGAGGCGCGTTCCAGCGACTTGGGCTCGCAAATGGAGAGGCCCACCAGTAGCGCCTAG
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEITNNDIYSTHTSSSYSPSISDGTMTPNSHHLPGAPAPLPGQDPDHPGEGNTNGGLDGEELIKPKRLPHFHHHHHHYHHQQALKIANKLRKINKEAKLGALGAGSGGAGSKFDKLTGEGIKSRGDGSYQCQFCEKSFPRLGYLKHHVQSHAEHLPFKCEYCSKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASASVSSNGSLHKRRYALALATDSSPSRLDYPQKRSRGGTTSTTAAATANATPTPLLRCSYCPKVTEFSSLEQLNAHLQSVHEQPQPPMKTPGHSQESDGFQLSCEYCTMKFGNIAGLFQHMRSTHLDRLSSPNSYYEHFNRLATAGTFSPRLALDLPKIKPDLSSPDQRELRPAEEDLPTDLSSNKRRPLTPNPQPPPAPPGVFFCNQCNAGLPDFESFRNHLKSHIAEGMQQICPHCGLSLPEQSDFERHVVGHFLITGSEFNCNSSCGKSFAKAEDLQQHLLTEHVLTLLKCSLCSELCESRMAMQLHLACSHSQETKLLRCSACLELFRSDAEFHVHVKTRHQLGGHPALGATSNAPSNPLQCMFCRVVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGGAGGGGAGGKDKEASSPNMGSLYVNALLPPLAAAAAAAAATNNNSSIIDYNVAFKGLFGGSAAGGAGSGAPSGQTSKFYSPLQVDTNALKAQTSPHPALMYGLSQRYLMEMYAAKSASPPGNEGGSNGQSVGAQAAAVAPPPPPAPAPPQAPVPPTTFSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCAGNFKSRAELEQHMKSCHNSTGKHKCLICDEVFPSPAILAEHKLQHSKVGQSGKCSHCGQPLEDVAAFRAHLSEHGSDGASLPLACICCRQTLHSEFELSLHAKFHTKSASSGGSLQEPVCALCLEPLPDATEGPAKLCEKCCRKHNLNGKRSKPPSEPPSQNLQPIQPPSGAAFVENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGYNCYICSAVFTAPGGLLNHMAEHGAHTRPYDCNLCPEKFYFRAELEHHQRGHELRPQARPKLEVPSNRTNSPIDSPVRSPTIVKQEMYETDTAQSTGGDDEEPENTHEDEEYIEVDMPHEARSSDLGSQMERPTSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00548267;
90% Identity: iTF_00615690;
80% Identity: -