Basic Information

Insect: Drosophila burlai
Gene Symbol: L_1
Assembly: GCA_008042655.1
Location: VNJT01006236.1:102800-110103[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 1e-05 0.00077 19.8 2.9 1 23 159 181 159 181 0.98

2 17 0.15 12 6.7 7.3 1 23 187 209 187 209 0.97

3 17 1.7e-07 1.3e-05 25.5 3.2 1 23 215 237 215 237 0.99

4 17 1.2e-05 0.00095 19.6 0.4 1 23 243 265 243 265 0.99

5 17 0.012 0.92 10.2 0.2 2 23 350 374 349 374 0.92

6 17 0.0015 0.11 13.0 0.4 2 23 396 418 395 418 0.96

7 17 0.061 4.7 7.9 0.7 1 23 506 528 506 528 0.97

8 17 0.0042 0.32 11.6 0.1 2 23 536 557 535 557 0.92

9 17 9.3e-05 0.0071 16.8 0.4 1 23 565 589 565 589 0.94

10 17 4.9 3.8e+02 1.9 0.9 2 23 625 647 624 647 0.94

11 17 0.0025 0.19 12.3 1.1 1 23 693 716 693 716 0.97

12 17 0.0049 0.38 11.4 1.2 2 23 908 930 907 930 0.96

13 17 0.04 3.1 8.5 0.1 1 23 936 958 936 958 0.92

14 17 0.048 3.7 8.3 0.1 2 23 966 987 965 987 0.96

15 17 0.73 56 4.6 0.5 2 23 1092 1113 1092 1113 0.94

16 17 0.0096 0.73 10.5 0.0 1 23 1123 1145 1123 1145 0.96

17 17 0.00017 0.013 16.0 1.7 1 23 1152 1174 1152 1174 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	1e-05	0.00077	19.8	2.9	1	23	159	181	159	181	0.98
2	17	0.15	12	6.7	7.3	1	23	187	209	187	209	0.97
3	17	1.7e-07	1.3e-05	25.5	3.2	1	23	215	237	215	237	0.99
4	17	1.2e-05	0.00095	19.6	0.4	1	23	243	265	243	265	0.99
5	17	0.012	0.92	10.2	0.2	2	23	350	374	349	374	0.92
6	17	0.0015	0.11	13.0	0.4	2	23	396	418	395	418	0.96
7	17	0.061	4.7	7.9	0.7	1	23	506	528	506	528	0.97
8	17	0.0042	0.32	11.6	0.1	2	23	536	557	535	557	0.92
9	17	9.3e-05	0.0071	16.8	0.4	1	23	565	589	565	589	0.94
10	17	4.9	3.8e+02	1.9	0.9	2	23	625	647	624	647	0.94
11	17	0.0025	0.19	12.3	1.1	1	23	693	716	693	716	0.97
12	17	0.0049	0.38	11.4	1.2	2	23	908	930	907	930	0.96
13	17	0.04	3.1	8.5	0.1	1	23	936	958	936	958	0.92
14	17	0.048	3.7	8.3	0.1	2	23	966	987	965	987	0.96
15	17	0.73	56	4.6	0.5	2	23	1092	1113	1092	1113	0.94
16	17	0.0096	0.73	10.5	0.0	1	23	1123	1145	1123	1145	0.96
17	17	0.00017	0.013	16.0	1.7	1	23	1152	1174	1152	1174	0.98

Sequence Information

Coding Sequence: ATGATGGCCCTAAAGATGTTATATCGCGGTCCCAGTTCGCGTTTggagaatttaattgaaaagatCCAGGCCACCAAGGAGATAACCAATAGcgACATGTACAGTACCCACACATCGTCCAGCTACTCGCCTAGCATTTCGGATGGCACCATGACGCCCAATTCCCACCATTTGCCCGGAGCTCCAACCTCTGTGCTAGCCTCTGGCCAGGAGGATCATCATCAATCGGCTGATGGCAAGCTCAATGGTGGCCCCGATGGCGAGGAGCTGGCCAAACCGAAGCGCTTGCCACACttccatcaccatcaccatcatcactACCACCATCAGCAGGCGCTGAAAATCGCCAACAAGCTGCGCAAAATCAATAAGGAAGCCAAAATGGGAGCTGGCGGCGGTGCTGGTGCCGGAGGAGCAGGCTCCAAGTTTGATAAGTTGACAGGCGAGGGGATTAAGGCCCGCGGCGACGGCTCCTATCAGTGTCAGTTCTGCGATAAGTCATTTCCGCGTCTCGGCTACTTGAAGCATCACGTACAGAGCCACGCCGAACACCTGCCCTTCAAGTGCGAATACTGCTCGAAGCTGTTCAAGCACAAGCGATCCCGGGATCGCCACAAGAAGCTGCACACCAACGAGCGCAACTACAAGTGTCCCCATTGCGAGGCGGCCTTCTCCAGGAGTGACCACCTGAAGATCCACATGAAGACGCACGACATTCAGAAACCGTTCCAGTGCAGCATGTGCAACCGGGGCTACAACACGGCGGCCGCCCTGACCTCACACATGCAGAAGCACAAGAAGAATGCGGCCATCCTGGCCGCTGGGGGAAATCCCAATGCCCTGAACTACAGTCCCCGATCCACGGGATCGGCCTCGGCCTCGGTCTCCAGCAATGGCAGTCTGCAGAAGAGGCGATATGCCTTGGCTCTGGCCTCCGATAGTAGTCCCAGCCGGTTGGACTTTCCCAAGCGATCCAGAAGCAGTCACCAGCCACATGGTAATGGAGGCGGCACCACCAACACCACGGCCACACCCACGCCCCTGCTGAGGTGCAGCTACTGCCCCAAGGTCACGGAGTTTAGCAGCTTGGAGCAGCTGAATGCCCACCTGCAAAGTGTCCacgagcagcagccgcagcttGCGACCAAGACGCCGGTGGCTCCGGAGAGCGAGGGCTTCCAGCTGAGCTGCGAGTATTGCACCATGAAGTTCGGCAATATTGCCGGCCTCTTCCAGCACATGAGGAGCACTCACCTGGACAGATTAAGCAGCCCGAACTCCTACTACGAGCACTTCAATCGCCTGGCCACCGCCGGAACCTTCAGTCCGCGTCTGGCCCTGGAGCTGCCTAAAATCAAGCCGGATTTGGGCAGCCCGGAGAGGGAGAACACGCGAGCTGCGGAGGAGGATCTGCCCACCGATTTGAGCAGCAACAAGCGGCGACCCCAGACACCCACGAatgcccagcagctgcagtcCCAGCAGCTGGCACCACCAGCCGCCCCGCCTGGAGTGTTCTTCTGCAATCAGTGCAACGCCGGGCTGCCGGACTTCGAGAGCTTCAGGAATCACCTGAAAAGCCACATCGCCGAGGGCATGCAGATGGTGTGTCCCCACTGCGGCCTGAGCCTGCCGGAGCAGTCGGAGTTCGAGCGCCATGTGGTGGGCCACTTCCTCATCACCGGCTCCGAGTTCAactgcagctccagctgcgGCAAGAGCTTCGCCAAGTCGGAGGACCTGCAGCAGCACCTGCTCTCCGAGCACGTGCTCACCCTGCTGAAATGCTCCCTGTGCTCGGAGCTCTGCGAGAGCCGGATGGCCATGCAGCTGCACCTGGCCTGCGCCCACAGCCAGGAGACGAAGCTGCTGCGCTGCAGCGCCTGCCTGGAGCTCTTCCGCTCCGATGCCGAGTTCCATGTGCATGTGAAGACGCGCCACCAGCTGGGCGGCGGTCATCCCGCGCTGGGCGCCACCCCGAGTGCCCCTGCCAATCCACTGCAGTGCATGTTCTGCCGGGCTGTCTGCTCCTCGGAGCTGGAGATGCACTTTCATCTGGCGGCGCACGCCAGGCAGTTCCGGTGCCCCTCCTGCCCGGAGACCTTCCACGTGGAGTTCCTGCTGGACAGGCACATGCAGAGCCagcacggcggcggcggtggggccaaggacaaggagcagcagcggggcTCGCCCAACATGGGCAGTCTCTATGTGAATGCCTTGCTGCCTCCcctggcggcagcggcggcggcagcagcggccaccaacaacaacagcagcatcatcgACTACAATGTGGCATTCAAGGGTCTCTTTGGAggcggagcaggagcgggCGCAGCCTCTGGACCAGGTTCGGGCTCGGGAGGAGGATCCGGAGCAGCCCCGCCCTCGGGCAACAAGTTCTACAGTCCCCTGCAGGTGGACACCAATGCCTTGAAGGCTCAGACCTCCCCGCACCCCGCCCTCATGTACGGCCTGAGCCAGCGCTATCTGATGGAGATGTACGCCGCCAAGTCCACTTCACCGGCGGGCGGCGCCAACGAGGGCAATCCACAGCCACCACAGGCGACGGCTCCGCCGAGTGCGCCACCGAGTGCCGCTCCAGCCGCTGCCACCTTCAGCTGTGGCATGTGCGAGCGCCAGGATCTACGCAGCGAGGCGGAGCTGCACTCGCACCGCAAGCTGGCCCACAACCTCAAGACAGGCGTGAGCCTCAGGTGTGCCTACTGTGCCGGGAACTTCAAGTCGCGggcggagctggagcagcacaTGAAGAGCTGCCACAATTCGACGGGCAAGCACAAGTGCCTGATCTGCGACGAGGTCTTCCCCTCGCCGGCCATACTGGCCGAGCACAAGCTGCAGCACTCGAAGGTGGGCCAGTCGGGCAAGTGCTCCCACTGTGGCCAGCCGCTGGAGGATGTGGCCGCCTTCAGAGCCCACCTCTCGGAGCACGGCAGCGACGGGGCCACCCTGCCGCTGGCCTGCATCTGCTGTCGCCAGACCCTGCACTCGGAGTTCGAGCTGAGCCTGCACGCCAAGTTCCACACGAAGTCGGCCTCGAGTGGGGGCAGCCTCCAGGAGCCGGTGTGTGCTCTGTGCTTGGAGCCGCTGCCCGATGTTCCGGTCGAGGGCCCGGCCAAACTGTGCGAGAAGTGCTGCCGGAAGCACAACCTCAATGGGAAGCGGGGAAAGCCAagtgagcagcagctgcaggcacctccaccctcAGCAGGAGCCGGATCAGGAGCTTCCTTTGTGGAGAACCGCTGTAATTTGTGCAAGATGATCCTGCCGCATGCCCAGAAGCTGCAGGAACACCTGGTGGAGCACACCTTTGCGGGCACCGAGCAGCGCGGCTTCAATTGCTACATCTGCTCGGCGGTATTCACGGCCCCGGGAGGCCTCCTCAATCACATGGCAGAGCATGGAGCGCACTCGCGTCCCTACGACTGCAGCCTGTGCCCGGAGAAGTTCTACTTCCGGGCTGAGCTGGAGCACCATCAGAGGAGCCACGAGCTGAGGCCACAGGCCACGAGGCCGCCAATGCCCAAGGTGGAGACTCCCTCCATCAGGAACAGTTCACCCATCTGCGAGAGTCCTCCCTCCAGGAGTCGCAGTCCCACGATCAATGTCAAGCAGGAACTCTACGAAACGGACACTGTGGAGTCGGGAGCCGGAGAAGATGAGCCCGAGGAGAATCCCCAGGAAGATGAGGAGTACATTGAAGTGGAGCAGGTGCCGCATGAGACGCGTCCCAGTGAGATGGGTTCACAGCTGGAAAGGTCCACCAGTAGCGCCTAA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEITNSDMYSTHTSSSYSPSISDGTMTPNSHHLPGAPTSVLASGQEDHHQSADGKLNGGPDGEELAKPKRLPHFHHHHHHHYHHQQALKIANKLRKINKEAKMGAGGGAGAGGAGSKFDKLTGEGIKARGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCSKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASASVSSNGSLQKRRYALALASDSSPSRLDFPKRSRSSHQPHGNGGGTTNTTATPTPLLRCSYCPKVTEFSSLEQLNAHLQSVHEQQPQLATKTPVAPESEGFQLSCEYCTMKFGNIAGLFQHMRSTHLDRLSSPNSYYEHFNRLATAGTFSPRLALELPKIKPDLGSPERENTRAAEEDLPTDLSSNKRRPQTPTNAQQLQSQQLAPPAAPPGVFFCNQCNAGLPDFESFRNHLKSHIAEGMQMVCPHCGLSLPEQSEFERHVVGHFLITGSEFNCSSSCGKSFAKSEDLQQHLLSEHVLTLLKCSLCSELCESRMAMQLHLACAHSQETKLLRCSACLELFRSDAEFHVHVKTRHQLGGGHPALGATPSAPANPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGGGGAKDKEQQRGSPNMGSLYVNALLPPLAAAAAAAAATNNNSSIIDYNVAFKGLFGGGAGAGAASGPGSGSGGGSGAAPPSGNKFYSPLQVDTNALKAQTSPHPALMYGLSQRYLMEMYAAKSTSPAGGANEGNPQPPQATAPPSAPPSAAPAAATFSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCAGNFKSRAELEQHMKSCHNSTGKHKCLICDEVFPSPAILAEHKLQHSKVGQSGKCSHCGQPLEDVAAFRAHLSEHGSDGATLPLACICCRQTLHSEFELSLHAKFHTKSASSGGSLQEPVCALCLEPLPDVPVEGPAKLCEKCCRKHNLNGKRGKPSEQQLQAPPPSAGAGSGASFVENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPGGLLNHMAEHGAHSRPYDCSLCPEKFYFRAELEHHQRSHELRPQATRPPMPKVETPSIRNSSPICESPPSRSRSPTINVKQELYETDTVESGAGEDEPEENPQEDEEYIEVEQVPHETRPSEMGSQLERSTSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00548267;
90% Identity: iTF_00488807;
80% Identity: -