Basic Information

Insect: Drosophila mayri
Gene Symbol: L
Assembly: GCA_008042485.1
Location: VNJN01007687.1:25122-31992[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 9.3e-06 0.00065 19.9 2.9 1 23 158 180 158 180 0.98

2 17 0.14 9.8 6.7 7.3 1 23 186 208 186 208 0.97

3 17 1.5e-07 1.1e-05 25.5 3.2 1 23 214 236 214 236 0.99

4 17 1.1e-05 0.0008 19.6 0.4 1 23 242 264 242 264 0.99

5 17 0.011 0.77 10.2 0.2 2 23 348 372 347 372 0.92

6 17 0.0014 0.097 13.0 0.4 2 23 394 416 393 416 0.96

7 17 0.057 4 8.0 0.7 1 23 504 526 504 526 0.97

8 17 0.0038 0.27 11.6 0.1 2 23 534 555 533 555 0.92

9 17 8.6e-05 0.006 16.8 0.4 1 23 563 587 563 587 0.94

10 17 4.6 3.2e+02 2.0 0.9 2 23 623 645 622 645 0.94

11 17 0.0023 0.16 12.3 1.1 1 23 690 713 690 713 0.97

12 17 0.0046 0.32 11.4 1.2 2 23 902 924 901 924 0.96

13 17 0.037 2.6 8.5 0.1 1 23 930 952 930 952 0.92

14 17 0.04 2.8 8.4 0.1 2 23 960 981 959 981 0.96

15 17 0.68 47 4.6 0.5 2 23 1084 1105 1084 1105 0.94

16 17 0.0088 0.62 10.5 0.0 1 23 1115 1137 1115 1137 0.96

17 17 0.00016 0.011 16.0 1.7 1 23 1144 1166 1144 1166 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	9.3e-06	0.00065	19.9	2.9	1	23	158	180	158	180	0.98
2	17	0.14	9.8	6.7	7.3	1	23	186	208	186	208	0.97
3	17	1.5e-07	1.1e-05	25.5	3.2	1	23	214	236	214	236	0.99
4	17	1.1e-05	0.0008	19.6	0.4	1	23	242	264	242	264	0.99
5	17	0.011	0.77	10.2	0.2	2	23	348	372	347	372	0.92
6	17	0.0014	0.097	13.0	0.4	2	23	394	416	393	416	0.96
7	17	0.057	4	8.0	0.7	1	23	504	526	504	526	0.97
8	17	0.0038	0.27	11.6	0.1	2	23	534	555	533	555	0.92
9	17	8.6e-05	0.006	16.8	0.4	1	23	563	587	563	587	0.94
10	17	4.6	3.2e+02	2.0	0.9	2	23	623	645	622	645	0.94
11	17	0.0023	0.16	12.3	1.1	1	23	690	713	690	713	0.97
12	17	0.0046	0.32	11.4	1.2	2	23	902	924	901	924	0.96
13	17	0.037	2.6	8.5	0.1	1	23	930	952	930	952	0.92
14	17	0.04	2.8	8.4	0.1	2	23	960	981	959	981	0.96
15	17	0.68	47	4.6	0.5	2	23	1084	1105	1084	1105	0.94
16	17	0.0088	0.62	10.5	0.0	1	23	1115	1137	1115	1137	0.96
17	17	0.00016	0.011	16.0	1.7	1	23	1144	1166	1144	1166	0.98

Sequence Information

Coding Sequence: ATGATGGCCCTAAAGATGTTATATCGCGGTCCCAGTTCGCGTTTGgagaatttaattgaaaagatCCAGGCCACCAAGGAGATAACCAGTAGCGACATGTATAGTACCCACACATCATCCAGTTACTCGCCTAGCATTTCGGATGGCACCATGACGCCCAATTCCCACCATTTGCCCGGAGCTCCCACCTCCGCCGCTGCCTCTGGCCAGGAGGATCATCATCATTCCGATGGCAAACTCAATGGTGGCACCGATGGCGAAGAGTTGGCCAAACCAAAGCGTTTGCCACACtttcatcaccatcatcatcatcattaccACCATCAGCAGGCGCTGAAAATCGCCAACAAGCTGCGCAAAATCAATAAAGAAGCCAAAATGGGAGCTGGCGGCGGTGCTGGTGCCGGAGGAGCAGGCTCCAAGTTTGATAAGTTGACAGGCGAGGGGATTAAGGCCCGCGGCGACGGCTCCTATCAGTGTCAGTTCTGCGATAAGTCATTTCCGCGTCTCGGCTACTTGAAGCATCACGTACAGAGCCACGCCGAACACCTGCCCTTCAAGTGCGAATACTGCTCGAAGCTGTTCAAGCACAAGCGTTCCCGGGATCGCCACAAGAAGCTGCATACCAACGAGCGTAACTACAAGTGTCCCCATTGCGAGGCGGCCTTCTCCAGGAGTGACCACCTGAAGATCCACATGAAGACCCACGACATCCAGAAGCCGTTCCAGTGCAGCATGTGCAACCGTGGCTATAATACGGCGGCTGCCCTGACCTCGCACATGCAGAAGCACAAGAAGAATGCGGCCATCCTGGCAGCTGGTGGCAATCCCAATGCCCTCAACTATAGTCCCCGCTCGACGGGATCGGCCTCGGCCTCGGTCTCCAGCAATGGCAGTCTGCAGAAGAGGCGATATGCCTTGGCCCTGGCCTCGGATAGTAGTCCCAGTCGGCTGGACTTTCCGAAGAGATCCAGGAGCAGTCATGTGGGTGGAAATGGAGGTAGCACTACCACAACGACAGCCACACCCACTCCCCTGCTGAGGTGCAGCTACTGTCCCAAGGTCACGGAGTTTAGCAGCTTGGAGCAGCTGAATGCCCACCTGCAGAGTGTCcacgagcagcagcatcagcatgcGGCAAAGACACCCATAGCTCCCGAGAGCGAAGGCTTCCAGCTGAGCTGCGAATATTGCACTATGAAATTCGGGAATATCGCCGGATTGTTCCAGCACATGAGGAGCACTCATCTGGACAGATTGAGCAGTCCAAACTCGTACTATGAGCCCTTCAATCGCCTGGCCACTGCTGGCACTTTCAGTCCCCGTTTGGCTTTGGATTTGCCCAAAATCAAACCGGATTTGGGCAGTCCGGAGAGGGAAACAACGCGTGCAGCCGAGGAGGATCTGCCCACCGATTTGAGCAGCAACAAGAGGCGATCCCAGACACCCACAAATAACCAGCAGTTGCAGTCCCAACAGCTGGCACCGCCGGCTGCTCCTCCCGGAGTGTTCTTCTGCAATCAATGCAACGCTGGTCTGCCGGATTTCGAGAGCTTCAGGAATCACCTAAAGAGTCATATAGCTGAGGGCATGCAGATGGTGTGTCCCCACTGCGGATTGAGTCTGCCCGAGCAGTCGGAGTTCGAGCGCCATGTGGTGGGCCACTTCCTCATCACCGGCTCTGAGTTCAACTGCAGCTCCAGCTGCGGCAAGAGCTTTGCCAAGTCGGAGGATCTGCAGCAGCATCTGCTGTCCGACCATGTGCTCACCCTGCTGAAGTGCTCGCTGTGCTCGGAGCTCTGCGAGAGTCGGATGGCCATGCAGCTGCATCTGGCCTGCGCCCATAGCCAGGAGACAAAGCTTCTACGCTGCAGCGCCTGCCTGGAGCTCTTCCGCTCCGATGCCGAGTTCCATGTGCATGTGAAGACGCGCCACCAGCTGGGCGGTCATCCCTCGCTGGGGGCCGCACCCACTGCTCCTGCCAATCCTCTGCAGTGCATGTTCTGCCGGGCTGTCTGCTCCTCAGAGCTAGAGATGCACTTCCATTTGGCGGCGCACGCCAGGCAGTTTAGGTGCCCCTCCTGCCCGGAGACCTTCCATGTGGAGTTCCTGCTGGATAGGCACATGCAGAGCCAGCATGGTGGCGGCGTAAAggacaaggagcagcagcgtgGCTCCCCCAACATGGGCAGTCTCTATGTGAATGCCTTGCTGCCTCCTTTggctgcagcggcggcggcagcagcggccaccaataacaacagcagcatcatTGACTACAATGTGGCTTTCAAGGGTTTGTTTGGCGGCGGAGCAGGCGGAGGAGCGGCATCTGGTGCGGGAtcaggtggaggaggaggctctGGCGGAGCCCCACCATCGGGCAACAAGTTCTACAGTCCCCTGCAGGTGGACACCAATGCCTTGAAGGCTCAAACCTCACCGCATCCCGCTCTCATGTACGGCCTGAGTCAGCGCTATCTGATGGAGATGTATGCCGCCAAGTCCACGTCCCCAGCGGGCGGCAATGAGGGCAATCCACAGCCACCACAGGCTTCAGCTCCGCCGAGTGCTCCACCGAGTGCAGCTCCAGCCACTGCCACCTTCAGTTGTGGCATGTGCGAGCGCCAGGATCTGCGCAGCGAGGCGGAGCTCCATTCGCACCGCAAGCTGGCCCACAATCTCAAGACGGGCGTGAGCCTGAGGTGTGCCTACTGTGCCGGCAACTTCAAGTCTCGGGCTGAGCTGGAGCAGCACATGAAGAGCTGTCACAATTCGACGGGCAAGCACAAGTGCCTGATCTGCGATGAGGTCTTTCCCTCACCGGCCATCCTGGCCGAACACAAGCTGCAGCACTCGAAGGTGGGTCAGTCTGGGAAATGCTCTCACTGCGGCCAACCGCTGGAGGATGTGGCCGCCTTCAAGGCTCATCTCTCGGAGCACGGCAGCGACGGGGCCACCCTGCCGCTGGCCTGCATCTGCTGTCGCCAGACCCTGCACTCGGAGTTCGAGCTGAGCCTGCATGCCAAGTTCCACACCAAGTCGGCCTCGAGCGGTGGTAGCCTCCAGGAGCCGGTGTGTGCTCTGTGCCTGGAGCCGCTGCCCGATGTGCCAGTCGAGGGCCCAGCCAAGCTGTGCGAGAAATGCTGTCGGAAGCATAACCTAAATGGAAAGCGGGGAAAGCCAAGTGACCCACAGCTGCAGGCACCGCCATCAgccggaggagcaggagctgcctTTGTGGAGAACCGCTGCAATCTGTGCAAGATGATCCTGCCGCATGCCCAGAAGCTGCAAGAACACCTGGTGGAGCACACCTTTGCGGGCACCGAGCAGCGCGGCTTCAATTGCTACATTTGCTCGGCGGTTTTCACGGCTCCCGGAGGCCTTCTCAATCACATGGCAGAGCATGGAGCTCACTCGCGTCCCTATGATTGCAGCTTGTGTCCAGAGAAGTTCTACTTCCGGGCGGAGTTGGAGCACCATCAGAGGAGCCACGAGCTGAGGCCCCAGGCCACGAGGCCACCCATGCCCAAGGTGGAGGCGCCCTCCATTAGGAACAGCTCACCCATTTGCGAGAGTCCTCCATCCAGGAGTCGCAGTCCCACAATTAATGTCAAGCAGGAGCTCTACGAAACGGACACTGTGGAGTCGGCAGCAGGAGAAGATGAGCCAGAGGAGAATCCACAAGAAGATGAGGAGTACATAGAAGTGGAGCAGGTGCCGCAGGAGACACGAACCAGTGAAATGGCTTCGCAAATGGAAAGGTCCACCAGTAGCGCCTAA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEITSSDMYSTHTSSSYSPSISDGTMTPNSHHLPGAPTSAAASGQEDHHHSDGKLNGGTDGEELAKPKRLPHFHHHHHHHYHHQQALKIANKLRKINKEAKMGAGGGAGAGGAGSKFDKLTGEGIKARGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCSKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASASVSSNGSLQKRRYALALASDSSPSRLDFPKRSRSSHVGGNGGSTTTTTATPTPLLRCSYCPKVTEFSSLEQLNAHLQSVHEQQHQHAAKTPIAPESEGFQLSCEYCTMKFGNIAGLFQHMRSTHLDRLSSPNSYYEPFNRLATAGTFSPRLALDLPKIKPDLGSPERETTRAAEEDLPTDLSSNKRRSQTPTNNQQLQSQQLAPPAAPPGVFFCNQCNAGLPDFESFRNHLKSHIAEGMQMVCPHCGLSLPEQSEFERHVVGHFLITGSEFNCSSSCGKSFAKSEDLQQHLLSDHVLTLLKCSLCSELCESRMAMQLHLACAHSQETKLLRCSACLELFRSDAEFHVHVKTRHQLGGHPSLGAAPTAPANPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGGVKDKEQQRGSPNMGSLYVNALLPPLAAAAAAAAATNNNSSIIDYNVAFKGLFGGGAGGGAASGAGSGGGGGSGGAPPSGNKFYSPLQVDTNALKAQTSPHPALMYGLSQRYLMEMYAAKSTSPAGGNEGNPQPPQASAPPSAPPSAAPATATFSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCAGNFKSRAELEQHMKSCHNSTGKHKCLICDEVFPSPAILAEHKLQHSKVGQSGKCSHCGQPLEDVAAFKAHLSEHGSDGATLPLACICCRQTLHSEFELSLHAKFHTKSASSGGSLQEPVCALCLEPLPDVPVEGPAKLCEKCCRKHNLNGKRGKPSDPQLQAPPSAGGAGAAFVENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPGGLLNHMAEHGAHSRPYDCSLCPEKFYFRAELEHHQRSHELRPQATRPPMPKVEAPSIRNSSPICESPPSRSRSPTINVKQELYETDTVESAAGEDEPEENPQEDEEYIEVEQVPQETRTSEMASQMERSTSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00548267;
90% Identity: iTF_00488807;
80% Identity: -