Basic Information

Insect: Drosophila persimilis
Gene Symbol: L
Assembly: GCA_003286085.2
Location: NW:7227122-7255800[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 1.4e-05 0.00077 19.4 3.1 1 23 298 320 298 320 0.98

2 18 0.39 22 5.4 6.2 1 23 326 348 326 348 0.97

3 18 1.9e-07 1e-05 25.3 3.2 1 23 354 376 354 376 0.99

4 18 1.4e-05 0.00077 19.4 0.4 1 23 382 404 382 404 0.99

5 18 0.024 1.4 9.2 0.2 2 23 480 504 479 504 0.92

6 18 0.0042 0.24 11.6 0.2 2 23 535 557 534 557 0.95

7 18 0.068 3.8 7.8 0.7 1 23 639 661 639 661 0.97

8 18 0.0057 0.32 11.2 0.1 2 23 669 690 668 690 0.91

9 18 0.0003 0.017 15.2 0.2 1 23 698 722 698 722 0.95

10 18 3 1.7e+02 2.6 0.2 2 20 728 746 727 747 0.93

11 18 1.4 81 3.7 0.9 2 23 758 780 757 780 0.95

12 18 0.0028 0.16 12.2 1.1 1 23 825 848 825 848 0.97

13 18 0.0055 0.31 11.3 1.2 2 23 1030 1052 1029 1052 0.96

14 18 0.13 7.1 7.0 0.1 1 23 1058 1080 1058 1080 0.92

15 18 4.7 2.6e+02 2.0 0.7 2 23 1088 1109 1088 1109 0.95

16 18 0.64 36 4.7 0.9 2 23 1209 1230 1209 1230 0.94

17 18 0.078 4.4 7.6 0.0 1 23 1240 1262 1240 1262 0.96

18 18 0.00024 0.014 15.5 1.2 1 23 1269 1291 1269 1291 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	1.4e-05	0.00077	19.4	3.1	1	23	298	320	298	320	0.98
2	18	0.39	22	5.4	6.2	1	23	326	348	326	348	0.97
3	18	1.9e-07	1e-05	25.3	3.2	1	23	354	376	354	376	0.99
4	18	1.4e-05	0.00077	19.4	0.4	1	23	382	404	382	404	0.99
5	18	0.024	1.4	9.2	0.2	2	23	480	504	479	504	0.92
6	18	0.0042	0.24	11.6	0.2	2	23	535	557	534	557	0.95
7	18	0.068	3.8	7.8	0.7	1	23	639	661	639	661	0.97
8	18	0.0057	0.32	11.2	0.1	2	23	669	690	668	690	0.91
9	18	0.0003	0.017	15.2	0.2	1	23	698	722	698	722	0.95
10	18	3	1.7e+02	2.6	0.2	2	20	728	746	727	747	0.93
11	18	1.4	81	3.7	0.9	2	23	758	780	757	780	0.95
12	18	0.0028	0.16	12.2	1.1	1	23	825	848	825	848	0.97
13	18	0.0055	0.31	11.3	1.2	2	23	1030	1052	1029	1052	0.96
14	18	0.13	7.1	7.0	0.1	1	23	1058	1080	1058	1080	0.92
15	18	4.7	2.6e+02	2.0	0.7	2	23	1088	1109	1088	1109	0.95
16	18	0.64	36	4.7	0.9	2	23	1209	1230	1209	1230	0.94
17	18	0.078	4.4	7.6	0.0	1	23	1240	1262	1240	1262	0.96
18	18	0.00024	0.014	15.5	1.2	1	23	1269	1291	1269	1291	0.97

Sequence Information

Coding Sequence: ATGTCCCGACGCAAACAGGCCAAGCCGCGCGCCTGTCTCAAACTTGGCGAAAAGGAGGAGGAGACACAGCCCAATGTGGGTGACCTGCTGGAGCCCAAGGAGGAGCTGCTCAGTGCGGACGAGGAGGATGGGGAAGAGGACGCCGAGGCGGAGGAGGATGCTGAGGGAGAACTGCTTACCGAGGAGAAGCCACTCAAGCCCAATGAATCACAGCCACAAAGCCACTGGACAACAGCTGATGAGGATCCGGGCCAGGGCTCGGTTGTGCCAaaagaagaagcagaagaagtACAACACCCACGGGATAAGGAAggtcctgctgctggtggtgcatCTGATGCAGCTGCCAATGCCAACGGGCACTGCAAGTCCTCTGGTAACGAAGCGGATGCTGAGAATGCGGAGGAGGAGCCAGAAGACATGGACTTGGATGACGACCTGCTGAGTCTCAGTGGCGAAGAGGACTACGATGATGAAGAGCTGCAGAGTCTCGACAGCTTCTACTCAGACATGTACAGTACCCACACCTCTTCCAGCTACTCACCGAGCATCTCCGATGGTACCCTGACACCCAACTCCCATCATCTGGCCGCTACCTCGGCGAGTGCCGGCCAGGAGGATCCCCACCTGACCGCAGAAGGCAAGTCGAACGGAGTCCCAGGAGAAGAGCCTGCCAAGCCAAAGCGACAGCCGCACttccaccaccaccatcattACCATCACCAGCAGGCCCTGAAGATTGCCAACAAGCTGCGCAAAATCAATAAGGAGGCCAAGATGGCAGCTGCCGGAGGAGCATTAGCCGGAACCGGcgctggcggtggcggtggagCAGCCGCAAAGTTTGATAAGTTGACAGGCGAAGGCATTAAGAGTCGCGGCGACGGCTCCTATCAGTGCCAGTTCTGTGATAAGACGTTTCCGCGTCTCGGATACTTGAAGCATCACGTGCAGAGCCATGCCGAGCATCTGCCCTTCAAGTGCGAGTACTGCGCCAAGTTGTTCAAGCACAAGCGCTCCCGGGATCGCCATAAGAAGCTGCACACGAACGAGCGGAACTACAAGTGCCCGCACTGCGAGGCGGCCTTCTCCAGGAGCGATCACCTGAAGATCCACATGAAGACGCATGACATCCAGAAGCCATTCCAGTGCAGCATGTGCAACAGGGGATACAACACGGCCGCGGCTCTCACCTCACACATGCAGAAGCACAAGAAGAACGCCGCCATCCTGGCCGCCGGCGGCAATCCCAATGCCCTCAACTACAGTCCCCGGTCCACCGGTTCCGCCTCGGCCTCGGTGTCCAGCAATGGGAGCCTGCACAAGCGCCGCTatgccctggccctggccacCGACAGCAGTCCCAGTCGCCTGGACTTCCCCAAGAGATCGCGCAGCAGTCATGTGGGCAGCACGCCCACCCCAACCCCTCTGCTCAGATGCAGCTACTGCCCCAAGGCGACAGAGTTCAGCAGCCTGGAGCAGCTGAATGCCCATCTCCAGAATGTCCAtgagcagccgcagccaccccagcagccacagcagtcacagcagcagcagtcggcGAAGACCCCCGTCCAGGAGGGAGAGGGCTTCCAGCTGAGCTGCGAGTATTGCACCATGAAGTTTGGCAACATTGCCGGACTATTCCAGCACATGCGCGCCACCCATCTGGATCGTCTGAGCAGCCCCAACTCCTACTACGAGCACTTCAATCGCCTGGCCACGGCCGGAACATTCAGTCCACGGCTGGCTCTGGATCTACCCAAGATTAAGACGGATCTGGGCAGTCCCGAGCGTGAGAACCGACCCTCCGAGGACGACCTTCCCACGGATCTGAGCAGCAACAAGCGTCGACCGCAGACACCCAGTGCTCCGCCCAATCCTCCGCACGCAACAGCACCACCCGGCATCTTCTTCTGCAACCAGTGCAACGCTGGACTTCCCGACTTTGAGAGCTTCCGCAACCACCTGAAGAGCCACATTGCCGAAGGAATGCAGCTGATCTGTCCCCACTGTGGCCTGAGCCTCCCGGAGCAGTCCGAGTTCGAGCGGCACGTGGTGGGACACTTCCTGATCGCCAACTCCGAGTTTAactgcagctccagctgcgGCAAGAGCTTTGGCAAGGCcgaggagctgcagcagcacctCATCACCGAGCACGTACTCACCCTGCTGAAGTGCGCCCTCTGTTCGGAGACGTGCGAGACACGGATGGCCATGCAGCTCCACCTGGCCTGCGCCCACAGCCAGGAGACGAAGCTGCTGCGCTGCAGCGCCTGCATGGAGGTCTTCCGTTCCGATGGCGACTTCCATGTGCACGTTAAGACGCGCCATCAGCTGGGGAATCATCACCACCCGATGGGCGGCAACAGCAGTCCGGCCAATCCGCTGCAGTGCATGTTCTGCCGGGCCGTGTGCTCCTCTGAGCTGGAGATGCACTTCCATCTGGCGGCCCATGCGCGACAGTTCCGCTGTCCATCCTGTCCGGAGACCTTCCACGTGGAGTTCCTGCTCGACAGGCACATGCAGAGCCAGCACGGCGGCGTCAAGGACAAAGAGCTGCCGCCACAGAGCTCCCCCAACATGGGTAGTCTCTATGTGAACGCCCTGCTGCCTCCCCTCGccgcagctgccgctgccgcagctgccaccaacaacaacagtagcATCATCGACTACAACGTGGCCTTCAAGGGGTTGTTCGGTGGAGGATCAACAGGAGGGAATGCACCCACAGGTCCCTCGGCGGCCGGCAAGTTCTACAGCCCCTTGCAGGTGGAAACGAATGCCCTGAAGACACAGACCTCGCCCCATCCCGCCCTGATGTACGGCCTCAGCCAGCGCTATCTGATGGAGATGTACGCTGCCAAGTCGACGTCACCGGCCAACAGTGCCGCCAACGAATCAGCAGGAGGAGGAACCTCCTCCATCAATGCCCCGCCAGCACCACAGGCGCCGCCACCTCCCGCACCAGCTGTCACATTCAGCTGTGGGATGTGCGAGCGTCAGGATCTGCGCAGCGAGGCGGAACTCCACTCACACCGGAAGCTGGCCCACAACCTGAAGACGGGCGTGAGTCTGCGGTGCGCCTACTGTGCGGGCAACTTCAAGTCGCGGGCGGAGCTCGAGCAGCACATGAAGAGCTGCCACAACTCGACGGGCAAGCACAAGTGCCTCATCTGCGACGAGATCTTCCCCTCGCCGGCCATCCTGGCCGAGCACAAGCTCCAGCACTCGAAGGTGGGTCAATCGGGCAAGTGCGCCCACTGCAGCCACCCGTTGGAGGATGTGGTCGCCTTCCGAGCCCATCTCAGCGAGCATGGCAGCGATGGAGCCTCCCTGCCCCTGGCCTGCATTTGTTGTCGCCAGACACTTCACTCGGAGTTCGAGCTGAGCCTCCATGCCAAGTTCCATACGAAGTCCTCGTCCAGTGGCGGCTGCCTCCAAGAACCAGCTTGCGCCCTGTGCCTGGAGCCCCTGCCAGGGGCAGTGGAGGGACCCACCACTCCGGCCAAGCTCTGCGAAAAGTGCTGCCGCAAGCACAACCTCAACGGCAAGCGGAACAAGGCCAGCGAAGCCCCCGTGGTCCAGGCCCAGCCGACTCCCTACCTGGAGAACCGCTGCAACCTGTGCAAGATGATCTTGCCGCATTCCCAGAAACTGCAGGAGCACCTGGTCGAGCACACCTTCGCCGGCACCGAGCAGCGAGGCTTTAATTGCTACATCTGTTCGGCCGTGTTCACAGCCCCTGGCGGCCTCCTTGGCCACATGGCCGAGCACGGCGCCCACTCGCGTCCCTACGACTGCAATCTCTGCCCCGAGAAGTTCTACTTCCGCGCCGAGCTGGAACACCACCAGCGGGCACACGAGCTGAGGCCAACGGTTCGTCCAACGCTCACCAAGCCGGAGCCCCCGATGCGGGGCAGTGCATCGCCCAGTCCAAGTCCGGTTCGAAGTCCCGCGACCGTGAAGCAGGAGCTGTACGACACGGATACGGGTCACTCTGGGGGCGGCGATGATGAGCCAGAGCCCGCCCAGGATGAGGAGGAGTACATAGAGGTGGAGCAGATTCCGCACGAGACGCGGCCAAGGGATGTCGTGTCACAGATGGAAAGGGCCACAAACAGCGCCTGA
Protein Sequence: MSRRKQAKPRACLKLGEKEEETQPNVGDLLEPKEELLSADEEDGEEDAEAEEDAEGELLTEEKPLKPNESQPQSHWTTADEDPGQGSVVPKEEAEEVQHPRDKEGPAAGGASDAAANANGHCKSSGNEADAENAEEEPEDMDLDDDLLSLSGEEDYDDEELQSLDSFYSDMYSTHTSSSYSPSISDGTLTPNSHHLAATSASAGQEDPHLTAEGKSNGVPGEEPAKPKRQPHFHHHHHYHHQQALKIANKLRKINKEAKMAAAGGALAGTGAGGGGGAAAKFDKLTGEGIKSRGDGSYQCQFCDKTFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASASVSSNGSLHKRRYALALATDSSPSRLDFPKRSRSSHVGSTPTPTPLLRCSYCPKATEFSSLEQLNAHLQNVHEQPQPPQQPQQSQQQQSAKTPVQEGEGFQLSCEYCTMKFGNIAGLFQHMRATHLDRLSSPNSYYEHFNRLATAGTFSPRLALDLPKIKTDLGSPERENRPSEDDLPTDLSSNKRRPQTPSAPPNPPHATAPPGIFFCNQCNAGLPDFESFRNHLKSHIAEGMQLICPHCGLSLPEQSEFERHVVGHFLIANSEFNCSSSCGKSFGKAEELQQHLITEHVLTLLKCALCSETCETRMAMQLHLACAHSQETKLLRCSACMEVFRSDGDFHVHVKTRHQLGNHHHPMGGNSSPANPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGVKDKELPPQSSPNMGSLYVNALLPPLAAAAAAAAATNNNSSIIDYNVAFKGLFGGGSTGGNAPTGPSAAGKFYSPLQVETNALKTQTSPHPALMYGLSQRYLMEMYAAKSTSPANSAANESAGGGTSSINAPPAPQAPPPPAPAVTFSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCAGNFKSRAELEQHMKSCHNSTGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCSHPLEDVVAFRAHLSEHGSDGASLPLACICCRQTLHSEFELSLHAKFHTKSSSSGGCLQEPACALCLEPLPGAVEGPTTPAKLCEKCCRKHNLNGKRNKASEAPVVQAQPTPYLENRCNLCKMILPHSQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPGGLLGHMAEHGAHSRPYDCNLCPEKFYFRAELEHHQRAHELRPTVRPTLTKPEPPMRGSASPSPSPVRSPATVKQELYDTDTGHSGGGDDEPEPAQDEEEYIEVEQIPHETRPRDVVSQMERATNSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00548267;
90% Identity: iTF_00581014;
80% Identity: -