Basic Information

Insect: Drosophila ananassae
Gene Symbol: L
Assembly: GCA_017639315.1
Location: CM029942.1:14781491-14788038[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 3e-05 0.0023 18.2 2.9 1 23 157 179 157 179 0.98

2 17 0.13 10 6.7 7.3 1 23 185 207 185 207 0.97

3 17 1.4e-07 1.1e-05 25.5 3.2 1 23 213 235 213 235 0.99

4 17 1.1e-05 0.00082 19.6 0.4 1 23 241 263 241 263 0.99

5 17 0.01 0.79 10.2 0.2 2 23 345 369 344 369 0.92

6 17 0.0013 0.099 13.1 0.4 2 23 390 412 389 412 0.96

7 17 0.053 4 8.0 0.7 1 23 491 513 491 513 0.97

8 17 0.0055 0.42 11.1 0.1 2 23 521 542 520 542 0.92

9 17 3.6e-05 0.0028 17.9 0.5 1 23 550 574 550 574 0.95

10 17 4.3 3.3e+02 2.0 0.9 2 23 610 632 609 632 0.94

11 17 0.0022 0.17 12.3 1.1 1 23 678 701 678 701 0.97

12 17 0.0043 0.33 11.4 1.2 2 23 888 910 887 910 0.96

13 17 0.034 2.6 8.6 0.1 1 23 916 938 916 938 0.92

14 17 0.041 3.2 8.3 0.1 2 23 946 967 945 967 0.96

15 17 0.63 49 4.6 0.5 2 23 1071 1092 1071 1092 0.94

16 17 0.011 0.8 10.2 0.0 1 23 1102 1124 1102 1124 0.96

17 17 0.0002 0.015 15.6 1.2 1 23 1131 1153 1131 1153 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	3e-05	0.0023	18.2	2.9	1	23	157	179	157	179	0.98
2	17	0.13	10	6.7	7.3	1	23	185	207	185	207	0.97
3	17	1.4e-07	1.1e-05	25.5	3.2	1	23	213	235	213	235	0.99
4	17	1.1e-05	0.00082	19.6	0.4	1	23	241	263	241	263	0.99
5	17	0.01	0.79	10.2	0.2	2	23	345	369	344	369	0.92
6	17	0.0013	0.099	13.1	0.4	2	23	390	412	389	412	0.96
7	17	0.053	4	8.0	0.7	1	23	491	513	491	513	0.97
8	17	0.0055	0.42	11.1	0.1	2	23	521	542	520	542	0.92
9	17	3.6e-05	0.0028	17.9	0.5	1	23	550	574	550	574	0.95
10	17	4.3	3.3e+02	2.0	0.9	2	23	610	632	609	632	0.94
11	17	0.0022	0.17	12.3	1.1	1	23	678	701	678	701	0.97
12	17	0.0043	0.33	11.4	1.2	2	23	888	910	887	910	0.96
13	17	0.034	2.6	8.6	0.1	1	23	916	938	916	938	0.92
14	17	0.041	3.2	8.3	0.1	2	23	946	967	945	967	0.96
15	17	0.63	49	4.6	0.5	2	23	1071	1092	1071	1092	0.94
16	17	0.011	0.8	10.2	0.0	1	23	1102	1124	1102	1124	0.96
17	17	0.0002	0.015	15.6	1.2	1	23	1131	1153	1131	1153	0.97

Sequence Information

Coding Sequence: ATGATGGCCTTAAAGATGTTATACCGCGGTCCCAGTTCGCGTTTGGAGAATTTAATTGAAAAGATCCAGGCCACCAAGGAGATAACCAATAACGATATGTACAGTACTCACACATCGTCCAGCTACTCACCCAGCATTTCGGACGGCACCATGACTCCCAACTCACACCACTTGCCCGGAGCACCGGCCAGTCTCCCTGGCCAGGATCAGGATCATCCTAGCGAGGGAAGCACCAATGGCGGATTGGATGGCGAGGTCGACTTGGTTAAGCCGAAGCGTCTGCCCCATTTCCATCATCATCACCACCACCACTACCACCACCAGCAGGCGCTAAAAATCGCCAACAAGCTGCGGAAAATCAATAAGGAAGCGAAGATGGGAGCCCTGGGAGGGGCTGGAGCCGGAGGAGCTGGCTCCAAGTTTGATAAGTTGACGGGCGAGGGGATTAAAAGTCGCGGCGACGGCTCCTATCAGTGTCAGTTCTGCGAGAAGTCATTTCCGCGTCTCGGCTACTTGAAGCATCACGTGCAGAGCCACGCCGAACACCTGCCCTTCAAGTGCGAGTACTGCTCCAAGCTCTTCAAGCACAAGCGCTCCCGGGATCGTCATAAGAAATTGCACACCAACGAGAGGAACTACAAGTGTCCCCATTGCGAGGCGGCCTTCTCCAGGAGTGACCATCTTAAGATCCACATGAAAACCCATGACATCCAGAAGCCCTTCCAGTGCAGCATGTGCAACAGGGGCTACAACACTGCCGCTGCCCTGACCTCTCACATGCAAAAGCACAAGAAGAACGCCGCCATCCTTGCAGCTGGAGGCAACCCCAACGCCCTCAACTACAGTCCACGTTCCACGGGATCGGCATCTGCTTCGGTTTCCAGCAACGGGAGCCTGCACAAAAGGCGGTATGCTCTGGCCCTGGCCACGGACAGCAGTCCCAGTCGCCTGGACTACCCCCAGAAGAGATCGAGGAGTGGCACCACCACCACTGCCGCCGCCACAGCTAATGCTACGCCCACGCCCCTGCTAAGGTGCAGCTACTGCCCCAAGGTGACGGAGTTCAGCAGCCTGGAGCAGTTGAATGCGCACTTGCAGAGTGTCCACGAGCAGCAACAGCAGCCCCCGGTGAAGACTCCCAACCAGGAGGCGGAGGGCTTCCAGCTGAGCTGCGAATACTGCACCATGAAGTTCGGCAACATAGCCGGCCTCTTCCAGCACATGCGGAGCACCCACCTGGACAGGCTGAGCAGCCCCAACTCCTACTACGAGCACTTCAACCGCCTGGCCACCGCCGGCACCTTCAGCCCGCGCCTGGCCCTGGATCTGCCCAAGATTAAGCCGGACTTGGGAAGCCCCGATCAGCGGGAGCTGCGGCCGGCGGAGGAGGACCTGCCCACGGACTTGAGCAGCAACAAACGGCGACCCCTGACCCCGAACCCGCAGCCACCACCAGCTCCGCCGGGCGTCTTCTTCTGCAATCAGTGCAACGCCGGCTTGCCGGACTTCGAGAGCTTCAGGAATCACCTGAAGAGCCACCTCGCCGAGGGCATGCAGCAGGTCTGCCCGCACTGTGGGGTCAGCCTGCCGGAGCAGTCGGAGTTCGAGCGCCATGTGGTGGGCCACTTCCTGATCACCGGATCCGAGTTCAACTGCAGCTCCAGCTGCGGCAAGAGCTTCGCCAAGTCGGAGGACCTCCAGCAGCACCTTCTCACCGAGCACGTCCTCACTCTCCTGAAGTGCTCCCTGTGCTCGGAGCTCTGCGAGAGCCGGATGGCCATGCAGCTCCACCTCGCCTGTGCCCACAGCCAGGAAACCAAGCTGCTGCGCTGCAGCGCCTGCCTGGAACTGTTCCGGTCGGATGCCGAGTTCCATGTGCACGTGAAGACGCGCCACCAGCTGGGCGGTCATCCGGCCCTGGGCGGTGCCACTGCCAACACCCCCTCCAATCCTCTACAGTGCATGTTTTGCCGAGTGGTCTGCTCCTCGGAGCTCGAGATGCACTTCCATCTGGCGGCCCATGCCCGGCAGTTCCGGTGCCCGTCGTGCCCCGAGACCTTCCACGTCGAGTTCCTCCTCGATCGTCACATGCAGAGTCAGCACGGCGGAGGTGCGGGTGTCAAGGACAAAGAGGCCAGTTCGCCCAACATGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGGCGTTCAAGGGATTGTTTGGCGGAGCAGCCGGAGGCGGGGGAGGAGGGTCAGGAGCACCCACGGCCCCCTCGTCGAAGTTCTACAGCCCGTTGCAGGTGGACACCAATGCCCTGAAGGCACAGACCTCGTCCCATCCCGCCCTGATGTACGGGCTGAGTCAGAGATACTTGATGGAGATGTACGCCGCCAAGTCGGCCTCTCCGCCGGGAAGCGAGGGAGGAGCAAGTGGCCAGGCAGTCGGCAGTCAGGCAGCCGCTGCAGCAGCACCACCACCCCCTCCTCCGGCACCCCAGCAGGCGCCACCCACCACTTTCAGTTGTGGGATGTGCGAGCGCCAGGATCTGAGGAGCGAGGCGGAACTCCACTCGCACCGAAAACTGGCCCACAACCTGAAGACCGGAGTGAGCCTTAGGTGCGCCTACTGCGCCGGAAACTTCAAGTCGCGAGCCGAGTTGGAGCAGCACATGAAGAGCTGCCACAACTCCACGGGCAAGCATAAGTGCTTGATCTGCGACGAGGTGTTCCCCTCGCCGGCCATCCTGGCGGAGCACAAGCTGCAGCACTCCAAGGTGGGGCAGTCGGGCAAGTGCTCGCACTGCGGCCAGCCCCTGGAGGACGTGGCGGCCTTCCGGGCCCACCTCTCCGAGCACGGCAGCGACGGGGCCTCCCTGCCCCTGGCCTGCATCTGCTGCCGCCAGACCCTGCACTCCGAGTTCGAGCTGAGTCTGCACGCCAAGTTCCACACCAAGTCCGCGTCCAGTGGTGGTAGCCTCCAGGAGCCAGTCTGCGCCCTATGCCTGGAGCCCCTGCCGGACGCCACCGAGGGTCCTGCCAAGCTTTGCGAGAAGTGCTGCCGGAAGCACAACCTCAACGGGAAGAGGAGCAAGCCACCGAGTGAGCCGCCAGTCCAGAGTCTGCAGCCCATCCAGCCCCCATCCGGGGCAGCCTTCGTGGAGAACCGATGCAACCTGTGCAAGATGATCCTGCCGCACGCCCAGAAGCTGCAAGAGCACCTGGTGGAGCACACCTTTGCCGGCACCGAGCAGCGCGGCTACAATTGCTACATCTGCTCCGCGGTCTTCACGGCCGCCGGTGGCCTCCTCAACCACATGGCGGAGCACGGTGCCCATACGCGTCCCTACGACTGCAACCTCTGCCCGGAGAAGTTCTACTTCCGGGCGGAGCTGGAGCACCACCAGCGTGGCCACGAGCTGCGGCCCCAGGCACGACCCAAGATGGAAGTGCCCTCGAACCGGACCAGTTCCTCGCCCATCGACAGTCCCGTGAGGAGTCCCACGATCGTCAAGCAGGAGCTGTACGAGACGGATACAGCCCAGTCGGCCGGAGGGGATGAGGACGAGCCGGAGAACGCGCACGAGGACGAGGAGTACATCGAGGTGGAGCAAATGCCGCACGAGGGGCGTCCCAGTGACTTGGAAAGGGCCACCAGTAGCGCCTAA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEITNNDMYSTHTSSSYSPSISDGTMTPNSHHLPGAPASLPGQDQDHPSEGSTNGGLDGEVDLVKPKRLPHFHHHHHHHYHHQQALKIANKLRKINKEAKMGALGGAGAGGAGSKFDKLTGEGIKSRGDGSYQCQFCEKSFPRLGYLKHHVQSHAEHLPFKCEYCSKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASASVSSNGSLHKRRYALALATDSSPSRLDYPQKRSRSGTTTTAAATANATPTPLLRCSYCPKVTEFSSLEQLNAHLQSVHEQQQQPPVKTPNQEAEGFQLSCEYCTMKFGNIAGLFQHMRSTHLDRLSSPNSYYEHFNRLATAGTFSPRLALDLPKIKPDLGSPDQRELRPAEEDLPTDLSSNKRRPLTPNPQPPPAPPGVFFCNQCNAGLPDFESFRNHLKSHLAEGMQQVCPHCGVSLPEQSEFERHVVGHFLITGSEFNCSSSCGKSFAKSEDLQQHLLTEHVLTLLKCSLCSELCESRMAMQLHLACAHSQETKLLRCSACLELFRSDAEFHVHVKTRHQLGGHPALGGATANTPSNPLQCMFCRVVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGGAGVKDKEASSPNMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAFKGLFGGAAGGGGGGSGAPTAPSSKFYSPLQVDTNALKAQTSSHPALMYGLSQRYLMEMYAAKSASPPGSEGGASGQAVGSQAAAAAAPPPPPPAPQQAPPTTFSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCAGNFKSRAELEQHMKSCHNSTGKHKCLICDEVFPSPAILAEHKLQHSKVGQSGKCSHCGQPLEDVAAFRAHLSEHGSDGASLPLACICCRQTLHSEFELSLHAKFHTKSASSGGSLQEPVCALCLEPLPDATEGPAKLCEKCCRKHNLNGKRSKPPSEPPVQSLQPIQPPSGAAFVENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGYNCYICSAVFTAAGGLLNHMAEHGAHTRPYDCNLCPEKFYFRAELEHHQRGHELRPQARPKMEVPSNRTSSSPIDSPVRSPTIVKQELYETDTAQSAGGDEDEPENAHEDEEYIEVEQMPHEGRPSDLERATSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00548267;
90% Identity: iTF_00615690;
80% Identity: -