Basic Information

Insect: Drosophila yakuba
Gene Symbol: L
Assembly: GCA_016746365.1
Location: NC:12852907-12883899[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 7.5e-05 0.0045 17.8 3.0 1 23 298 320 298 320 0.98

2 17 0.27 16 6.6 7.3 1 23 326 348 326 348 0.97

3 17 2.9e-07 1.8e-05 25.3 3.2 1 23 354 376 354 376 0.99

4 17 2.2e-05 0.0013 19.5 0.4 1 23 382 404 382 404 0.99

5 17 0.021 1.3 10.1 0.2 2 23 484 508 483 508 0.92

6 17 0.0067 0.41 11.6 0.2 2 23 530 552 529 552 0.95

7 17 0.11 6.5 7.8 0.7 1 23 636 658 636 658 0.97

8 17 0.0089 0.54 11.2 0.1 2 23 666 687 666 687 0.92

9 17 7.4e-05 0.0045 17.8 0.5 1 23 695 719 695 719 0.95

10 17 8.7 5.3e+02 1.8 0.9 2 23 755 777 754 777 0.94

11 17 0.0044 0.27 12.2 1.1 1 23 822 845 822 845 0.97

12 17 0.0086 0.52 11.3 1.2 2 23 1027 1049 1026 1049 0.96

13 17 0.07 4.2 8.4 0.1 1 23 1055 1077 1055 1077 0.92

14 17 0.084 5.1 8.2 0.1 2 23 1085 1106 1084 1106 0.96

15 17 1.3 78 4.4 0.5 2 23 1204 1225 1204 1225 0.94

16 17 0.017 1 10.4 0.0 1 23 1235 1257 1235 1257 0.96

17 17 0.00059 0.036 14.9 1.2 1 23 1264 1286 1264 1286 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	7.5e-05	0.0045	17.8	3.0	1	23	298	320	298	320	0.98
2	17	0.27	16	6.6	7.3	1	23	326	348	326	348	0.97
3	17	2.9e-07	1.8e-05	25.3	3.2	1	23	354	376	354	376	0.99
4	17	2.2e-05	0.0013	19.5	0.4	1	23	382	404	382	404	0.99
5	17	0.021	1.3	10.1	0.2	2	23	484	508	483	508	0.92
6	17	0.0067	0.41	11.6	0.2	2	23	530	552	529	552	0.95
7	17	0.11	6.5	7.8	0.7	1	23	636	658	636	658	0.97
8	17	0.0089	0.54	11.2	0.1	2	23	666	687	666	687	0.92
9	17	7.4e-05	0.0045	17.8	0.5	1	23	695	719	695	719	0.95
10	17	8.7	5.3e+02	1.8	0.9	2	23	755	777	754	777	0.94
11	17	0.0044	0.27	12.2	1.1	1	23	822	845	822	845	0.97
12	17	0.0086	0.52	11.3	1.2	2	23	1027	1049	1026	1049	0.96
13	17	0.07	4.2	8.4	0.1	1	23	1055	1077	1055	1077	0.92
14	17	0.084	5.1	8.2	0.1	2	23	1085	1106	1084	1106	0.96
15	17	1.3	78	4.4	0.5	2	23	1204	1225	1204	1225	0.94
16	17	0.017	1	10.4	0.0	1	23	1235	1257	1235	1257	0.96
17	17	0.00059	0.036	14.9	1.2	1	23	1264	1286	1264	1286	0.97

Sequence Information

Coding Sequence: ATGTCCCGACGCAAACAGGCCAAGCCGCGCGCCTGTCTCAAACTTGGCGAGAAGGAGGATGAGGAGAACACCGGACTGCTGGAGCCCAAGGAGGAGCTGCTCAGCGGCGACGAGGACAACGAGGATAATGAGGACGAcaacgaggacgaggaggtgGCTGATGAGGTGGCGCCCGAGGGAGGAGGGGGACAAGAGCCGCCCCAGCTCGAGCCCAATGAATCACAGCAACAAAGCTGGCCAACAGCTGATGAGCCAGCGGCCCCAGCTGCAGTGGCAAAAGAAGAAGAACTCGGAGAGGAAGAGAAAGAGATAGGGGAAGGATCAGAAGAACTACAACACCCACGGGATGAGGTAGTTGCATCTGATGCTGCTGCCAATGCCAACGGACACTGCAAGTCCTCTGGCCACGACGAAGATGTGGTGGATGCGGAGGAGCCGGAGGATCTAGACCTGGACGACGAGCTACTCAGTCTCAGCGGGGACGAGGACTACGACGATGAGGAGTTGCAGAGCCTGGACAGCTTTTACTCAGATATGTACAGTACCCACACATCGTCCAGTTATTCGCCTAGCATCTCGGACGGCACCATGACGCCCAATTCACACCACTTGCCCGGAGTTCCTACCGCCGCCGGTCAGGAGGATCATCCCACTGAGGGCAAGATCAATGGTGGTGCTGATGGCGAGGATTTGCCGAAGCCAAAGCGTTTGCCACACTtccatcaccaccaccatcaccattacCACCATCAGCAGGCGCTGAAAATAGCCAACAAGCTGCGCAAAATCAATAAGGAAGCCAAAATGGGAGCCACCGCAGGATCCACTGGAGCAGCATCCAAGTTTGATAAGTTGACAGGAGAGGGGATTAAAAGTCGCGGCGACGGCTCCTACCAGTGCCAGTTCTGCGAAAAGACATTTCCGCGTCTCGGCTACTTGAAGCATCACGTGCAGAGCCACGCCGAACACCTGCCTTTTAAATGCGAATACTGCTCCAAGCTCTTCAAGCACAAGCGCTCCCGAGATCGCCATAAGAAACTGCATACCAACGAGCGGAACTACAAGTGTCCGCATTGCGAGGCAGCCTTTTCCAGGAGTGACCACTTGAAGATCCACATGAAGACCCATGACATTCAGAAGCCCTTCCAGTGCAGCATGTGCAACAGGGGCTACAACACAGCTGCCGCCCTCACCTCGCACATGCAAAAGCACAAGAAGAACGCCGCCATCCTGGCAGCCGGTGGCAATCCGAATGCCCTCAACTACAGTCCACGGTCCACGGGATCGGCCTCGGCATCGGTGTCCAGCAATGGTAGTCTGCAGAAGCGGAGATATGCCCTGGCTCTGGCATCGGACAGCAGTCCCAGTAGACTGGATTTCCCCAAGAGATCGCGGAGTAATCAAGTGGgcggcaccaccaccaccactgccaCACCCACGCCGCTGCTCAGGTGCAGCTACTGTCCCAAGGTCACGGAGTTCAGCAGCCTGGAGCAACTGAATGCCCATCTGCAGAGTGTCCACGAGCAGCCACAACAGGCCGTGAAGACGCCGGTTCAGACGCCGGAGGGCGAAGGCTTCCAGCTGAGCTGTGAGTACTGCACCATGAAGTTTGGCAATATCGCCGGACTCTTTCAGCACATGCGAGGCACTCACATGGACCGACTGAGTAGTCCAAACTCCTACTACGAGCACTTCAATCGCCTGGCCACCGTTGGCACTTTCAGTCCCCGCCTGGCATTGGACTTGCCCAAAATTAAGCCGGACTTGGGAAGTCCGGAGCGGGAATCGCGACCGCCAGAGGACGATCTGCCCACGGATTTGAGCAGCAACAAGCGACGGCCACTGACACCCAATGCCCAAGTGCCGACTCCACTGGCTCCACCCACTGGACCGCCGGGCGTGTTCTTCTGCAATCAGTGCAACGCTGGACTGCCGGATTTCGAGAGCTTTCGGAACCATCTGAAGAGTCACATTGCCGAGGGCATGCAGCCGGTTTGTCCGCACTGCGGATTGAGTTTGCCGGAGCAGTCGGAGTTTGAGCGTCATGTGGTGGGACACTTTCTCATCACGGGCTCGGAGTTCAACTGCAGCTCGAGCTGCGGAAAGAGTTTCGCCAAATCGGAGGATCTGCAGCAACATTTACTCACGGAGCACGTCCTTACCCTGCTGAAGTGTTCCTTGTGCTCGGAGCTCTGCGAAAGCCGGATGGCCATGCAGCTGCATCTGGCCTGTGCCCACAGTCAGGAGACCAAGCTGCTGCGCTGCAGCGCCTGTCTGGAGCTCTTCCGCTCCGACGCCGAGTTCCATGTGCATGTGAAGACGCGTCATCAGTTGGGCGGCCaccccacgttgggcgccacttCTAATGCGCCCACCAATCCGCTGCAGTGCATGTTCTGCCGTGCAGTTTGCTCGTCCGAGCTGGAAATGCACTTCCATTTGGCCGCACATGCACGTCAGTTCCGGTGTCCTTCCTGCCCGGAGACCTTCCACGTGGAGTTTCTGCTGGACCGTCACATGCAGAGTCAGCATGGTGGCGTCAAGGACAAGGAGGCTAGCTCGCCCAACATGGGCAGTCTCTATGTGAATGCCTTGCTGCCTCCTttggcggcagcggcggcggcagcagcggccacaaacaacaacagcagcatcatcgACTACAATGTGGCATTCAAGGGTTTATTTGGAGCAGCTTCCGGGGCAGCCGGATcgggcggaggaggaggagcgcaAGCTGGTGGTGCACCACCATCGGCGAACAAATTCTACAGCCCTCTGCAGGTGGACACCAATGCACTGAAGGCGCAAACCTCTCCGCATCCGGCTCTAATGTACGGCCTCAGTCAGCGGTATCTGATGGAGATGTATGCCGCCAAGTCCACATCGCCCTCGGGCAACGAGGGAATGGGAAACTCGCAGCCAGCGGCTCCTCAAGCAACCGCACCGCCACCACCAAGTGCCAGCACTGCCACCTTCAGTTGCGGAATGTGCGAACGACAGGACTTGCGCAGCGAGGCGGAACTGCACTCCCATCGCAAGTTGGCCCACAACCTGAAGACGGGCGTTAGTCTGAGATGTGCCTACTGTGCGGGCAACTTTAAGTCGAGGGCCGAACTGGAGCAGCACATGAAGAGCTGTCACAACTCGACGGGCAAGCACAAGTGCTTGATATGCGACGAGGTGTTTCCCTCGCCAGCCATCCTGGCCGAGCACAAGCTCCAGCACTCGAAGGTGGGTCAGTCCGGCAAGTGCTCCCACTGCGGACAGCCCCTGGAGGATGTGGCCGCCTTTAGGGCGCATCTATCGGAACATGGAAGCGATGGCGCCTCCTTGCCACTAGCCTGCATTTGCTGCCGCCAGACGTTGCACTCGGAATTCGAGCTGAGTCTGCATGCCAAATTCCACACAAAGTCCTCATCGAGCGGAGGCAGTCTGCAGGAGCCAGTGTGTGCTCTGTGCCTGGAACCACTACCAGATGCCACCGAGGGTCCGGCCAAACTCTGTGACAAGTGCTGCCGCAAGCACAACCTAAATGGCAAACGTGGCAAGCACTCCGAGCCTCAGACATCTCTGCCAGCTCCGCCGTCGGCGTTTGTGGAGAACCGCTGCAACCTGTGCAAGATGATCCTGCCACATGCCCAGAAGCTCCAGGAACACCTGGTGGAGCACACCTTTGCCGGCACCGAGCAGCGCGGCTTCAACTGCTACATCTGCTCGGCCGTTTTCACCGCACCCGGAGGACTCCTGAACCACATGGCCGAACACGGAGCCCATTCGCGACCCTACGACTGCAGTCTCTGCCCGGAGAAATTCTACTTCCGAGCCGAGCTGGAGCACCACCAAAGGGGTCATGAGCTGCGACCACAGGCACGACCTCCAGCACCGAAAGTGGAGGTGCCATCCATGCGGAACAGCTCACCCGGCCAGAGTCCGGTGAGGAGTCCCACCATTGTCAAACAGGAGCTGTACGAAACGGACACAGTGGAGTCTGCCGGAGTGGAAGATGAGCCGGGGAATGCTCCAGATGAGGAGGAGTACATTGAAGTGGAACAAATGCCGCATGAGACACGTCCAAGTGAGATTGGGTCGCAATTGGAAAGGTCCACCAGCAGCGCCTAA
Protein Sequence: MSRRKQAKPRACLKLGEKEDEENTGLLEPKEELLSGDEDNEDNEDDNEDEEVADEVAPEGGGGQEPPQLEPNESQQQSWPTADEPAAPAAVAKEEELGEEEKEIGEGSEELQHPRDEVVASDAAANANGHCKSSGHDEDVVDAEEPEDLDLDDELLSLSGDEDYDDEELQSLDSFYSDMYSTHTSSSYSPSISDGTMTPNSHHLPGVPTAAGQEDHPTEGKINGGADGEDLPKPKRLPHFHHHHHHHYHHQQALKIANKLRKINKEAKMGATAGSTGAASKFDKLTGEGIKSRGDGSYQCQFCEKTFPRLGYLKHHVQSHAEHLPFKCEYCSKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASASVSSNGSLQKRRYALALASDSSPSRLDFPKRSRSNQVGGTTTTTATPTPLLRCSYCPKVTEFSSLEQLNAHLQSVHEQPQQAVKTPVQTPEGEGFQLSCEYCTMKFGNIAGLFQHMRGTHMDRLSSPNSYYEHFNRLATVGTFSPRLALDLPKIKPDLGSPERESRPPEDDLPTDLSSNKRRPLTPNAQVPTPLAPPTGPPGVFFCNQCNAGLPDFESFRNHLKSHIAEGMQPVCPHCGLSLPEQSEFERHVVGHFLITGSEFNCSSSCGKSFAKSEDLQQHLLTEHVLTLLKCSLCSELCESRMAMQLHLACAHSQETKLLRCSACLELFRSDAEFHVHVKTRHQLGGHPTLGATSNAPTNPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGVKDKEASSPNMGSLYVNALLPPLAAAAAAAAATNNNSSIIDYNVAFKGLFGAASGAAGSGGGGGAQAGGAPPSANKFYSPLQVDTNALKAQTSPHPALMYGLSQRYLMEMYAAKSTSPSGNEGMGNSQPAAPQATAPPPPSASTATFSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCAGNFKSRAELEQHMKSCHNSTGKHKCLICDEVFPSPAILAEHKLQHSKVGQSGKCSHCGQPLEDVAAFRAHLSEHGSDGASLPLACICCRQTLHSEFELSLHAKFHTKSSSSGGSLQEPVCALCLEPLPDATEGPAKLCDKCCRKHNLNGKRGKHSEPQTSLPAPPSAFVENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPGGLLNHMAEHGAHSRPYDCSLCPEKFYFRAELEHHQRGHELRPQARPPAPKVEVPSMRNSSPGQSPVRSPTIVKQELYETDTVESAGVEDEPGNAPDEEEYIEVEQMPHETRPSEIGSQLERSTSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00548267;
90% Identity: iTF_00504840;
80% Identity: -