Basic Information

Insect: Drosophila subsilvestris
Gene Symbol: L
Assembly: GCA_035043285.1
Location: JAWNNB010001922.1:3211847-3218849[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 1.4e-05 0.00098 19.6 3.1 1 23 159 181 159 181 0.98

2 18 0.38 27 5.6 6.2 1 23 187 209 187 209 0.97

3 18 1.8e-07 1.3e-05 25.4 3.2 1 23 215 237 215 237 0.99

4 18 1.4e-05 0.00097 19.6 0.4 1 23 243 265 243 265 0.99

5 18 0.024 1.7 9.3 0.2 2 23 341 365 340 365 0.92

6 18 0.0042 0.3 11.7 0.2 2 23 397 419 396 419 0.95

7 18 0.067 4.8 7.9 0.7 1 23 500 522 500 522 0.97

8 18 0.005 0.36 11.5 0.1 2 23 530 551 529 551 0.91

9 18 0.0028 0.2 12.3 0.1 1 23 559 583 559 583 0.94

10 18 4 2.8e+02 2.4 0.1 2 20 589 607 588 608 0.92

11 18 1.4 1e+02 3.8 0.9 2 23 619 641 618 641 0.95

12 18 0.0028 0.2 12.3 1.1 1 23 702 725 702 725 0.97

13 18 0.0054 0.39 11.4 1.2 2 23 919 941 918 941 0.96

14 18 0.12 9 7.1 0.1 1 23 947 969 947 969 0.92

15 18 6 4.3e+02 1.8 0.4 2 23 977 998 977 998 0.92

16 18 0.8 58 4.5 0.5 2 23 1099 1120 1099 1120 0.94

17 18 0.077 5.5 7.8 0.0 1 23 1130 1152 1130 1152 0.96

18 18 7.2e-05 0.0052 17.3 1.0 1 23 1159 1181 1159 1181 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	1.4e-05	0.00098	19.6	3.1	1	23	159	181	159	181	0.98
2	18	0.38	27	5.6	6.2	1	23	187	209	187	209	0.97
3	18	1.8e-07	1.3e-05	25.4	3.2	1	23	215	237	215	237	0.99
4	18	1.4e-05	0.00097	19.6	0.4	1	23	243	265	243	265	0.99
5	18	0.024	1.7	9.3	0.2	2	23	341	365	340	365	0.92
6	18	0.0042	0.3	11.7	0.2	2	23	397	419	396	419	0.95
7	18	0.067	4.8	7.9	0.7	1	23	500	522	500	522	0.97
8	18	0.005	0.36	11.5	0.1	2	23	530	551	529	551	0.91
9	18	0.0028	0.2	12.3	0.1	1	23	559	583	559	583	0.94
10	18	4	2.8e+02	2.4	0.1	2	20	589	607	588	608	0.92
11	18	1.4	1e+02	3.8	0.9	2	23	619	641	618	641	0.95
12	18	0.0028	0.2	12.3	1.1	1	23	702	725	702	725	0.97
13	18	0.0054	0.39	11.4	1.2	2	23	919	941	918	941	0.96
14	18	0.12	9	7.1	0.1	1	23	947	969	947	969	0.92
15	18	6	4.3e+02	1.8	0.4	2	23	977	998	977	998	0.92
16	18	0.8	58	4.5	0.5	2	23	1099	1120	1099	1120	0.94
17	18	0.077	5.5	7.8	0.0	1	23	1130	1152	1130	1152	0.96
18	18	7.2e-05	0.0052	17.3	1.0	1	23	1159	1181	1159	1181	0.97

Sequence Information

Coding Sequence: ATGATGGCCCTAAAAATGCTTTATCGCGGCCCCAGTTCGCGTTTGGAGAATCTAATTGAGAAGATTCAGGCCACCAAGGAGATCACAAATAACGacATGTACAGTACCCACACATCGTCCAGCTACTCGCCGAGCATCTCCGATGGGACCATGACACCCAATGCCCATCATCTGGCGGCCGCCGGCTCGACGAATGCCCTGCAGGAGGATCTCCATCCGGCTGACGGCAAGTCGAACGGTGTCCCCGGAGAGGAGCCTGCCAAGCCAAAGCGACAGCCGCACTttcaccatcaccaccatcacTACCATCACCAGCAGGCGCTGAAGATTGCCAACAAGCTGCGCAAAATCAATAAGGAGGCCAAGATGGCagcggcaggagcagcaggagtcGGAGCTGGCGCCGGCAGTGGAGCAGCCGCAAAGTTTGATAAGTTGACAGGCGAAGGCATTAAGAGTCGCGGCGACGGCTCCTATCAGTGCCAGTTCTGTGATAAGACGTTTCCGCGTCTCGGCTACTTGAAGCATCACGTGCAGAGCCATGCCGAGCATCTGCCCTTCAAGTGCGAGTACTGCGCCAAGCTGTTCAAGCACAAGCGCTCCCGGGATCGCCATAAGAAGCTGCACACCAACGAGCGCAACTACAAGTGTCCGCACTGCGAGGCGGCCTTCTCCCGGAGCGATCACCTGAAGATCCACATGAAGACGCATGACATCCAGAAGCCGTTCCAGTGCAGCATGTGCAACAGGGGCTACAACACGGCCGCGGCCCTCACCTCGCACATGCAGAAGCACAAGAAGAACGCCGCCATACTGGCAGCCGGCGGCAATCCCAATGCCCTCAACTACAGTCCGCGTTCTACGGGCTCCGCCTCGGCGTCGGTGTCCAGCAATGGGAGCCTGCACAAGCGGCGCTatgccctggccctggccaccGACAGCAGCTCCAGTCGCCTGGACTTTCCCAAGAGATCGCGCAGCAGCCATGTGGCCAGTACGCCAACACCCACGCCGCTGCTCCGATGCAGCTACTGCCCCAAGGCGACGGAGTTTAGCAGCTTGGAGCAGCTGAATGCCCATCTTCAGAATGTCcacgaacagcagcaacagcagcagcagcagcagccaccgcagcagcagcagcagtcgtcaAAGACGCCCGTCCAGGAGGGGGAGGGCTTCCAGCTGAGCTGCGAGTATTGCACCATGAAGTTTGGCAACATTGCCGGACTCTTCCAGCACATGCGGGCCACCCATCTGGATCGTCTGAGCAGCCCCAACTCCTACTACGAGCACTTCAATCGGCTGGCCACCGCAGGCACATTCAGTCCGAGGCTGGCGCTGGATCTGCCCAAGATTAAGCCGGATCTGAGCAGTCCCGAGCCGAGGGAGAGCCGACCCGCCGAGGACGACCTGCCCACGGATCTGAGCAGCAACAAGCGTCGAGCGCAGACACCACCCAATCCACCGCCCAATCCCCCGGCACCGCCGGGCATCTTCTTCTGCAATCAGTGCAACGCGGGACTGCCAGACTTCGAGAGCTTTCGCAATCACCTGAAGAGCCACATTGCCGAGGGCATGCAGCTGATCTGTCCCCACTGCGGGCTGAGTCTGCCGGAGCAGTCGGACTTCGAGCGGCACGTGGTGGGCCACTTCCTGATCGCCAACTCCGAGTTCAACTGCAGCGCCAGCTGTGGCAAGAGCTACGGCAAGgcggaggagctgcagcagcatctcaTCAGCGAGCACGTGCTCACCCTGCTGAAGTGCGGCCTCTGCTCGGAGATGTGCGAGACGCGGATGGCCATGCAGCTGCATCTGGCCTGCGCCCACAGCCAGGAGACGAAGCTGCTGCGGTGCAGCGCCTGCATGGAGGTCTTCCGCTCCGATGGCGACTTCCATGTGCACGTGAAGACGCGCCATCAGTTGGGCAaccatcaccagcagcagcagcagcaacagcagcagctccaccaccaacagcaccACCCGATgggcggcaacggcagcagtcCGGCCAATCCGCTGCAGTGCATGTTCTGCCGGGCCGTGTGCTCCTCCGAGCTGGAGATGCACTTCCATCTGGCGGCGCATGCGCGACAATTTCGCTGTCCCTCCTGTCCGGAGACCTTCCACGTCGAGTTCCTGCTCGACAGGCATATGCAGAGCCAGCACGGCGGCGtcaaggagaaggagcagccgCCCCAAAGCTCCCCCAACATGGGCAGTCTCTATGTGAACGCTCTGCTGCCGCCTctggctgcagctgccgcGGCCGCAGccgccaccaacaacaacagcagcatcatcgaCTACAACGTGGCCTTCAAGGGGCTGTTCGGCGGGGGATCGACAGCAGGCAGTGCAGCCACGGGCCCCGCCTCGGCCAGCAAGTTCTACAGCCCCCTGCAGGTGGACACGAACGTCCTGAAGGCGTCACAGAGCTCGCCACATCCCGCCCTGATGTACGGCCTCAGTCAGCGGTATCTGATGGAGATGTACGCCGCCAAGTCCACGTCTCCGGCCAACAGCATCGCCAacgaatcagcagcagcaggaggaggaggtggaggtggaggtggaggggCATCCTCCATCAATGCACCGCCCGCAGCAcaggcgccgccgccgccgccaaacGCACCCGTTGCCACCTTCAGCTGTGGGATGTGCGAGCGCCAGGATCTGCGCAGCGAGGCGGAACTCCACTCGCACCGGAAGCTGGCCCACAACCTGAAGACGGGCGTGAGCCTGCGGTGCGCCTACTGTGCGGGCAACTTCAAGTCGCGGgcggagctggagcagcacaTGAAGAGCTGCCACAACTCGACGGGCAAGCACAAGTGCCTCATCTGCGACGAGATCTTCCCCTCGCCGGCCATCCTCGCGGAGCACAAGCTGCAGCACTCGAAGGTGGGTCAGTCGGGCAAGTGCGCCCACTGCAGCCACCCGCTGGAGGATGTGGCCGCCTTCCGGGCCCATCTCGGCGAGCATGGCAGCGATGGCGCCTCCCTGCCCCTCGCCTGCATTTGCTGTCGCCAGACACTCCACTCGGAGTTCGAGCTGAGCCTCCACGCCAAGTTCCACACCAAGTCCTCGTCCAGTGGCGGCAGCCTCCAGGAACCAGTGTGCGCCCTATGCCTGGAGCCGCTGCCAGGTGCCGTGGATGGACCCACCACCCCGGCCAAGCTGTGCGAGAAGTGCTGCCGCAAGCACAACCTCAACGGCAAGCGGAGCAAGGCCAGCGAGGGAGCCGTGATCCAGGCCCAGACTGGAGCCCCCTACCTGGAGAACCGCTGCAATCTGTGCAAGATGATCCTGCCGCACGCCCAGAAGCTGCAGGAGCACCTGGTGGAGCACACCTTCGCCGGCACCGAGCAGCGCGGCTTCAACTGCTACATCTGCTCGGCCGTCTTCACCGCACCCGGCGGCCTCCTCGGCCACATGGCCGAGCACGGGGCCCACTCGCGTCCCTACGACTGCAACATCTGCCCCGAGAAGTTCTACTTCCGCGCCGAGCTGGAGCACCACCAGCGGGCCCATGAGCTGAGGCCAACGGTTCGTCCAGCGCTGGCCAAGCCAGAGCCACCGATGCGACGCAGTGCATCGCCCAGTCCGAGTCCAGTTCGAAGTCCCACGACCGTCAAGCAGGAGCTGTACGACACGGATACGGCGCACTCGGCGGGCGGAGGGGATGATGAGCCAGAGCACgcccaggaggaggaggagtacatTGAGGTGGAGCAAATTCCGCACGAGACGCGGCCAAGGGATATCATGTCACAGCTGGAAAGGGCCACAAACAGCGCCTGA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEITNNDMYSTHTSSSYSPSISDGTMTPNAHHLAAAGSTNALQEDLHPADGKSNGVPGEEPAKPKRQPHFHHHHHHYHHQQALKIANKLRKINKEAKMAAAGAAGVGAGAGSGAAAKFDKLTGEGIKSRGDGSYQCQFCDKTFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASASVSSNGSLHKRRYALALATDSSSSRLDFPKRSRSSHVASTPTPTPLLRCSYCPKATEFSSLEQLNAHLQNVHEQQQQQQQQQPPQQQQQSSKTPVQEGEGFQLSCEYCTMKFGNIAGLFQHMRATHLDRLSSPNSYYEHFNRLATAGTFSPRLALDLPKIKPDLSSPEPRESRPAEDDLPTDLSSNKRRAQTPPNPPPNPPAPPGIFFCNQCNAGLPDFESFRNHLKSHIAEGMQLICPHCGLSLPEQSDFERHVVGHFLIANSEFNCSASCGKSYGKAEELQQHLISEHVLTLLKCGLCSEMCETRMAMQLHLACAHSQETKLLRCSACMEVFRSDGDFHVHVKTRHQLGNHHQQQQQQQQQLHHQQHHPMGGNGSSPANPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGVKEKEQPPQSSPNMGSLYVNALLPPLAAAAAAAAATNNNSSIIDYNVAFKGLFGGGSTAGSAATGPASASKFYSPLQVDTNVLKASQSSPHPALMYGLSQRYLMEMYAAKSTSPANSIANESAAAGGGGGGGGGGASSINAPPAAQAPPPPPNAPVATFSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCAGNFKSRAELEQHMKSCHNSTGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCSHPLEDVAAFRAHLGEHGSDGASLPLACICCRQTLHSEFELSLHAKFHTKSSSSGGSLQEPVCALCLEPLPGAVDGPTTPAKLCEKCCRKHNLNGKRSKASEGAVIQAQTGAPYLENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPGGLLGHMAEHGAHSRPYDCNICPEKFYFRAELEHHQRAHELRPTVRPALAKPEPPMRRSASPSPSPVRSPTTVKQELYDTDTAHSAGGGDDEPEHAQEEEEYIEVEQIPHETRPRDIMSQLERATNSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00548267;
90% Identity: iTF_00611560;
80% Identity: -