Basic Information

Insect: Drosophila fuyamai
Gene Symbol: L
Assembly: GCA_018153365.1
Location: JAECXW010000758.1:7852475-7868822[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 4.1e-05 0.0032 17.9 3.0 1 23 220 242 220 242 0.98

2 18 0.15 11 6.7 7.3 1 23 248 270 248 270 0.97

3 18 1.6e-07 1.2e-05 25.4 3.2 1 23 276 298 276 298 0.99

4 18 1.2e-05 0.00091 19.6 0.4 1 23 304 326 304 326 0.99

5 18 0.011 0.89 10.2 0.2 2 23 405 429 404 429 0.92

6 18 0.0014 0.11 13.0 0.4 2 23 448 470 447 470 0.96

7 18 0.058 4.5 7.9 0.7 1 23 554 576 554 576 0.97

8 18 0.0033 0.26 11.8 0.1 2 23 584 605 583 605 0.91

9 18 8.8e-05 0.0069 16.8 0.4 1 23 613 637 613 637 0.94

10 18 1.7 1.3e+02 3.3 0.2 2 20 643 661 642 662 0.93

11 18 4.7 3.7e+02 1.9 0.9 2 23 673 695 672 695 0.94

12 18 0.0024 0.19 12.3 1.1 1 23 740 763 740 763 0.97

13 18 0.0047 0.36 11.4 1.2 2 23 940 962 939 962 0.96

14 18 0.038 3 8.5 0.1 1 23 968 990 968 990 0.92

15 18 0.046 3.5 8.3 0.1 2 23 998 1019 997 1019 0.96

16 18 0.7 54 4.5 0.5 2 23 1117 1138 1117 1138 0.94

17 18 0.019 1.5 9.5 0.0 1 23 1148 1170 1148 1170 0.95

18 18 0.00016 0.013 16.0 1.7 1 23 1177 1199 1177 1199 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	4.1e-05	0.0032	17.9	3.0	1	23	220	242	220	242	0.98
2	18	0.15	11	6.7	7.3	1	23	248	270	248	270	0.97
3	18	1.6e-07	1.2e-05	25.4	3.2	1	23	276	298	276	298	0.99
4	18	1.2e-05	0.00091	19.6	0.4	1	23	304	326	304	326	0.99
5	18	0.011	0.89	10.2	0.2	2	23	405	429	404	429	0.92
6	18	0.0014	0.11	13.0	0.4	2	23	448	470	447	470	0.96
7	18	0.058	4.5	7.9	0.7	1	23	554	576	554	576	0.97
8	18	0.0033	0.26	11.8	0.1	2	23	584	605	583	605	0.91
9	18	8.8e-05	0.0069	16.8	0.4	1	23	613	637	613	637	0.94
10	18	1.7	1.3e+02	3.3	0.2	2	20	643	661	642	662	0.93
11	18	4.7	3.7e+02	1.9	0.9	2	23	673	695	672	695	0.94
12	18	0.0024	0.19	12.3	1.1	1	23	740	763	740	763	0.97
13	18	0.0047	0.36	11.4	1.2	2	23	940	962	939	962	0.96
14	18	0.038	3	8.5	0.1	1	23	968	990	968	990	0.92
15	18	0.046	3.5	8.3	0.1	2	23	998	1019	997	1019	0.96
16	18	0.7	54	4.5	0.5	2	23	1117	1138	1117	1138	0.94
17	18	0.019	1.5	9.5	0.0	1	23	1148	1170	1148	1170	0.95
18	18	0.00016	0.013	16.0	1.7	1	23	1177	1199	1177	1199	0.98

Sequence Information

Coding Sequence: ATGCGCAGTTTGGGGGCACTGCTCTTTCCTGCTCTTAAGTTGGGTGACTGCGGGATTTGGATGGGGGAAGTGGTACTTTGGGAGCTTACTTGCTGGGGAAAGGGCATCCTGCCGCCGCTGCCCTTTGGCCCCAAGTTATTCCATCCAAGACGTCGAGGCCACGACGATGGGGAAGCAGAGGAACCGGATGAGCCGGAGGACCTGGATTTGGACGAGGAGCTACTCAGTCTCAGCGGGGACGAGGACTACGACGACGAGGAGCTGCAGAGCCTGGACAGCTTCTACTCAGATATGTACAGTACCCACACATCCTCCAGTTATTCGCCTAGTATTTCTGATGGCACCATGACACCTAATTCACACCATTTGCCCGGAGCTCCAACCGCCGCTGGTGGTCAAGAGGATCATCCGGCTGAGGGCAAGGCCAATGGTGGCGCCGATGGCGAGGAGTTGCCCAAGCCAAAACGTTTGCCCCACTTCCATCACCATCACCACCATCACTACCACCATCAACAGGCGCTGAAAATAGCCAACAAGTTGCGCAAAATCAATAAGGAAGCCAAAATGGGAGCTACTGCGGGTGCGGGATCCACTGGAGCAGCCGCAAAGTTTGATAAGTTGACAGGAGAGGGGATTAAAAGTCGCGGCGACGGCTCCTATCAGTGTCAGTTCTGCGAAAAGACATTTCCACGTCTCGGCTACTTGAAGCATCACGTACAGAGCCACGCTGAACACCTGCCTTTCAAATGTGAGTACTGCTCCAAGCTTTTCAAGCACAAGCGTTCCCGTGATCGTCATAAGAAATTGCATACCAACGAGCGGAATTACAAGTGTCCACATTGCGAGGCCGCTTTTTCGAGGAGTGACCATTTGAAGATCCATATGAAAACCCACGACATCCAGAAGCCCTTCCAGTGTAGTATGTGTAACAGGGGCTATAATACAGCTGCCGCTCTTACGTCTCACATGCAAAAGCACAAGAAGAACGCAGCTATCCTGGCAGCCGGTGGTAATCCCAATGCCCTTAACTATAGTCCTCGATCGACGGGATCTGCCTCGGCATCGGTTTCCAGCAATGGTAGTCTGCAGAAGCGGAGATATGCCTTGGCCCTGGCTTCAGATAGTAGTCCCAGTAGATTGGATTTCCCCAAGAGATCGAGAAGTAGTCATGTGGGTGGCACTACCACCACTGCCACGCCCACTCCCCTGCTGAGGTGCAGCTACTGCCCCAAGGTCACAGAGTTCAGTAGTCTGGAGCAGTTGAATGCCCATCTCCAGAGTGTTCATGAGCAACAGCAGGCTGTGAAGACGCCGGTTCAGGAAAGCGAAGGCTTTCAGCTGAGCTGTGAGTACTGCACCATGAAGTTTGGCAATATCGCCGGACTCTTCCAGCACATGAGAAGCACCCACATGGACAGGCTGAGCAGCCCGAACTCCTACTACGAGCACTTCAATCGTTTGGCCACCGCCGGTACATTCAGTCCACGTCTTGCCCTGGATATGCCCAAAATTAAACCGGATTTGGGAAGTCCGGAGAGGGAATCGCGGCCTGTAGAGGACGATCTTCCCACGGATTTGAGCAGCAACAAGAGGAGACCGATGACACCCAACCCTCAAACACACACTCAACTGGCACCACCGGCTGGTCCACCAGGGGTGTTCTTCTGCAATCAGTGCAACGCTGGGCTACCGGATTTCGAGAGCTTCAGGAATCATCTGAAGAGTCACATTGCCGAGGGCATGCAGTTGGTTTGTCCTCATTGCGGGCTGAGTTTGCCAGAGCAATCGGAGTTCGAGCGTCATGTGGTGGGTCACTTCCTCATCACTGGCTCGGAGTTCAACTGTAGTTCCAGCTGCGGAAAGAGTTTTGCCAAATCGGAGGATCTGCAGCAACATTTACTTTCAGAGCACGTGCTAACCCTTTTGAAGTGTTCCTTGTGTTCGGAGGTTTGTGAGAGTCGAATGGCCATGCAGCTCCATTTGGCCTGTGCGCACAGTCAGGAAACGAAACTCCTCCGCTGCAGCGCTTGTTTGGAGCTCTTCCGATCCGATGCCGAGTTCCATGTGCATGTCAAGACACGTCACCAGTTGGGCGGACACCCCACGTTGGGCGCCAATTCCAGTGCCCCCACTAATCCACTGCAGTGTATGTTTTGCCGGGCAGTTTGCTCCTCCGAGTTGGAGATGCACTTCCACTTGGCCGCCCACGCCCGTCAGTTTAGATGTCCCTCTTGCCCGGAGACCTTCCACGTGGAGTTCCTGCTGGATCGTCACATGCAGAGTCAGCATGGCGGAGTCAAGGACAAAGAGGCGAACTCGCCCAACATGGGTAGTCTCTATNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGGGCTTATTCGGAGGAGCGGCTGGGGGAGCAGGAGCTCAAGCACCCGGTGGAGCACCCCCCTCAAGTAACAAGTTCTACAGCCCCCTACAAGTGGACACCAATGCATTGAAGCCACAAACCTCCCCCCACCCGGCTCTAATGTATGGTCTGAGTCAACGATATCTGATGGAGATGTATGCCGCCAAGTCCACATCGCCCTCGGGAAATGAGGGTGTTGGAAATCCACAACCGGCGGCTCCTCAGGCCACCGCACCACCACCATCAAATGCAAACACTGCCACCTTTAGTTGCGGAATGTGCGAGCGACAGGATTTGCGCAGCGAGGCGGAGCTCCACTCCCATCGCAAACTGGCCCACAATCTGAAGACGGGAGTGAGTTTGCGATGTGCCTACTGTGCGGGAAATTTCAAATCTCGAGCCGAACTGGAGCAGCACATGAAGAGCTGTCACAATTCGACGGGCAAGCACAAGTGTTTGATATGCGACGAGGTATTCCCCTCACCGGCCATCCTGGCCGAGCATAAGTTGCAGCACTCGAAGGTGGGGCAGTCTGGTAAGTGCTCCCACTGTGGTCAACCTCTGGAGGATGTGGCTGCCTTCAGGGCTCATCTATCCGAACATGGAAGCGATGGAGCCTCCTTGCCACTAGCCTGCATTTGCTGCCGCCAAACGTTGCACTCGGAATTCGAGCTAAGTCTGCATGCCAAATTCCACACCAAGTCCTCCACGAGCGGTGGAAGTCTACAGGAACCAGTGTGTGCTCTGTGCCTGGAACCTCTACCCGATGCCGTCGAGGGTCCAGCGAAGCTCTGCGACAAGTGCTGCCGTAAGCATAACTTGAATGGAAAACGGGGCAAGCACAGTGAGGCACCCACATCTCTGCCAGCACCGCCCTCGGCATTCGTGGAGAATCGCTGCAACCTGTGCAAGATGATCCTGCCACATGCCCAGAAACTGCAGGAACATCTGGTGGAACACACCTTCGCGGGCACCGAACAGCGTGGCTTCAATTGCTACATATGCTCGGCCGTCTTCACCGCACCCGGTGGTCTGCTCAACCACATGGGTGAGCATGGAGCTCATTCGCGACCCTACGATTGCAGTCTCTGCCCCGAGAAATTCTACTTCCGGGCCGAGTTGGAACACCACCAAAGGAGCCATGAGTTGAGACCACAGGGACGTCAGCCAGTATCAAAAGTGGAGGTGCCTTCCAACCGGAACAATTCGCCCACCCAGAGTCCGGAGCGAAGTCCCACGATTGTCAAACAGGAGCTATACGAAACGGATACTGTTGAATCCGCTGGAGGAGAAGAGGAGCCGGAGAATCAACCAGACGAAGAGGAGTACATCGAAGTCGAGCAAATGCCACATGAGACACGTCCAAGTGAGATTGGGTCGCAAATGGAAAGGTCCACCAGTAGCGCCTAA
Protein Sequence: MRSLGALLFPALKLGDCGIWMGEVVLWELTCWGKGILPPLPFGPKLFHPRRRGHDDGEAEEPDEPEDLDLDEELLSLSGDEDYDDEELQSLDSFYSDMYSTHTSSSYSPSISDGTMTPNSHHLPGAPTAAGGQEDHPAEGKANGGADGEELPKPKRLPHFHHHHHHHYHHQQALKIANKLRKINKEAKMGATAGAGSTGAAAKFDKLTGEGIKSRGDGSYQCQFCEKTFPRLGYLKHHVQSHAEHLPFKCEYCSKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASASVSSNGSLQKRRYALALASDSSPSRLDFPKRSRSSHVGGTTTTATPTPLLRCSYCPKVTEFSSLEQLNAHLQSVHEQQQAVKTPVQESEGFQLSCEYCTMKFGNIAGLFQHMRSTHMDRLSSPNSYYEHFNRLATAGTFSPRLALDMPKIKPDLGSPERESRPVEDDLPTDLSSNKRRPMTPNPQTHTQLAPPAGPPGVFFCNQCNAGLPDFESFRNHLKSHIAEGMQLVCPHCGLSLPEQSEFERHVVGHFLITGSEFNCSSSCGKSFAKSEDLQQHLLSEHVLTLLKCSLCSEVCESRMAMQLHLACAHSQETKLLRCSACLELFRSDAEFHVHVKTRHQLGGHPTLGANSSAPTNPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGVKDKEANSPNMGSLYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGLFGGAAGGAGAQAPGGAPPSSNKFYSPLQVDTNALKPQTSPHPALMYGLSQRYLMEMYAAKSTSPSGNEGVGNPQPAAPQATAPPPSNANTATFSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCAGNFKSRAELEQHMKSCHNSTGKHKCLICDEVFPSPAILAEHKLQHSKVGQSGKCSHCGQPLEDVAAFRAHLSEHGSDGASLPLACICCRQTLHSEFELSLHAKFHTKSSTSGGSLQEPVCALCLEPLPDAVEGPAKLCDKCCRKHNLNGKRGKHSEAPTSLPAPPSAFVENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPGGLLNHMGEHGAHSRPYDCSLCPEKFYFRAELEHHQRSHELRPQGRQPVSKVEVPSNRNNSPTQSPERSPTIVKQELYETDTVESAGGEEEPENQPDEEEYIEVEQMPHETRPSEIGSQMERSTSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00548267;
90% Identity: iTF_00504840;
80% Identity: -