Basic Information

Insect: Drosophila paramelanica
Gene Symbol: -
Assembly: GCA_035043915.1
Location: JAWNMO010000018.1:2931479-2934629[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 3.4e-05 0.0021 18.3 4.7 1 23 170 193 170 193 0.97

2 16 0.0013 0.082 13.3 3.1 1 23 240 263 240 263 0.96

3 16 0.001 0.064 13.6 2.4 1 23 330 353 330 353 0.93

4 16 0.007 0.43 11.0 0.4 2 23 405 426 404 426 0.96

5 16 9.5 5.9e+02 1.2 1.1 1 19 539 557 539 560 0.72

6 16 0.011 0.7 10.4 0.5 1 23 569 591 569 591 0.96

7 16 0.00029 0.018 15.4 2.1 1 23 598 620 598 621 0.95

8 16 0.00046 0.029 14.7 1.4 2 23 629 650 628 650 0.96

9 16 0.0019 0.12 12.8 0.1 3 22 678 697 676 700 0.89

10 16 0.02 1.2 9.6 1.0 1 23 736 759 736 759 0.96

11 16 0.23 14 6.3 2.1 1 22 766 787 766 787 0.97

12 16 0.0012 0.072 13.5 1.0 1 23 796 819 796 819 0.97

13 16 1.7e-05 0.001 19.3 0.5 1 23 838 861 838 861 0.97

14 16 0.039 2.4 8.7 0.2 1 23 871 893 871 893 0.94

15 16 2.5e-05 0.0016 18.7 3.3 1 23 899 921 899 921 0.99

16 16 5.3e-05 0.0033 17.7 0.9 1 23 927 949 927 949 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	3.4e-05	0.0021	18.3	4.7	1	23	170	193	170	193	0.97
2	16	0.0013	0.082	13.3	3.1	1	23	240	263	240	263	0.96
3	16	0.001	0.064	13.6	2.4	1	23	330	353	330	353	0.93
4	16	0.007	0.43	11.0	0.4	2	23	405	426	404	426	0.96
5	16	9.5	5.9e+02	1.2	1.1	1	19	539	557	539	560	0.72
6	16	0.011	0.7	10.4	0.5	1	23	569	591	569	591	0.96
7	16	0.00029	0.018	15.4	2.1	1	23	598	620	598	621	0.95
8	16	0.00046	0.029	14.7	1.4	2	23	629	650	628	650	0.96
9	16	0.0019	0.12	12.8	0.1	3	22	678	697	676	700	0.89
10	16	0.02	1.2	9.6	1.0	1	23	736	759	736	759	0.96
11	16	0.23	14	6.3	2.1	1	22	766	787	766	787	0.97
12	16	0.0012	0.072	13.5	1.0	1	23	796	819	796	819	0.97
13	16	1.7e-05	0.001	19.3	0.5	1	23	838	861	838	861	0.97
14	16	0.039	2.4	8.7	0.2	1	23	871	893	871	893	0.94
15	16	2.5e-05	0.0016	18.7	3.3	1	23	899	921	899	921	0.99
16	16	5.3e-05	0.0033	17.7	0.9	1	23	927	949	927	949	0.98

Sequence Information

Coding Sequence: ATGACTAGAACGTGCCGAATCTGCGGCGGCGCAGACGGACGCTTCTGGATCGAGACGCCAGTCAATAAATACGCGGAGAAAACATACAATCAATTACTGCTGGAGCTGACCAAGCTGCAGGTCGCCTTGGATCAAGCTGACAAATTGCCGCCCTGGATTTGTCGAAGCTGCGCCCAGAGATTAGAGCATGCATATGACTTTGTGCTGCAGGCGCGCGAAACACACGAGCTATGGCTGCAAAAGCTAGCAAAAGCATCCTCGTCGGAGGACCAGGAAACAGGCACTTTAGAGTGTTTGCGAGAGACGCCAATACAATTGCTGGAAATAGAAGGCGTCACAATTAAAATGGAAGAGCCCTCAGAGCCGGTCATGGCCTCAACGGATCAAGGCAATCCAATTGATCCCCTAATCAAGAAAAGCATTGTGAATGATGAcagcgatgacgatgatgatgatgatgtacCGCTTAAGCAGCGTCAGAAAGCAAACTGCAAGCTACCAACGTTGCACAAGTGCAATAAATGTGGAAAAGCCTTCAAATATGTCACCAATCTGTTCAGGCACAAGCAGCGGGATCACAGCCCGACGAAGGTACATGAAACGGAGGAGAACTCAAAGACTGATCGCGCGGAACCATTTCTGCACAACCTTATAAGGAGCTCAATGGCAACACGAGGCAGCACGACAGAAGTGGACAACGACTCAACGGATGGTTACTACAAGTGCGATCAATGCGACAAATCCTACAAGTACATAATGCTGCTCATCAAGCACAAGCACAAGGCGCATGTGTCCAGCCAGTTGCCAGCGCAGCCCAAGCCCATAGGCAAAAGCAATTCTAGCACGGAGCCAACTGCGGCCAAAACAAGAGGATCCCAGCGTCAACGCTCGAAGGCACCGAGCACCGATTCCCTGGTGCACAGCATCATCAAAGAGATTAACCTACCCGATGAGGACGATGCAGGCAACTCGAGTGCTGACAATTACTACAAATGCGATCAGTGCGACAAATCCTACAAGTACATCGTCAGTCTTATCAAGCACAACCACAGTGAGCACAAAGCGTACAAAGACTCTgatgaggacgacgacgaagcCACCTCCTCGAGATATGCAGCGGATGCAAGTGCCATGTCGAAACCCTCGCGCATCGATCGACGCGTCAAGGGCTTCGATTTGCATCGGTGCAAACCGAATGGCTCCAAGGAAATCCAATGCATGATTTGTCTGCGCAGATTTGTCAAACTGCGCGAGCTGCGAGACCATTTAAAGGCGCATCCCAAAGACTTTACCTTCGAGGCGCACGGCGAGCCGATTGAGCGCATTGCCGAAGGCTTCTACAAGACCGCCGTGGAATCCACAGACGCTGGCCTCAAGCGGCGCATTTTCAATGATCTCAATGTGGGCATGTTTGGCCGCTATTACTCCATTACCAATGAGGCTCGCTACGAGATGAATCTGGACAGCTCAGACACGGACAGTGACGGCGAAGGGGATGTTGTAGAGCGACATAGCTACGCCTGCGAGTTGTGCGATTCCTCCGATGCCGTCTGGCCGCGCAAATATCAACTGCACGAACATCATCGATTGCAGCACACCTGGCTGGAGGCGCCGCATGTCTGCCAGCGATGTGATTCACGTTTCCTAAGCGCGCAGCTGCTGGATCATCACACGCTCAAGCTATGCCAGAACACGCTCAAGCGTTTCATGTGCGACAAGTGTCCACAGCGGTTTTTCTGGCGACGCAATCTGCGCGCGCATCTAGCGGAGCACAAGAACAAGCAAGAGACCTATCCGTGTGATCAGTGCTCGCGCAGCTTTCAGGATAAGAGTGCCGTAACCAAGCATAAGCTAATGCATCACGATGGCAGCAATGAGCTTCTGCCCTGCCGCTGGTGCACGCGCACCTTCTATCGGCCCGCGCTGCTGCACAAACATGTGCAACGGCATGGCTTCAGCGGCGAGGATTTGCCCCTGGCCGAGACACTGCTGGCGGATGCCGCTAAGACATCCGGACCAAAGACAATCATTTGCAAGCTGTGCGACATGCAGTTTATTACCATTGCCGATCTGCGACGACACATCTCGATGCAGGGCCACGGCGAACAGGCGGCCAACTATATGATTAGCACCGAGGAGGgctttgagctgctgctggatgaTACGGACGAGAGCGACGATGATGCTGCCGGCACTGCCACATCCTATCGGTGTGCGCTGTGCGATATGAATTTCCAGCGACGCCGCGAAATGAGCGAACATCAGTATTCACTGCACACATTCGACAAGCTGCCGTATTCCTGTGAGCATTGCATTTTCAAGACAGTCGACAAGACCATGCTGGAGCATCACCAGCGTACGCAGTGCCTCAACCAGGAGAAGAAATTCAAGTGCTCTCGCTGTGGCTATAAATTCATGTGGCGTGAAAATCTCGAACAGCACATGATCAGCCAGCACCCCAAGTCCTCCAATCAAGCGCCGGTGGCAATTAAGCGAAGCAGACGCTTCAGATATCAGTGTCCGCACTGCTGGCGCTCGTTTGTCGTGCAGCCCAGCCTGGACAAGCACATACGCGATATGCATGTGGCCAAAAAGAATCCCGGCAAAAAATATCTCTGCTCACTGTGCGGCCTGGAATCGCTGACGCCCAACAAGCTCAACATCCACATGCGCCGTCACAACGGCGAGAAGCCCTTCAAGTGCGATCTCTGCGACATGTCCTTTACCGTGCACTACGAGCTCAAGGTGCATCGGCGCAAGCACACTGGCGAGCGACCCTATCAGTGCACGTTCTGTGCCAAGGATTTCGCCAGGCCCGATAAGCTGAGGCGGCATGTTTACATGCACAGCGTTAAACGCTAg
Protein Sequence: MTRTCRICGGADGRFWIETPVNKYAEKTYNQLLLELTKLQVALDQADKLPPWICRSCAQRLEHAYDFVLQARETHELWLQKLAKASSSEDQETGTLECLRETPIQLLEIEGVTIKMEEPSEPVMASTDQGNPIDPLIKKSIVNDDSDDDDDDDVPLKQRQKANCKLPTLHKCNKCGKAFKYVTNLFRHKQRDHSPTKVHETEENSKTDRAEPFLHNLIRSSMATRGSTTEVDNDSTDGYYKCDQCDKSYKYIMLLIKHKHKAHVSSQLPAQPKPIGKSNSSTEPTAAKTRGSQRQRSKAPSTDSLVHSIIKEINLPDEDDAGNSSADNYYKCDQCDKSYKYIVSLIKHNHSEHKAYKDSDEDDDEATSSRYAADASAMSKPSRIDRRVKGFDLHRCKPNGSKEIQCMICLRRFVKLRELRDHLKAHPKDFTFEAHGEPIERIAEGFYKTAVESTDAGLKRRIFNDLNVGMFGRYYSITNEARYEMNLDSSDTDSDGEGDVVERHSYACELCDSSDAVWPRKYQLHEHHRLQHTWLEAPHVCQRCDSRFLSAQLLDHHTLKLCQNTLKRFMCDKCPQRFFWRRNLRAHLAEHKNKQETYPCDQCSRSFQDKSAVTKHKLMHHDGSNELLPCRWCTRTFYRPALLHKHVQRHGFSGEDLPLAETLLADAAKTSGPKTIICKLCDMQFITIADLRRHISMQGHGEQAANYMISTEEGFELLLDDTDESDDDAAGTATSYRCALCDMNFQRRREMSEHQYSLHTFDKLPYSCEHCIFKTVDKTMLEHHQRTQCLNQEKKFKCSRCGYKFMWRENLEQHMISQHPKSSNQAPVAIKRSRRFRYQCPHCWRSFVVQPSLDKHIRDMHVAKKNPGKKYLCSLCGLESLTPNKLNIHMRRHNGEKPFKCDLCDMSFTVHYELKVHRRKHTGERPYQCTFCAKDFARPDKLRRHVYMHSVKR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00541936; iTF_00547508; iTF_00482435; iTF_00496805; iTF_00528230; iTF_00597575; iTF_00521577; iTF_00593294; iTF_00497584; iTF_00558928; iTF_00610097; iTF_00560469; iTF_00560470; iTF_00574238; iTF_00511459; iTF_00499045; iTF_00500486; iTF_00543919; iTF_00535505; iTF_00561188; iTF_00566981; iTF_00552486; iTF_00496018; iTF_00530451; iTF_00598331; iTF_00589006; iTF_00508540; iTF_00495300; iTF_00516420; iTF_00540521; iTF_00476779; iTF_00532532; iTF_00544644; iTF_00582402; iTF_01324324; iTF_01323555; iTF_01322829; iTF_01325091; iTF_01326600; iTF_01321355; iTF_01327331; iTF_01328064; iTF_01320625; iTF_00805382; iTF_00803791; iTF_00520071; iTF_00502678; iTF_00559641; iTF_00572741; iTF_00509965; iTF_00568404; iTF_00586827; iTF_00534730; iTF_00506267; iTF_00526749; iTF_00617053; iTF_00563326; iTF_00475365; iTF_00549002; iTF_00525338; iTF_00576513; iTF_00587563; iTF_00522383; iTF_00570569; iTF_00517154; iTF_00616369; iTF_00486035; iTF_00518614; iTF_00501977; iTF_00553210; iTF_00564831; iTF_00599039; iTF_00583136; iTF_00498320; iTF_00596132; iTF_00513610; iTF_00577232; iTF_00557362; iTF_00499758; iTF_00542609; iTF_00607250; iTF_00620033; iTF_00538387; iTF_00546803; iTF_00599740; iTF_00512884; iTF_00545396; iTF_00551028; iTF_00531109; iTF_00490930; iTF_01325813; iTF_00493816; iTF_00473214; iTF_00479626; iTF_00551739; iTF_00554527; iTF_00549696; iTF_00573472;
90% Identity: iTF_00547508;
80% Identity: -