Basic Information

Insect: Drosophila murphyi
Gene Symbol: -
Assembly: GCA_018904325.1
Location: JAEIFX010001229.1:7105676-7109232[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 3.1e-05 0.0022 18.2 5.3 1 23 174 197 174 197 0.97

2 16 0.0017 0.12 12.8 3.9 1 23 249 272 249 272 0.96

3 16 0.00076 0.053 13.9 2.8 1 23 338 361 338 361 0.94

4 16 0.0076 0.53 10.7 0.4 2 23 413 434 412 434 0.96

5 16 3.2 2.2e+02 2.5 3.0 1 20 547 566 547 568 0.85

6 16 0.018 1.2 9.6 0.6 1 23 577 599 577 599 0.94

7 16 0.00026 0.018 15.4 2.1 1 23 606 628 606 629 0.95

8 16 0.00041 0.028 14.7 1.4 2 23 637 658 636 658 0.96

9 16 0.013 0.87 10.0 0.1 2 21 685 704 684 708 0.88

10 16 0.1 7.2 7.2 0.9 1 23 746 769 746 769 0.95

11 16 1.3 92 3.7 2.2 1 22 776 797 776 797 0.93

12 16 0.00052 0.036 14.4 1.2 1 23 806 829 806 829 0.98

13 16 1.5e-05 0.001 19.3 0.5 1 23 850 873 850 873 0.97

14 16 0.089 6.1 7.4 0.2 1 23 883 905 883 905 0.94

15 16 2.2e-05 0.0015 18.7 3.3 1 23 911 933 911 933 0.99

16 16 4.7e-05 0.0033 17.7 0.9 1 23 939 961 939 961 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	3.1e-05	0.0022	18.2	5.3	1	23	174	197	174	197	0.97
2	16	0.0017	0.12	12.8	3.9	1	23	249	272	249	272	0.96
3	16	0.00076	0.053	13.9	2.8	1	23	338	361	338	361	0.94
4	16	0.0076	0.53	10.7	0.4	2	23	413	434	412	434	0.96
5	16	3.2	2.2e+02	2.5	3.0	1	20	547	566	547	568	0.85
6	16	0.018	1.2	9.6	0.6	1	23	577	599	577	599	0.94
7	16	0.00026	0.018	15.4	2.1	1	23	606	628	606	629	0.95
8	16	0.00041	0.028	14.7	1.4	2	23	637	658	636	658	0.96
9	16	0.013	0.87	10.0	0.1	2	21	685	704	684	708	0.88
10	16	0.1	7.2	7.2	0.9	1	23	746	769	746	769	0.95
11	16	1.3	92	3.7	2.2	1	22	776	797	776	797	0.93
12	16	0.00052	0.036	14.4	1.2	1	23	806	829	806	829	0.98
13	16	1.5e-05	0.001	19.3	0.5	1	23	850	873	850	873	0.97
14	16	0.089	6.1	7.4	0.2	1	23	883	905	883	905	0.94
15	16	2.2e-05	0.0015	18.7	3.3	1	23	911	933	911	933	0.99
16	16	4.7e-05	0.0033	17.7	0.9	1	23	939	961	939	961	0.98

Sequence Information

Coding Sequence: ATGACAAGAACGTGTAGAATCTGCGGTGGCGCAGATGGACGCTTCTGGATCGAGACGCCAATTGATAAATATGCGGAGAAAACATTCAATCACCTGCTGCTGGAGCTAACAAAACTCGAGGTCACTGTGGATCAAGCTGATAAGCTACCGCCATGGATCTGCCGCAACTGTGCGCACAGATTAGAAAATGCCTACGACTTTGTGCTGCAGGCGAGGGAAACTCACGAGCTTTGGCTGCACAAGATGACAACAGAATCTCTATCGGAGGACACCGAAACTGGGACGTTGGAGTGCCTGCGAGAGACACCCATTCAATTGCTGGAGATTGAGGGCGTCACAATTAAAATGGAAGAGGCAACTGGACCAGCCGTGCCACAAACAGATTCAGTCGGCTCGATTGATCCGCTAATTAAAAAGAGCCGAGAGGATGATGCCAGCAATAATGATGATGACGCAGATGATGATGATGATATTCCGCTCAAGCAGCGCCGGATTGCAAGCACAAAACTGCCAACGATGCACAAGTGCAATAAGTGCGACAAGGCCTTCAAATATGTAACGAATCTCTTCAGGCACAAGCGACGAGATCACTCTCCAGAGCACAGCCATACCAAAGAACAGGCAGCAGTGGAAAGTGAAAAGACTGATGGCATGAAACCGCTCTTAAACGATGTAATCAAGAGCTCTATTGCAACAACACACAGCAGCGAGGCAGACTTGGAAAGCGAATTGGCGGATAGTTACTACAAGTGCGATCAATGCGACAAATCCTACAAGTACATAATGCTGCTGATCAGACACAAGCACAAGACGCACGCTTCCAGCCAGTGTCCAGCACAGCCCAGACCAATTAGAAGAAACGGTTCGAGTGCAGAGCAAACTAATACTAAACAAGGTTCACCGCCTCAGCACTCGAAACCGACCAACACAGATTCGCTTGTGCACAGCATCATCAAAGAGATCAACTTACCCGATGAAGACGATGCAGACAGTTCCAGTGCCGACAATTACTACAAGTGCGACCAGTGTGACAAGTCGTACAAATACATTGTGAGTCTCATCAAGCACAAACACAACGAGCACAAGGAATACAGGGATTCCGATGAGGATGAAGATGGGGCAACGTCCTCCAGATATGCAGCAGATGCCACTGTTATGTCGAAGCCGTCGCGCATTGATCGTCGCGTCAAAGGCTTCGATTTGAATCGCTGCCGCCCAAACGGTTCCAAAGAGATTCAGTGCATGATCTGTCTGCGCAGATTCATCAAGTTGCGCGAGCTGCGTGATCACCTGAAAGCCCATCCTAAAGACTTCACATTCGATGCTCATGGCGAGCCGATTGAGCGCATTGCCGAGGGGTTCTATAAGACAGCCGTGGAATCCACAGTTGCGGGCCTCAAGCGACGGATCTTCAACGATCTCAAGGTTGGCATGCTCGGACGCTACTATTCCATAACAAATGAGGCACGGTACGAGATGAATCTGGACAGCTCGGACACGGACAGCGACGGCGAAGCGGATGTTGTGCAGCGGCATTCGTATGCCTGCGAATTGTGCGACTCCGCCGATGCCGTCTGGCCACGCAAATATCAATTGCACGAGCATCATCGGCAGCAGCACACCTGGCTGGAAGCGCCGCACGTCTGCCAGCGCTGTGACTTCCGCTTCCTGAGCGCGCAGCTGCTCGAGCATCATACGCACAAGTTGTGCCAGAACACCCTGAAGCGCTTCATGTGCGACAAGTGTCCACAGCGCTTCTTTTGGCGACGCAATCTACGTGCGCATCTTGTCGAGCACAAAAACAAGCAGGAGACGTATCCGTGTGATCAGTGCTCGCGCAGCTTTCAGGACAAGAGCGCCGTGACGAAGCACAAGCTGATGCACCACGATGTACACAACGAGCTGTTGCCCTGTCGCTGGTGCACGCGCACCTTCTACCGGCCGGCGCTGTTGCACAAGCATGTGCAGCGTCACGGCTTTAGTGGGGAGGATCTGCCGCTGGCAGAGACACTGCTGGCGGATGCCGCCAAGCCATCTGGTACGAAGACGATTGTCTGCAAACTTTGCGATATGCAGTTCATTAGCATTGGCGACCTGCGGCGACACAACTCGATGCAGGCGCACAGTGAGCAGGTGTCCAACTATATGATAAGCACCGAGGAGGGATTCGAGCTGCAGCTGGATGAAACGGACGAGAGTGATGAGGAGCCCACAAGTACTGCTGCCAGCCGATCTTATCGATGCGATCTGTGCGAGATGAGTTTCCTGCGAAGGCGCGACATGAGCGAACATCAATATTCGCTGCACACCTTCGACAAGCTGCCACATTCTTGTGAGCATTGCATTTACAAGACAGTCGATAAGACCATGCTAGAGCACCATCTGAGCACACAGTGTCTTAACGAGGAGAAGAAATTCAAGTGCTCTCGTTGCGGCTACAAATTCATGTGGCGCGAAAATCTGGAGCAGCACATGAGCACTCTGCATCCAAAGTCATCATCTAGTCAGACGCCCGTTGCGGCGACAAAGCGGAGTAGACGTTTCCGATACCAGTGTCCACACTGCTGGCGCTCGTTTGTGGTGCAGCCCAGCCTGGACAAGCACATTCGGGACATGCATGTGGCGAAAAAGAATCCCGGCAAGAAGTATCTATGCTCGTTGTGCGGCCTGGAGTCGCTGACCCCAAATAAGCTCAGCATACACATGCGGCGTCACAACGGCGAGAAGCCATTCAAATGTGATCTCTGCGACATGTCCTTCACCGTGCACTACGAGCTGAAGGTTCATCGCCGCAAGCATACCGGCGAGCGACCCTATCAATGCACATTCTGTGCCAAGGATTTTGCCCGGCCGGATAAGCTAAGACGGCATGTTTACATGCATAGCGTTAAGCGTTAA
Protein Sequence: MTRTCRICGGADGRFWIETPIDKYAEKTFNHLLLELTKLEVTVDQADKLPPWICRNCAHRLENAYDFVLQARETHELWLHKMTTESLSEDTETGTLECLRETPIQLLEIEGVTIKMEEATGPAVPQTDSVGSIDPLIKKSREDDASNNDDDADDDDDIPLKQRRIASTKLPTMHKCNKCDKAFKYVTNLFRHKRRDHSPEHSHTKEQAAVESEKTDGMKPLLNDVIKSSIATTHSSEADLESELADSYYKCDQCDKSYKYIMLLIRHKHKTHASSQCPAQPRPIRRNGSSAEQTNTKQGSPPQHSKPTNTDSLVHSIIKEINLPDEDDADSSSADNYYKCDQCDKSYKYIVSLIKHKHNEHKEYRDSDEDEDGATSSRYAADATVMSKPSRIDRRVKGFDLNRCRPNGSKEIQCMICLRRFIKLRELRDHLKAHPKDFTFDAHGEPIERIAEGFYKTAVESTVAGLKRRIFNDLKVGMLGRYYSITNEARYEMNLDSSDTDSDGEADVVQRHSYACELCDSADAVWPRKYQLHEHHRQQHTWLEAPHVCQRCDFRFLSAQLLEHHTHKLCQNTLKRFMCDKCPQRFFWRRNLRAHLVEHKNKQETYPCDQCSRSFQDKSAVTKHKLMHHDVHNELLPCRWCTRTFYRPALLHKHVQRHGFSGEDLPLAETLLADAAKPSGTKTIVCKLCDMQFISIGDLRRHNSMQAHSEQVSNYMISTEEGFELQLDETDESDEEPTSTAASRSYRCDLCEMSFLRRRDMSEHQYSLHTFDKLPHSCEHCIYKTVDKTMLEHHLSTQCLNEEKKFKCSRCGYKFMWRENLEQHMSTLHPKSSSSQTPVAATKRSRRFRYQCPHCWRSFVVQPSLDKHIRDMHVAKKNPGKKYLCSLCGLESLTPNKLSIHMRRHNGEKPFKCDLCDMSFTVHYELKVHRRKHTGERPYQCTFCAKDFARPDKLRRHVYMHSVKR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00567692;
90% Identity: iTF_00570569;
80% Identity: -