Basic Information

Insect: Drosophila cyrtoloma
Gene Symbol: -
Assembly: GCA_035042485.1
Location: JAWNLH010000666.1:53163-56733[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 3.5e-05 0.0023 18.2 5.3 1 23 175 198 175 198 0.97

2 16 0.0018 0.12 12.8 3.9 1 23 250 273 250 273 0.96

3 16 6.2e-05 0.004 17.4 2.3 1 23 339 362 339 362 0.96

4 16 0.0084 0.55 10.7 0.4 2 23 414 435 413 435 0.96

5 16 3.5 2.3e+02 2.5 3.0 1 20 548 567 548 569 0.85

6 16 0.02 1.3 9.6 0.6 1 23 578 600 578 600 0.94

7 16 0.00029 0.019 15.4 2.1 1 23 607 629 607 630 0.95

8 16 0.00045 0.03 14.7 1.4 2 23 638 659 637 659 0.96

9 16 0.014 0.91 10.0 0.1 2 21 686 705 685 709 0.88

10 16 0.51 33 5.1 0.6 1 23 747 770 747 770 0.91

11 16 1.5 99 3.6 2.6 1 21 777 797 777 798 0.94

12 16 0.00057 0.037 14.4 1.2 1 23 807 830 807 830 0.98

13 16 1.6e-05 0.0011 19.3 0.5 1 23 851 874 851 874 0.97

14 16 0.098 6.4 7.4 0.2 1 23 884 906 884 906 0.94

15 16 2.5e-05 0.0016 18.7 3.3 1 23 912 934 912 934 0.99

16 16 5.2e-05 0.0034 17.7 0.9 1 23 940 962 940 962 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	3.5e-05	0.0023	18.2	5.3	1	23	175	198	175	198	0.97
2	16	0.0018	0.12	12.8	3.9	1	23	250	273	250	273	0.96
3	16	6.2e-05	0.004	17.4	2.3	1	23	339	362	339	362	0.96
4	16	0.0084	0.55	10.7	0.4	2	23	414	435	413	435	0.96
5	16	3.5	2.3e+02	2.5	3.0	1	20	548	567	548	569	0.85
6	16	0.02	1.3	9.6	0.6	1	23	578	600	578	600	0.94
7	16	0.00029	0.019	15.4	2.1	1	23	607	629	607	630	0.95
8	16	0.00045	0.03	14.7	1.4	2	23	638	659	637	659	0.96
9	16	0.014	0.91	10.0	0.1	2	21	686	705	685	709	0.88
10	16	0.51	33	5.1	0.6	1	23	747	770	747	770	0.91
11	16	1.5	99	3.6	2.6	1	21	777	797	777	798	0.94
12	16	0.00057	0.037	14.4	1.2	1	23	807	830	807	830	0.98
13	16	1.6e-05	0.0011	19.3	0.5	1	23	851	874	851	874	0.97
14	16	0.098	6.4	7.4	0.2	1	23	884	906	884	906	0.94
15	16	2.5e-05	0.0016	18.7	3.3	1	23	912	934	912	934	0.99
16	16	5.2e-05	0.0034	17.7	0.9	1	23	940	962	940	962	0.98

Sequence Information

Coding Sequence: ATGACAAGAACGTGTAGAATCTGCGGTGGCGCAAATGGACGCTTCTGGATCGAGACGCCAATTGATAAATACGCGGAGAAAACATTCAATCACCTGCTGCTGGAGCTAACAAAACTCGAGGTCACTGTGGATCAAGCTGATAAGCTGCCGCCATGGATCTGCCGCAACTGTGCGCACAGATTAGAAAATGCCTACGACTTTGTGATGCAGGCGAGGGAAACTCACGAACTTTGGCTGCACAAGATGGCAACAGAATCTCTATCGGAGGACACCGAAACTGGGACGTTGGAGTGCCTGCGAGAGACACCCATTCAATTGCTGGAGATTGAGGGCGTCACAATTAAAATGGAGGAGGCAACCGAACCAGCCGTGCCACAAACAGATTCAGTCGGCTCGATTGATCCGCTAATTAAAAAGAGCCGAGAGGATGATGCCAgcaataatgatgatgacgctgatgatgacgatgatgatacTCCGCTCAAGCAGCGCCGGATTGCACGCACAAAACTGCCAACGATGCACAAGTGCAATAAGTGCGACAAGGCCTTCAAATATGTAACGAATCTCTTCAGGCACAAACGACGAGATCACACTCCAGAGTACAGCCAAACCAAAGAACAGGCAGCAGTGGAAAGTGAAAAGACTGATGGCATGAAACCTTTCTTAAACGATATAATCAAGAGCTCCATTGCAGCAACACGCAGCAGCGAGGCAGACTTGGAAAGCGAATTGGCTGATAATTACTACAAGTGCGATCAATGCGACAAATCCTACAAGTACATAATGCTGCTGATCAGACACAAGCACAAGACGCACGCTTCCAACCAGTGTCCATCAGAGCCCAGACCAATTAGAAGAAGCGGTTCGAGTGCAGAGCAAACTAATACTAAACAAGGATCACCGCCTCAGCGCTCGAAACCGACCAGTACAGATTCGCTTGTGCACAGCATCATCAAAGAGATCAACTTACCCGATGAGGACGATGCAGACAGTTCCAGTGCCGACAATTACTACAAGTGCGACCAGTGCGACAAGTCGTACAAATACATTGTGAGTCTCATCAAGCACATGCACAACGAGCACAAGGAATACAGGGATTCCGATGAGGACGAAGATGGGGCAACGTCCTCCAGATATGCAGCAGATGCCACTGCTATGTCGAAGCCGTCGCGCATTGATCGTCGCGTCAAGGGCTTCGATTTGAATCGCTGCCGGCCAAACGGTTCCAAAGAGATTCAGTGCATGATCTGTCTGCGCAGATTCATCAAGTTGCGCGAGCTGCGTGATCACCTGAAAGCCCATCCTAAAGACTTTACATTCGATGCTCATGGCGAGCCGATTGAGCGCATTGCCGAGGGGTTCTATAAGACAGCCGTGGAATCGACAGTTGCGGGCCTGAAGCGACGCATCTTCAATGATCTCAAGGTTGGCATGCTCGGACGCTACTATTCCATAACAAATGAGGCGCGGTACGAGATGAATCTGGACAGCTCGGACACGGACAGCGACGGCGAAGCGGATGTTGTGCAGCGGCACTCGTATGCCTGCGAACTGTGCGACTCCGCCGATGCCGTCTGGCCACGCAAATATCAATTGCACGAGCATCATCGGCAGCAGCACACCTGGCTGGAGGCGCCGCACGTCTGCCAGCGCTGTGACTTCCGCTTCCTGAGCGCGCAGCTGCTCGAGCATCATACGCACAAGTTGTGCCAGAACACCCTGAAGCGCTTCATGTGTGACAAATGTCCACAGCGCTTCTTTTGGCGACGCAATCTACGTGCGCATCTTGTCGAGCATAAAAACAAGCAGGAGACGTATCCGTGTGATCAGTGCTCGCGCAGCTTTCAGGACAAGAGCGCCGTGACGAAGCACAAGCTGATGCACCACGATGTCCACAACGAGCTGTTGCCCTGTCGCTGGTGCACGCGCACCTTCTACCGGCCGGCGCTGTTGCACAAGCATGTGCAGCGTCACGGCTTTAGTGGGGAGGATCTGCCGCTGGCAGAGACACTGCTGGCCGATGCCGCCAAGCCATCCGGTACGAAGACGATTGTCTGCAAACTTTGCGATATGCAGTTCATTAGCATTGGCGACCTGCGGCGACACAACTCGATGCAGGCGCACAGTGAGCAGGTGTCCAACTATATGATAAGCACCGAGGAGGGGTTCGAGCTGCAGCTGGATGAAACGGACGAGAGTGATGAGGAGCCCACGAGTACTGCTGCCAGCCGGTCTTATCGATGCGATCTGTGCGAGATGAGCTTCCTGCGAATGCGTGACATGAGCGAACATCAGTATTCGCTGCACACCTTCGACAAGCTGCCACATTCCTGTGAGCATTGCATTTATAAGACAGTCGATAAGACCATGCTAGAGCACCATCTGAACAAACAGTGTCTGAACGAGGAGAAGAAATTCAAGTGCTCTCGTTGCGGCTACAAATTCATGTGGCGCGAAAATCTGGAGCAGCACATGAGCACTCTGCATCCCAAGTCATCATCTAGTCAGACGCCCGTTGCGGCGACAAAGCGGAGTAGACGTTTCCGATACCAGTGTCCACACTGCTGGCGCTCGTTTGTGGTGCAGCCCAGCCTGGACAAGCACATTCGGGACATGCATGTGGCGAAAAAGAATCCCGGCAAGAAGTATCTATGCTCGCTGTGCGGCCTGGAGTCGCTGACCCCAAATAAGCTCAGCATACACATGCGCCGTCACAACGGCGAGAAGCCATTCAAATGTGATCTCTGCGACATGTCCTTCACCGTGCACTACGAGCTGAAGGTTCATCGCCGCAAGCATACCGGCGAGCGACCCTATCAGTGCACATTCTGTGCCAAGGATTTTGCCCGGCCGGATAAGCTAAGACGGCATGTTTACATGCATAGTGTTAAGCGTTAA
Protein Sequence: MTRTCRICGGANGRFWIETPIDKYAEKTFNHLLLELTKLEVTVDQADKLPPWICRNCAHRLENAYDFVMQARETHELWLHKMATESLSEDTETGTLECLRETPIQLLEIEGVTIKMEEATEPAVPQTDSVGSIDPLIKKSREDDASNNDDDADDDDDDTPLKQRRIARTKLPTMHKCNKCDKAFKYVTNLFRHKRRDHTPEYSQTKEQAAVESEKTDGMKPFLNDIIKSSIAATRSSEADLESELADNYYKCDQCDKSYKYIMLLIRHKHKTHASNQCPSEPRPIRRSGSSAEQTNTKQGSPPQRSKPTSTDSLVHSIIKEINLPDEDDADSSSADNYYKCDQCDKSYKYIVSLIKHMHNEHKEYRDSDEDEDGATSSRYAADATAMSKPSRIDRRVKGFDLNRCRPNGSKEIQCMICLRRFIKLRELRDHLKAHPKDFTFDAHGEPIERIAEGFYKTAVESTVAGLKRRIFNDLKVGMLGRYYSITNEARYEMNLDSSDTDSDGEADVVQRHSYACELCDSADAVWPRKYQLHEHHRQQHTWLEAPHVCQRCDFRFLSAQLLEHHTHKLCQNTLKRFMCDKCPQRFFWRRNLRAHLVEHKNKQETYPCDQCSRSFQDKSAVTKHKLMHHDVHNELLPCRWCTRTFYRPALLHKHVQRHGFSGEDLPLAETLLADAAKPSGTKTIVCKLCDMQFISIGDLRRHNSMQAHSEQVSNYMISTEEGFELQLDETDESDEEPTSTAASRSYRCDLCEMSFLRMRDMSEHQYSLHTFDKLPHSCEHCIYKTVDKTMLEHHLNKQCLNEEKKFKCSRCGYKFMWRENLEQHMSTLHPKSSSSQTPVAATKRSRRFRYQCPHCWRSFVVQPSLDKHIRDMHVAKKNPGKKYLCSLCGLESLTPNKLSIHMRRHNGEKPFKCDLCDMSFTVHYELKVHRRKHTGERPYQCTFCAKDFARPDKLRRHVYMHSVKR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00567692;
90% Identity: iTF_00570569;
80% Identity: -