Basic Information

Insect: Drosophila picticornis
Gene Symbol: -
Assembly: GCA_035043845.1
Location: JAWNMR010000362.1:20041477-20045056[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 3.6e-05 0.0022 18.2 5.3 1 23 175 198 175 198 0.97

2 16 0.0011 0.067 13.6 3.6 1 23 253 276 253 276 0.97

3 16 0.0006 0.037 14.4 3.3 1 23 342 365 342 365 0.96

4 16 0.0087 0.54 10.7 0.4 2 23 417 438 416 438 0.96

5 16 3.6 2.2e+02 2.5 3.0 1 20 551 570 551 572 0.85

6 16 0.021 1.3 9.5 0.6 1 23 581 603 581 603 0.94

7 16 0.00029 0.018 15.4 2.1 1 23 610 632 610 633 0.95

8 16 0.00047 0.029 14.7 1.4 2 23 641 662 640 662 0.96

9 16 0.003 0.19 12.2 0.2 2 20 689 707 688 712 0.89

10 16 0.12 7.3 7.1 0.9 1 23 750 773 750 773 0.95

11 16 1.5 93 3.7 2.2 1 22 780 801 780 801 0.93

12 16 0.00059 0.036 14.4 1.2 1 23 810 833 810 833 0.98

13 16 1.7e-05 0.001 19.3 0.5 1 23 854 877 854 877 0.97

14 16 0.1 6.2 7.4 0.2 1 23 887 909 887 909 0.94

15 16 2.5e-05 0.0016 18.7 3.3 1 23 915 937 915 937 0.99

16 16 5.4e-05 0.0033 17.7 0.9 1 23 943 965 943 965 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	3.6e-05	0.0022	18.2	5.3	1	23	175	198	175	198	0.97
2	16	0.0011	0.067	13.6	3.6	1	23	253	276	253	276	0.97
3	16	0.0006	0.037	14.4	3.3	1	23	342	365	342	365	0.96
4	16	0.0087	0.54	10.7	0.4	2	23	417	438	416	438	0.96
5	16	3.6	2.2e+02	2.5	3.0	1	20	551	570	551	572	0.85
6	16	0.021	1.3	9.5	0.6	1	23	581	603	581	603	0.94
7	16	0.00029	0.018	15.4	2.1	1	23	610	632	610	633	0.95
8	16	0.00047	0.029	14.7	1.4	2	23	641	662	640	662	0.96
9	16	0.003	0.19	12.2	0.2	2	20	689	707	688	712	0.89
10	16	0.12	7.3	7.1	0.9	1	23	750	773	750	773	0.95
11	16	1.5	93	3.7	2.2	1	22	780	801	780	801	0.93
12	16	0.00059	0.036	14.4	1.2	1	23	810	833	810	833	0.98
13	16	1.7e-05	0.001	19.3	0.5	1	23	854	877	854	877	0.97
14	16	0.1	6.2	7.4	0.2	1	23	887	909	887	909	0.94
15	16	2.5e-05	0.0016	18.7	3.3	1	23	915	937	915	937	0.99
16	16	5.4e-05	0.0033	17.7	0.9	1	23	943	965	943	965	0.98

Sequence Information

Coding Sequence: ATGACAAGGACGTGTAGAATCTGCGGTGGCGCAGATGGACGCTTCTGGATCGAGACGCCAATTGATAAATACGCGGAAAAAACATTCAATCATCTGCTGCTGGAGCTAACAAAACTCGAGGTCACTGTAGATCAAGCTGATAAGCTGCCGCCATGGATCTGCCGCAACTGTGCGCACAGATTAGAAAATGCCTACGACTTTGTGCTGCAGGCGAGGGAAACTCACGAGCTTTGGCTGCACAAGATGACAACAGAATCCCTATCGGAGGACACCGAAACTGGGACGTTGGAGTGCCTGCGAGAGACACCCATTCAATTGCTGGAGATTGAGGGCGTCACTATTAAAATGGAGGAGGCAACCGAACCAGCCGTGCCACAAACAGATTCAGTCGGCTCGATTGATCCGCTAAATAAAAAGAGCCGGGAGGATGATGCCAGCAATAATGGTGATGAcgctgatgatgacgatgatgatatTCCGCTCAAGCAGCGCCGGATTGCACGCACAAAACTGCCGACGATGCACAAGTGCAATAAGTGCGACAAGGCCTTCAAATATGTGACGAATCTCTTCAGGCACAAGCGACGAGATCACAGCCCAGAGcacaaccaaaccaaaccaaatacAGAACAGGAAGCAGTGGAAAGTGAAAAGACTGATGGCATGAAACCGTTCTTAAACGATGTGACCAAGAGCTCCATTGCAGCAACTCACAACAGCAATGCAGAcTTGGAGAGCCAATTGGCGGATAATTACTACAAGTGCGATCAATGCGACAAATCTTACAAGTACATAATGCTGCTGATCAGGCACACGCACAAAACGCACGCTTCCAGCCAGTGTCCAGCAGAGCCCAGATCAATTAGAAGAAGCGGTTCGAGTGCAGAGCAAACTAATACTAAACAAGGATCACCGCCTCAGCACTCAAAACCGACCAGCACAGATTCACTTGTGCACAGCATCATCAAAGAGATCAACTTACCCGATGAGGACGATGCAGACAGTTGCAGTGCCGACAATTACTACAAGTGCGACCAGTGCGACAAGTCGTACAAATACGTTGTGAGTCTCAtcaagcacaagcacaaggAGCACATGGAATACAGGGATTCCGATGAGGACGAAGATGGGGCAACGTCCTCCAGATATACAGCAGATGCCACTGCTATGTCGAAGCCGTCGCGCATTGATCGTCGCGTGAAGGGCTTCGATTTGAATCGCTGCCGGCCAAACGGTTCCAAAGAGATTCAGTGCATGATCTGTCTGCGCAGATTCATCAAGTTGCGCGAGCTGCGTGATCACCTGAAAGCCCATCCTAAAGACTTTACATTCGATGCTCATGGCGAGCCGATCGAGCGCATTGCCGAGGGATTCTATAAGACAGCCGTGGAATCCACAGTTGCGGGCCTGAAGCGACGCATCTTCAACGATCTCAAGGTTGGCATGCTCGGACGCTACTATTCCATTACAAATGAGGCGCGGTACGAAATGAATTTGGACAGCTCGGACACGGACAGCGACGGCGAAGCGGATGTTGTGCAGCGGCATTCGTATGCCTGCGAGCTGTGCGACTCCGCCGATGCCGTCTGGCCCCGCAAATATCAATTGCACGAGCATCATCGGCAGCAGCACACCTGGCTGGAGGCGCCGCACGTCTGCCAGCGCTGTGACTTCCGCTTCCTGAGCGCGCAGCTGCTCGAGCATCACACGCACAAGTTGTGCCAGAACACTCTGAAGCGCTTCATGTGCGACAAGTGTCCACAGCGCTTTTTTTGGCGACGCAATCTACGAGCGCATCTTGTCGAGCACAAAAATAAGCAGGAGACGTATCCGTGTGACCAGTGCTCGCGCAGCTTTCAGGACAAGAGCGCCGTGACGAAGCACAAGCTGATGCACCACGATGTCCACAACGAGCTGTTGCCCTGTCGCTGGTGCACGCGCACCTTCTACCGACCGGCGCTGTTGCACAAGCATGTGCAGCGTCACGGCTTTAGTGGGGAGGATCTGCCGCTGGCGGAGACACTGCTGGCGGATGCCGCCAAGCCATCCGGTACGAAGACGATTGTCTGCAAACTTTGCGATATGCACTTTATAAGCATTAGCGACCTGCGGCGACACAACTCGATACTGGCGCACAGTGAGCAGATGTCCAACTATATGATAAGCACCGAGGAGGGATTCGAGCTGCAGCTGGATGAAACGGACGAGAGTGATGAGGAGCCCACGAGTACTGCTGCCAGCCGATCTTATCGATGCGATCTGTGCGAGATGAGCTTCCTGCGAAGGCGCGACATGAGCGAACATCAGTATTCGCTGCACACCTTCGACAAGCTGCCACATTCCTGTGAGCATTGCATTTATAAGACAGTCGATAAGACCATGTTAGAGCACCATCTGAGCACACAGTGTCTTAACGAGGAGAAGAAATTCAAGTGCTCTCGTTGCGGCTACAAATTCATGTGGCGCGAAAATCTGGAGCAGCACATGAGCACTCTGCATCCCAAGTCATCATCTAGTCAGACGCCCGTTGCGGCGACAAAGCGGAGTAGACGTTTCCGATACCAGTGCCCACACTGCTGGCGCTCGTTTGTGGTGCAGCCCAGCCTGGACAAGCACATTCGGGACATGCATGTGGCGAAAAAGAATCCCGGCAAGAAGTATCTATGCTCTCTGTGCGGCCTGGAGTCGCTGACCCCAAATAAGCTCAGCATACACATGCGGCGTCACAACGGCGAGAAGCCATTCAAATGTGATCTCTGCGACATGTCCTTCACCGTGCACTACGAGCTGAAGGTTCATCGCCGCAAGCATACCGGCGAGCGACCCTATCAGTGCACATTCTGTGCCAAGGATTTCGCCCGGCCGGATAAACTAAGACGGCATGTTTACATGCACAGCGTTAAGCGTTAA
Protein Sequence: MTRTCRICGGADGRFWIETPIDKYAEKTFNHLLLELTKLEVTVDQADKLPPWICRNCAHRLENAYDFVLQARETHELWLHKMTTESLSEDTETGTLECLRETPIQLLEIEGVTIKMEEATEPAVPQTDSVGSIDPLNKKSREDDASNNGDDADDDDDDIPLKQRRIARTKLPTMHKCNKCDKAFKYVTNLFRHKRRDHSPEHNQTKPNTEQEAVESEKTDGMKPFLNDVTKSSIAATHNSNADLESQLADNYYKCDQCDKSYKYIMLLIRHTHKTHASSQCPAEPRSIRRSGSSAEQTNTKQGSPPQHSKPTSTDSLVHSIIKEINLPDEDDADSCSADNYYKCDQCDKSYKYVVSLIKHKHKEHMEYRDSDEDEDGATSSRYTADATAMSKPSRIDRRVKGFDLNRCRPNGSKEIQCMICLRRFIKLRELRDHLKAHPKDFTFDAHGEPIERIAEGFYKTAVESTVAGLKRRIFNDLKVGMLGRYYSITNEARYEMNLDSSDTDSDGEADVVQRHSYACELCDSADAVWPRKYQLHEHHRQQHTWLEAPHVCQRCDFRFLSAQLLEHHTHKLCQNTLKRFMCDKCPQRFFWRRNLRAHLVEHKNKQETYPCDQCSRSFQDKSAVTKHKLMHHDVHNELLPCRWCTRTFYRPALLHKHVQRHGFSGEDLPLAETLLADAAKPSGTKTIVCKLCDMHFISISDLRRHNSILAHSEQMSNYMISTEEGFELQLDETDESDEEPTSTAASRSYRCDLCEMSFLRRRDMSEHQYSLHTFDKLPHSCEHCIYKTVDKTMLEHHLSTQCLNEEKKFKCSRCGYKFMWRENLEQHMSTLHPKSSSSQTPVAATKRSRRFRYQCPHCWRSFVVQPSLDKHIRDMHVAKKNPGKKYLCSLCGLESLTPNKLSIHMRRHNGEKPFKCDLCDMSFTVHYELKVHRRKHTGERPYQCTFCAKDFARPDKLRRHVYMHSVKR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00567692;
90% Identity: iTF_00570569;
80% Identity: -