Basic Information

Insect: Drosophila mayaguana
Gene Symbol: -
Assembly: GCA_037075325.1
Location: JBAMCG010000037.1:1302273-1305408[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 8.5e-05 0.0058 17.0 5.8 1 23 173 196 173 196 0.96

2 17 0.0017 0.12 12.9 5.1 1 23 236 259 236 259 0.96

3 17 0.0029 0.19 12.2 2.8 1 23 316 339 316 339 0.94

4 17 0.0036 0.24 11.9 0.7 2 23 391 412 390 412 0.97

5 17 0.035 2.4 8.8 2.3 1 23 492 518 492 518 0.96

6 17 2.9 2e+02 2.8 0.7 1 19 525 543 525 546 0.72

7 17 0.026 1.8 9.2 0.6 1 23 555 577 555 577 0.93

8 17 0.00028 0.019 15.4 2.1 1 23 584 606 584 607 0.95

9 17 0.00045 0.031 14.8 1.4 2 23 615 636 614 636 0.96

10 17 0.0027 0.19 12.3 0.4 3 22 664 683 663 686 0.91

11 17 0.0045 0.31 11.6 1.0 1 23 722 745 722 745 0.96

12 17 0.25 17 6.1 1.7 1 22 752 773 752 773 0.97

13 17 0.012 0.84 10.2 2.4 1 23 782 805 782 805 0.97

14 17 1.6e-05 0.0011 19.3 0.5 1 23 824 847 824 847 0.97

15 17 0.038 2.6 8.7 0.2 1 23 857 879 857 879 0.94

16 17 2.4e-05 0.0017 18.7 3.3 1 23 885 907 885 907 0.99

17 17 5.2e-05 0.0035 17.7 0.9 1 23 913 935 913 935 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	8.5e-05	0.0058	17.0	5.8	1	23	173	196	173	196	0.96
2	17	0.0017	0.12	12.9	5.1	1	23	236	259	236	259	0.96
3	17	0.0029	0.19	12.2	2.8	1	23	316	339	316	339	0.94
4	17	0.0036	0.24	11.9	0.7	2	23	391	412	390	412	0.97
5	17	0.035	2.4	8.8	2.3	1	23	492	518	492	518	0.96
6	17	2.9	2e+02	2.8	0.7	1	19	525	543	525	546	0.72
7	17	0.026	1.8	9.2	0.6	1	23	555	577	555	577	0.93
8	17	0.00028	0.019	15.4	2.1	1	23	584	606	584	607	0.95
9	17	0.00045	0.031	14.8	1.4	2	23	615	636	614	636	0.96
10	17	0.0027	0.19	12.3	0.4	3	22	664	683	663	686	0.91
11	17	0.0045	0.31	11.6	1.0	1	23	722	745	722	745	0.96
12	17	0.25	17	6.1	1.7	1	22	752	773	752	773	0.97
13	17	0.012	0.84	10.2	2.4	1	23	782	805	782	805	0.97
14	17	1.6e-05	0.0011	19.3	0.5	1	23	824	847	824	847	0.97
15	17	0.038	2.6	8.7	0.2	1	23	857	879	857	879	0.94
16	17	2.4e-05	0.0017	18.7	3.3	1	23	885	907	885	907	0.99
17	17	5.2e-05	0.0035	17.7	0.9	1	23	913	935	913	935	0.98

Sequence Information

Coding Sequence: ATGACAAGAACTTGCAGAGTCTGTGGTGGAACAAATGGACGTTATTGGATCGAGACGCCACTTAATAAATACGCAAATAAAACTTACAATCAATTGCTGCTGGAGTTAACAAAGCTCGAGGGTGGTTTAGATTCCGGCGACAAGTTGCCGCCCTGGATTTGCCAAAACTGTTCTCAAAGATTAGAGAATGCATACGACTTTGTGCAGCAAGCTCGTAATACTTATGAACTTTGGCTGCAGAAGATCTCAGGAGAGTGTCTCTCAGAGGATACCGAAACAGCCACTTTAGAGTGTTTGCGCGAGACTCCAATACAATTACTGGATATTGAGGATATCACAATTAAAATGGAAGAGTCCACAGAGCCTGTCACGCCGTCCACAACAGATCCAACAAACACAATTGATCCTTTGATTAAGAAGAGCAATGTGGATGATGACAGTGATGGCagtgatgatgacgatgatgatgtaCCCCTAAAGCAACGCCGGGCAGCTCAGACGAAATTTCCCATGCTACACAGGTGCAATAAATGCGACAAGTCCTTTAAATATGTAACTAATCTCTTCAGGCACAAGCAACGAGATCACAGTTCAACTAAGCCACAAGAAGTAGAAGAGACACCTAATCAGTCGGAAAAGCTCTCCAGCTCTATTGACGGCAAGAGCTGCTCGGCAAACTTGGATAACGAATCCGTCGATAACTACTACAAATGTGATCATTGCGACAAGTCCTACAAGTATATAATGCTTCTTATCAAGCATAAGCATAAGGCGCATGTCTCCAGCCAGATATCAGCACAACCCAAGCTAATTGAGGATAACAGCCAAGAATCACAGCCGCAGCGCTCGAAGCCGAAAAGCACAGATTCCCTTGTGCACAGCATCATTAAGGAGATCAcCATTCCGGATGAGGATGATGCAGATAGCTCAAGTGCAGATAATTACTACAAATGTGATCAATGCGAAAAGTCCTATAAGTACATTGTTAGTCTCATCAAGCACAAGCATAACGAGCACAATGCGTATAAGGATtctgatgaagatgaagatgaagctACGCCAACTAGATTTGCAACGGACACGTCAGCCGTGTCGAAGCCCTCACGCATCGATCGTCGCGTCAAAGGCTTCGATTTGAATCGGTGCAAACCAAATGGCTCAAAGGAAATTCAATGCATGATCTGTCTGCGTAGATTTATCAAACTTCGCGAATTGCGTGACCATTTAAAATCTCATCCTAAGGACTTTGGATTCGATGCTCATGGCGAGCCTATTGAACGTATTGCAGAGGGCTTTTATAAGACCGCCGTTGAATCTACAGCTGCTGGCTTAAAACGGCGAATTTTCAATGATCTCAAAGTGGGCATGTACGGTCGCTATTACTCCATAACGAATGAGGCGCGATATGAGATGAACTTGGACAGCTCCGACACGGATAGTGATGGCGAAGCGGATGTTGTGGAGAGACACAGTTATTCATGTGAGCTATGTAATTCACCCGAGACCGTCTTCCCACGCAAATACCAATTGCACGAACACCATCGGCAGGAGCATACCTGGCTGGAGGCACCACATGTCTGTCAGCGTTGTGATGCTCGTTTCTTGAGCGCTCAATTGCTCGATCATCATACGCTCAAGCTGTGTCAGAACACGCTCAAACGGTTCATGTGCGACAAGTGTCCGCAGCGATTTTTCTGGCGGCGCAATTTGCGCGCTCATCTTGTCGATCACAAAAACAAGCAAGAGACATACCCATGCGATCAGTGCTCACGCAGCTTTCAGGATAAGAGTGCCGTGACCAAGCACAAGCTAATGCACCACGACGGCAGCAATGAATTGCTGCCCTGTCGTTGGTGCACACGCACTTTCTATCGACCCGCACTTTTGCACAAGCATGTACAGCGGCATGGGTTCAGAGGTGAGGATCTTCCCCTGGCAGAGACACTACTAGCGGATGCTGCCAAGACTCCCGGCCCAAAATCCATCTTATGCAAACTATGCGACATTCATTTCATTACAATTGGCGATCTGCGACGACACATCTCGATGCAGGCCCATACTGAAGAGGCGCCCAACTATATGATAAGCACCGAAGAGGGCTTTGAGCTGCTTCTGGATGAAACGGATGAGAGCGACGATGAGGCTGTAGGTTCTGGCAAAACTTATCGCTGTGCTCTATGCGACATGAGCTTTCAGCGGCGGCGCGACATGAGCGAACATCAGTATTCTCTGCACACCTTCGACAAGTTGCCCTATTCCTGCGAGCATTGTATTTTCAAGACTGTAGACAAGACTATGCTGGAGCATCATTTACGAACGCAATGCCTTAACCAggaaaagaaattcaaatgctCACGCTGTGGCTACAAATTCATGTGGCACGAAAATCTAGAGCTGCACATGTCGAGCCAACATTCCAAGTCATCCAGTCAAGCACCTGTTACGACCAAGCGAAGTAGACGGTTTAGGTATCAATGTCCACACTGCTGGCGATCCTTTGTTGTACAACCTAGCCTGGACAAGCACATACGCGACATGCATGTTGCCAAAAAGAATCCGGGTAAAAAATATCTTTGCTCACTGTGTGGTCTGGAGTCATTGACACCCAACAAGCTGAACATACATATGCGTCGACACAATGGCGAAAAGCCTTTCAAATGCGATCTCTGTGACATGTCCTTCACCGTGCACTATGAACTGAAAGTCCATCGACGCAAGCATACAGGCGAACGACCCTATCAATGCACGTTCTGTGCCAAGGACTTCGCCCGGCCAGATAAACTGAGGCGACATGTCTACATGCATAGCGTTAAGCGTTAA
Protein Sequence: MTRTCRVCGGTNGRYWIETPLNKYANKTYNQLLLELTKLEGGLDSGDKLPPWICQNCSQRLENAYDFVQQARNTYELWLQKISGECLSEDTETATLECLRETPIQLLDIEDITIKMEESTEPVTPSTTDPTNTIDPLIKKSNVDDDSDGSDDDDDDVPLKQRRAAQTKFPMLHRCNKCDKSFKYVTNLFRHKQRDHSSTKPQEVEETPNQSEKLSSSIDGKSCSANLDNESVDNYYKCDHCDKSYKYIMLLIKHKHKAHVSSQISAQPKLIEDNSQESQPQRSKPKSTDSLVHSIIKEITIPDEDDADSSSADNYYKCDQCEKSYKYIVSLIKHKHNEHNAYKDSDEDEDEATPTRFATDTSAVSKPSRIDRRVKGFDLNRCKPNGSKEIQCMICLRRFIKLRELRDHLKSHPKDFGFDAHGEPIERIAEGFYKTAVESTAAGLKRRIFNDLKVGMYGRYYSITNEARYEMNLDSSDTDSDGEADVVERHSYSCELCNSPETVFPRKYQLHEHHRQEHTWLEAPHVCQRCDARFLSAQLLDHHTLKLCQNTLKRFMCDKCPQRFFWRRNLRAHLVDHKNKQETYPCDQCSRSFQDKSAVTKHKLMHHDGSNELLPCRWCTRTFYRPALLHKHVQRHGFRGEDLPLAETLLADAAKTPGPKSILCKLCDIHFITIGDLRRHISMQAHTEEAPNYMISTEEGFELLLDETDESDDEAVGSGKTYRCALCDMSFQRRRDMSEHQYSLHTFDKLPYSCEHCIFKTVDKTMLEHHLRTQCLNQEKKFKCSRCGYKFMWHENLELHMSSQHSKSSSQAPVTTKRSRRFRYQCPHCWRSFVVQPSLDKHIRDMHVAKKNPGKKYLCSLCGLESLTPNKLNIHMRRHNGEKPFKCDLCDMSFTVHYELKVHRRKHTGERPYQCTFCAKDFARPDKLRRHVYMHSVKR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00567692;
90% Identity: iTF_00516420; iTF_00479626; iTF_00551739; iTF_00554527; iTF_00549696; iTF_00532532; iTF_00476779; iTF_00545396; iTF_00544644; iTF_00493816; iTF_00559641; iTF_00599740; iTF_00473214;
80% Identity: -