Basic Information

Insect: Drosophila buzzatii
Gene Symbol: -
Assembly: GCA_035045845.1
Location: JAWNOS010000488.1:263277-266407[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 8.5e-05 0.0067 17.0 5.0 1 23 170 193 170 193 0.97

2 17 0.0017 0.13 13.0 3.4 1 23 233 256 233 256 0.96

3 17 0.00083 0.065 13.9 2.8 1 23 313 336 313 336 0.94

4 17 0.0035 0.28 12.0 0.7 2 23 386 407 385 407 0.97

5 17 0.19 15 6.5 2.6 1 23 487 513 487 513 0.94

6 17 9.2 7.2e+02 1.2 1.1 1 19 520 538 520 541 0.72

7 17 0.026 2 9.3 0.6 1 23 550 572 550 572 0.93

8 17 0.00028 0.022 15.4 2.1 1 23 579 601 579 602 0.95

9 17 0.00045 0.035 14.8 1.4 2 23 610 631 609 631 0.96

10 17 0.0046 0.36 11.6 0.1 3 22 659 678 658 681 0.91

11 17 0.041 3.2 8.6 2.4 1 23 717 740 717 740 0.96

12 17 0.25 20 6.1 1.7 1 22 747 768 747 768 0.97

13 17 0.012 0.97 10.2 2.4 1 23 777 800 777 800 0.97

14 17 1.6e-05 0.0013 19.3 0.5 1 23 819 842 819 842 0.97

15 17 0.038 3 8.7 0.2 1 23 852 874 852 874 0.94

16 17 2.4e-05 0.0019 18.8 3.3 1 23 880 902 880 902 0.99

17 17 5.1e-05 0.004 17.7 0.9 1 23 908 930 908 930 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	8.5e-05	0.0067	17.0	5.0	1	23	170	193	170	193	0.97
2	17	0.0017	0.13	13.0	3.4	1	23	233	256	233	256	0.96
3	17	0.00083	0.065	13.9	2.8	1	23	313	336	313	336	0.94
4	17	0.0035	0.28	12.0	0.7	2	23	386	407	385	407	0.97
5	17	0.19	15	6.5	2.6	1	23	487	513	487	513	0.94
6	17	9.2	7.2e+02	1.2	1.1	1	19	520	538	520	541	0.72
7	17	0.026	2	9.3	0.6	1	23	550	572	550	572	0.93
8	17	0.00028	0.022	15.4	2.1	1	23	579	601	579	602	0.95
9	17	0.00045	0.035	14.8	1.4	2	23	610	631	609	631	0.96
10	17	0.0046	0.36	11.6	0.1	3	22	659	678	658	681	0.91
11	17	0.041	3.2	8.6	2.4	1	23	717	740	717	740	0.96
12	17	0.25	20	6.1	1.7	1	22	747	768	747	768	0.97
13	17	0.012	0.97	10.2	2.4	1	23	777	800	777	800	0.97
14	17	1.6e-05	0.0013	19.3	0.5	1	23	819	842	819	842	0.97
15	17	0.038	3	8.7	0.2	1	23	852	874	852	874	0.94
16	17	2.4e-05	0.0019	18.8	3.3	1	23	880	902	880	902	0.99
17	17	5.1e-05	0.004	17.7	0.9	1	23	908	930	908	930	0.98

Sequence Information

Coding Sequence: ATGACAAGAACATGCAGAGTCTGTGGTGCTACAAATGGACATTATTGGATCGAGAAACCTATTAATAAATACGCAGATAAGACATATAATCAACTGCTGGTGGAGTTAACAAGGCTCGAGGTTGGCTTAGACCAAGCCGACAAGTTGCCGCCCTGGATTTGCTACAACTGTTCACAGAGATTAGAGAATGCATACGACTTTGTGCAGCAGGCGCGTAAAACACATGAGCTCTGGCTTCAAAAACTGTCCAGAGAATGTCTCACAGATGACACCGATATAGCTACTCTGGAGTGTTTGCGCGAAACTCCAATACAATTGCTGGATATAGAAGgtataacaattaaaatggaaGAGCCCGCAGAGCCTGTCACGCCATCAGCAGATCCAACCAACACAATTGATCCTTTGATTAAGAAAAGCAATGTAGATGATGACAgcaatgatgatgacgatgatgatgtgcCCCTTAAACAACGTCGAGCAGCGCAGACTAAATTTTCGATGTTGCATAAGTGCAATAAATGCGATAAGGCTTTTAAATATGTTACCAATCTCTTTAGGCACAAGCAGCGGGATCACAGTTCATCTAAGTCAGAAGAAGTAGGAGAGACCCCAAATCAGGCGGTTCCAACCTCCAGCTCTATTAAGGCAAACAGTTGTTTGACAAActtgGATAATGAATCAGCCGATAACTACTACAAATGCGATCAATGCGACAAGTCTTACAAGTACATAATGCTTCTTATTAAGCATAAGCATAAGGAGCATGTTTCCAGCCAGATATCAGCACAACCCAATCCAATTAAAAAGACAGCAAATGAAACCCATCGGCAACACTCGAAGCCTTCAAGCACAGACTCCCTTGTACACAGCATAATTAAGGAGATAATCATTCCGGATGAGGATGATGCAGACAACTCTAGTGCAGACAATTACTATAAATGCGATCAATGCGACAAGTCCTACAAGTACATTGTGAGTCTCatcaagcacaagcacaacgAGCACAAGGCATATAAAGATTctgatgaagatgaagacACCTCAACTATATACGCAACGGACACATCAGCCATGTCAAAGCCCTCACGCATCGATCGTCGCGTCAAAGGCTTCGATTTGAATCGTTGCAAGCCGAATGGCTCTAAGGAAATTCAATGCATGATCTGTCTGCGCCGATTTATCAAACTGCGTGAGTTGCGTGACCATTTAAAATCTCATCCTCAGGACTTTGGTTTCGAGGTTCATGGCGAGCCCATTGAACGAATTGCAGAGGGCTTTTATAAGACCGCTGTAGAATCCACAGCTGACGGTTTAAAGCGGCGCATTTTCAATGATCTCAGTATGGGCATGTACGGACGCTACTATTCCATAACGAATGAGGCTAAATATGAGATGAATCTGGACAGCTCCGACACAGACAGTGATGGTGAAGCGGATATTGTGGAGCGACACAGTTATTCATGTGAGCTATGTAAATCACCCGATGCCGTTTTCCCACGAAAATACCAATTGCACGAGCACCATCGGCAGAGGCATACCTGGCTAGAAGCCCCTCATGTCTGTCAGCGTTGCGATTCGCGATTTCTGAGCGCTCAGCTGCTGGATCATCACACGCTCAAACTGTGTCAAAACACGCTCAAACGATTCATGTGTGACAAGTGTCCTCAACGTTTTTTCTGGCGACGCAATTTGCGCGCGCATCTTGTAGATCACAAAAACAAGCAAGAGACATACCCATGTGATCAGTGCTCTCGAAGTTTTCAGGATAAGAGCGCCGTAACGAAGCACAAGCTAATGCACCATGACGGCAGTAATGAATTGCTGCCCTGTCGTTGGTGCACACGCACATTCTATCGACCCGCACTTTTGCACAAGCATGTACAGCGACATGGGTTCAGAGGTGAGGATCTTCCCTTGGCTGAGACACTACTAGCGGATGCTGCCAAGACTTCCGGACCAAAGTCCATCTTATGCAAACTATGCGACATTCAGTTCATTACCATTGGCGATCTGCGACGACACATCACGATGCAGGCGCACACAGAAGAAACACCCAACTATATGATAAGCACCGAAGAGGGCTTTGAGCTGCTTCTGGATGAAACGGATGAGAGCGACGATGAGGCTGTAGGTTCTGGCAAAACCTATCGATGTGCTCTGTGCGACATGAACTTTCATCGACGACGCGACATGAGCGAGCATCAGTATTCTCTGCACACATTTGACAAGTTGCCCTATTCCTGCGAGCATTGCATTTTCAAGACCGTAGACAAGACTATGCTGGAACACCATTTGCGAACGCAATGCCTTAACCAGGAAAAGAAATTCAAGTGTTCACGCTGTGGCTACAAATTCATGTGGCACGAAAATCTGGAGTTGCACATGTCAAGCCAACATTCCAAGTCATCCAGTCAGGCACCTGTTACGATCAAACGAAGCAGACGTTTTAGATATCAATGTCCACATTGCTGGCGGTCATTTGTTGTACAACCTAGCCTGGACAAACATATACGCGACATGCATGTCTCCAAAAAGAATCCAGGCAAGAAATATCTTTGCTCACTTTGTGGCCTAGAGTCATTAACACCAAACAAActaaacatacatatgcgcCGGCACAACGGCGAGAAACCTTTCAAATGCGATCTCTGCGACATGTCCTTTACCGTGCATTACGAACTGAAAGTCCATCGACGCAAGCACACGGGCGAACGACCCTATCAATGCACATTCTGTGCCAAGGATTTCGCCAGGCCAGATAAGCTAAGGCGACATGTCTACATGCATAGCGTGAAGCGTTAA
Protein Sequence: MTRTCRVCGATNGHYWIEKPINKYADKTYNQLLVELTRLEVGLDQADKLPPWICYNCSQRLENAYDFVQQARKTHELWLQKLSRECLTDDTDIATLECLRETPIQLLDIEGITIKMEEPAEPVTPSADPTNTIDPLIKKSNVDDDSNDDDDDDVPLKQRRAAQTKFSMLHKCNKCDKAFKYVTNLFRHKQRDHSSSKSEEVGETPNQAVPTSSSIKANSCLTNLDNESADNYYKCDQCDKSYKYIMLLIKHKHKEHVSSQISAQPNPIKKTANETHRQHSKPSSTDSLVHSIIKEIIIPDEDDADNSSADNYYKCDQCDKSYKYIVSLIKHKHNEHKAYKDSDEDEDTSTIYATDTSAMSKPSRIDRRVKGFDLNRCKPNGSKEIQCMICLRRFIKLRELRDHLKSHPQDFGFEVHGEPIERIAEGFYKTAVESTADGLKRRIFNDLSMGMYGRYYSITNEAKYEMNLDSSDTDSDGEADIVERHSYSCELCKSPDAVFPRKYQLHEHHRQRHTWLEAPHVCQRCDSRFLSAQLLDHHTLKLCQNTLKRFMCDKCPQRFFWRRNLRAHLVDHKNKQETYPCDQCSRSFQDKSAVTKHKLMHHDGSNELLPCRWCTRTFYRPALLHKHVQRHGFRGEDLPLAETLLADAAKTSGPKSILCKLCDIQFITIGDLRRHITMQAHTEETPNYMISTEEGFELLLDETDESDDEAVGSGKTYRCALCDMNFHRRRDMSEHQYSLHTFDKLPYSCEHCIFKTVDKTMLEHHLRTQCLNQEKKFKCSRCGYKFMWHENLELHMSSQHSKSSSQAPVTIKRSRRFRYQCPHCWRSFVVQPSLDKHIRDMHVSKKNPGKKYLCSLCGLESLTPNKLNIHMRRHNGEKPFKCDLCDMSFTVHYELKVHRRKHTGERPYQCTFCAKDFARPDKLRRHVYMHSVKR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00567692;
90% Identity: iTF_00540521;
80% Identity: -