Basic Information

Insect: Drosophila melanocephala
Gene Symbol: -
Assembly: GCA_037043625.1
Location: JBAMBD010000012.1:39475-43036[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 3.3e-05 0.0022 18.3 5.3 1 23 175 198 175 198 0.97

2 16 0.0018 0.12 12.8 3.9 1 23 234 257 234 257 0.96

3 16 6e-05 0.0039 17.5 2.3 1 23 323 346 323 346 0.96

4 16 0.0081 0.54 10.8 0.4 2 23 398 419 397 419 0.96

5 16 3.4 2.2e+02 2.5 3.0 1 20 532 551 532 553 0.85

6 16 0.019 1.3 9.6 0.6 1 23 562 584 562 584 0.94

7 16 0.00028 0.018 15.4 2.1 1 23 591 613 591 614 0.95

8 16 0.00044 0.029 14.7 1.4 2 23 622 643 621 643 0.96

9 16 0.013 0.89 10.1 0.1 2 21 670 689 669 693 0.88

10 16 0.5 33 5.1 0.6 1 23 731 754 731 754 0.91

11 16 1.5 97 3.7 2.6 1 21 761 781 761 782 0.94

12 16 0.00055 0.036 14.4 1.2 1 23 791 814 791 814 0.98

13 16 1.6e-05 0.001 19.3 0.5 1 23 835 858 835 858 0.97

14 16 0.094 6.2 7.4 0.2 1 23 868 890 868 890 0.94

15 16 2.4e-05 0.0016 18.7 3.3 1 23 896 918 896 918 0.99

16 16 5e-05 0.0033 17.7 0.9 1 23 924 946 924 946 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	3.3e-05	0.0022	18.3	5.3	1	23	175	198	175	198	0.97
2	16	0.0018	0.12	12.8	3.9	1	23	234	257	234	257	0.96
3	16	6e-05	0.0039	17.5	2.3	1	23	323	346	323	346	0.96
4	16	0.0081	0.54	10.8	0.4	2	23	398	419	397	419	0.96
5	16	3.4	2.2e+02	2.5	3.0	1	20	532	551	532	553	0.85
6	16	0.019	1.3	9.6	0.6	1	23	562	584	562	584	0.94
7	16	0.00028	0.018	15.4	2.1	1	23	591	613	591	614	0.95
8	16	0.00044	0.029	14.7	1.4	2	23	622	643	621	643	0.96
9	16	0.013	0.89	10.1	0.1	2	21	670	689	669	693	0.88
10	16	0.5	33	5.1	0.6	1	23	731	754	731	754	0.91
11	16	1.5	97	3.7	2.6	1	21	761	781	761	782	0.94
12	16	0.00055	0.036	14.4	1.2	1	23	791	814	791	814	0.98
13	16	1.6e-05	0.001	19.3	0.5	1	23	835	858	835	858	0.97
14	16	0.094	6.2	7.4	0.2	1	23	868	890	868	890	0.94
15	16	2.4e-05	0.0016	18.7	3.3	1	23	896	918	896	918	0.99
16	16	5e-05	0.0033	17.7	0.9	1	23	924	946	924	946	0.98

Sequence Information

Coding Sequence: ATGACAAGAACGTGTAGAATCTGCGGTGGCGCAAATGGACGCTTCTGGATCGAGACGCCAATTGATAAATACGCGGAGAAAACATTCAATCACCTGCTGCTGGAGCTAACAAAACTCGAGGTCACTGTGGATCAAGCTGATAAGCTGCCGCCATGGATCTGCCGCAACTGTGCGCACAGATTAGAAAATGCCTACGACTTTGTGATGCAGGCGAGGGAAACTCACGAACTTTGGCTGCACAAGATGCCAACAGAATCTCTATCGGAGGACACCGAAACTGGGACGTTGGAGTGCCTGCGAGAGACACCCATTCAATTGCTGGAGATTGAGGGCGTCACAATTAAAATGGAGGAGGCAACCGAACCAGCTGTTCCACAAACAGATTCAGTCGTCTCGATTGATCCGCTAATTAAAAAGAGCCGAGAGGATGATGCCAgcaataatgatgatgacgctgatgatgacgatgatgatacTCCGCTCAAGCAGCGCCGGATTGCACGCACAAAACTGCCGACGATGCACAAGTGCAATAAGTGCGACAAGGCCTTCAAATATGTAACGAATCTCTTCAGGCACAAACGACGAGATCACACTCCAGAGTACAGCCAAACCAAAGAACATGCAGCATGGAAAAGCTCCATTGCAGCAACACGCAGCAGCGAGGCAGACTTGGAAAGCGAATTGGCTGATAATTACTACAAGTGCGATCAATGCGACAAATCCTACAAGTACATAATGCTGCTGATCAGACACAAGCACAAGACGCACGCTTCCAACCAGTGTCCATCAGAGCCCAGACCAATTAGAAGAAGCGGTTCGAGTGCAGAGCAAACTAATACTAAACAAGGATCACCGCCTCAGCGCTCGAAACCGACCAGTACAGATTCGCTTGTGCACAGCATCATCAAAGAGATCAACTTACCCGATGAGGACGATGCAGACAGTTCCAGTGCCGACAATTACTACAAGTGCGACCAGTGCGACAAGTCGTACAAATACATTGTGAGTCTCATCAAGCACATGCACAACGAGCACAAGGAATACAGGGATTCCGATGAGGACGAAGATGGGGCAACGTCCTCCAGATATGCAGCAGATGCCACTGCTATGTCGAAGCCGTCGCGCATTGATCGTCGCGTCAAGGGCTTCGATTTGAATCGCTGCCGGCCAAACGGTTCCAAAGAGATTCAGTGCATGATCTGTCTGCGCAGATTCATCAAGTTGCGCGAGCTGCGTGATCACCTGAAAGCCCATCCTAAAGACTTTACATTCGATGCTCATGGCGAGCCGATTGAGCGCATTGCCGAGGGGTTCTATAAGACAGCCGTGGAATCGACAGTTGCGGGCCTGAAACGACGCATCTTCAATGATCTCAAGGTTGGCATGCTCGGACGCTACTATTCCATAACAAATGAGGCGCGGTACGAGATGAATCTGGACAGCTCGGACACGGACAGCGACGGCGAAGCGGATGTTGTGCAGCGGCACTCGTATGCCTGCGAACTGTGCGACTCCGCCGATGCCGTCTGGCCACGCAAATATCAATTGCACGAGCATCATCGGCAGCAGCACACCTGGCTGGAGGCGCCGCACGTCTGCCAGCGCTGCGACTTCCGCTTCCTGAGCGCGCAGCTGCTCGAGCATCATACGCACAAGTTGTGCCAGAACACCCTGAAGCGCTTCATGTGCGACAAATGTCCACAGCGCTTCTTTTGGCGACGCAATCTACGTGCGCATCTTGTCGAGCATAAAAACAAGCAGGAGACGTATCCATGTGATCAGTGCTCGCGCAGCTTTCAGGACAAGAGCGCCGTGACGAAGCACAAGCTGATGCACCACGATGTCCACAACGAGCTGTTGCCCTGTCGCTGGTGCACGCGCACCTTCTACCGGCCGGCGCTGTTGCACAAGCATGTGCAGCGTCACGGCTTTAGTGGGGAGGATCTGCCGCTGGCAGAGACACTGCTGGCCGATGCCGCCAAGCCATCCGGTACGAAGACGATTGTCTGCAAACTTTGCGATATGCAGTTCATTAGCATTGGCGACCTGCGGCGACACAACTCGATGCAGGCGCACAGTGAGCAGGTGTCCAACTATATGATAAGCACCGAGGAGGGGTTCGAGCTGCAGCTGGATGAAACGGACGAGAGTGATGAGGAACCCACGAGTACTGCTGCCAGCCGGTCTTATCGATGCGATCTGTGCGAGATGAGCTTCCTGCGAATGCGTGACATGAGCGAACATCAGTATTCGCTGCACACCTTCGACAAGCTGCCACATTCCTGTGAGCATTGCATTTATAAGACAGTCGATAAGACCATGCTAGAGCACCATCTGAACAAACAGTGTCTGAACGAGGAGAAGAAATTCAAGTGCTCTCGTTGCGGCTACAAATTCATGTGGCGCGAAAATCTGGAGCAGCACATGAGCACTCTGCATCCCAAGTCATCATCTAGTCAGACGCCCGTTGCGGCGACAAAGCGGAGTAGACGTTTCCGATACCAGTGTCCACACTGCTGGCGCTCGTTTGTGGTGCAGCCCAGCCTGGACAAGCACATTCGGGACATGCATGTGGCGAAAAAGAATCCCGGCAAGAAGTATCTATGCTCGCTGTGCGGCCTGGAGTCGCTGACCCCAAATAAGCTCAGCATACACATGCGCCGTCACAACGGCGAGAAGCCATTCAAATGTGATCTCTGCGACATGTCCTTCACCGTGCACTACGAGCTGAAGGTTCATCGCCGCAAGCATACCGGCGAGCGACCCTATCAGTGCACATTCTGTGCCAAGGATTTCGCCCGGCCGGATAAGCTAAGACGGCATGTTTACATGCATAGTGTTAAGCGTTAA
Protein Sequence: MTRTCRICGGANGRFWIETPIDKYAEKTFNHLLLELTKLEVTVDQADKLPPWICRNCAHRLENAYDFVMQARETHELWLHKMPTESLSEDTETGTLECLRETPIQLLEIEGVTIKMEEATEPAVPQTDSVVSIDPLIKKSREDDASNNDDDADDDDDDTPLKQRRIARTKLPTMHKCNKCDKAFKYVTNLFRHKRRDHTPEYSQTKEHAAWKSSIAATRSSEADLESELADNYYKCDQCDKSYKYIMLLIRHKHKTHASNQCPSEPRPIRRSGSSAEQTNTKQGSPPQRSKPTSTDSLVHSIIKEINLPDEDDADSSSADNYYKCDQCDKSYKYIVSLIKHMHNEHKEYRDSDEDEDGATSSRYAADATAMSKPSRIDRRVKGFDLNRCRPNGSKEIQCMICLRRFIKLRELRDHLKAHPKDFTFDAHGEPIERIAEGFYKTAVESTVAGLKRRIFNDLKVGMLGRYYSITNEARYEMNLDSSDTDSDGEADVVQRHSYACELCDSADAVWPRKYQLHEHHRQQHTWLEAPHVCQRCDFRFLSAQLLEHHTHKLCQNTLKRFMCDKCPQRFFWRRNLRAHLVEHKNKQETYPCDQCSRSFQDKSAVTKHKLMHHDVHNELLPCRWCTRTFYRPALLHKHVQRHGFSGEDLPLAETLLADAAKPSGTKTIVCKLCDMQFISIGDLRRHNSMQAHSEQVSNYMISTEEGFELQLDETDESDEEPTSTAASRSYRCDLCEMSFLRMRDMSEHQYSLHTFDKLPHSCEHCIYKTVDKTMLEHHLNKQCLNEEKKFKCSRCGYKFMWRENLEQHMSTLHPKSSSSQTPVAATKRSRRFRYQCPHCWRSFVVQPSLDKHIRDMHVAKKNPGKKYLCSLCGLESLTPNKLSIHMRRHNGEKPFKCDLCDMSFTVHYELKVHRRKHTGERPYQCTFCAKDFARPDKLRRHVYMHSVKR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00567692;
90% Identity: iTF_00570569;
80% Identity: -