Dsil011899.1
Basic Information
- Insect
- Drosophila silvestris
- Gene Symbol
- -
- Assembly
- GCA_035043445.1
- Location
- JAWNMZ010000151.1:19095218-19098691[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 8.5e-05 0.0056 17.0 5.0 1 23 175 198 175 198 0.97 2 15 0.0018 0.12 12.8 3.9 1 23 250 273 250 273 0.96 3 15 0.00083 0.055 13.9 2.8 1 23 339 362 339 362 0.94 4 15 0.0083 0.55 10.8 0.4 2 23 414 435 413 435 0.96 5 15 3.5 2.3e+02 2.5 3.0 1 20 548 567 548 569 0.85 6 15 0.02 1.3 9.6 0.6 1 23 578 600 578 600 0.94 7 15 0.00028 0.019 15.4 2.1 1 23 607 629 607 630 0.95 8 15 0.00045 0.029 14.8 1.4 2 23 638 659 637 659 0.96 9 15 0.014 0.91 10.1 0.1 2 21 686 705 685 709 0.88 10 15 0.5 33 5.1 0.6 1 23 747 770 747 770 0.91 11 15 3.5 2.3e+02 2.5 1.9 1 22 777 798 777 798 0.93 12 15 1.6e-05 0.0011 19.3 0.5 1 23 829 852 829 852 0.97 13 15 0.096 6.3 7.4 0.2 1 23 862 884 862 884 0.94 14 15 2.4e-05 0.0016 18.7 3.3 1 23 890 912 890 912 0.99 15 15 5.1e-05 0.0034 17.7 0.9 1 23 918 940 918 940 0.98
Sequence Information
- Coding Sequence
- ATGACAAGAACGTGTAGAATCTGTGGTGGCGCAGATGGACGCTTCTGGATCGAGACGCCAATTGATAAATACGCGGAGAAAACCTTCAATCACCTGCTGCTAGAGCTAACAAAACTCGAGGTCAATGTGGATCAAGCTGATAAGCTGCCGCCATGGATCTGCCGCAACTGTGCGCACAGATTAGAAAATGCCTACGACTTTGTGCTGCAGGCGAGGGAAACACACGAACTTTGGCTGCACAAGATGACAACAGAATCTCTTTCGGAGGACACCGAAACTGGGACGTTGGAGTGCCTGCGAGAGACACCCATTCAATTGCTGGAGATTGAGGGCGTCACAATTAAAATGGAGGAGGCAACCGAACCAGCCGTGCCACAAACAGATTCAGTCGGCTCGATTGATCCGCTAATTAAAAAGAGTCGAGAGGATGATGCCAGTAATAATGATGATAAcgctgatgatgacgatgatgatatTCCGCTAAAGCAGCGCCGGATTGCACGCACTAAACTGCCGACGATGCACAAGTGCAATAAGTGCGACAAGGCCTTCAAATATGTAACGAATCTCTTCAGGCACAAACAACGAGATCACACTCCAGAGCACAACCAAAGCAAAGAACAGGCAGCAGTGGAAAGTGAAAAGGCTGATCGCTTGAAACCCTTCTTAAACGATGTAATCAAGAGATCTATTGCAGCAACACACAGCAGCGAGGCAGACTTGGAAAGCGAATTGGCGGATAATTACTACAAGTGCGATCAATGCGACAAATCCTACAAGTACATAATGCTGCTGATCAGACACAAGCACAAGACGCACGCTTCCAACCAGTGTCCAGCAGAGCCCAGACCAATTAGAAGAAGCGGTTCGAGTGCAGAGCAAACTAATAGTAAACAAGGATCACCTCCTCAGCGCTCGAAACCGACCAGTACAGATTCGCTTGTGCACAGCATCATTAAAGAGATCAACTTACCCGATGAGGACGATGCAGACAGTTCCAGTGCCGACAATTACTACAAGTGCGACCAGTGCGACAAGTCGTACAAATACATTGTGAGTCTCatcaagcacaagcacaacgAGCACAAGGAATACAGGGATTCCGAGGAGGACGAAGATGGGGCAACGTCCTCCAGATATGCAGCAGATGCCACTGCTATGTCGAAGCCGTCGCGCATTGATCGTCGCGTCAAGGGCTTCGATTTGAATCGCTGCCGGCCAAACGGTTCCAAAGAGATTCAGTGCATGATCTGTCTGCGCAGATTCATCAAGTTGCGCGAGCTGCGTGATCACCTGAAAGCCCATCCTAAAGACTTTACATTCGATGCTCATGGCGAGCCGATTGAGCGCATTGCCGAGGGGTTCTATAAGACAGCCGTGGAATCCACAGTTGCGGGCCTGAAGCGACGCATCTTCAATGATCTCAAGGTTGGCATGCTCGGACGCTACTATTCCATAACAAATGAGGCACGGTACGAGATGAATCTGGACAGCTCGGACACAGACAGCGACGGCGAAGCGGATGTTGTGCAGCGGCATTCGTATGCCTGCGAACTGTGCGACTCCGCCGATGCCGTCTGGCCACGCAAATATCAATTGCACGAGCATCATCGGCAGCAGCACACCTGGCTGGAGGCGCCGCACGTCTGCCAGCGCTGTGATTTCCGCTTCCTGAGCGCGCAGCTGCTCGAGCATCATACGCACAAGTTGTGCCAGAACACCCTGAAGCGCTTCATGTGCGACAAATGTCCACAGCGCTTTTTTTGGCGACGCAATCTACGTGCGCATCTTGTCGAGCATAAAAACAAGCAGGAGACGTATCCGTGTGATCAGTGTTCGCGCAGCTTTCAGGACAAGAGCGCCGTAACGAAGCACAAGCTGATGCACCACGATGTCCACAACGAGCTGTTGCCCTGTCGCTGGTGCACGCGCACCTTCTACCGGCCGGCGCTGTTGCACAAGCATGTGCAGCGTCACGGCTTTAGTGGGGAGGATCTGCCGCTGGCAGAGACACTGCTGGCGGATGCCGCCAAGCCATCCGGTACGAAGACGATTGTCTGCAAACTTTGCGATATGCAGTTCATTAGCATTGGCGACCTGCGGCGACACAACTCGATGCAGGCGCACAGTGAGCAGGTGTCCAACTATATGATAAGCACCGAGGAGGGATTCGAGCTGCAGCTAGATGAAACGGACGAGAGTGATGAGGAGCCCACGAGTACTGCTGCCAGCCGATCTTATCGATGCGATCTGTGCGAGATGAGCTTCCTGCGAATGCGTGACATGAGCGAACATCAGTATTCACTGCACACCTTCGACAAGCTGCCACATTCCTGTGCGCATTGCATTTATAAGACAGTCGATAAGACCATGCTAGAGCACCATCTGAGCACACAGTGTCTTAACGAGGAGAAGAAATTCAGTGCTCTCTCATCATCTAGTCAGACGCCCGTTGCGGCGACAAAGCGGAGTAGACGTTTCCGATACCAGTGTCCACACTGCTGGCGCTCGTTTGTGGTGCAGCCCAGCCTGGACAAGCACATTCGGGACATGCATGTGGCGAAAAAGAATCCCGGCAAGAAGTATCTATGCTCGCTGTGCGGCTTGGAGTCGCTGACGCCAAATAAACTCAGCATACACATGCGGCGTCACAACGGCGAGAAGCCATTCAAATGTGATCTCTGCGACATGTCCTTCACCGTGCACTACGAGCTGAAGGTTCATCGCCGCAAGCATACCGGCGAGCGACCCTATCAGTGCACTTTCTGTGCAAAGGATTTCGCCCGGCCGGATAAGCTAAGACGGCATGTTTACATGCATAGCGTTAAGCGTTAA
- Protein Sequence
- MTRTCRICGGADGRFWIETPIDKYAEKTFNHLLLELTKLEVNVDQADKLPPWICRNCAHRLENAYDFVLQARETHELWLHKMTTESLSEDTETGTLECLRETPIQLLEIEGVTIKMEEATEPAVPQTDSVGSIDPLIKKSREDDASNNDDNADDDDDDIPLKQRRIARTKLPTMHKCNKCDKAFKYVTNLFRHKQRDHTPEHNQSKEQAAVESEKADRLKPFLNDVIKRSIAATHSSEADLESELADNYYKCDQCDKSYKYIMLLIRHKHKTHASNQCPAEPRPIRRSGSSAEQTNSKQGSPPQRSKPTSTDSLVHSIIKEINLPDEDDADSSSADNYYKCDQCDKSYKYIVSLIKHKHNEHKEYRDSEEDEDGATSSRYAADATAMSKPSRIDRRVKGFDLNRCRPNGSKEIQCMICLRRFIKLRELRDHLKAHPKDFTFDAHGEPIERIAEGFYKTAVESTVAGLKRRIFNDLKVGMLGRYYSITNEARYEMNLDSSDTDSDGEADVVQRHSYACELCDSADAVWPRKYQLHEHHRQQHTWLEAPHVCQRCDFRFLSAQLLEHHTHKLCQNTLKRFMCDKCPQRFFWRRNLRAHLVEHKNKQETYPCDQCSRSFQDKSAVTKHKLMHHDVHNELLPCRWCTRTFYRPALLHKHVQRHGFSGEDLPLAETLLADAAKPSGTKTIVCKLCDMQFISIGDLRRHNSMQAHSEQVSNYMISTEEGFELQLDETDESDEEPTSTAASRSYRCDLCEMSFLRMRDMSEHQYSLHTFDKLPHSCAHCIYKTVDKTMLEHHLSTQCLNEEKKFSALSSSSQTPVAATKRSRRFRYQCPHCWRSFVVQPSLDKHIRDMHVAKKNPGKKYLCSLCGLESLTPNKLSIHMRRHNGEKPFKCDLCDMSFTVHYELKVHRRKHTGERPYQCTFCAKDFARPDKLRRHVYMHSVKR
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00567692;
- 90% Identity
- iTF_00570569;
- 80% Identity
- -