Basic Information

Insect: Drosophila nigromelanica
Gene Symbol: -
Assembly: GCA_004149445.1
Location: SCDR01000672.1:73189-76338[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 2.8e-05 0.0034 18.3 4.7 1 23 171 194 171 194 0.97

2 16 0.0011 0.13 13.3 3.1 1 23 241 264 241 264 0.96

3 16 0.00086 0.1 13.6 2.4 1 23 331 354 331 354 0.93

4 16 0.0057 0.69 11.0 0.4 2 23 406 427 405 427 0.96

5 16 7.8 9.4e+02 1.2 1.1 1 19 540 558 540 561 0.72

6 16 0.0093 1.1 10.4 0.5 1 23 570 592 570 592 0.96

7 16 0.00024 0.029 15.4 2.1 1 23 599 621 599 622 0.95

8 16 0.00038 0.046 14.7 1.4 2 23 630 651 629 651 0.96

9 16 0.0016 0.19 12.8 0.1 3 22 679 698 677 701 0.89

10 16 0.016 1.9 9.6 1.0 1 23 737 760 737 760 0.96

11 16 1.2 1.5e+02 3.7 1.8 1 22 767 788 767 788 0.96

12 16 0.00096 0.11 13.5 1.0 1 23 797 820 797 820 0.97

13 16 1.4e-05 0.0016 19.3 0.5 1 23 839 862 839 862 0.97

14 16 0.032 3.9 8.7 0.2 1 23 872 894 872 894 0.94

15 16 2.1e-05 0.0025 18.7 3.3 1 23 900 922 900 922 0.99

16 16 2.9e-05 0.0035 18.3 1.2 1 23 928 950 928 950 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	2.8e-05	0.0034	18.3	4.7	1	23	171	194	171	194	0.97
2	16	0.0011	0.13	13.3	3.1	1	23	241	264	241	264	0.96
3	16	0.00086	0.1	13.6	2.4	1	23	331	354	331	354	0.93
4	16	0.0057	0.69	11.0	0.4	2	23	406	427	405	427	0.96
5	16	7.8	9.4e+02	1.2	1.1	1	19	540	558	540	561	0.72
6	16	0.0093	1.1	10.4	0.5	1	23	570	592	570	592	0.96
7	16	0.00024	0.029	15.4	2.1	1	23	599	621	599	622	0.95
8	16	0.00038	0.046	14.7	1.4	2	23	630	651	629	651	0.96
9	16	0.0016	0.19	12.8	0.1	3	22	679	698	677	701	0.89
10	16	0.016	1.9	9.6	1.0	1	23	737	760	737	760	0.96
11	16	1.2	1.5e+02	3.7	1.8	1	22	767	788	767	788	0.96
12	16	0.00096	0.11	13.5	1.0	1	23	797	820	797	820	0.97
13	16	1.4e-05	0.0016	19.3	0.5	1	23	839	862	839	862	0.97
14	16	0.032	3.9	8.7	0.2	1	23	872	894	872	894	0.94
15	16	2.1e-05	0.0025	18.7	3.3	1	23	900	922	900	922	0.99
16	16	2.9e-05	0.0035	18.3	1.2	1	23	928	950	928	950	0.98

Sequence Information

Coding Sequence: ATGACTAGAACGTGCCGAATCTGCGGCGGCGCAGACGGACGCTTCTGGATCGAGACGCCAGTCAATAAATACGCTGAGAAAACATACAATCAATTGCTGCTAGAGCTGACCAAGCTGCAGGTCGCCTTGGATCAAGCTGACAAGCTGCCGCCCTGGATTTGTCGAAGCTGCGCCCAGAGATTAGAGCATGCGTACGACTTTGTGCTGCAGGCGCGCGAAACTCACGAGCGCTGGTTGCAGAAGCTGGCAAAAGCAGCCCCGTCGGAGGACCAGGAAACAGGCACTTTGGAGTGTTTGCGAGAGACGCCCATACAACTGCTGGAAATAGAAGGCGTCACAATTAAAATGGAAGAGCCCTCAGAGCCGGTCATGGCCTCAACGGATCAAGGCAATCCAATTGATCCTCTCATCAAGAAAAGCATTGTGAACAATGAcagcgatgacgatgatgatgatgatgatgtacCGCTCAAGCAGCGTCGGAAAGCACACTGCAAGCTGCCAACGTTGCACAAGTGCAACAAATGCGGCAAAGCCTTCAAATATGTCACCAATCTCTTCAGGCACAAGCAGCGGGATCACAGCCCGACGAAGCTGCAAGAAACGGAGGAGAATCCAAAGACTGATCGCGCGGAGCCCTTTCTGCACAACCTGATAAAAAGCTCCATGACAACACGCGGCAGCGCGACAGAAGGGGACAACGACTCAACGGATGGTTACTATAAGTGCGATCAGTGCGACAAATCCTACAAGTACATAATGCTGCTCATCAAGCACAAGCACAAGGCGCACATCTCCAGCCAGTTGTCAGCGCAGCCCAAGCCTATCGGCAAAAGCAATTCCAGCACGGAGCCAACGGCTACCAAAACAAGAGGATCCCAGCGTCAGCGCTCGAAGGCACCGAGCACCGATTCCCTGGTGCACAGCATCATCAAAGAGATTAACATGCCCGATGAGGACGATGCCGGCAACTCCAGTGCGGACAATTACTACAAATGCGATCAGTGCGACAAATCCTACAAATACATCGTCAGTCTCATCAAGCACAACCACAGTGAGCACAAAGCGTACAAGGACTCTgatgaggacgaggacgaaGCCACCTCCTCGAGGTATGCAGCGGATGCAACTGCCATGACGAAGCCCTCGCGCATCGATCGACGGGTCAAAGGCTTCGATTTGCATCGGTGCAAGCCGAATGGCTCCAAGGAGATTCAATGCATGATCTGCCTGCGCAGATTTGTGAAACTGCGCGAGCTGCGCGACCATTTGAAGGCGCATCCCAAAGACTTTACCTTCGAGGCGCACGGCGAGCCGATTGAGCGTATTGCCGAGGGCTTCTACAAGACCGCCGTGGAGTCCACAGACGCTGGCCTCAAGCGGCGCATTTTCAATGATCTCAAGGTGGGCATGTTTGGGCGCTATTACTCCATTACCAATGAGGCGCGCTACGAGATGAATCTGGACAGCTCAGACACGGACAGCGACGGCGAAGCGGATGTTGTGGAGCGGCACAGTTACGCCTGCGAGCTGTGCGACTCGTCCGATGCCGTCTGGCCGCGCAAATATCAACTGCACGAACATCATCGACTGCAGCACACCTGGCTGGAGGCGCCGCATGTCTGCCAGCGCTGCGATTCACGTTTTCTGAGCGCCCAGCTGCTGGATCATCACACGCTCAAGCTATGCCAGAACACGCTTAAGCGTTTCATGTGCGACAAGTGTCCACAGCGCTTTTTCTGGCGGCGCAATCTGCGCGCGCATCTAGCGGAGCACAAAAACAAGCAAGAGACCTATCCGTGTGATCAGTGCTCGCGCAGCTTTCAGGACAAGAGCGCCGTGACCAAGCACAAGCTAATGCATCACGATGTCAGCAATGAGCTTCTGCCTTGCCGCTGGTGCACGCGCACCTTCTATCGGCCCGCGCTGCTGCACAAACATGTGCAGCGGCATGGCTTCAGCGGCGAGGATCTGCCCCTGGCCGAGACACTGCTGGCGGATGCTGCCAAGACATCCGGACCGAAGACAATCATTTGCAAGCTGTGCGACATGCAGTTCATTACCATTGCCGATCTGCGGCGGCACATCTCGATGCAGGGCCACGGCGAACAGGCCGCCAACTATATGATTAGCACCGAGGAGGgctttgagctgctgctggatgatACGGACGAGAGCGACGATGATGCTGCGGCCACTGCCGCATCCTATAGGTGTGCACTGTGCGATATGAATTTCCAGCGACGCCGCGAAATGAGCGAACATCAGTATTCGCTGCACACATTCGACAAGCTGCCGTATTCCTGTGAGCATTGCATTTTCAAGACAGTCGACAAGACCATGCTGGATCATCACCTGCGCACGCAATGCCGCAACCAGGAGAAGAAATTCAAGTGCTCCCGCTGTGGCTACAAGTTCATGTGGCGTGAAAATCTCGAACAGCACATGATCAGCCAGCATCCCAAGTCCTCTAATCAAGCGCCGGTGGCAATCAAGCGAAGCAGACGCTTCAGATATCAGTGTCCGCACTGCTGGCGCTCGTTTGTCGTGCAGCCCAGCCTGGACAAGCACATACGCGACATGCATGTGGCCAAAAAGAATCCCGGCAAGAAATATCTCTGCTCACTGTGCGGCCTGGAATCGCTGACGCCCAACAAGCTCAACATCCACATGCGCCGTCACAACGGCGAGAAGCCCTTCAAGTGCGATCTCTGCGACATGTCCTTTACCGTGCACTACGAGCTCAAGGTGCATCGGCGCAAGCACACTGGCGAGCGACCCTATCAGTGCACGTTCTGTGCCAAGAATTTCGCCAGGCCCGACAAGCTGAGGCGGCATGTTTATATGCACAGCGTTAAGCGTTAG
Protein Sequence: MTRTCRICGGADGRFWIETPVNKYAEKTYNQLLLELTKLQVALDQADKLPPWICRSCAQRLEHAYDFVLQARETHERWLQKLAKAAPSEDQETGTLECLRETPIQLLEIEGVTIKMEEPSEPVMASTDQGNPIDPLIKKSIVNNDSDDDDDDDDVPLKQRRKAHCKLPTLHKCNKCGKAFKYVTNLFRHKQRDHSPTKLQETEENPKTDRAEPFLHNLIKSSMTTRGSATEGDNDSTDGYYKCDQCDKSYKYIMLLIKHKHKAHISSQLSAQPKPIGKSNSSTEPTATKTRGSQRQRSKAPSTDSLVHSIIKEINMPDEDDAGNSSADNYYKCDQCDKSYKYIVSLIKHNHSEHKAYKDSDEDEDEATSSRYAADATAMTKPSRIDRRVKGFDLHRCKPNGSKEIQCMICLRRFVKLRELRDHLKAHPKDFTFEAHGEPIERIAEGFYKTAVESTDAGLKRRIFNDLKVGMFGRYYSITNEARYEMNLDSSDTDSDGEADVVERHSYACELCDSSDAVWPRKYQLHEHHRLQHTWLEAPHVCQRCDSRFLSAQLLDHHTLKLCQNTLKRFMCDKCPQRFFWRRNLRAHLAEHKNKQETYPCDQCSRSFQDKSAVTKHKLMHHDVSNELLPCRWCTRTFYRPALLHKHVQRHGFSGEDLPLAETLLADAAKTSGPKTIICKLCDMQFITIADLRRHISMQGHGEQAANYMISTEEGFELLLDDTDESDDDAAATAASYRCALCDMNFQRRREMSEHQYSLHTFDKLPYSCEHCIFKTVDKTMLDHHLRTQCRNQEKKFKCSRCGYKFMWRENLEQHMISQHPKSSNQAPVAIKRSRRFRYQCPHCWRSFVVQPSLDKHIRDMHVAKKNPGKKYLCSLCGLESLTPNKLNIHMRRHNGEKPFKCDLCDMSFTVHYELKVHRRKHTGERPYQCTFCAKNFARPDKLRRHVYMHSVKR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00567692;
90% Identity: iTF_00547508;
80% Identity: -