Basic Information

Insect: Drosophila neutralis
Gene Symbol: -
Assembly: GCA_035044385.1
Location: JAWNME010000532.1:4022528-4026032[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 7.6e-05 0.0052 17.3 5.8 1 23 175 198 175 198 0.97

2 15 0.002 0.14 12.8 3.9 1 23 246 269 246 269 0.96

3 15 0.00091 0.062 13.9 2.8 1 23 335 358 335 358 0.94

4 15 0.0074 0.51 11.0 0.4 2 23 410 431 409 431 0.96

5 15 0.022 1.5 9.6 0.6 1 23 574 596 574 596 0.94

6 15 0.00031 0.021 15.4 2.1 1 23 603 625 603 626 0.95

7 15 0.00049 0.034 14.7 1.4 2 23 634 655 633 655 0.96

8 15 0.015 1 10.0 0.1 2 21 682 701 681 705 0.88

9 15 0.13 8.6 7.2 0.9 1 23 744 767 744 767 0.95

10 15 4.7 3.2e+02 2.2 3.6 1 22 774 795 774 795 0.93

11 15 0.00062 0.042 14.4 1.2 1 23 804 827 804 827 0.98

12 15 1.8e-05 0.0012 19.3 0.5 1 23 848 871 848 871 0.97

13 15 0.11 7.3 7.4 0.2 1 23 881 903 881 903 0.94

14 15 2.7e-05 0.0018 18.7 3.3 1 23 909 931 909 931 0.99

15 15 5.7e-05 0.0039 17.7 0.9 1 23 937 959 937 959 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	7.6e-05	0.0052	17.3	5.8	1	23	175	198	175	198	0.97
2	15	0.002	0.14	12.8	3.9	1	23	246	269	246	269	0.96
3	15	0.00091	0.062	13.9	2.8	1	23	335	358	335	358	0.94
4	15	0.0074	0.51	11.0	0.4	2	23	410	431	409	431	0.96
5	15	0.022	1.5	9.6	0.6	1	23	574	596	574	596	0.94
6	15	0.00031	0.021	15.4	2.1	1	23	603	625	603	626	0.95
7	15	0.00049	0.034	14.7	1.4	2	23	634	655	633	655	0.96
8	15	0.015	1	10.0	0.1	2	21	682	701	681	705	0.88
9	15	0.13	8.6	7.2	0.9	1	23	744	767	744	767	0.95
10	15	4.7	3.2e+02	2.2	3.6	1	22	774	795	774	795	0.93
11	15	0.00062	0.042	14.4	1.2	1	23	804	827	804	827	0.98
12	15	1.8e-05	0.0012	19.3	0.5	1	23	848	871	848	871	0.97
13	15	0.11	7.3	7.4	0.2	1	23	881	903	881	903	0.94
14	15	2.7e-05	0.0018	18.7	3.3	1	23	909	931	909	931	0.99
15	15	5.7e-05	0.0039	17.7	0.9	1	23	937	959	937	959	0.98

Sequence Information

Coding Sequence: ATGACAAGAACGTGTAGAATCTGCGGTGGCGCAGATGGACGCTTCTGGATCGAGACGCCAGTTGATAAATACGCGGAGAAAACATTCAATCACTTGCTGCTGGAGCTAACACAACTCGAGGTCGCTGTGGATCAAGCTGATAAGCTGCCGCCATGGATTTGCCGCAACTGTGCGCACAGATTAGAAAGTGCCTACGACTTTGTGCTGCAGGCGAGGGAAACGCACGAGCTTTGGCTGCTCAAGCTGACAACAGCATCTCTATCGGAGGACACCGAAACTGGGACGTTGGAGTGCCTGCGAGAGACACCAATTCAATTGCTGGAGATTGAGGGCGTCACAATTAAAATGGAGGAGGCGACAGAACCAATCGTGCCCCAAACAGATTCAGTCAGCTCGATTGATCCGCTAATTAAAAAGAGCCGAGAGGATGATGCCAgcgatgatgataatgaaaCTGATGATTTTGATGATGATATGCCGCTCAAGCAGCGCCGgattgcacacacaaaactgcCGACGTTGCACAAGTGCAATAAGTGCAACAAGGCCTTTAAATATGTAACGAATCTCTTCAGGCATAAGCGACGAGAACACAGCCAAACCAAAGAAGACGCAGGAATGGAGAGTGAAAAGACTGATGGCGCGGAACCGTTCCTAAACGATGTAATCGAGAGCTCCATTGCAGCAACATGCAGCAGCGAGGCAGACTTGGAAAGCGAATCGGCGGATAACTACTACAAGTGCGATCAATGCGACAAATCCTACAAGTACATAATGCTTCTGATCAGGCACAAGCACAAAACGCACGCTTCTAGCCAGTGTCCAGCAGAGCCAAGACCAATTAGAAGAAGCGGTTCGAGTGCAGAGCAAACTAGTACTAAACAAGGATCGCCGCCTCAACGTTCGAAACCAACCAGCACAGATTCCCTGGTGCACAGCATCATCAAAGAGATCAACTTACCCGATGAGGACGATGCAGACAGTTCCAGTGTCGACAATTACTACAAGTGCGATCAGTGCGATaaatcatacaaatacattgtGAGTCTCAtcaagcacaagcacaacgAGCACAATGAGTACAGGGAGTCTGATGAGGACGAGGATGAGGCAACGTCCTCCAGAAATGCAACAGATGCCACTGCCATGTCGAAGCCCTCGCGCATTGATCGTCGCGTCAAGGGCTTCGATTTAAATCGTTGCCGGCCGAACGGTTCCAAGGAAATTCAGTGCATGATCTGTCTGCGCAGATTCGTCAAGTTGCGCGAGCTGCGCGATCACCTGAAAGCCCATCCCAAAGACTTAACATTCGATGGCCATGGCGAGCCGATTGAGCGCATTGCTGAAGGATTTTATAAAACAGCCGTGGAGTCCACAGTTGCGGGCCTGAAGCGACGCATCTTCCATGATCTCAGGGTGGGCATGCTCGGACGCTACTATTCCATAACGAATGAGGCACGCTACGAGATGAATCTGGACAGCTCGGACACGGACAGCGACGGCGAAGCGGATGTTGTGCAGCGGCATTCGTATGCCTGCGAACTGTGCGACTCCGCCGATGCCGTCTGGCCACGCAAGTATCAATTGCATGAGCATCATCGGCAGCAGCACACCTGGCTGGAGGCGCCGCACGTCTGCCAGCGCTGTGACTCCCGTTTCCTGAGCGCCCAGCTGCTTGAGCATCATACGCACAAGTTGTGCCAGAACACGCTGAAGCGCTTCATGTGCGACAAGTGTCCGCAGCGCTTCTTCTGGCGACGCAATCTACGTGCGCATCTTGTCGAGCACAAAAACAAGcAGGAGACATATCCGTGTGATCAGTGCTCGCGCAGTTTCCAGGACAAGAGCGCCGTAACGAAGCACAAGCTGATGCACCACGATGTGCACAACGAACTGTTGCCCTGCCGCTGGTGCACGCGCACCTTCTATCGGCCGGCGCTGTTGCACAAGCATGTCCAGCGTCACGGCTTTAGTGGGGAGGATCTGCCGCTGGCGGAGACACTGCTGGCGGATGCCGCCAAGCCATCTGGTACGAAGACGATTGTCTGCAAGCTGTGCGACATGCAGTTCATTAGCATTGGCGATCTGAGGCGGCACAACTCGATGCAGGCGCACGGTGAACAGGTGTCCAACTATATGATAAGCACCGAGGAGGGATTCGAGCTGCAGCTGGATGAAACGGACGAGAGTGATGGAGAGGAGCCGACGAGTACTGCTGCCAGCCGAACTTACCGGTGCGATCTGTGCGAGATGAGCTTCCTGCGAAGGCGCGACATGAGCGAACATCAGTATTCGCTGCACACCTTCGACAAGCTGCCACATTCATGTGAACATTGCATTTACAAGACAGTCGATAAGACCATGCTGGAGCACCATCTGCACACACAGTGTCTTAACGATGAGAAGAAATTCAAGTGCTCTCGTTGCGGCTACAAATTCATGTGGCGCGAAAATCTGGAGCAGCACATGAGCACTCTGCATCCTAAGTCATCATCTAGTCATACGGCCGTTGCGGCAACTAAGCGGAGCAGACGCTTCCGATACCAGTGTCCACACTGCTGGCGCTCGTTTGTGGTGCAGCCCAGCCTGGACAAACACATTCGGGACATGCATGTGGCGAAAAAGAATCCCGGCAAAAAGTATCTCTGCTCGCTGTGCGGCCTGGAGTCGCTGACCCCGAATAAGCTCAGCATACACATGCGGCGACACAACGGCGAGAAGCCATTCAAATGTGATCTCTGCGACATGTCCTTCACCGTGCACTACGAACTGAAGGTCCATCGTCGCAAGCATACCGGCGAGCGACCCTATCAGTGCACATTCTGTGCCAAGGATTTCGCCCGGCCGGATAAGCTACGACGGCATGTTTACATGCATAGCGTTAAGCGTTAA
Protein Sequence: MTRTCRICGGADGRFWIETPVDKYAEKTFNHLLLELTQLEVAVDQADKLPPWICRNCAHRLESAYDFVLQARETHELWLLKLTTASLSEDTETGTLECLRETPIQLLEIEGVTIKMEEATEPIVPQTDSVSSIDPLIKKSREDDASDDDNETDDFDDDMPLKQRRIAHTKLPTLHKCNKCNKAFKYVTNLFRHKRREHSQTKEDAGMESEKTDGAEPFLNDVIESSIAATCSSEADLESESADNYYKCDQCDKSYKYIMLLIRHKHKTHASSQCPAEPRPIRRSGSSAEQTSTKQGSPPQRSKPTSTDSLVHSIIKEINLPDEDDADSSSVDNYYKCDQCDKSYKYIVSLIKHKHNEHNEYRESDEDEDEATSSRNATDATAMSKPSRIDRRVKGFDLNRCRPNGSKEIQCMICLRRFVKLRELRDHLKAHPKDLTFDGHGEPIERIAEGFYKTAVESTVAGLKRRIFHDLRVGMLGRYYSITNEARYEMNLDSSDTDSDGEADVVQRHSYACELCDSADAVWPRKYQLHEHHRQQHTWLEAPHVCQRCDSRFLSAQLLEHHTHKLCQNTLKRFMCDKCPQRFFWRRNLRAHLVEHKNKQETYPCDQCSRSFQDKSAVTKHKLMHHDVHNELLPCRWCTRTFYRPALLHKHVQRHGFSGEDLPLAETLLADAAKPSGTKTIVCKLCDMQFISIGDLRRHNSMQAHGEQVSNYMISTEEGFELQLDETDESDGEEPTSTAASRTYRCDLCEMSFLRRRDMSEHQYSLHTFDKLPHSCEHCIYKTVDKTMLEHHLHTQCLNDEKKFKCSRCGYKFMWRENLEQHMSTLHPKSSSSHTAVAATKRSRRFRYQCPHCWRSFVVQPSLDKHIRDMHVAKKNPGKKYLCSLCGLESLTPNKLSIHMRRHNGEKPFKCDLCDMSFTVHYELKVHRRKHTGERPYQCTFCAKDFARPDKLRRHVYMHSVKR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00567692;
90% Identity: iTF_00570569;
80% Identity: -