Basic Information

Insect: Drosophila engyochracea
Gene Symbol: -
Assembly: GCA_035042385.1
Location: JAWNLK010000106.1:1051916-1055492[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 3.4e-05 0.0022 18.2 5.3 1 23 171 194 171 194 0.97

2 16 0.0018 0.12 12.8 3.9 1 23 246 269 246 269 0.96

3 16 0.00084 0.053 13.9 2.8 1 23 335 358 335 358 0.94

4 16 0.0084 0.53 10.7 0.4 2 23 410 431 409 431 0.96

5 16 3.5 2.2e+02 2.5 3.0 1 20 544 563 544 565 0.85

6 16 0.02 1.3 9.6 0.6 1 23 574 596 574 596 0.94

7 16 0.00028 0.018 15.4 2.1 1 23 603 625 603 626 0.95

8 16 0.00045 0.029 14.7 1.4 2 23 634 655 633 655 0.96

9 16 0.014 0.88 10.0 0.1 2 21 682 701 681 705 0.88

10 16 0.11 7.3 7.2 0.9 1 23 743 766 743 766 0.95

11 16 1.5 93 3.7 2.2 1 22 773 794 773 794 0.93

12 16 0.00057 0.036 14.4 1.2 1 23 803 826 803 826 0.98

13 16 1.6e-05 0.001 19.3 0.5 1 23 847 870 847 870 0.97

14 16 0.097 6.2 7.4 0.2 1 23 880 902 880 902 0.94

15 16 2.5e-05 0.0016 18.7 3.3 1 23 908 930 908 930 0.99

16 16 5.2e-05 0.0033 17.7 0.9 1 23 936 958 936 958 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	3.4e-05	0.0022	18.2	5.3	1	23	171	194	171	194	0.97
2	16	0.0018	0.12	12.8	3.9	1	23	246	269	246	269	0.96
3	16	0.00084	0.053	13.9	2.8	1	23	335	358	335	358	0.94
4	16	0.0084	0.53	10.7	0.4	2	23	410	431	409	431	0.96
5	16	3.5	2.2e+02	2.5	3.0	1	20	544	563	544	565	0.85
6	16	0.02	1.3	9.6	0.6	1	23	574	596	574	596	0.94
7	16	0.00028	0.018	15.4	2.1	1	23	603	625	603	626	0.95
8	16	0.00045	0.029	14.7	1.4	2	23	634	655	633	655	0.96
9	16	0.014	0.88	10.0	0.1	2	21	682	701	681	705	0.88
10	16	0.11	7.3	7.2	0.9	1	23	743	766	743	766	0.95
11	16	1.5	93	3.7	2.2	1	22	773	794	773	794	0.93
12	16	0.00057	0.036	14.4	1.2	1	23	803	826	803	826	0.98
13	16	1.6e-05	0.001	19.3	0.5	1	23	847	870	847	870	0.97
14	16	0.097	6.2	7.4	0.2	1	23	880	902	880	902	0.94
15	16	2.5e-05	0.0016	18.7	3.3	1	23	908	930	908	930	0.99
16	16	5.2e-05	0.0033	17.7	0.9	1	23	936	958	936	958	0.98

Sequence Information

Coding Sequence: ATGACGAGAACGTGTAGAATCTGCGGTGGCGCAGATGGACGCTTCTGGATCGAGACGCCAATTGAGAAATACGCGGAGAAAACATTCAATCACCTGCTGCTGGAGCTAACAAAACTCGAGGTCACTGTGGATCAAGCTGATAAGCTACCGCCATGGATCTGCCGCAACTGTGCGCACAGATTAGAAAATGCCTACGACTTTGTGCTGCAAGCGAAGGAAACTCACGAGCTTTGGCTGCACAAGATGACAACAGAATCTCTATCGGAGGATACCGAAACTGGGACGTTGGAGTGCCTGCGAGAGACACCCATTCAATTGCTGGAGATTGAGGGCGTCACAATTAAAATGGAGGAGGCAACCGAACCAGCCGTGCCACAAACAGATTCAGTCGGCTCGATTGATCCGCTAATTAAAAAGAGCCGAGAGGATGATGCCAgcaataatgatgatgacgatgatgatatACCGCTCAAGCAGCGCCGGATTGCAAGCACAAAACTGCCAACGATGCACAAGTGCAATAAGTGCGACAAAGCCTTCAAATATGTAACGAATCTCTTCAGGCACAAGCGACGAGATCACTCTCCAGAGCACAGCCAAACCAAAGAACAGACAGCAGTGGAAAGTGAAAAGACTGATAGCATGAAACCGCTCTTAAACGATGTAATCAAGAGCTCCATTGTAACAACACACAGCAGCGAGGCAGACTTGGAAGGCGAATTGGCGGATAATTACTACAAGTGCGATCAATGCGACAAATCCTACAAGTACATAATGCTGCTGATCAGACACAAGCACAAAACGCACGCTTCCAGCCAGTGTCCAGCAGAGCCCAGACCAATTAGAAGAAGCGGTTCGAGTGCAGAGCAAACTAATACTAAACAAGGTTCACCGCCTCAGCGCTCGAAACCGACCAACACAGATTCGCTTGTGCACAGTATCATCAAAGAGATCAACTTACCCGATGAGGACGATGCAGACAGTTCCAGTGCCGACAATTACTACAAGTGCGACCAGTGTGACAAGTCGTACAAATACATTGTGAGTCTCATCAAGCACAAACACAACGAGCACAAGGAATACAGGGATTCCGATGAGGATGAAGATGGGGCAACGTCCTCTAGATATGCAGCAGATGCCACTACTATGTCAAAGCCGTCGCGCATTGATCGTCGCGTCAAAGGCTTCGATTTGAATCGCTGCCGGCCAAACGGTTCCAAAGAGATTCAGTGCATGATCTGTCTGCGCAGATTCATCAAGTTGCGCGAGCTGCGTGATCACCTGAAAGCCCATCCTAAAGATTTTACATTCGATGCTCATGGCGAGCCGATTGAGCGCATTGCCGAGGGATTCTATAAGACAGCCGTGGAATCCACAGTTGCAGGTCTCAAGCGACGGATCTTCAACGATCTCAAGGTTGGTATGCTCGGACGCTACTATTCCATAACAAATGAGGCACGGTACGAGATGAATCTGGACAGCTCGGACACGGACAGTGACGGCGAAGCGGATGTTGTGCAGCGGCATTCGTATGCCTGCGAATTGTGCGACTCCGCCGATGCCGTCTGGCCACGCAAATATCAATTGCACGAGCATCATCGGCAGCAGCACACCTGGCTGGAGGCGCCGCACGTCTGCCAGCGCTGTGACTTCCGCTTCCTGAGCGCGCAGCTACTCGAGCATCACACGCACAAGTTGTGCCAGAACACCCTGAAGCGCTTCATGTGCGACAAGTGTCCACAGCGCTTCTTTTGGCGACGCAATCTACGTGCGCATCTTGTCGAGCACAAAAACAAGCAGGAGACGTATCCGTGTGATCAGTGCTCACGCAGCTTTCAGGACAAGAGCGCCGTGACGAAGCACAAGCTGATGCACCACGATGTCCACAATGAGCTGTTGCCCTGTCGCTGGTGCACGCGCACCTTCTACCGGCCGGCGCTGTTGCACAAGCATGTGCAGCGTCATGGCTTTAGTGGGGAGGATCTGCCACTTGCAGAGACACTGCTGGCGGATGCCGCCAAGCCATCCGGTACAAAGACGATTGTCTGCAAACTTTGCGATATGCAGTTCATTAGCATTGGCGACCTGCGGCGACACAACTCGATGCAGGCGCACAGTGAGCAGGTGTCCAACTATATGATAAGCACCGAGGAGGGATTCGAGCTGCAGCTGGATGAAACGGACGAGAGTGATGAGGAGCCCACAAGTACTGCTGCCAGCCGATCTTATCGATGCGATCTGTGCGAGATGAGTTTCCTGCGAAGGCGCGACATGAGCGAACATCAGTATTCGCTGCACACCTTCGATAAGCTGCCACATTCTTGTGAGCATTGCATTTACAAGACAGTCGATAAGACTATGCTAGAGCACCACCTAAGCACACAGTGTCTTAACGAGGAGAAAAAATTCAAGTGCTCTCGTTGCGGCTACAAATTCATGTGGCGCGAAAATCTGGAGCAGCACATGAGCACTCTGCATCCCAAGTCATCATCTAGTCAGACACAGGTTGCGGCGACAAAGCGGAGTAGACGTTTCCGATACCAGTGTCCACACTGCTGGCGCTCGTTTGTGGTGCAGCCCAGCCTGGACAAGCACATTCGGGACATGCATGTGGCGAAAAAGAATCCCGGCAAGAAGTATCTATGCTCGTTGTGCGGCCTGGAGTCGCTGACCCCAAATAAGCTCAGCATACACATGCGGCGCCACAACGGCGAGAAGCCATTCAAATGTGATCTCTGCGACATGTCCTTCACCGTGCACTACGAGCTGAAGGTTCATCGCCGCAAGCATACCGGCGAGCGACCCTATCAGTGCACATTCTGTGCCAAGGATTTCGCCCGGCCGGATAAGCTAAGACGGCATGTTTACATGCATAGCGTTAAGCGTTAA
Protein Sequence: MTRTCRICGGADGRFWIETPIEKYAEKTFNHLLLELTKLEVTVDQADKLPPWICRNCAHRLENAYDFVLQAKETHELWLHKMTTESLSEDTETGTLECLRETPIQLLEIEGVTIKMEEATEPAVPQTDSVGSIDPLIKKSREDDASNNDDDDDDIPLKQRRIASTKLPTMHKCNKCDKAFKYVTNLFRHKRRDHSPEHSQTKEQTAVESEKTDSMKPLLNDVIKSSIVTTHSSEADLEGELADNYYKCDQCDKSYKYIMLLIRHKHKTHASSQCPAEPRPIRRSGSSAEQTNTKQGSPPQRSKPTNTDSLVHSIIKEINLPDEDDADSSSADNYYKCDQCDKSYKYIVSLIKHKHNEHKEYRDSDEDEDGATSSRYAADATTMSKPSRIDRRVKGFDLNRCRPNGSKEIQCMICLRRFIKLRELRDHLKAHPKDFTFDAHGEPIERIAEGFYKTAVESTVAGLKRRIFNDLKVGMLGRYYSITNEARYEMNLDSSDTDSDGEADVVQRHSYACELCDSADAVWPRKYQLHEHHRQQHTWLEAPHVCQRCDFRFLSAQLLEHHTHKLCQNTLKRFMCDKCPQRFFWRRNLRAHLVEHKNKQETYPCDQCSRSFQDKSAVTKHKLMHHDVHNELLPCRWCTRTFYRPALLHKHVQRHGFSGEDLPLAETLLADAAKPSGTKTIVCKLCDMQFISIGDLRRHNSMQAHSEQVSNYMISTEEGFELQLDETDESDEEPTSTAASRSYRCDLCEMSFLRRRDMSEHQYSLHTFDKLPHSCEHCIYKTVDKTMLEHHLSTQCLNEEKKFKCSRCGYKFMWRENLEQHMSTLHPKSSSSQTQVAATKRSRRFRYQCPHCWRSFVVQPSLDKHIRDMHVAKKNPGKKYLCSLCGLESLTPNKLSIHMRRHNGEKPFKCDLCDMSFTVHYELKVHRRKHTGERPYQCTFCAKDFARPDKLRRHVYMHSVKR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00567692;
90% Identity: iTF_00570569;
80% Identity: -