Basic Information

Insect: Drosophila kokeensis
Gene Symbol: -
Assembly: GCA_035042145.1
Location: JAWNLT010000346.1:10436565-10440098[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 9.3e-06 0.0006 20.1 6.2 1 23 171 194 171 194 0.98

2 16 0.0019 0.12 12.8 3.9 1 23 242 265 242 265 0.96

3 16 0.00087 0.056 13.9 2.8 1 23 331 354 331 354 0.94

4 16 0.023 1.5 9.4 0.3 2 23 406 427 405 427 0.95

5 16 9.6 6.2e+02 1.2 2.5 1 20 540 559 540 561 0.85

6 16 0.021 1.3 9.6 0.6 1 23 570 592 570 592 0.94

7 16 0.0003 0.019 15.4 2.1 1 23 599 621 599 622 0.95

8 16 0.00047 0.03 14.7 1.4 2 23 630 651 629 651 0.96

9 16 0.016 1.1 9.9 0.1 2 20 678 696 677 701 0.89

10 16 0.14 8.9 7.0 1.0 1 23 740 763 740 763 0.95

11 16 0.41 26 5.5 2.6 1 22 770 791 770 791 0.96

12 16 0.00059 0.038 14.4 1.2 1 23 800 823 800 823 0.98

13 16 1.7e-05 0.0011 19.3 0.5 1 23 844 867 844 867 0.97

14 16 0.1 6.5 7.4 0.2 1 23 877 899 877 899 0.94

15 16 2.6e-05 0.0016 18.7 3.3 1 23 905 927 905 927 0.99

16 16 5.4e-05 0.0035 17.7 0.9 1 23 933 955 933 955 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	9.3e-06	0.0006	20.1	6.2	1	23	171	194	171	194	0.98
2	16	0.0019	0.12	12.8	3.9	1	23	242	265	242	265	0.96
3	16	0.00087	0.056	13.9	2.8	1	23	331	354	331	354	0.94
4	16	0.023	1.5	9.4	0.3	2	23	406	427	405	427	0.95
5	16	9.6	6.2e+02	1.2	2.5	1	20	540	559	540	561	0.85
6	16	0.021	1.3	9.6	0.6	1	23	570	592	570	592	0.94
7	16	0.0003	0.019	15.4	2.1	1	23	599	621	599	622	0.95
8	16	0.00047	0.03	14.7	1.4	2	23	630	651	629	651	0.96
9	16	0.016	1.1	9.9	0.1	2	20	678	696	677	701	0.89
10	16	0.14	8.9	7.0	1.0	1	23	740	763	740	763	0.95
11	16	0.41	26	5.5	2.6	1	22	770	791	770	791	0.96
12	16	0.00059	0.038	14.4	1.2	1	23	800	823	800	823	0.98
13	16	1.7e-05	0.0011	19.3	0.5	1	23	844	867	844	867	0.97
14	16	0.1	6.5	7.4	0.2	1	23	877	899	877	899	0.94
15	16	2.6e-05	0.0016	18.7	3.3	1	23	905	927	905	927	0.99
16	16	5.4e-05	0.0035	17.7	0.9	1	23	933	955	933	955	0.98

Sequence Information

Coding Sequence: ATGACAAGAACGTGTAGAATCTGCGGTGGCGCAGATGGACTCTTCTGGATCGAGACGCCAGTTGATAAATACGCGAAGAAAACATTCAATCACTTGCTGCTGGAGCTAACACAACTCGAGGTCGCTGTGGGTCATGCTGATAAGCTGCCGCCATGGATTTGCCGCAACTGTGCGCACAGATTAGAAAGTGCCTACGACTTTGTGCTGCAGGCGAGGGAAACGCACGAGCTTTGGCTGCTCAAACTGACAAGAGAATCTCTATCGGAGGACACCGAAACTGGGACGTTGGAGTGCCTGCGTGAGACACCAATTCAATTGCTGGAGATTGAGGGCGTCACAATTAAAATGGAGGAAGCGACAGAACCAATCGTGCCCCAAACAGATTCAGTCAGCTCGATTGATCCGCTAATTAAAAAGAGCCGAGAGGATGATGccagcgatgatgatgatgatgatgatgatatgcCGCTCAAGCAGCGCCGgattgcacacacaaaactgcCGACGTTGCACAAGTGCAATAAGTGCAACAAGGCCTTCAAATATGTAACGAATCTCTTCAGGCACATGCGACGAAAACACAGCCAAACCAAAGAAGAGGCAGGAATGGCGAGTGAAAAGACTGATGGCGCGGAACCGTTCATAAACGATGTAATCGAGAGCTCCATTGCAGCAACACGCAGCAGCGAGGCAGACTTGGAAAGCGAATCGTCGGATAACTACTATAAGTGCGATCAATGCGACAAATCCTACAAGTACATAATGCTGCTGATCAGGCACAAGCACAAAACGCACGCTTCTAGCCAGtgtccagcagagcccacccCAATGAGAAGAAGCGGTTCGAGTGCAGAGCAAACTAATACTAAACAAGGATCGCCGCCTCAGCGTTCGAAACCGACCAGCACAGATTCCCTGGTGCACAGCATCATCAAAGAGATCAATTTGCCCGATGAGGACGATGCAGACAGTTCCAGTGTCGACAATTACTACAAGTGCGATCAGTGCGATAAATCGTACAAATACATTGTGAGTCTCatcaagcacaagcacaacgAGCACAATGAGTACAGGGATTCTgatgaggacgaggatgaggcAACGTCCTCCAGAAATGCAACAGATGCCATTGCCATGTCGAAGCCCTCGCGCATTGATCGTCGCGTCAAGGGCTTCGATTTAAATCGCTGCCGGCCGAACGGTTCCAAGGAGATTCAGTGCATGATCTGTCTGCGCAGATTCGTCAAGTTGCGCGAGCTGCGCGATCACCTGACAGCCCATCCCAAAGACTTAACATTCGATGCCCATGGCGAGCCGATTGAGCGCATTGCCGAAGGATTTTATAAAACAGCCGTGGAGTCCACAGTTGCGGGCCTGAAGCGACGCATCTTCCACGATCTCAGGGTGGGCATGCTCGGACGCTACTATTCCATAACAAATGAGGCACGCTACGAGATGAATCTGGACAGCTCGGACACGGACAGCGACGGCGAAGCGGATGTTGTGCAGCGGCATTCGTATGCCTGCGAACTGTGCGACTCCGCCGATGCCGTCTGGCCACGCAAGTATCAATTGCACGAGCATCATCGGCAGCAGCACACCTGGCTGGAGGCGCCGCACGTCTGCCAGCGCTGTGACTCCCGTTTCCTGAGCGCCCAGCTGCTTGAGCATCATACGCACAAGTTGTGCCAGAACACCCTTAAGCGCTTCATGTGTGACAAGTGTCCGCAGCGCTTCTTTTGGCGACGTAATCTACGTGCGCATCTTGTCGAGCACAAAAACAAGcAGGAGACATATCCGTGTGATCAGTGCTCCCGCAGTTTCCAGGACAAGAGCGCCGTCACGAAGCACAAGCTGATGCACCACGATGTGCACAACGAACTGTTGCCCTGCCGCTGGTGCACGCGCACCTTCTATCGGCCGGCGCTGTTGCACAAGCATGTGCAGCGTCACGGCTTTAGTGGGGAGGATCTGCCACTGGCGGAGACACTGTTGGCGGATGCCGCCAAGCCGTCCGGTACGAAGACTATAGTCTGCAAGCTATGCGACATGCAGTTCATTAGCATTGGCGATCTGAGGCGGCACAACTCAATACAGGCGCACGGTGAACAGGTGTCCAACTATATGATAAGCACTGAGGAGGGATTCGAGCTGCAGCTGGACGAAACGGACGAGAGTGATGGAGAGGAGCCGACGAGTACTGCTGCCAGCCGAACTTATCGGTGCGATCTGTGCGAGATGACCTTCCTGCGAAGGCGCGACATGAGCGAACATCAGTATTCGCTGCATACCTTCGACAAGCTGCCACATTCCTGTGAACATTGCATTTACAAGACAGTCGATAAGACCATGCTGGAGCACCATCTGCGTACACAGTGTCTTAACGATGAGAAGAAATTCAAGTGCTCTCGTTGCGGCTACAAATTCATGTGGCGCGAAAATCTGGAGCAGCACATGAGCACTCTGCATCCTAAGTCATCATCTAGTCAAACGGCCGTGGCGGCAACTAAGCGGAGCAGACGCTTCCGATACCAGTGTCCACACTGCTGGCGCTCGTTTGTGGTGCAGCCCAGCCTGGACAAACACATTCGGGACATGCATGTGGCGAAAAAGAATCCCGGCAAGAAGTATCTCTGCTCGCTGTGCGGCCTGGAGTCGCTGACCCCGAATAAGCTCAGCATTCACATGCGGCGACACAACGGTGAGAAGCCATTCAAATGTGATCTCTGCGACATGTCCTTCACCGTGCACTACGAACTGAAGGTCCATCGCCGCAAGCATACTGGCGAGCGACCCTATCAGTGCACATTCTGTGCCAAGGATTTCGCCCGGCCGGATAAGCTACGACGGCATGTTTACATGCATAGCGTTAAGCGTTAA
Protein Sequence: MTRTCRICGGADGLFWIETPVDKYAKKTFNHLLLELTQLEVAVGHADKLPPWICRNCAHRLESAYDFVLQARETHELWLLKLTRESLSEDTETGTLECLRETPIQLLEIEGVTIKMEEATEPIVPQTDSVSSIDPLIKKSREDDASDDDDDDDDMPLKQRRIAHTKLPTLHKCNKCNKAFKYVTNLFRHMRRKHSQTKEEAGMASEKTDGAEPFINDVIESSIAATRSSEADLESESSDNYYKCDQCDKSYKYIMLLIRHKHKTHASSQCPAEPTPMRRSGSSAEQTNTKQGSPPQRSKPTSTDSLVHSIIKEINLPDEDDADSSSVDNYYKCDQCDKSYKYIVSLIKHKHNEHNEYRDSDEDEDEATSSRNATDAIAMSKPSRIDRRVKGFDLNRCRPNGSKEIQCMICLRRFVKLRELRDHLTAHPKDLTFDAHGEPIERIAEGFYKTAVESTVAGLKRRIFHDLRVGMLGRYYSITNEARYEMNLDSSDTDSDGEADVVQRHSYACELCDSADAVWPRKYQLHEHHRQQHTWLEAPHVCQRCDSRFLSAQLLEHHTHKLCQNTLKRFMCDKCPQRFFWRRNLRAHLVEHKNKQETYPCDQCSRSFQDKSAVTKHKLMHHDVHNELLPCRWCTRTFYRPALLHKHVQRHGFSGEDLPLAETLLADAAKPSGTKTIVCKLCDMQFISIGDLRRHNSIQAHGEQVSNYMISTEEGFELQLDETDESDGEEPTSTAASRTYRCDLCEMTFLRRRDMSEHQYSLHTFDKLPHSCEHCIYKTVDKTMLEHHLRTQCLNDEKKFKCSRCGYKFMWRENLEQHMSTLHPKSSSSQTAVAATKRSRRFRYQCPHCWRSFVVQPSLDKHIRDMHVAKKNPGKKYLCSLCGLESLTPNKLSIHMRRHNGEKPFKCDLCDMSFTVHYELKVHRRKHTGERPYQCTFCAKDFARPDKLRRHVYMHSVKR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00567692;
90% Identity: iTF_00570569;
80% Identity: -