Dmet002988.1
Basic Information
- Insect
- Drosophila mettleri
- Gene Symbol
- -
- Assembly
- GCA_035047625.1
- Location
- JAWNPI010000035.1:10040661-10043771[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 17 0.00029 0.02 15.3 6.2 1 23 170 193 170 193 0.97 2 17 0.0012 0.083 13.3 3.1 1 23 231 254 231 254 0.96 3 17 0.00079 0.054 13.9 2.8 1 23 309 332 309 332 0.94 4 17 0.0034 0.23 12.0 0.7 2 23 384 405 383 405 0.97 5 17 0.52 35 5.1 1.0 3 23 487 511 485 511 0.78 6 17 7 4.7e+02 1.5 2.2 1 19 518 536 518 539 0.72 7 17 0.024 1.7 9.3 0.6 1 23 548 570 548 570 0.93 8 17 0.00027 0.018 15.4 2.1 1 23 577 599 577 600 0.95 9 17 0.00043 0.029 14.8 1.4 2 23 608 629 607 629 0.96 10 17 0.00086 0.059 13.8 0.1 2 23 656 679 655 679 0.89 11 17 0.0048 0.33 11.5 1.0 1 23 715 738 715 738 0.96 12 17 0.065 4.4 7.9 1.0 1 22 745 766 745 766 0.97 13 17 0.064 4.3 7.9 1.9 1 23 775 798 775 798 0.95 14 17 1.5e-05 0.001 19.3 0.5 1 23 817 840 817 840 0.97 15 17 0.036 2.5 8.7 0.2 1 23 850 872 850 872 0.94 16 17 2.3e-05 0.0016 18.8 3.3 1 23 878 900 878 900 0.99 17 17 4.9e-05 0.0033 17.7 0.9 1 23 906 928 906 928 0.98
Sequence Information
- Coding Sequence
- ATGACTAGAACGTGCCGAATCTGTGGCGGCGGAGATGGGCGTTATTGGATCGAGAGCCCATTTACTAAATACGCAGATAAAACGTACAATCAACTACTGCTGGAGTTAACAAGGCTTGAGatTGAGTTGAATCAAGCCGACAAGTTTCCGGCCTGGATTTGTCGTAGCTGCTCTCAGAGATTGGAGAATGCATACGATTTTGTACAGCAAGCGCGCAAAACTCATGAGCTATGGCTGCAAAAGATCTCAAAAGAAGCTCTCTCCGGGGACGCAGAAACAGCCACTTTTGAGTGTTTGCGCGAGACCCCAATACAACTGATAGATATAGAAggtataacaattaaaatggAAGAGCCCACAGAGCCTGTTATGACATCCGCCGATCCAAGCAACACAATTGATCCTTTGATTAAGAAGAGCAATATGGATGAAGGCAGCAccgatgatgacgacgatgatgtGCCTCTAAAACAACGCCGGGCAGCGCAAGCAAAACTCGCCGTTCTGCACAAGtgcaataaatgcaataaagcTTTCAGATATGTTACTAATCTCTTCAGGCACAAGCAACGATATCATAGTCAATCTAAGCCACAGGATGCCCAGGAGAAAATTAATCGAGCGGAACTATCATCCAGCTCTATTGAGGCTAAAAGCTGCGCcgTGGATAATGAATCAGTCGATAGCTACTACAAATGCGATCAATGTGACAAATCTTACAAGTACATAATGCTGCTAATCAAACATAAGCACAAGGCGCATGTTTCCAGCCAGATATCAGCGCAGCCTCCATTTACAGATCCAGCAAAAGAATCCCAACGGCGCTCGAAACCGTCTAGCACGGATTCCCTTGTGCACAGCATCATCAAAGAGATtaaTATTCCCGATGAGGATGATGCAGATAACTGTAGTGCAGACAACTATTACAAATGTGATCAGTGCGACAAATCCTACAAGTACATTGTTAGTCTCatcaagcacaagcacaacgAACACAAGGCGTACAAGGattctgatgatgatgaagacgAAGCCACATCATCTAGATACGCAACGGACACATCGGCGATAACGAAGCCCTCACGCATCGATCGTCGCGTCAAAGGCTTCGACTTGCATCGCTGCAAGCCGAATGGCTCCAAGGAAATTCAGTGCATGATCTGTCTGCGTAGATTTATTAAACTACGCGAGCTGCGCGACCATTTAAAGTCTCATCCTAAGGACTTCGAATTCGAGGCTCATGGCGAGCCGATTGAGCGGATTGCAGAGGGCTTTTATAAGACTGCCGTAGAGTCCACAGCTGCCGGATTAAAGCGGCGCATTTTCAATGATCTCAAATTGGGCATGTACGGTCGCTATTACTCAATAACGAACGAGGCGCGATATGAAATGAATCTCGACAGCTCCGACACGGACAGCGATGGGGAGGCGGATGTTGTTGAGCGCCACAGCTATGCATGTGAGCTATGTGCGTCGCCCAAGGCCGTGTTCCCACGCAAATATCAATTGCACGAGCATCATCGACAGGAGCATACCTGGCTTGAGGCCCCTCATGTCTGTCGGCGTTGCGATGCACGATTTCTGAGCTCCGAACTGCTGGATCATCATACGCACAAATTGTGTCAAAACACGCTCAAGCGGTTCATGTGCGATAAGTGTCCACAGCGTTTTTTCTGGCGACGCAATTTGCGCGCGCATCTTGTGGATCACAAAAATAAGCAAGAGACATACCCTTGCGATCAGTGCTCTCGCAGCTTTCAGGACAAGAGCGCCGTGACGAAGCACAAGCTAATGCACCACGACGGCAGCAATGAATTGTTACCCTGTCGTTGGTGCACACGCACTTTCTATCGACCTGCGCTTTTGCACAAGCATGTGCAGCGCCATGGGTTCAGTGGTGAGGATCTGCCATTGGCAGAGACACTGCTGGCGGATGCTGCCAAGACTTCCGGCCCAAAGACCATAATGTGCAAGCTATGCGATATGCAATTCATTAGCATTGCAGATCTGAAACGGCACATGTCGATGCAGGCACACCCTGTAGAGACGTCCAACTATATGATAAGCACTGAAGAGGGCTTTGAGCTGCTGTTGGATGAGACAGATGAAAGCGACGATGAGGCTGGAAGCTCTAGTAGAACTTATCGATGTGCTCTATGTGACATGAGCTTTCAGCGACGCCGCGAAATGAGCGAACATCAGTATTCTCTACACACCTTTGACAAGTTGCCCTATTCCTGTGAGCATTGCATTTTTAAGACTGTCGACAAGACCATGCTGGAGCGGCATTTGCGAACGCAGTGCCTTAACCAGGAAAAGAAATTTAAGTGCTCTCGCTGTGGCTACAAATTCATGTGGCACGAAAATCTGGAGCTGCACGTATCGAGCCAACATTCCAAGTCGTCCAATCAGGCACCTGTTACAACAAAGCGCAGCAGACGTTTTAGATATCAGTGTCCACATTGCTGGCGCTCTTTTGTTGTACAGCCTAGTCTGGACAAGCATATAAGAGACATGCATGTCGCCAAAAAGAATCCGGGCAAGAAATATCTCTGCTCACTATGCGGTCTGGAGTCTCTGACCCCCAACAAGCTGAACATACATATGCGCCGGCACAACGGCGAGAAACCATTCAAATGCGATCTCTGCGACATGTCCTTTACCGTGCACTACGAACTGAAGGTGCATCGACGCAAGCACACAGGCGAGCGACCCTATCAGTGCACGTTCTGTGCCAAGGATTTCGCCAGGCCAGATAAACTGAGGCGGCATGTCTACATGCATAGCGTTAAgcgttaa
- Protein Sequence
- MTRTCRICGGGDGRYWIESPFTKYADKTYNQLLLELTRLEIELNQADKFPAWICRSCSQRLENAYDFVQQARKTHELWLQKISKEALSGDAETATFECLRETPIQLIDIEGITIKMEEPTEPVMTSADPSNTIDPLIKKSNMDEGSTDDDDDDVPLKQRRAAQAKLAVLHKCNKCNKAFRYVTNLFRHKQRYHSQSKPQDAQEKINRAELSSSSIEAKSCAVDNESVDSYYKCDQCDKSYKYIMLLIKHKHKAHVSSQISAQPPFTDPAKESQRRSKPSSTDSLVHSIIKEINIPDEDDADNCSADNYYKCDQCDKSYKYIVSLIKHKHNEHKAYKDSDDDEDEATSSRYATDTSAITKPSRIDRRVKGFDLHRCKPNGSKEIQCMICLRRFIKLRELRDHLKSHPKDFEFEAHGEPIERIAEGFYKTAVESTAAGLKRRIFNDLKLGMYGRYYSITNEARYEMNLDSSDTDSDGEADVVERHSYACELCASPKAVFPRKYQLHEHHRQEHTWLEAPHVCRRCDARFLSSELLDHHTHKLCQNTLKRFMCDKCPQRFFWRRNLRAHLVDHKNKQETYPCDQCSRSFQDKSAVTKHKLMHHDGSNELLPCRWCTRTFYRPALLHKHVQRHGFSGEDLPLAETLLADAAKTSGPKTIMCKLCDMQFISIADLKRHMSMQAHPVETSNYMISTEEGFELLLDETDESDDEAGSSSRTYRCALCDMSFQRRREMSEHQYSLHTFDKLPYSCEHCIFKTVDKTMLERHLRTQCLNQEKKFKCSRCGYKFMWHENLELHVSSQHSKSSNQAPVTTKRSRRFRYQCPHCWRSFVVQPSLDKHIRDMHVAKKNPGKKYLCSLCGLESLTPNKLNIHMRRHNGEKPFKCDLCDMSFTVHYELKVHRRKHTGERPYQCTFCAKDFARPDKLRRHVYMHSVKR
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00567692;
- 90% Identity
- -
- 80% Identity
- -