Basic Information

Insect: Drosophila virilis
Gene Symbol: -
Assembly: GCA_007989325.2
Location: CM017605.2:21216644-21220442[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 6e-05 0.0036 17.4 5.9 1 23 171 194 171 194 0.97

2 16 6.4e-05 0.0038 17.3 1.7 1 23 243 266 243 266 0.98

3 16 0.00076 0.045 13.9 2.8 1 23 332 355 332 355 0.94

4 16 0.0076 0.45 10.7 0.4 2 23 407 428 406 428 0.96

5 16 9.3 5.5e+02 1.0 1.3 1 20 541 560 541 562 0.82

6 16 0.018 1.1 9.6 0.6 1 23 571 593 571 593 0.94

7 16 0.00026 0.015 15.4 2.1 1 23 600 622 600 623 0.95

8 16 0.00041 0.024 14.7 1.4 2 23 631 652 630 652 0.96

9 16 0.011 0.66 10.2 0.1 3 22 680 699 678 702 0.88

10 16 0.011 0.67 10.2 1.1 1 23 738 761 738 761 0.96

11 16 0.016 0.92 9.8 0.7 1 22 768 789 768 789 0.97

12 16 0.00071 0.042 14.0 0.7 1 23 798 821 798 821 0.97

13 16 1.5e-05 0.00086 19.3 0.5 1 23 840 863 840 863 0.97

14 16 0.034 2 8.7 0.2 1 23 873 895 873 895 0.94

15 16 2.2e-05 0.0013 18.7 3.3 1 23 901 923 901 923 0.99

16 16 4.7e-05 0.0028 17.7 0.9 1 23 929 951 929 951 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	6e-05	0.0036	17.4	5.9	1	23	171	194	171	194	0.97
2	16	6.4e-05	0.0038	17.3	1.7	1	23	243	266	243	266	0.98
3	16	0.00076	0.045	13.9	2.8	1	23	332	355	332	355	0.94
4	16	0.0076	0.45	10.7	0.4	2	23	407	428	406	428	0.96
5	16	9.3	5.5e+02	1.0	1.3	1	20	541	560	541	562	0.82
6	16	0.018	1.1	9.6	0.6	1	23	571	593	571	593	0.94
7	16	0.00026	0.015	15.4	2.1	1	23	600	622	600	623	0.95
8	16	0.00041	0.024	14.7	1.4	2	23	631	652	630	652	0.96
9	16	0.011	0.66	10.2	0.1	3	22	680	699	678	702	0.88
10	16	0.011	0.67	10.2	1.1	1	23	738	761	738	761	0.96
11	16	0.016	0.92	9.8	0.7	1	22	768	789	768	789	0.97
12	16	0.00071	0.042	14.0	0.7	1	23	798	821	798	821	0.97
13	16	1.5e-05	0.00086	19.3	0.5	1	23	840	863	840	863	0.97
14	16	0.034	2	8.7	0.2	1	23	873	895	873	895	0.94
15	16	2.2e-05	0.0013	18.7	3.3	1	23	901	923	901	923	0.99
16	16	4.7e-05	0.0028	17.7	0.9	1	23	929	951	929	951	0.98

Sequence Information

Coding Sequence: ATGACAAGATTGTGCAGAATCTGCGGAAACGGAGATGGGCGCTATTGGATTGAGACGCCATTGATTAAATACGCAGATAAAACATACAATCAACTGCTGCTGGAGCTAACTAAACTTGAGGTCGCATTGGATCAAGCTGACAAGCTGCCGCCCTGGATTTGTCGCAACTGTACTCACAGTTTGGAGAATGCGTACGACTTTGTGCTGCAAGCGCGTAAAACTCATGAGCTTTGGCTTCAGAAGATGTCAAGAGAATCTCCTTTGAATGTTACCGAAATAGCCACTTTGGAGTGTCTGCAAGAGACACCTATACATTTGCTGGATATAGAGGGCGTTACAATTAAAATGGAAGAGCCCTCAGAGCCTGTCACGACGTCAGCAGACCCAACCAACCTTATTGATCCATTGATTAAGAAAACAATTGTGGATGATGATACCGAAGATgaagatgatgacgatgatgtgcCACTCAAGCAACGCCGgacagcacacacaaaattgCCAATGCTGCACAAGTGCAATAAGTGCGACAAGTCCTTTAAATATGTCACAAACCTCTTCAGACACAAGCAGAGGGATCATAGTCCAAATCGCTGCCGACCCAAAGCACGGGAAGCAGACGAAAAGACTCACAACTCAGAACCATTTCTACACAACCTGATAAAGAGCTCCATGACAGAACGCAGCAGCGCGGAAGActTGGAAAATGAAACAGTCGATAGCTATTACAAGTGTGATCAATGCGACAAATCCTACAAGTACATTATGCTGCTCATTAAGCACAAGCGCAAGGCACACGTTTCCAGCCAGCTGCCAGCGAAGCCTAAGCCAATTGGATGTAGCAATTCAGGTACAGAAGAAACGCTTCAGACGAGAGGATCACAGCGACAGCACTCGAAGCCCTCTAGCACAGATTCTCTTGTGCATAGCATCATTAAAGAGATCAACATACCCGATGAAGATGATACCGACAACTCCAGTGCAGACAATTACTACAAATGCGATCAATGCGACAAGTCTTATAAATACATTGTAAGTCTCATCAAGCACAAGCACAACGAGCACAAGACGTACCAGGCTTCCGATGAAGACGAAGAGGAAGCGACTTCTTCCAGATATACAGCAGACACACCTGCCATTTTGAAGCCCTCCCGCATCGATCGACGCGTGAAAGGCTTTGATTTGCATCGCTGCAAGCCGAACGGCTCAAAGGAGATTCAATGCATGATCTGTCTGCGCAGATTTATCAAACTTCGTGAGCTGCGCGATCATTTAAAGGCGCACCCCGAAGACTTTACATTCGAAGCTCACGGTGAGCCCATTGAGCGCATAGCCGAGGGCTTCTACAAAACGGCCGTAGAATCCACAGTTGCTGGCCTAAAGCAGCGCATTTTCAATGATTTGAAGGTGGGAGTGTACGGACGCTACTACTCCATAACGAATGAGGCTCGCTACGAGATGAATCTGGATAGCTCGGACACAGATAGCGATGGAGAGGCGGATGTTGTCGAGCGACACAGTTATGCTTGTGAGCTGTGTAAATCGCCCGCCGCTGTGTGGCCACGCAAATATCAATTGCACGAGCATCATAGACAAGAGCACACGTGGCTGGAGGCGCCGCATGTTTGCCAGCGTTGTGATTCACGTTTCCTGAGCGCCAAGCTTCTAGATCACCATACGCTCAAACTTTGTCAAAATACGCTAAAGCGCTTCATGTGCGATAAGTGTCCACAGCGCTTCTTCTGGCGGCGCAATTTACGCGCGCATCTTGTGGAGCACAAAAACAAGCAAGACACATATCCCTGTGATCAATGCTCGCGCAGCTTTCAGGATAAGAGCGCTGTGACCAAGCACAAACTAATGCATCATGATGTCAGCAACGAGCTTTTACCCTGCCGCTGGTGCACACGCACCTTCTATCGCCCTGCGCTGTTGCACAAGCATGTGCAGCGTCACGGCTTTAGCGGCGAGGATCTGCCCTTGGCAGAGACTCTTCTGGCAGATGCTGCCAAGACATCCGGACCCAAGACCATCATTTGTAAACTATGCGACATGCAGTTTGTTAGCATTGCTGATCTGCGACGGCACTTCTCAATGCAGGCGCACAGTGAACAGGCCTCAAACTATATGATAAGCACCGAAGAAGGCTTTGAGTTGCTGCTAGATGAAACGGATGAAAGCGACGATGATTCCGCGGGCTCTGGTAAATCATATAAATGTGCTCTATGCGATATGAATTTTCAACGACGGCGCGACATGAGCGAGCATCAGTATTCCCTACATACCTTCGACAAGCTGCCATATTCCTGTGAGCATTGTATTTACAAGACCGTTGACAAGTCCATGCTGGAGCAGCATTTGCGTACGCAGTGCCTCAACCAGGAAAAGAAATTCAAGTGCTCACGCTGCGGGTACAAATTTATGTGGCCTGAAAATCTGGAACAGCACATGTCCAGTCAACATCCCAAATCATCCAATCAGGCGCCCGTTACGATTAAGCGAAGTAGGCGTTTCAGATATCAATGTCCACACTGCTGGCGCTCCTTTGTAGTGCAGCCAAGCCTGGATAAGCACATACGCGACATGCATGTCGCTAAAAAGAATCCAGGCAAGAAGTATCTCTGCTCACTATGCGGCCTGGAATCTCTGACGCCCAACAAGCTGAACATACACATGCGTCGTCATAACGGCGAGAAGCCATTCAAATGCGATCTCTGTGACATGTCCTTTACAGTGCATTACGAACTAAAGGTGCATCGCCGCAAGCATACGGGTGAGCGGCCCTATCAGTGTACGTTCTGTGCCAAGGACTTTGCCCGACCGGATAAGCTTAGGCGACATGTTTACATGCATAGCGTTAAGcgctaa
Protein Sequence: MTRLCRICGNGDGRYWIETPLIKYADKTYNQLLLELTKLEVALDQADKLPPWICRNCTHSLENAYDFVLQARKTHELWLQKMSRESPLNVTEIATLECLQETPIHLLDIEGVTIKMEEPSEPVTTSADPTNLIDPLIKKTIVDDDTEDEDDDDDVPLKQRRTAHTKLPMLHKCNKCDKSFKYVTNLFRHKQRDHSPNRCRPKAREADEKTHNSEPFLHNLIKSSMTERSSAEDLENETVDSYYKCDQCDKSYKYIMLLIKHKRKAHVSSQLPAKPKPIGCSNSGTEETLQTRGSQRQHSKPSSTDSLVHSIIKEINIPDEDDTDNSSADNYYKCDQCDKSYKYIVSLIKHKHNEHKTYQASDEDEEEATSSRYTADTPAILKPSRIDRRVKGFDLHRCKPNGSKEIQCMICLRRFIKLRELRDHLKAHPEDFTFEAHGEPIERIAEGFYKTAVESTVAGLKQRIFNDLKVGVYGRYYSITNEARYEMNLDSSDTDSDGEADVVERHSYACELCKSPAAVWPRKYQLHEHHRQEHTWLEAPHVCQRCDSRFLSAKLLDHHTLKLCQNTLKRFMCDKCPQRFFWRRNLRAHLVEHKNKQDTYPCDQCSRSFQDKSAVTKHKLMHHDVSNELLPCRWCTRTFYRPALLHKHVQRHGFSGEDLPLAETLLADAAKTSGPKTIICKLCDMQFVSIADLRRHFSMQAHSEQASNYMISTEEGFELLLDETDESDDDSAGSGKSYKCALCDMNFQRRRDMSEHQYSLHTFDKLPYSCEHCIYKTVDKSMLEQHLRTQCLNQEKKFKCSRCGYKFMWPENLEQHMSSQHPKSSNQAPVTIKRSRRFRYQCPHCWRSFVVQPSLDKHIRDMHVAKKNPGKKYLCSLCGLESLTPNKLNIHMRRHNGEKPFKCDLCDMSFTVHYELKVHRRKHTGERPYQCTFCAKDFARPDKLRRHVYMHSVKR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00567692;
90% Identity: iTF_00551028;
80% Identity: -