Basic Information

Insect: Drosophila differens
Gene Symbol: -
Assembly: GCA_037043665.1
Location: JBAMAZ010000299.1:1430332-1433880[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 8.9e-05 0.0058 17.0 5.0 1 23 175 198 175 198 0.97

2 16 0.0019 0.12 12.8 3.9 1 23 247 270 247 270 0.96

3 16 0.00087 0.056 13.9 2.8 1 23 336 359 336 359 0.94

4 16 0.0087 0.56 10.7 0.4 2 23 411 432 410 432 0.96

5 16 1 65 4.2 1.8 1 21 545 565 545 566 0.88

6 16 0.021 1.3 9.6 0.6 1 23 575 597 575 597 0.94

7 16 0.00029 0.019 15.4 2.1 1 23 604 626 604 627 0.95

8 16 0.00047 0.03 14.7 1.4 2 23 635 656 634 656 0.96

9 16 0.014 0.93 10.0 0.1 2 21 683 702 682 706 0.88

10 16 0.53 34 5.1 0.6 1 23 744 767 744 767 0.91

11 16 3.7 2.4e+02 2.5 1.9 1 22 774 795 774 795 0.93

12 16 0.0028 0.18 12.3 2.5 1 23 804 827 804 827 0.98

13 16 1.7e-05 0.0011 19.3 0.5 1 23 848 871 848 871 0.97

14 16 0.1 6.5 7.4 0.2 1 23 881 903 881 903 0.94

15 16 2.5e-05 0.0017 18.7 3.3 1 23 909 931 909 931 0.99

16 16 5.4e-05 0.0035 17.7 0.9 1 23 937 959 937 959 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	8.9e-05	0.0058	17.0	5.0	1	23	175	198	175	198	0.97
2	16	0.0019	0.12	12.8	3.9	1	23	247	270	247	270	0.96
3	16	0.00087	0.056	13.9	2.8	1	23	336	359	336	359	0.94
4	16	0.0087	0.56	10.7	0.4	2	23	411	432	410	432	0.96
5	16	1	65	4.2	1.8	1	21	545	565	545	566	0.88
6	16	0.021	1.3	9.6	0.6	1	23	575	597	575	597	0.94
7	16	0.00029	0.019	15.4	2.1	1	23	604	626	604	627	0.95
8	16	0.00047	0.03	14.7	1.4	2	23	635	656	634	656	0.96
9	16	0.014	0.93	10.0	0.1	2	21	683	702	682	706	0.88
10	16	0.53	34	5.1	0.6	1	23	744	767	744	767	0.91
11	16	3.7	2.4e+02	2.5	1.9	1	22	774	795	774	795	0.93
12	16	0.0028	0.18	12.3	2.5	1	23	804	827	804	827	0.98
13	16	1.7e-05	0.0011	19.3	0.5	1	23	848	871	848	871	0.97
14	16	0.1	6.5	7.4	0.2	1	23	881	903	881	903	0.94
15	16	2.5e-05	0.0017	18.7	3.3	1	23	909	931	909	931	0.99
16	16	5.4e-05	0.0035	17.7	0.9	1	23	937	959	937	959	0.98

Sequence Information

Coding Sequence: ATGACAAGAACGTGTAGAATCTGTGGTGGCGCAGATGGACGCTTCTGGATCGAGACGCCAATTGATAAATACGCGGAGAAAACCTTCAATCACCTGCTGCTAGATCTAACAAAACTCGAGGTCAATGTGGATCAAGCTGATAAGCTGCCGCCATGGATCTGCCGCAACTGTGCGCACAGATTAGAAAATGCCTACGACTTTGTGCTGCAGGCGAGGGAAACTCACGAACTTTGGCTGCACAAGATGACAACAGAATCTCTTTCGGAGGACACCGAAACTGGGACGTTGGAGTGCCTGCGAGAGACACCCATTCAATTGCTGGAGATTGAGGGCGTCACAATTAAAATGGAGGAGGCAACCGAACCAGCCGTGCCACAAACAGATTCAGTCGGCTCGATTGATCCGCTAATTAAAAAGAGTCGAGAGGATGATGCCAGCAATAATGATGATAacgctgatgatgacgatgatgatatTCCGCTCAAGCAGCGCCGGATTGCACGCACAAAACTGCCGACGATGCACAAGTGCAATAAGTGCGACAAGGCCTTCAAATATGTAACGAATCTCTTCAGGCACAAACAACGAGATCACACTCCAGAGCACAACCAAACCAAAGAACAGGCAGCAGTGGAAAGTGAAAAGGCTGATCGCTTGAAACCCTTCTTAAACGATGTAATCAAGAGATCCATTGCAGCAACACACAGCAGCGAGGCAGACGAATTGGCGGATAATTACTACAAGTGCGATCAATGCGACAAATCCTACAAGTACATAATGCTGCTGATCAGACACAAGCACAAGACGCACGCTTCCAACCAGTGTCCAGCAGAGCCCAGACCAATTAGAAGAAGCGGTTCGAGTGCAGAGCAAACTAATACTAAACAACGATCACCTCCTCAGCGCTCGAAACCGACCAGTACAGATTCGCTTGTGCACAGCATCATCAAAGAGATCAACTTACCCGATGAGGACGATGCAGACAGTTCCAGTGCCGACAATTACTACAAGTGCGACCAGTGCGACAAGTCGTACAAATACATTGTGAGTCTCatcaagcacaagcacaacgAGCACAAGGAATACAGGGATTCCGAGGAGGACGAAGATGGGGCAACGTCCTCCAGATATGCAGCAGATGCCACTGCTATGTCGAAGCCGTCGCGCATTGATCGTCGCGTCAAGGGCTTCGATTTGAATCGCTGCCGGCCAAACGGTTCCAAAGAGATTCAGTGCATGATCTGTCTGCGCAGATTCATCAAGTTGCGCGAGCTGCGTGATCACCTGAAAGCCCATCCTAAAGACTTTACATTTGATGCTCATGGCGAGCCGATTGAGCGCATTGCCGAGGGGTTCTATAAGACAGCCGTGGAATCCACAGTTGCGGGCCTGAAGCGACGCATCTTCAATGATCTCAAGGTTGGCATGCTCGGACGCTACTATTCCATAACAAATGAGGCACGGTACGAGATGAATCTGGACAGCTCGGACACAGACAGCGACGGCGAAGCGGATGTTGTGCAGCGGCATTCGTATGCCTGCGAACTGTGCGACTCCGCCGATGCCGTCTGGCCACGCAAATATCAATTGCACGAGCATCATCGGCAGCAGCACACCTGGCTGGAGGCGCCGCACGTCTGCCAGCGCTGTGACTTCCGCTTCCTGAGCGCGCAGCTGCTCGAGCATCATACGCAAAAGTTGTGCCAGAACACCCTGAAGCGCTTCATGTGCGACAAATGTCCACAGCGCTTTTTTTGGCGACGCAATCTACGTGCGCATCTTGTCGAGCATAAAAACAAGCAGGATACGTATCCGTGTGATCAGTGTTCGCGCAGCTTTCAGGACAAGAGCGCCGTAACGAAGCACAAGCTGATGCACCACGATGTCCACAACGAGCTGTTGCCCTGTCGCTGGTGCACGCGCACCTTCTACCGGCCGGCGCTGTTGCACAAGCATGTGCAGCGTCACGGCTTTAGTGGGGAGGATCTGCCGCTGGCAGAGACACTGCTGGCGGATGCCGCCAAGCCATCCGGTACGAAGACGATTGTCTGCAAACTTTGCGATATGCAGTTCATTAGCATTGGCGACCTGCGGCGACACAACTCGATGCAGGCGCACAGTGAGCAGGTGTCCAACTATATGATAAGCACCGAGGAGGGATTCGAGCTGCAGCTGGATGAAACGGACGAGAGTGATGAGGAGCCCACGAGTACTGCTGCCAGCCGATCTTATCGATGCGATCTGTGCGAGATGAGCTTCCTGCGAATGCGTGACATGAGCGAACATCAGTATTCACTGCACACCTTCGACAAGCTGCCACATTCCTGTGCGCATTGCATTTATAAGACAGTCGATAAGACCATGCTAGAGCACCATCTGAGCACACAGTGTCTTAACGAGGAGAAGAAATTCAAGTGCTCTCGTTGCGGCTACAAATTCATGTGGCACGAAAATCTGGAACAGCACATGAGCACTCTGCATCCCAAGTCATCATCTAGTCAGACGCCCGTTGCGGCGACAAAGCGGAGTAGACGTTTCCGATACCAGTGTCCACACTGCTGGCGCTCGTTTGTGGTACAGCCCAGCCTGGACAAGCACATTCGGGATATGCATGTGGCGAAAAAGAATCCCGGCAAGAAGTATCTATGCTCGCTGTGCGGCTTGGAGTCGCTGACGCCAAATAAGCTCAGCATACACATGCGGCGTCACAACGGCGAGAAGCCATTCAAATGTGATCTCTGCGACATGTCCTTCACCGTGCACTACGAGCTGAAGGTTCATCGCCGCAAGCATACCGGCGAGCGACCCTATCAGTGCACTTTCTGTGCCAAGGATTTCGCCCGGCCGGATAAGCTAAGACGGCATGTTTACATGCATAGCGTTAAGCGTTAA
Protein Sequence: MTRTCRICGGADGRFWIETPIDKYAEKTFNHLLLDLTKLEVNVDQADKLPPWICRNCAHRLENAYDFVLQARETHELWLHKMTTESLSEDTETGTLECLRETPIQLLEIEGVTIKMEEATEPAVPQTDSVGSIDPLIKKSREDDASNNDDNADDDDDDIPLKQRRIARTKLPTMHKCNKCDKAFKYVTNLFRHKQRDHTPEHNQTKEQAAVESEKADRLKPFLNDVIKRSIAATHSSEADELADNYYKCDQCDKSYKYIMLLIRHKHKTHASNQCPAEPRPIRRSGSSAEQTNTKQRSPPQRSKPTSTDSLVHSIIKEINLPDEDDADSSSADNYYKCDQCDKSYKYIVSLIKHKHNEHKEYRDSEEDEDGATSSRYAADATAMSKPSRIDRRVKGFDLNRCRPNGSKEIQCMICLRRFIKLRELRDHLKAHPKDFTFDAHGEPIERIAEGFYKTAVESTVAGLKRRIFNDLKVGMLGRYYSITNEARYEMNLDSSDTDSDGEADVVQRHSYACELCDSADAVWPRKYQLHEHHRQQHTWLEAPHVCQRCDFRFLSAQLLEHHTQKLCQNTLKRFMCDKCPQRFFWRRNLRAHLVEHKNKQDTYPCDQCSRSFQDKSAVTKHKLMHHDVHNELLPCRWCTRTFYRPALLHKHVQRHGFSGEDLPLAETLLADAAKPSGTKTIVCKLCDMQFISIGDLRRHNSMQAHSEQVSNYMISTEEGFELQLDETDESDEEPTSTAASRSYRCDLCEMSFLRMRDMSEHQYSLHTFDKLPHSCAHCIYKTVDKTMLEHHLSTQCLNEEKKFKCSRCGYKFMWHENLEQHMSTLHPKSSSSQTPVAATKRSRRFRYQCPHCWRSFVVQPSLDKHIRDMHVAKKNPGKKYLCSLCGLESLTPNKLSIHMRRHNGEKPFKCDLCDMSFTVHYELKVHRRKHTGERPYQCTFCAKDFARPDKLRRHVYMHSVKR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00567692;
90% Identity: iTF_00570569;
80% Identity: -