Dmac006599.1
Basic Information
- Insect
- Drosophila maculinotata
- Gene Symbol
- -
- Assembly
- GCA_035045305.1
- Location
- JAWNPD010000335.1:22790861-22794544[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 16 8.7e-05 0.0059 17.1 6.1 1 23 169 192 169 192 0.97 2 16 0.0014 0.093 13.3 3.1 1 23 244 267 244 267 0.96 3 16 0.00089 0.06 13.9 2.8 1 23 333 356 333 356 0.94 4 16 0.0089 0.6 10.7 0.4 2 23 408 429 407 429 0.96 5 16 9.8 6.7e+02 1.2 2.5 1 20 542 561 542 563 0.85 6 16 0.021 1.4 9.6 0.6 1 23 572 594 572 594 0.94 7 16 0.0003 0.02 15.4 2.1 1 23 601 623 601 624 0.95 8 16 0.00044 0.03 14.8 1.1 2 23 632 653 631 653 0.96 9 16 0.0016 0.11 13.1 0.1 2 22 680 700 679 703 0.89 10 16 0.0018 0.13 12.9 0.8 1 23 740 763 740 763 0.96 11 16 0.098 6.7 7.5 1.6 1 22 770 791 770 791 0.97 12 16 0.0015 0.1 13.1 1.4 1 23 800 823 800 823 0.97 13 16 1.7e-05 0.0012 19.3 0.5 1 23 842 865 842 865 0.97 14 16 0.1 7 7.4 0.2 1 23 875 897 875 897 0.94 15 16 2.6e-05 0.0018 18.7 3.3 1 23 903 925 903 925 0.99 16 16 5.5e-05 0.0037 17.7 0.9 1 23 931 953 931 953 0.98
Sequence Information
- Coding Sequence
- atgacaAGAACTTGCAGAATATGCGGTGGCGCGGATGGACGCTTTTGGATCGAGACGCCAGTCGATAAATATGCGGAGAAGACCTTCAATCAACTGCTGCTGGAACTAACAAAAATCGAGGTTGCATTGGATCAGGCTGAGAAGCTGCCTCAATGGATTTGTCGCAGCTGTGCCCAGAGATTAGAGAATGCCTACGATTTTGTGCTGCAGGCGCGGGAAACCCACAAATTGTGGCTACAAAAAAGGAGAATCGACCCCTTAACGGAGGACACCGAAAGGGACATCTTGGAATGCCTGCGGGAGACGCCAATCCAATTGCTGGAGATTGAGGGAGTTACCATTAAAATGGAGGAGCCGACAGAACCTGCCATGCCCCAAGCGGATCCTACCAGTCCATCGATTGATCCTCTCTTTAAGAAGAGCCGTGTGGATGATTCTAatactgatgatgatgatgtgccGCTCAGGCAACGGCGGGCAGTCCACACAAAATTACCAACGATGCACAAGTGCAACAAGTGTGATAAAACCTTCAAATATGTTACAAATCTCTTCAGGCACAAGCAGCGGGATCACAGCCCGGAACGCAGCCAAACCAAGACGTTATCTGGGCAGGAGAATGCAAAGACTGATCGTTCAGAACCATTCCTACACAACCTCATCAAAAGCTCCATAGCAGTACATGGCAGCCGGGCAGCAGAcTTGGACAGTGAATCCGCGGATAACTACTACAAATGCGATCAATGTGACAAATCCTACAAGTACATAATGCTGCTCATCAAGCACAAGCACAAGGCTCACGTTTCGAGCTATTTGTCAGCAGAGCCAAGACCAATTAGAGGATGTGGGTCGAGCGCAGAGCAAACAGATACAAGAATAGCCGCTCAGCGTCAGTGGTCGAAGCCGCCCAGCACAGATTCTCTAGTGCATAGCATCATAAAGGAGATCAGCTTGCCCGATGAGGACGAAGCAGATAGTTCCAGTACCGATAACTACTACAAGTGCGATCAATGCGATAAGTCCTACAAATATATTGTGAGTCTTATCAAGCACAAGCACAACGAGCACAAAGAGTACAAGGATTCCGATGAGGATGAAGATGAAGCCACCTCCTCCAGATATGCAGCGGATACAACTTCCATATCGAAGCCCTCGCGCATTGATCGTCGCGTCAAGGGTTTCGATTTGCATCGCTGCAAGCCGAACGGTTCCAAGGAGATTCAATGCATGATTTGCCTGCGCAGATTCATCAAATTGCGAGAACTACGCGATCATTTGAAAGCGCATCCCAAAGACTTTACATTCGATGGTCATGGCGAGCCCATTGAGCGAATTGCCGAGGGCTTCTACAAGACTGCCGTGGAGTCCACAGTTGCGGGCTTGAAGCGACGCATCTTCAACGATCTCAAGGTGGGCATGCTAGGACGCTACTATTCCATAACCAATGAGGCCCGCTACGAAATGAATCTCGACAGCTCGGACACCGACAGCGATGGCGAAGCGGATGTTGTGGAGCGGCATTCCTACACCTGTGAGTTGTGCGACTCACCTACCGCCGTGTGGCCACGCAAATATCAATTGCACGAGCATCATCGACAACATCACACCTGGCTAGAGGCGCCGCACGTCTGCCAGCGCTGTGACTCGCGTTTCCTCAGCGCCCAACTGCTCGAACATCATACGCATAAATTGTGTCAGAATACCCTAAAGCGCTTCATGTGTGACAAGTGCCCGCAGCGCTTCTTCTGGCGACGCAATCTACGCGCCCATCTGGTCGAGCACAAAAATAAGCAAGAGACGTATCCGTGTGATCAGTGCTCGCGCAGTTTTCAGGATAAGAGCGCAGTGACAAAGCACAAGTTAATGCATCACGATGTCAGCAATGAGCTCATACCATGTCGCTGGTGCACACGTACCTTTTATCGTCCGGCGCTGCTGCACAAGCATGTGCAGCGTCATGGCTTCAATGGCGAGGATCTGCCCCTGGCGGAGACACTGCTCGCAGATGCCGCCAAGCCATCCGGGACGAAGACAATTGTTTGCAAGCTATGCGACATGCAATTTGTGAGCATTGCCGATCTGCGACGACACATCTCGATGCAGGCGCATAGTGAACAGTCCTCAAATTATATGATTAGCACCGAGGAGGGCTTCGAGCTGCAACTGGACGAAACGGATGAAAGCGATGAGGAGCCCACAAGTACGGCCAGCAGATCCTACAAATGCGATCTGTGCGAGTTGAGCTTCATTCGCAGGAGGGATATGAGCGAACATCAATATTCGCTGCACACCTTCGATAAGCTTCCATATTCCTGTGAGCATTGCATTTACAAGACTGTCGATAAGACCATGCTGGAGCATCATCTGCGCACGCAGTGCCTCAACCAGGAGAAGAAATTCAAATGCTCGCGATGTGGCTACAAGTTCATGTGGCGCGAAAATCTGGAACAGCACATGAGCAGCCAGCATCCGAAGTCATCTAATCAGACGCCCGTTGCAGCGAAGCGCAGCAGACGTTTCAGATACCAATGTCCACACTGCTGGCGCTCATTCGTGGTGCAGCCCAGCTTGGACAAGCATATACGCGACATGCATGTGGCGAAAAAGAATCCCGGCAAGAAATATCTGTGCTCACTGTGCGGCCTGGAGTCACTGACGCCTAACAAGCTCAGCATACACATGCGTCGTCACAACGGCGAGAAGCCATTCAAATGTGATCTCTGCGACATGTCCTTTACCGTACACTACGAGCTGAAGGTGCATCGCCGCAAACACACCGGCGAGCGACCCTATCAGTGCACGTTCTGTGCCAAGGATTTCGCCAGGCCGGATAAACTTAGGCGGCATGTTTATATGCACAGCGTAAAGCGTTAA
- Protein Sequence
- MTRTCRICGGADGRFWIETPVDKYAEKTFNQLLLELTKIEVALDQAEKLPQWICRSCAQRLENAYDFVLQARETHKLWLQKRRIDPLTEDTERDILECLRETPIQLLEIEGVTIKMEEPTEPAMPQADPTSPSIDPLFKKSRVDDSNTDDDDVPLRQRRAVHTKLPTMHKCNKCDKTFKYVTNLFRHKQRDHSPERSQTKTLSGQENAKTDRSEPFLHNLIKSSIAVHGSRAADLDSESADNYYKCDQCDKSYKYIMLLIKHKHKAHVSSYLSAEPRPIRGCGSSAEQTDTRIAAQRQWSKPPSTDSLVHSIIKEISLPDEDEADSSSTDNYYKCDQCDKSYKYIVSLIKHKHNEHKEYKDSDEDEDEATSSRYAADTTSISKPSRIDRRVKGFDLHRCKPNGSKEIQCMICLRRFIKLRELRDHLKAHPKDFTFDGHGEPIERIAEGFYKTAVESTVAGLKRRIFNDLKVGMLGRYYSITNEARYEMNLDSSDTDSDGEADVVERHSYTCELCDSPTAVWPRKYQLHEHHRQHHTWLEAPHVCQRCDSRFLSAQLLEHHTHKLCQNTLKRFMCDKCPQRFFWRRNLRAHLVEHKNKQETYPCDQCSRSFQDKSAVTKHKLMHHDVSNELIPCRWCTRTFYRPALLHKHVQRHGFNGEDLPLAETLLADAAKPSGTKTIVCKLCDMQFVSIADLRRHISMQAHSEQSSNYMISTEEGFELQLDETDESDEEPTSTASRSYKCDLCELSFIRRRDMSEHQYSLHTFDKLPYSCEHCIYKTVDKTMLEHHLRTQCLNQEKKFKCSRCGYKFMWRENLEQHMSSQHPKSSNQTPVAAKRSRRFRYQCPHCWRSFVVQPSLDKHIRDMHVAKKNPGKKYLCSLCGLESLTPNKLSIHMRRHNGEKPFKCDLCDMSFTVHYELKVHRRKHTGERPYQCTFCAKDFARPDKLRRHVYMHSVKR
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00567692;
- 90% Identity
- -
- 80% Identity
- -