Dspr011216.1
Basic Information
- Insect
- Drosophila sproati
- Gene Symbol
- -
- Assembly
- GCA_018904355.1
- Location
- JAEIFY010000003.1:1080509-1084052[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 16 2.9e-05 0.0019 18.3 5.3 1 23 141 164 141 164 0.97 2 16 0.0015 0.1 12.9 3.9 1 23 216 239 216 239 0.96 3 16 0.0007 0.047 13.9 2.8 1 23 305 328 305 328 0.94 4 16 0.007 0.47 10.8 0.4 2 23 380 401 379 401 0.96 5 16 2.9 2e+02 2.5 3.0 1 20 514 533 514 535 0.85 6 16 0.017 1.1 9.6 0.6 1 23 544 566 544 566 0.94 7 16 0.00024 0.016 15.4 2.1 1 23 573 595 573 596 0.95 8 16 0.00038 0.025 14.8 1.4 2 23 604 625 603 625 0.96 9 16 0.012 0.78 10.1 0.1 2 21 652 671 651 675 0.88 10 16 0.096 6.5 7.2 0.9 1 23 713 736 713 736 0.95 11 16 1.2 82 3.7 2.2 1 22 743 764 743 764 0.93 12 16 0.00047 0.032 14.5 1.2 1 23 773 796 773 796 0.98 13 16 1.3e-05 0.0009 19.3 0.5 1 23 817 840 817 840 0.97 14 16 0.081 5.5 7.4 0.2 1 23 850 872 850 872 0.94 15 16 2.1e-05 0.0014 18.8 3.3 1 23 878 900 878 900 0.99 16 16 4.3e-05 0.0029 17.7 0.9 1 23 906 928 906 928 0.98
Sequence Information
- Coding Sequence
- ATGACAAGAACGTGTAGAATCTGCGGTGGCGCAGATGGACGCTTCTGGATCGAGACGCCAATTGATAAATACGCGGAGAAAACATTCAATCACCTGCTGCTGGAGCTAACAAAACTCGAGGTCACTGTGGATCAAGCTGATAAGCTACCGCCATGGATCTGCCGCAACTGTGCGCACAAATTAGAAAATGCCTACGACTTTGTGCTGCAGGCGAGGGAAACTCACGAGCTTTGGCTGAACAAGATCACAACAGAATCTCTATCGGAGGACACCGAAACTGGGACGTTGGAGTGCCTGCGAGAGACACCCATTCAATTGCTGGAGATTGAGGGCGTCACAATTAAAATGGAAGAGGCAACTGAACCAGCCGTGCCACAAACAGATTCACGCCGGATTGCAAGCACAAAACTGCCAACGATGCACAAGTGCAATAAGTGCGACAAGGCCTTCAAATATGTAACGAATCTCTTCAGGCACAAGCGACGAGATCACTCTCCAGAGAACAGCCATACCAAAGAACAGGCAGCAGTGGAAAGTGAAAAGACTGATGGCATGAAACCGCTCTTAAACGATGTAATCAAGAGCTCTATTGCAACAACACACAGCAGCGAGGCAGACTTGGAAAGCGAATTGGCGGATAGTTACTACAAGTGCGATCAATGCGACAAATCCTACAAGTACATAATGCTGCTGATCAGACACAAGCACAAGACGCACGCTTCCAGCCAGTGTCTAGCACAGCCCAGACCAATTAGAAGAAGCGGTTCGAGTGCAGAGCAAACTAATACTAAACAGGGTTCACCGCCTCAGCGCTCGAAACCGACCAACACAGATTCGCTTGTGCACAGCATCATCAAAGAGATCAACTTACCCGATGAAGACGATGCAGACAGTTCCAGTGCCGACAATTACTACAAGTGCGACCAGTGTGACAAGTCGTACAAATACATTGTGAGTCTCATCAAGCACAAACACAACGAGCACAAGGAATATAGGGATTCCGATGAGGATGAAGATGGGGCAACGTCTTCCAGATATGCAGCAGATGTCACTGCTATGTCGAAGCCGTCGCGCATTGATCGTCGCGTCAAAGGCTTCGATTTGAATCGCTGCCGCCCAAACGGTTCCAAAGAGATTCAGTGCATGATCTGTCTGCGCAGATTCATCAAGTTGCGCGAGCTGCGTGATCACCTGAAAGCCCATCCTAAAGATTTCACATTCGATGCTCATGGCGAGCCGATTGAGCGCATTGCCGAGGGGTTCTATAAGACAGCCGTGGAATCCACAGTTGCGGGCCTCAAGCGACGGATCTTCCACGATCTCAAGGTGGGCATGCTCGGACGCTACTATTCCATAACAAATGAGGCACGGTACGAGATGAATCTGGACAGCTCGGACACGGACAGCGACGGCGAAGCGGATGTTGTGCAGCGGCATTCGTATGCCTGCGAATTGTGCGACTCCGCCGATGCCGTCTGGCCACGCAAATATCAATTGCACGAGCATCATCGGCAGCAGCACACCTGGCTGGAAGCGCCGCACGTCTGCCAGCGCTGTGACTTCCGCTTCCTGAGCGCGCAGCTGCTCGAGCATCATACGCACAAGTTGTGCCAGAACACCCTGAAGCGCTTCATGTGCGACAAGTGTCCACAGCGCTTCTTTTGGCGACGCAATCTACGTGCGCATCTTGTCGAGCACAAAAACAAGCAGGAGACGTATCCGTGTGATCAGTGCTCGCGCAGCTTTCAGGACAAGAGCGCCGTGACGAAGCACAAGCTGATGCACCACGATGTACACAACGAGCTGTTGCCCTGTCGCTGGTGCACGCGCACCTTCTACCGGCCGGCGCTGTTGCACAAGCATGTACAGCGTCACGGCTTTAGTGGAGAGGATCTGCCGCTGGCAGAGACACTGCTGGCGGATGCCGCCAAGCCATCTGGTACGAAGACGATTGTCTGCAAACTTTGCGATATGCAGTTCATTAGCATTGGCGACCTGCGGCGACACAACTCGATGCAGGCGCACAGTGAGCAGGTGTCCAACTATATGATAAGCACCGAGGAGGGATTCGAGCTGCAGCTGGATGAAACGGACGAGAGTGATGAGGAGCCCACAAGTACTGCTGCCAGCCGATCTTATCGATGCGATCTGTGCGAGATGAGTTTCCTGCGAAGGCGCGACATGAGCGAACATCAATATTCGCTGCACACCTTCGACAAGCTGCCACATTCTTGTGAGCATTGCATTTACAAGACAGTCGATAAGACCATGCTAGAGCACCATCTGAGCACACAGTGTCTTAACGAGGAGAAGAAATTCAAGTGCTCTCGTTGCGGCTACAAATTCATGTGGCGCGAAAATCTGGAGCAGCACATGAGCACTCTGCATCCAAAGTCATCATCTAGTCAGACGCCCGTTGCGGCGACAAAGCGGAGTAGACGTTTCCGATACCAGTGTCCACACTGCTGGCGCTCGTTTGTGGTGCAGCCCAGCCTGGACAAGCACATTCGGGACATGCATGTGGCGAAAAAGAATCCCGGCAAGAAGTATCTATGCTCGTTGTGCGGCCTGGAGTCGCTGACCCCAAATAAGCTCAGCATACACATGCGGCGTCACAACGGCGAGAAGCCATTCAAATGTGATCTCTGCGACATGTCCTTCACCGTGCACTACGAGCTGAAGGTTCATCGCCGTAAGCATACCGGCGAGCGACCCTATCAGTGCACATTCTGTGCCAAGGATTTTGCCCGGCCGGATAAGCTAAGACGGCATGTTTACATGCATAGCGTTAAGCGTTAA
- Protein Sequence
- MTRTCRICGGADGRFWIETPIDKYAEKTFNHLLLELTKLEVTVDQADKLPPWICRNCAHKLENAYDFVLQARETHELWLNKITTESLSEDTETGTLECLRETPIQLLEIEGVTIKMEEATEPAVPQTDSRRIASTKLPTMHKCNKCDKAFKYVTNLFRHKRRDHSPENSHTKEQAAVESEKTDGMKPLLNDVIKSSIATTHSSEADLESELADSYYKCDQCDKSYKYIMLLIRHKHKTHASSQCLAQPRPIRRSGSSAEQTNTKQGSPPQRSKPTNTDSLVHSIIKEINLPDEDDADSSSADNYYKCDQCDKSYKYIVSLIKHKHNEHKEYRDSDEDEDGATSSRYAADVTAMSKPSRIDRRVKGFDLNRCRPNGSKEIQCMICLRRFIKLRELRDHLKAHPKDFTFDAHGEPIERIAEGFYKTAVESTVAGLKRRIFHDLKVGMLGRYYSITNEARYEMNLDSSDTDSDGEADVVQRHSYACELCDSADAVWPRKYQLHEHHRQQHTWLEAPHVCQRCDFRFLSAQLLEHHTHKLCQNTLKRFMCDKCPQRFFWRRNLRAHLVEHKNKQETYPCDQCSRSFQDKSAVTKHKLMHHDVHNELLPCRWCTRTFYRPALLHKHVQRHGFSGEDLPLAETLLADAAKPSGTKTIVCKLCDMQFISIGDLRRHNSMQAHSEQVSNYMISTEEGFELQLDETDESDEEPTSTAASRSYRCDLCEMSFLRRRDMSEHQYSLHTFDKLPHSCEHCIYKTVDKTMLEHHLSTQCLNEEKKFKCSRCGYKFMWRENLEQHMSTLHPKSSSSQTPVAATKRSRRFRYQCPHCWRSFVVQPSLDKHIRDMHVAKKNPGKKYLCSLCGLESLTPNKLSIHMRRHNGEKPFKCDLCDMSFTVHYELKVHRRKHTGERPYQCTFCAKDFARPDKLRRHVYMHSVKR
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00567692;
- 90% Identity
- iTF_00570569;
- 80% Identity
- -