Bcam009133.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Bombus campestris
Gene Symbol
-
Assembly
GCA_905333015.1
Location
HG995146.1:5777411-5781072[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 0.13 11 6.7 2.3 1 23 195 217 195 217 0.94
2 18 0.00032 0.025 14.9 1.4 2 23 252 273 251 273 0.98
3 18 0.0004 0.032 14.6 1.0 1 23 413 435 413 435 0.96
4 18 0.0018 0.14 12.6 0.3 2 23 439 460 438 460 0.96
5 18 0.17 14 6.3 3.2 1 23 533 556 533 556 0.94
6 18 0.00036 0.028 14.8 0.7 1 21 562 582 562 586 0.92
7 18 0.0013 0.1 13.0 2.9 2 23 665 686 664 686 0.95
8 18 2.4e-05 0.0019 18.5 4.1 1 23 743 765 743 765 0.97
9 18 0.00024 0.019 15.3 0.7 1 20 770 789 770 791 0.94
10 18 0.04 3.2 8.3 0.6 2 23 802 823 802 823 0.97
11 18 2.4e-05 0.0019 18.4 0.6 2 23 862 883 861 883 0.97
12 18 2.2e-05 0.0017 18.6 1.6 1 23 888 910 888 910 0.95
13 18 0.00012 0.0098 16.2 2.9 1 23 916 938 916 938 0.98
14 18 3.9e-06 0.00031 20.9 0.4 1 23 954 976 954 976 0.95
15 18 3.2e-07 2.5e-05 24.4 0.6 1 23 982 1004 982 1004 0.99
16 18 1.9e-05 0.0015 18.8 0.2 1 23 1010 1032 1010 1032 0.98
17 18 0.00013 0.01 16.2 4.1 1 23 1038 1060 1038 1060 0.96
18 18 0.0083 0.66 10.5 0.3 1 20 1066 1085 1066 1087 0.89

Sequence Information

Coding Sequence
ATGGAGGAGGTAATCGATCAAACTATCGCTACAGAGCAAACATCGGGAGAGTGCCTGAGTCATGAAGAAGAGGACATTAAAGTAATCATAGATGCTCCCATTAACGAAGAAATGTTAAAACACGAAAACGGGGATAACGATAgccttgaaaatatttcaacggtAGAACACGATTATATATTACAGCAAGAGTGTATATTATCTAGCACGAATGAGCAGgagcagcaacaacagcatcatcatcatcaacaACATCAACATCAACATCAACATCCCTCCGGAGAATCGTTTCAGCGGGAGGATTGCACCGAGTACGTAGATCTATTGGTAAAAGCAGCTGATGCAACGACAAAACAAGAAGATGAGgacgatgaagaagaagaaaaatcggatATTACGAACACGCCTGTTCAGCCAGATACAGATTCTCAGTGTCAAAATGAAACGAGGAGAAGCAAACGTAAATTAGTTCGGCGAAATTTTGAAACGAGACGAGATTCCGATGAAGAAaactattttgaaaatttgaatttaagctCGAGACTGAAAAAAGGTCAGTCCTCTGATCAATCggaaaaaatttttctatgttaTCTGTGCGACAAAGAGTTTTTGTCGAAAAATGTTTTGAAGGAGCATATGCATTCTCACGAAGAAGTTCGAAAGGTATTGTCTCTGAAAAAAACACCGGATACACCGCAAAAGAACGTTTATAATGTTGCAAAGTCTCCTCCATCGGGTAAGAGATCAAACAAGTGCCCGTATTGTGGCAagcaatacatatatataacctCGTTTAGTAAACATTTGAAAAAACatgaaagggagaaagaagaggGCAAAGAAGAATCAATGCCCTTAGAAATATCATTCCACGAAGACGAACATAGTCTAGATCTTGATAATTATAAAGATGCACGTCGGCATTTGGATAACGAGTATCGGAAAAAAGTCAAACAAAAAGAGGTGGGTCCAGAAGAGCGTAGacaggaagaaagagggaacGAGGCGAAAAGAGGCAATAACGATGGCggtgatggtggtggtggtggtggcggcggcggcgaaggaggaagaggaaataacaacaataacaacaatgaCGATGACAaccacgacgacgacgacgacgacgacgacgacgacgatgactaCAACGACTACAACGATAAAAGACAAGTGggtaatttgattaaaaaagagGAACAGGAGAATCGCAATGTCCGTACAGAAACGTTTGCATGCGACAAGTGCTcagagaaattttatacaaaacgtGGCTTGCAGAAACATGCGATTTCGCATGTTGTTCTCAGTTGCAGCATATGCGAAGAAGAATTCGATTCattggaaaaattaagaaaccaTCGTGCGAAGCATGTAGTTGAAGGTGTTCTAACTGAACAAGAACTTGAGATGGATACAGAATATCCAATTAATAAGGAAACGTGCGATTATGAGACAGAGGATAAAGATAGCATAGACAGAAGTCACAGGATGGAAAACAAGTCAATACCAGGATTGCTGGagacagaaaataatttatcaaagaaaaatgatagAAACATGGAGACTCATCGTCATTCGGGGATTGACTATAGTTGCAAGGTGTGTTGCCAACGATTTGCAATGAAAGAAATGTTGCAAAAACACACGGAACAGCAACATGAACGTGTAAAATCTTACAAGTGCACACAATGTAACAAAACATTTGGTAACGAACTTACTTTACGTAATCATCTTATAGCTACTAATCATAAAACTTTTCTTCATGGGCAAGAATATGACCCTAATAAACGTATTAAAAGAGTTGCTGCGAGAGCTGCACAAAagattatcgataaaattaaaaccgAGGATGGTTTGGAAGATTTCGACGAGGAAGAGGAGAATATCGATAGAATTAATCGCGCTAATGTtatagataataattatagtCGGAATAAGCGAGAAATATCTTCGCATAAGAGACATAATCATAAGAAAGAATTGGAATGTGCGAGCTGCAATAAAAGATGCAGTTCAAAGCAGTTGTTAACAAAACATATGGAGCAACATGTAAAAGACGAGCAACAACGAGTGGTCAAGTCGGAAAAGCAAAAGCAATCGGCAGATAAGAAAGATTGGCAAAGGGATTACACTAATGAGGAGATGTACCACAAGGAGAACAGAGATGACGATTATGATTCGGATTTCGAAAGCGGTTTGGATTGGCCAATGGATAATCACGAGTGTCCAAAGTGTAAAAAACGATACAGCACGAAAAAATCATTGCTCCGTCATCAATTGTTGCACGAAGAACCGAATTTCGAATGCGATATTTGCAATGTTAAGTTTTACCGCAAAGACAAACTAAAAGCTCATTATGATAAGTGTTCGGAGAAGAACCCCGATCAAGTGAGAAAGTGCAATATCTGCGGGGACACGTTTGAGAACAATGAGATTCTGCGAGAACATAGATCAAAACATGTTACCGAAGGCATTCTTACGGAAGAAGACCTGAGAGATATCGAACCGCGACCCGAGGAGAAAAAGCCAGGTGAAAAGATTGGTAGAAAGAGAAGGACTGATATCGTAGGTTTAGAGTGCACGGAATGTAACAAGCAATATACATCGAGAAAAGGGCTTTTACGACATATTCAAGTCCACGAAGGAAAAAAGTATCTGTGTGATATATGTccaaaaaaattttatagaaggGAACATTTAAAGATACACGTAGCTAAACATAACATGATTAAGCCATATAAGTGCACACGATGCACAAAGCGTTTCATTAAAGAAGAACAGTTGACAAATCACTTGTCAAAGCATGACCGAACTTTcaagaagaataaagaaacGGACAGCTCGAAAAGATTCCTTTGCGAAATTTGCTCGAAAAGTTTTACGCAATCGACGACGTTGATTGCACACCTTCGAGCACATAATGGTATAAAACCATACGTTTGCGAAGTTTGTTCGCGACCGTTCACAACTAACGCTTATTTGAAAATGCACATGAGAACGCATACGCAAGAACGACCGTATGTTTGTCAATATTGTTCACGAGCATTTGCTAGAGCCGATACGCTTGCTAATCATTTGACTTCGCATACAGGTGAGGCTAAATATCATTGTAAGTACTGTCCGAAAAACTTCCGTCGTCTGAAGTCGCTCAAAGAACACGTCTTCATTCATACTGGTCAAAGACCTTATGCCTGTCCAACCTGCGATAGACGGTTTAACAACAACGGAAGTCGATACGCTCACAGTAAAAGGTGTAAACAAACTTTTGTTCAGAATCAGAATCGTGCTCAAACACTAACCGCGCAAGTACAGGCTACACCTCAAAATCAACAAAGAGTGCTACAACAGACTACTCTTGAACAAGGACAAATAGTAAAGgcacaaaatattaaaaccatTACTATCACTAAGCCTGAATCAGTTGCCACTCAACAAACGGTTATGCAACTTCAAGAGATATTAATGCCTTTGATCCTTCCTCTTACAGTCACTCTTACGGATGTGGGTGAGGAAGTAATATTACCAGAAGGAACCAAAATATTTACTACATCATAA
Protein Sequence
MEEVIDQTIATEQTSGECLSHEEEDIKVIIDAPINEEMLKHENGDNDSLENISTVEHDYILQQECILSSTNEQEQQQQHHHHQQHQHQHQHPSGESFQREDCTEYVDLLVKAADATTKQEDEDDEEEEKSDITNTPVQPDTDSQCQNETRRSKRKLVRRNFETRRDSDEENYFENLNLSSRLKKGQSSDQSEKIFLCYLCDKEFLSKNVLKEHMHSHEEVRKVLSLKKTPDTPQKNVYNVAKSPPSGKRSNKCPYCGKQYIYITSFSKHLKKHEREKEEGKEESMPLEISFHEDEHSLDLDNYKDARRHLDNEYRKKVKQKEVGPEERRQEERGNEAKRGNNDGGDGGGGGGGGGEGGRGNNNNNNNDDDNHDDDDDDDDDDDDYNDYNDKRQVGNLIKKEEQENRNVRTETFACDKCSEKFYTKRGLQKHAISHVVLSCSICEEEFDSLEKLRNHRAKHVVEGVLTEQELEMDTEYPINKETCDYETEDKDSIDRSHRMENKSIPGLLETENNLSKKNDRNMETHRHSGIDYSCKVCCQRFAMKEMLQKHTEQQHERVKSYKCTQCNKTFGNELTLRNHLIATNHKTFLHGQEYDPNKRIKRVAARAAQKIIDKIKTEDGLEDFDEEEENIDRINRANVIDNNYSRNKREISSHKRHNHKKELECASCNKRCSSKQLLTKHMEQHVKDEQQRVVKSEKQKQSADKKDWQRDYTNEEMYHKENRDDDYDSDFESGLDWPMDNHECPKCKKRYSTKKSLLRHQLLHEEPNFECDICNVKFYRKDKLKAHYDKCSEKNPDQVRKCNICGDTFENNEILREHRSKHVTEGILTEEDLRDIEPRPEEKKPGEKIGRKRRTDIVGLECTECNKQYTSRKGLLRHIQVHEGKKYLCDICPKKFYRREHLKIHVAKHNMIKPYKCTRCTKRFIKEEQLTNHLSKHDRTFKKNKETDSSKRFLCEICSKSFTQSTTLIAHLRAHNGIKPYVCEVCSRPFTTNAYLKMHMRTHTQERPYVCQYCSRAFARADTLANHLTSHTGEAKYHCKYCPKNFRRLKSLKEHVFIHTGQRPYACPTCDRRFNNNGSRYAHSKRCKQTFVQNQNRAQTLTAQVQATPQNQQRVLQQTTLEQGQIVKAQNIKTITITKPESVATQQTVMQLQEILMPLILPLTVTLTDVGEEVILPEGTKIFTTS