Basic Information

Insect: Bombus vancouverensis
Gene Symbol: -
Assembly: GCA_011952275.1
Location: NW:1617984-1625668[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.11 7.1 6.6 2.3 1 23 249 271 249 271 0.94

2 18 0.00084 0.054 13.3 3.1 2 23 306 327 305 327 0.98

3 18 0.00087 0.055 13.2 0.5 1 23 467 489 467 489 0.96

4 18 0.0015 0.094 12.5 0.3 2 23 493 514 492 514 0.96

5 18 0.14 9.1 6.3 3.2 1 23 587 610 587 610 0.94

6 18 0.0003 0.019 14.7 0.7 1 21 616 636 616 640 0.92

7 18 0.0011 0.07 12.9 2.9 2 23 719 740 718 740 0.95

8 18 2e-05 0.0013 18.4 4.1 1 23 797 819 797 819 0.97

9 18 0.0002 0.013 15.3 0.7 1 20 824 843 824 845 0.94

10 18 0.034 2.1 8.2 0.6 2 23 856 877 856 877 0.97

11 18 2e-05 0.0013 18.4 0.6 2 23 916 937 915 937 0.97

12 18 1.8e-05 0.0012 18.5 1.6 1 23 942 964 942 964 0.95

13 18 0.0001 0.0066 16.1 2.9 1 23 970 992 970 992 0.98

14 18 3.3e-06 0.00021 20.9 0.4 1 23 1008 1030 1008 1030 0.95

15 18 2.7e-07 1.7e-05 24.3 0.6 1 23 1036 1058 1036 1058 0.99

16 18 1.6e-05 0.001 18.7 0.2 1 23 1064 1086 1064 1086 0.98

17 18 0.00011 0.0068 16.1 4.1 1 23 1092 1114 1092 1114 0.96

18 18 0.0069 0.44 10.4 0.3 1 20 1120 1139 1120 1141 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.11	7.1	6.6	2.3	1	23	249	271	249	271	0.94
2	18	0.00084	0.054	13.3	3.1	2	23	306	327	305	327	0.98
3	18	0.00087	0.055	13.2	0.5	1	23	467	489	467	489	0.96
4	18	0.0015	0.094	12.5	0.3	2	23	493	514	492	514	0.96
5	18	0.14	9.1	6.3	3.2	1	23	587	610	587	610	0.94
6	18	0.0003	0.019	14.7	0.7	1	21	616	636	616	640	0.92
7	18	0.0011	0.07	12.9	2.9	2	23	719	740	718	740	0.95
8	18	2e-05	0.0013	18.4	4.1	1	23	797	819	797	819	0.97
9	18	0.0002	0.013	15.3	0.7	1	20	824	843	824	845	0.94
10	18	0.034	2.1	8.2	0.6	2	23	856	877	856	877	0.97
11	18	2e-05	0.0013	18.4	0.6	2	23	916	937	915	937	0.97
12	18	1.8e-05	0.0012	18.5	1.6	1	23	942	964	942	964	0.95
13	18	0.0001	0.0066	16.1	2.9	1	23	970	992	970	992	0.98
14	18	3.3e-06	0.00021	20.9	0.4	1	23	1008	1030	1008	1030	0.95
15	18	2.7e-07	1.7e-05	24.3	0.6	1	23	1036	1058	1036	1058	0.99
16	18	1.6e-05	0.001	18.7	0.2	1	23	1064	1086	1064	1086	0.98
17	18	0.00011	0.0068	16.1	4.1	1	23	1092	1114	1092	1114	0.96
18	18	0.0069	0.44	10.4	0.3	1	20	1120	1139	1120	1141	0.89

Sequence Information

Coding Sequence: ATGAATGTAACTTCAGATTTACAGATATCGATATGTAAATTAGGAGCGAAGTTTGAAATCATATGTACCACGTCAATACTTGTATGCAGAAGATGCAAAACACGCATTAGTATTTGCATAGAAAGTCAGAGTGCGAAAGAACAGAACTCGAACGCGGTAATGGAGGAGGTAATCGATCAAACTATCGCTACAGAGCAGACATCGGGAGAGTGCCTGAGTCATGAAGAAGAGGACATTAAAGTAATCATAGATGCTCCCATTAACGAAGAAATGTTAAAACACGAAAACGGGGATAACGATTGccttgaaaatatttcaacggtAGAACACGATTATATATTGCAGCAGGAATGTATATTATCTAGCACGAATGAGCAGgagcagcaacaacagcatCATCATCATCAACAACATCAACATCAACATCAACATCCCTCCGGAGAATCGTTTCAGCGGGAGGATTGCACCGAGTACGTAGATCTATTGGTAAAAGCAGCTGATGCAACGACAAAACAAGAAGATGAGGtggaagatgaagaagaagaaaaatcggatATTACGAACACGGTTGTTCAGCCAGATACAGATTCTCAGTGTCAAAATGAAACGAGAAGAAGCAAACGTAAATTAGTTCGGCGAAATTTTGAAACGAGACGAGATTCCGACGAGGAAAactattttgaaaatttgaatttaagcTCGAGACTGAAAAAAGGTCAGTCCTCTGATCAATCGGaaaaaatttttctatgttaTCTGTGCGACAAAGAGTTTTTGTCGAAGAATGTTTTGAAGGAGCATATGCATTCTCACGAAGAAGTTCGAAAGGTATTGTCTCTGAAAAAAACACCGGATACACCGCAAAAGAACGTTTATAATGTTGCAAAGTCCCCTCCATCGGGTAAGAGATCAAACAAGTGCCCGCATTGTGGCAAgcaatacatatatataaccTCGTTTAGTAAACATTTGAAAAAACatgaaagggagaaagaagagGGCAAGGAAGAATCAATGCCCTTAGAAATATCATTCCACGAAGACGAACATAGTCTAGatcttgataattataaagaTGCACGTCGGCATTTGGATAACGAGTATCGGAAAAAAGTCAAACAAAAAGAGGTGGGTCCAGAAGAGCatagagaggaagaaaaagggaaCGAGGCGAAAAGAGGCAATAACGGTGGCGgtgatggtggtggtggtgatgGCGGCGGCGGCGAAGGAGGAGGAGCAGCAggaaataacaacaataacaacaaTGATGATGACAaccacgacgacgacgacgatgacgacgacgatgaaTACAATGACTACGACGATAAAAGACAAGTGGgtaatttgattaaaaaagaggaacaggagAATCGCAATGTCCGTACAGAAACGTTTGCATGCGACAAGTGTGCagagaaattttatacaaaacgtGGCTTACAAAGGCATGCGATTTCGCATGTTGTTCTCAGTTGCAGTATATGCGAAGAAGAATTCGATTCActggaaaaattaagaaatcatCGCGCGAAACACGTGGTTGAAGGTGTTCTAACTGAACAAGAACTTGAGATGGATGCAGAGTATTCAATTAGTAAGGAAACGTGTGATTACGAGACAGAGGATAAAGATAGCATAGACAGGAATCACAGGATGGAAAACAAATCAATACCAGGATTGCTggaaacagaaaataatttatcgaagaaaaatgataGAAACATGGAGACCCATCGTCATTCGGGGATTGACTATAGTTGCAAGGTGTGTTGCCAACGATTTGCAATGAAAGAAATGTTGCAAAAACATACGGAACAGCAACATGAACGTGTAAAAACTTACAAGTGCACACAATGTAACAAAACATTTGGTAACGAACTTACTTTACGCAATCATCTTATAGCTACTAATCATAAAACTTTCCTTCATGGACAAGAATATGACCCTAATAAACGTATTAAAAGAGTTGCTGCGAGAGCTGCACaaaaaattatcgataaaattaaaaccGAGGATGGTTTGGAAGATTTCGACGAGGAAGAGGAGAATATCGATAGAATTAATCGCGCTAATGTTACAGATAATAATTATAGTCGGAATAAGCGAGAAATATCCTCGCATAAGAGACATAATCATAAGAAGGAATTGGAATGTGCGAGTTGTAATAAAAGATGCAGTTCAAAGCAATTGTTAACAAAACATATGGAGCAACATGTAAAAGACGAGCAACAACGAGTGGTCAAGTCGGAAAAGCAAAAGCAATCGGCAGATAAGAAAGATTGGCAAAGGGACTACGCTAATGAGGAGATGTACCATAAAGAGAATAGAGATGACGATTATGATTCGGATTTTGAAAGTGGTTTGGATTGGCCAATGGATAATCACGAGTGCCCGAAGTGTAAAAAACGATACAGCACGAAAAAATCATTGTTACGTCATCAATTGTTGCACGAAGAACCGAATTTCGAATGCGATATTTGCAATGTTAAGTTTTACCGCAAAGACAAACTAAAAGCCCATTATGATAAGTGTTCGGAGAAGAACCCCGATCAAGTGAGAAAGTGCAATATCTGCGGAGACACGTTTGAGAACAATGAGATTCTGCGAGAACATAGATCGAAACATGTTACCGAAGGCATTCTTACGGAAGAAGACCTGAGAGATATCGAACCGCGACCCGAGGAGAAAAAACCAGGTGAAAAGATTGGTAGGAAGAGAAGGACTGATATCGTAGGTTTAGAGTGCACGGAATGTAACAAGCAATATACATCGAGAAAAGGGCTTTTACGACATATTCAAGTCCACGAAGGAAAAAAGTATCTGTGTGATATATGTccaaaaaaattttatagaaggGAACATTTAAAGATACACGTAGCTAAACATAACATGATTAAGCCATATAAGTGCACACGATGCACAAAGCGTTTCATTAAAGAGGAACAGTTGACAAATCATTTGTCAAAGCATGACCGAACTTTCAAGAAGAATAAAGAAACGGACAGCTCGAAAAGATTCCTTTGTGAAATTTGTTCGAAAAGTTTTACGCAATCGACGACGTTGATTGCACACCTTCGAGCACATAATGGTATAAAACCATACGTTTGCGAAGTTTGTTCGCGACCGTTCACAACTAACGCTTATTTGAAAATGCACATGAGAACGCATACCCAAGAACGACCGTATGTTTGTCAATATTGTTCACGAGCATTTGCTAGAGCCGATACGCTTGCTAATCATTTGACTTCGCATACAGGCGAGGCTAAATACCATTGTAAGTACTGTCCGAAAAACTTCCGTCGTCTGAAGTCGCTCAAAGAACACGTCTTCATTCATACTGGTCAAAGACCTTATGCCTGTCCAACCTGCGATAGACGGTTTAACAACAACGGAAGTCGATACGCTCATAGTAAAAGGTGTAAACAAACTTTTGTTCAGAATCAAAATCGTGCTCAAACACTAACCGCGCAAGTACAGGCTACGCCTCAAAATCAACAAAGAGTGCTACAACAGACTACTCTTGAACAAGGACAAATAGTAAAGGCACAGAATATTAAAACCATTACTATCACTAAACCTGAATCAGTCGCCACTCAACAAACAGTTATGCAACTTCAAGAGATATTAATGCCTTTGATCCTTCCTCTTACAGTCACTCTTACGGATGTCGGTGAGGAAGTAATATTACCAGAAGGAACCAAAATATTTACTACATCATAA
Protein Sequence: MNVTSDLQISICKLGAKFEIICTTSILVCRRCKTRISICIESQSAKEQNSNAVMEEVIDQTIATEQTSGECLSHEEEDIKVIIDAPINEEMLKHENGDNDCLENISTVEHDYILQQECILSSTNEQEQQQQHHHHQQHQHQHQHPSGESFQREDCTEYVDLLVKAADATTKQEDEVEDEEEEKSDITNTVVQPDTDSQCQNETRRSKRKLVRRNFETRRDSDEENYFENLNLSSRLKKGQSSDQSEKIFLCYLCDKEFLSKNVLKEHMHSHEEVRKVLSLKKTPDTPQKNVYNVAKSPPSGKRSNKCPHCGKQYIYITSFSKHLKKHEREKEEGKEESMPLEISFHEDEHSLDLDNYKDARRHLDNEYRKKVKQKEVGPEEHREEEKGNEAKRGNNGGGDGGGGDGGGGEGGGAAGNNNNNNNDDDNHDDDDDDDDDEYNDYDDKRQVGNLIKKEEQENRNVRTETFACDKCAEKFYTKRGLQRHAISHVVLSCSICEEEFDSLEKLRNHRAKHVVEGVLTEQELEMDAEYSISKETCDYETEDKDSIDRNHRMENKSIPGLLETENNLSKKNDRNMETHRHSGIDYSCKVCCQRFAMKEMLQKHTEQQHERVKTYKCTQCNKTFGNELTLRNHLIATNHKTFLHGQEYDPNKRIKRVAARAAQKIIDKIKTEDGLEDFDEEEENIDRINRANVTDNNYSRNKREISSHKRHNHKKELECASCNKRCSSKQLLTKHMEQHVKDEQQRVVKSEKQKQSADKKDWQRDYANEEMYHKENRDDDYDSDFESGLDWPMDNHECPKCKKRYSTKKSLLRHQLLHEEPNFECDICNVKFYRKDKLKAHYDKCSEKNPDQVRKCNICGDTFENNEILREHRSKHVTEGILTEEDLRDIEPRPEEKKPGEKIGRKRRTDIVGLECTECNKQYTSRKGLLRHIQVHEGKKYLCDICPKKFYRREHLKIHVAKHNMIKPYKCTRCTKRFIKEEQLTNHLSKHDRTFKKNKETDSSKRFLCEICSKSFTQSTTLIAHLRAHNGIKPYVCEVCSRPFTTNAYLKMHMRTHTQERPYVCQYCSRAFARADTLANHLTSHTGEAKYHCKYCPKNFRRLKSLKEHVFIHTGQRPYACPTCDRRFNNNGSRYAHSKRCKQTFVQNQNRAQTLTAQVQATPQNQQRVLQQTTLEQGQIVKAQNIKTITITKPESVATQQTVMQLQEILMPLILPLTVTLTDVGEEVILPEGTKIFTTS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00215850;
90% Identity: iTF_00229494;
80% Identity: iTF_00214523;