Bdif017556.1
Basic Information
- Insect
- Bombus difficillimus
- Gene Symbol
- -
- Assembly
- GCA_014737525.1
- Location
- JACXIT010000005.1:742076-745758[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 18 0.12 11 6.8 2.3 1 23 154 176 154 176 0.94 2 18 0.00029 0.027 15.1 1.4 2 23 211 232 210 232 0.98 3 18 0.0013 0.12 13.0 0.6 1 23 295 317 295 317 0.96 4 18 0.0016 0.15 12.7 0.3 2 23 321 342 320 342 0.96 5 18 0.15 14 6.5 3.2 1 23 415 438 415 438 0.94 6 18 0.00032 0.03 14.9 0.7 1 21 444 464 444 468 0.92 7 18 0.0012 0.11 13.2 2.9 2 23 547 568 546 568 0.95 8 18 2.1e-05 0.002 18.6 4.1 1 23 625 647 625 647 0.97 9 18 0.00021 0.02 15.5 0.7 1 20 652 671 652 673 0.94 10 18 0.036 3.4 8.5 0.6 2 23 684 705 684 705 0.97 11 18 2.2e-05 0.002 18.6 0.6 2 23 744 765 743 765 0.97 12 18 2e-05 0.0019 18.7 1.6 1 23 770 792 770 792 0.95 13 18 0.00011 0.01 16.4 2.9 1 23 798 820 798 820 0.98 14 18 3.5e-06 0.00033 21.1 0.4 1 23 836 858 836 858 0.95 15 18 2.9e-07 2.7e-05 24.5 0.6 1 23 864 886 864 886 0.99 16 18 1.7e-05 0.0016 18.9 0.2 1 23 892 914 892 914 0.98 17 18 0.00011 0.011 16.3 4.1 1 23 920 942 920 942 0.96 18 18 0.0075 0.7 10.6 0.3 1 20 948 967 948 969 0.89
Sequence Information
- Coding Sequence
- ATGGAGGAGGTAATCGATCAAACTATCGCTACAGAGCAGACATCGGGAGAGTGCCTGAGTCATGAAGAAGAGGACATTAAAGTAATCATAGATGCTCCCATTAACGAAGAAATGTTAAAACACGAAAACGGGGATAACGATTGCCTTGAAAATATTTCAACGCGGGAGGATTGCACTGAGTACGTAGATCTATTGGTAAAAGCAGCTGATGCAACGACAAAACAAGAAGATGAGGAGGAAGATGAAGAAGAAGAAGAAGAAAAATCGGATATTACGAACACGGTTGTTCAGCCAGATGCAGATTCTCAGTGTCAAAATGAAACGAGGAGAAGCAAACGTAAATTAGTTCGGCGAAATTTTGAAACGAGACGAGATTCCGACGAGGAAAACTATTTTGAAAATTTGAATTTAAGCTCGAGACTGAAAAAAGGTCAGTCCTCTGATCAATCGGAAAAAATTTTTCTATGTTATCTGTGCGACAAAGAGTTTTTGTCGAAGAATGTTTTAAAGGAGCATATGCACTCTCACGAAGAAGTTCGAAAGGTATTGTCTCTGAAAAAAACACCGGATACACCGCAAAAGAACGTTTATAATGTTACGAAGTCTCCTCCATCGGGTAAGAGATCAAACAAGTGCCCGTATTGTGGCAAGCAGTACATATATATAACCTCGTTTAGTAAACATTTGAAAAAACATGAAAGGGAGAAAGAAGAGGGCAAGGAAGAATCAATGCCCTTAGAAATATCATTCCACGAAGACGAACATAGTCTAGATCTTGATAATTATAAAGATGCACGTCGGCATTTGGATAACGAGTATCGGAAAAAAGTGAAACAAAAAGAGGTGGAGGAACAGGAGAATCGCAATGTCCGTACAGAAACGTTTGCATGCGACAAATGCGCAGAGAAATTTTATACAAAACGTGGCTTACAAAAACATGCGATTTCGCATGTTGTTCTCAGTTGCAGCATATGCGAAGAAGAATTCGATTCACTGGAAAAATTAAGAAACCACCGCGCGAAGCACGTAGTTGAAGGTGTTCTAACTGAACAAGAACTTGAGATGAATACAGAGTATCCAATTAACAAGGAAACGTGTGATTACGAGACAGAGGATAAAGATAGCATAGACAGGAATCATAGGATGGAAAACAAATCAATACCAGGATTGCTGGAGACAGAAAATAATTTATCGAAGAAAAATGATAGAAACATGGAGACCCATCGTCATTCGGGGATTGACTATAGTTGCAAGGTGTGTTGCCAAAGATTTGCAATGAAAGAAATGTTGCAAAAACACACGGAACAGCAACATGAACGTGTAAAAACTTACAAGTGCACACAATGTAACAAAACATTTGGTAACGAACTTACTTTACGCAATCATCTTATAGCTACTAATCATAAAACTTTTCTTCATGGGCAAGAATATGACCCTAATAAACGTATTAAAAGAGTTGCTGCGAGAGCAGCACAAAAAATTATCGATAAAATTAAAACCGAGGATGGTTTGGAAGATTTCGACGAGGAAGAGGAGAATACCGATAGAATTAATCGCGCTAATGTTACAGATAATAATTATAGTCGGAATAAGCGAGAAATATCCTCGCATAAGAGACATAATCATAAGAAAGAATTGGAATGTGCGAGTTGCAATAAAAGATGCAGTTCAAAGCAATTGTTAACAAAACATATGGAACAACATGTAAAAGACGAGCAACAACGAGTGGTCAAGTCGGAAAAGCAAAAGCAATCGGCAGATAAGAAAGATTGGCAAAGGGACTACGCTAATGAGGAGATGTACCATAAGGAGAATAGAGATGACGATTATGATTCGGATTTCGAAAGTGGTTTGGATTGGCCAATGGATAATCACGAGTGCCCAAAGTGTAAAAAACGATACAGCACGAAAAAATCATTGTTACGTCATCAATTGTTGCACGAAGAACCGAATTTCGAATGCGATATTTGTAATGTTAAGTTTTACCGCAAAGACAAACTAAAAGCCCATTATGATAAGTGTTCGGAGAAGAACCCCGATCAAGTGAGAAAGTGCAATATCTGCGGAGACACGTTTGAGAACAATGAGATTTTGCGAGAACATAGATCAAAACATGTTACCGAAGGCATTCTTACGGAAGAAGACCTGAGAGATATCGAACCGCGACCCGAGGAGAAAAAGCCAGGTGAAAAGATTGGTAGAAAGAGAAGGACTGATATCGTAGGTTTAGAGTGCACGGAATGTAACAAGCAATATACATCGAGAAAAGGGCTTTTACGACATATTCAAGTCCATGAAGGAAAAAAGTATCTGTGTGATATATGTCCAAAAAAATTTTATAGAAGGGAACATTTAAAGATACACGTAGCTAAACATAACATGATTAAGCCATATAAGTGCACACGATGCACAAAGCGTTTCATTAAAGAAGAGCAGTTGACAAATCACTTGTCAAAGCATGACCGAACTTTCAAGAAGAATAAAGAAACGGACAGCTCGAAAAGATTCCTTTGCGAAATTTGCTCGAAAAGTTTTACGCAATCGACAACGTTGATTGCACACCTTCGAGCACATAATGGTATAAAACCATACGTTTGCGAAGTTTGTTCGCGACCGTTCACAACTAACGCTTATTTGAAAATGCACATGAGAACGCATACGCAAGAACGACCGTATGTTTGTCAATATTGTTCACGAGCATTTGCTAGAGCCGATACGCTTGCTAATCATTTGACTTCGCATACAGGTGAGGCTAAATATCATTGCAAGTATTGTCCGAAAAACTTCCGTCGTCTGAAGTCGCTCAAGGAACACGTCTTCATTCATACTGGTCAAAGACCTTATGCCTGTCCAACCTGCGATAGACGGTTTAACAACAACGGAAGTCGATACGCTCACAGCAAAAGGTGTAAACAAACTTTTGTTCAGAATCAAAATCGTGCACAAACACTAACCGCGCAAGTACAGGCTACGCCTCAAAATCAACAAAGAGTGCTACAACAGACTACTCTTGAACAAGGACAAATAGTAAAGGCACAAAATATTAAAACCATTACTATCACTAAACCAGAATCAGTCGCCACTCAACAAACGGTTATGCAACTTCAAGAGATATTGATGCCTTTGATCCTTCCTCTTACAGTCACTCTTACGGACGTTGGTGAGGAAGTAATATTACCAGAAGGAACCAAAATATTTACTACATCATAA
- Protein Sequence
- MEEVIDQTIATEQTSGECLSHEEEDIKVIIDAPINEEMLKHENGDNDCLENISTREDCTEYVDLLVKAADATTKQEDEEEDEEEEEEKSDITNTVVQPDADSQCQNETRRSKRKLVRRNFETRRDSDEENYFENLNLSSRLKKGQSSDQSEKIFLCYLCDKEFLSKNVLKEHMHSHEEVRKVLSLKKTPDTPQKNVYNVTKSPPSGKRSNKCPYCGKQYIYITSFSKHLKKHEREKEEGKEESMPLEISFHEDEHSLDLDNYKDARRHLDNEYRKKVKQKEVEEQENRNVRTETFACDKCAEKFYTKRGLQKHAISHVVLSCSICEEEFDSLEKLRNHRAKHVVEGVLTEQELEMNTEYPINKETCDYETEDKDSIDRNHRMENKSIPGLLETENNLSKKNDRNMETHRHSGIDYSCKVCCQRFAMKEMLQKHTEQQHERVKTYKCTQCNKTFGNELTLRNHLIATNHKTFLHGQEYDPNKRIKRVAARAAQKIIDKIKTEDGLEDFDEEEENTDRINRANVTDNNYSRNKREISSHKRHNHKKELECASCNKRCSSKQLLTKHMEQHVKDEQQRVVKSEKQKQSADKKDWQRDYANEEMYHKENRDDDYDSDFESGLDWPMDNHECPKCKKRYSTKKSLLRHQLLHEEPNFECDICNVKFYRKDKLKAHYDKCSEKNPDQVRKCNICGDTFENNEILREHRSKHVTEGILTEEDLRDIEPRPEEKKPGEKIGRKRRTDIVGLECTECNKQYTSRKGLLRHIQVHEGKKYLCDICPKKFYRREHLKIHVAKHNMIKPYKCTRCTKRFIKEEQLTNHLSKHDRTFKKNKETDSSKRFLCEICSKSFTQSTTLIAHLRAHNGIKPYVCEVCSRPFTTNAYLKMHMRTHTQERPYVCQYCSRAFARADTLANHLTSHTGEAKYHCKYCPKNFRRLKSLKEHVFIHTGQRPYACPTCDRRFNNNGSRYAHSKRCKQTFVQNQNRAQTLTAQVQATPQNQQRVLQQTTLEQGQIVKAQNIKTITITKPESVATQQTVMQLQEILMPLILPLTVTLTDVGEEVILPEGTKIFTTS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00215850;
- 90% Identity
- iTF_00219938;
- 80% Identity
- -