Esub007635.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Eupithecia subumbrata
Gene Symbol
-
Assembly
GCA_949316285.1
Location
OX438634.1:9905731-9927761[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 21 0.0001 0.0086 17.4 2.2 1 23 414 436 414 436 0.97
2 21 0.00035 0.03 15.7 1.0 1 20 442 461 442 464 0.94
3 21 0.00086 0.074 14.5 5.6 1 23 483 505 483 505 0.98
4 21 0.00012 0.01 17.1 4.1 1 23 511 533 511 533 0.99
5 21 4.6e-05 0.004 18.5 5.3 1 23 539 561 539 561 0.97
6 21 6.6e-06 0.00056 21.1 8.4 1 23 567 589 567 589 0.97
7 21 2.9e-06 0.00025 22.2 3.0 1 23 595 617 595 617 0.97
8 21 0.00013 0.011 17.1 6.7 1 23 623 645 623 645 0.97
9 21 2.4e-05 0.0021 19.3 6.4 1 23 651 673 651 673 0.98
10 21 0.00077 0.066 14.6 0.5 1 16 679 694 679 695 0.97
11 21 6.1 5.2e+02 2.3 0.5 6 23 717 734 715 734 0.96
12 21 6.2e-05 0.0053 18.1 7.9 1 23 740 762 740 762 0.98
13 21 0.00016 0.014 16.7 6.8 1 23 768 790 768 790 0.97
14 21 5.1e-06 0.00044 21.5 5.6 1 23 796 818 796 818 0.98
15 21 2.2e-05 0.0019 19.5 6.7 1 23 824 846 824 846 0.97
16 21 4.3e-06 0.00037 21.7 5.2 1 23 852 874 852 874 0.98
17 21 2.4e-06 0.0002 22.5 3.6 2 23 881 902 880 902 0.98
18 21 2.2e-05 0.0019 19.5 8.1 1 23 908 930 908 930 0.97
19 21 2.1e-06 0.00018 22.7 6.5 1 23 936 958 936 958 0.98
20 21 0.00056 0.048 15.0 0.3 1 23 965 987 965 987 0.97
21 21 0.46 40 5.9 5.7 1 23 997 1019 997 1019 0.98

Sequence Information

Coding Sequence
ATGAATCCCGAGCATCATAATATCAATACGGGCGGGGGCCAACCTCCTGGGAGTTCGGAGTCTCAGAATCAAAGAGTTCAAGCTCAGCAGCAGCAACAGCAAGTAAGCCTGCCTGCCTCCACGTCTGCCACCGACTTGCGAGTCAACTCGGCTGCTGTGAACGTTGCTTTGTCCAGTGTTGCTAAGTACTGGGTATTTACGAATTTATTCCCCGGACCTATTCCTCAAGTGTCCGTCTACGGGCTTCCAACTGGGACAAGAATTGAAAATGGAAAAGCTGTTCAGgATATCGGACAAGCACATGCAAGTATACTCAATGGGGATCCAAACATCATTCTCGGGCATCACGGAGGACAGTCCCAGGTCTCAGTATCTGCGGCCCAACAGATACCTGTCTCCCAAATCATTGCCACACAGTCTGGGCAGACACATGAAGCATTGGTGGCACACAGTCAACAGCAAGAACTACAGCCTTCCAACCAGGTCCCCACATCGCATCACCAGGTACCCACTAACCGGGTCGAATTTGTCCAACACCATAACATTGATATGGGGCATCATTCTCAACAACAACACCTAATGCAGCAGCAGCTTATGGCAGCCTCAAGGCCAGAACACTCAAACCAACAGATTCAACTGACTGTCAGTGAAGACGGCATCGTGACGGTAGTAGAACCAGGCAGCAGTAAAATGGCTGAGAAGGAAGAGATGCACGAGGCGATCAAGCTACCGTCGGATCATACACTCACTGTACATCAGTTGCAGCAGATTGTCGGACAACAGGTGCTAGACAGCGTGGTTCGCATCGAGCAAGCGACCGGCGAACCAGCTAACATCCTAGTCACCCACAACCCTGACGGCACCACGTCCATCGAAGCCAGTGCTAGCGATCCGCTAGCTATCGTCAAAGATGAGAAGAATCAAGGGAAGATTGAGTCGGCGCAGTTCGCTATACCGGCTGAGATCAAGGAAATGAAGGGCATTGATTTAAAGTCCGTCAACGCCATGAACATGGAAGGTGCCGTAGTGAAGATATCAACGGGTGCGCCAGAACACGATCTCCACGCAATGTACAAAGTAAACGTCGAGGATCTGTCACAGCTGCTGGCGTACCACGAAGTCTTCGGGAAAATGGGGCCCGATGGACAGCCTCAGGCTAAAGTCTCTGTAGGCGATGTAGAAATTGAAGTGCCTGGAACGAGTGCCGGTATGTCCGAAGCAGAGAACTCGCCCGGACACCATTCCTGTGATATCTGCGGGAAAATATTCCAATTCCGGTATCAGCTCATCGTACACAGACGTTACCACGGCGAGACCAAGCCATTCACATGCCAAGTTTGCGGCACCTCATTCGCGAACCCCGTAGAACTATCTCGGCACGGGAAGTGCCATTTGGCAGGTGACCCAGCTGAAAGACACGCAAAGAGAATGGCCCAAGACAAACCTTATGCATGCTCCACTTGCCATAAAACATTCTTGCGTAAGGAGCATCTAAACAACCATGTACGCAGTCACACGGGAGAAACTCCATACAGATGCGAGTTCTGCGCCAAAACATTCACCCGGAAAGAGCACATGGTAAACCACGTGCGGAAACATACGGGAGAGACGCCTCATCGCTGTGATATCTGCAAGAAGAGCTTTACAAGGAAGGAGCATTTTATGAACCATGTTATGTGGCACACAGGAGAAACGCCGCACCATTGTACCATTTGTGGGAAGAAATATACTAGGAAGGAACATTTGACGAATCATATGAGATCGCACACGAACGATACCCCGTTCCGCTGTGAACAGTGCGGAAAATCCTTCACGAGAAAAGAGCATTACTCCAATCACATTTTGTGGCACACTGGCGAAACCCCTCACCGCTGCGACTTCTGCTCAAAAACCTTCACCCGCAAGGAGCATCTCTTAAACCACGTGAGACAACACACGGGAGAGTCGCCGCATCGCTGCAACTACTGCTCCAAGTCGTTCACGCGTCGCGAGCACCTCGTCAACCACGTGCGACAACACACGGGGGAGACGCCTTTCCAATGCGGATACTGTCCTAAAGCATTTACTAGGAAAGACCATTTAGGTGAGTTACTACTACAACACGGGAGAGTCGCCGCATCGCTGCAACTACTGCTCGCAAGTCGTTCATGCGGCGCGAGCACCTCGAAAGACCATTTATTAGTAAACCACGTACGACAACACACCGGTGAATCTCCCCACAAGTGCTCGTTCTGCACGAAATCCTTCACTCGCAAGGAGCACCTCACGAACCACGTGAGGCAACACACGGGCGAGTCACCCCATCGGTGTACATTCTGCGCTAAGTCTTTCACGAGGAAAGAACATCTAACCAATCACGTCAGACAGCATACGGGCGAAACGCCACACAAGTGCACGTATTGCCCGCGCGCGTTTTCGCGAAAGGAGCATCTGAACTCGCACCTGCGGCAGCACACGGGCGTCACTCCGCACTCCTGCTCGTACTGCAGTAAGACCTTCACGAGGAAGGAGCACCTCGTCAACCACGTACGGAAACACACTGGCGAAACACCGTTCAAGTGCACGTTCTGTTCGAAGTCATTTTCGCGCAAGGAGCATCTAACGAATCACATAAATCTGCACACGGGGGAGACACCGAACAAATGTCCATTCTGCACTAAATCCTTCTCTAGGAAGGAACATCTTACGAACCATGTCAGAATACACACAGGCGAGTCGCCGCACCGCTGTGATTTCTGCCAGAAAACGTTCACTCGCAAGGAACATTTGACGAACCATATGAAACAGCACACGGGTGGCGCTGCTCACACGTGTAAGATTTGCCAGAAACCATTCACAAGGAAAGAACATCTACAGACGCATATGAGGTACCACAGTTGTAACGACCGACCGTTCAGTTGTGGAGAATGCGGCAAATCCTTCCCACTGAAGGGAAATCTCATGTTCCACGAGCGGTCTCACAACAAATCCGGAGGAGTCCCGAGGCCTTTCCGCTGCGATATCTGTTCCAAGGACTTTTTGTGCAAATCTCATTTACTAACTCACCGGCGGGTACACGAGGACGCCGGCGACGAAGCCTCGGTAGAGACGCAGACAGAGAATGAAGAGTGCTTGACCGTCACCACAGATTGCACTAATAAATGCATCAAGGTGGAGCTTGACACGGCAGAACAAAGAACTTCTGTTGAAAATGGAACAACCGAAAATATTGTAGTGCAGCCTGCACTTGATTCCCCGAACCACATAGTAGTCACCCAAACTCAAAACACTGTGATGCAGATAAGCAGTCAACAGGTGCGGGTAGGGTCATCAAGTCCAACTGGTGTAACCACGGGCACTTTCACCCACACGGTGAGCGCACAACACCATCCAGGTTCCACGATCGCGCACCACCCGGTTACTGTGAACTACTAG
Protein Sequence
MNPEHHNINTGGGQPPGSSESQNQRVQAQQQQQQVSLPASTSATDLRVNSAAVNVALSSVAKYWVFTNLFPGPIPQVSVYGLPTGTRIENGKAVQDIGQAHASILNGDPNIILGHHGGQSQVSVSAAQQIPVSQIIATQSGQTHEALVAHSQQQELQPSNQVPTSHHQVPTNRVEFVQHHNIDMGHHSQQQHLMQQQLMAASRPEHSNQQIQLTVSEDGIVTVVEPGSSKMAEKEEMHEAIKLPSDHTLTVHQLQQIVGQQVLDSVVRIEQATGEPANILVTHNPDGTTSIEASASDPLAIVKDEKNQGKIESAQFAIPAEIKEMKGIDLKSVNAMNMEGAVVKISTGAPEHDLHAMYKVNVEDLSQLLAYHEVFGKMGPDGQPQAKVSVGDVEIEVPGTSAGMSEAENSPGHHSCDICGKIFQFRYQLIVHRRYHGETKPFTCQVCGTSFANPVELSRHGKCHLAGDPAERHAKRMAQDKPYACSTCHKTFLRKEHLNNHVRSHTGETPYRCEFCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHFMNHVMWHTGETPHHCTICGKKYTRKEHLTNHMRSHTNDTPFRCEQCGKSFTRKEHYSNHILWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCNYCSKSFTRREHLVNHVRQHTGETPFQCGYCPKAFTRKDHLGELLLQHGRVAASLQLLLASRSCGASTSKDHLLVNHVRQHTGESPHKCSFCTKSFTRKEHLTNHVRQHTGESPHRCTFCAKSFTRKEHLTNHVRQHTGETPHKCTYCPRAFSRKEHLNSHLRQHTGVTPHSCSYCSKTFTRKEHLVNHVRKHTGETPFKCTFCSKSFSRKEHLTNHINLHTGETPNKCPFCTKSFSRKEHLTNHVRIHTGESPHRCDFCQKTFTRKEHLTNHMKQHTGGAAHTCKICQKPFTRKEHLQTHMRYHSCNDRPFSCGECGKSFPLKGNLMFHERSHNKSGGVPRPFRCDICSKDFLCKSHLLTHRRVHEDAGDEASVETQTENEECLTVTTDCTNKCIKVELDTAEQRTSVENGTTENIVVQPALDSPNHIVVTQTQNTVMQISSQQVRVGSSSPTGVTTGTFTHTVSAQHHPGSTIAHHPVTVNY