Dmen025759.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Diaphora mendica
Gene Symbol
-
Assembly
GCA_949125395.1
Location
OX421321.1:18181714-18207995[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 20 8.9e-05 0.012 17.4 2.2 1 23 422 444 422 444 0.97
2 20 0.0046 0.63 12.0 0.6 1 20 450 469 450 472 0.94
3 20 1.2e-05 0.0016 20.2 5.8 1 23 491 513 491 513 0.98
4 20 0.00011 0.015 17.2 4.1 1 23 519 541 519 541 0.99
5 20 4.1e-05 0.0056 18.5 5.3 1 23 547 569 547 569 0.97
6 20 1.1e-05 0.0014 20.4 7.9 1 23 575 597 575 597 0.97
7 20 8.3e-07 0.00011 23.8 2.9 1 23 603 625 603 625 0.97
8 20 0.00011 0.015 17.1 6.7 1 23 631 653 631 653 0.97
9 20 0.00015 0.021 16.7 6.7 1 23 659 681 659 681 0.97
10 20 5.4e-07 7.3e-05 24.4 1.9 1 23 687 709 687 709 0.98
11 20 5.5e-05 0.0075 18.1 7.9 1 23 715 737 715 737 0.98
12 20 4.6e-05 0.0061 18.4 6.8 1 23 743 765 743 765 0.98
13 20 1.1e-05 0.0015 20.3 4.4 1 23 771 793 771 793 0.98
14 20 8.2e-06 0.0011 20.7 6.0 1 23 799 821 799 821 0.97
15 20 1.8e-06 0.00024 22.8 4.1 1 23 827 849 827 849 0.98
16 20 3.4e-06 0.00046 21.9 6.0 1 23 855 877 855 877 0.98
17 20 2.9e-05 0.0039 19.0 7.7 1 23 883 905 883 905 0.97
18 20 1.7e-05 0.0023 19.7 6.3 1 23 911 933 911 933 0.96
19 20 0.0013 0.18 13.8 0.9 1 23 940 962 940 962 0.96
20 20 0.019 2.6 10.1 5.3 1 23 972 994 972 994 0.99

Sequence Information

Coding Sequence
ATGAATCCTGAACACCATAGTATGACCACGGGTGGTGGCCAACCTCCGGGAAGTTCTGAGTCTCAGAATCAAAGAATTCAATCTGCTCAGCAACAACAGCAAAATAACTTGCCTGCCACGACATCTGCTACTGATCTGCGAGTGAACTCGGTGAACTCTGCTGTGAACGTCGCTTTGTCCAGTGTCGCAAAATATTGGgtgtttacaaatttatttcctGGACCTATACCACAAGTATCAGTATATGGATTACCTGCTGGTGCTCGAATTGAAAACGGAAAACCTGTAcagGATCTTGGTCAAGCTCATGCAAGCATACTCAATGGAGATCCAAATATTATACTTGGCCACCATGCCGGCCAATCTCAAGTCACAGTGTCAGCTGCAGGAGGTCAGCAGATACCAGTATCCCAGATCATTGCTACTCAGTCCGGTCAAACACATGAAGCTCTTGTGGCTCACAGTCATCAAGCAGAACTGGTTGCAGCTCAGAGCAACAACAACAATGCACAGGTGTCAGTTACTACAGACCAACAAACCCATCAGCAGGTACCCACTAATCGGGTCGAGTTTGTACAACACCATAACATTGATATGGGACACCATTCACAACAACACCTTATGCAGCAACAACTCATGGCTACAGCACGTCCGGAGCATAGCAATCAGCAGATACAACTGACAGTGAGCGAAGATGGTATCGTGACTGTAGTAGAACCGGCTGGCAGTAAGCTGGTCGACAAGGAAGAACTCCATGAGGCTATCAAGATGCCTGGCGATCATGGGCTAACTGTACATCAATTACAGCAATTAGTTGGACAACAGGTGATAGACAGCGTAGTTCGCATAGAGCAAGCTACTGGTGAGCCAGCCAACATACTAGTGACACACAACCCTGATGGTACGACGTCAATAGAAGCGGAGTCTCTTATTGTTAAGGACGAAAAGAACTCTTCAAAGATGGAAACCGCACAGTTTGCGATACCGACAGAAATTAAGGAAATCAAAGGCATAGATTTAAAGAATGTGGGGACAATGGGAATGGAAGGTGCTGTTGTCAAGATCTCAGCCGGAGCGTCAGAACACGATCTTCATGCTATGTACAAAGTCAATGTGGAGGATCTCTCACAGTTACTAGCTTACCATGAAGTGTTTGGAAAGTTAAATGCTGATGGACAACAGCAAGCTAAggtTATAACCGAAGTTGAAGTAGAACCAGGTACGAGCGCTACGATGTCAGAAGCAGAATCATCGCCTGGCCATCATTCTTGTGACATTTGCGGCAAAATATTCCAATTTCGATATCAACTCATCGTTCAtagaCGCTATCATGGCGAAAGTAAACCGTTTACATGTCAAGTTTGCGGTTCAGCTTTTGCTAATCCCGTAGAACTATCAAGACACGGAAAGTGCCATCTTGcaGGAGATCCTAATGAAAGGCATGCTAAAAGAATGGCACAAGATAAGCCATATGTCTGTACTACTTGCCACAAAACATTTTCAAGAAAGGAACACTTAGACAATCACGTTCGGAGTCATACTGGAGAGACGCCTTACAGATGTGAGTTCTGCGCAAAAACTTTTACCCGCAAAGAGCACATGGTGAACCACGTACGTAAACACACGGGAGAAACGCCACATCGCTGCGATATCTGCAAGAAGAGTTTTACGAGAAAAGAACATTTCATGAACCATGTCATGTGGCATACAGGTGAAACGCCGCACCATTGTCAAATATGCGGCAAGAAGTATACTAGGAAGGAGCATTTAATGAATCATATGAGGTCTCATACAAATGATACTCCCTTCCGGTGCGATCTGTGCGGCAAATCGTTCACAAGAAAGGAACACTTCACCAATCACATATTGTGGCATACGGGTGAAACACCACATCGCTGTGATTTCTGTTCGAAAACATTTACACGTAAGGAACACTTATTAAACCATGTTCGTCAGCACACTGGCGAGTCACCACACAGATGTACTTTCTGCAGTAAATCTTTCACTCGGCGAGAACATCTAGTTAACCATGTACGGCAGCATACGGGTGAAACTCCCTTCCAGTGTGGATATTGCCCTAAAGCATTCACCAGAAAGGATCATCTTGTAAACCACGTTCGGCAGCATACAGGAGAATCTCCACACAAGTGTTCGTTCTGCACCAAGTCGTTTACCCGTAAAGAGCATTTGACGAACCACGTGCGACAGCACACCGGCGAGTCACCGCATCGATGTACTTTCTGCGCCAAATCTTTCACAAGAAAAGAACATCTAACTAATCATATCAGACAGCACACGGGTGAAACGCCACACAAGTGCACGTTCTGTCCGCGCGCGTTCGCTCGCAAGGAGCACCTCAACAACCACATCCGCCAGCACACGGGCGTCACGCCGCACTCCTGCTCCTACTGCAGCAAGAGCTTCACCCGGAAGGAGCACCTCGTCAACCACATACGACAACACACGGGCGAGACGCCTTTCAAATGCACATATTGTGCCAAATCGTTTTCTCGAAAGGAACATTTGACGAATCACATAAATCTTCATACGGGAGAGACGCCGCACAAATGTCCCTTCTGCACCAAAACTTTCTCAAGAAAAGAACATTTGACAAACCACGTCAGAATTCATACAGGCGAGTCTCCACATCGTTGTGGATTTTGCCAGAAAACATTTACACGAAAGGAACATCTAACTAACCACATGAAACAACATACTGGCGATACTGCGCATGCGTGTAAAGTTTGTTCTAAACATTTCACCAGAAAAGAACATCTTGTAGCACACATgagATCCCATAGTTGTGGGGAGCGGCCGCACACTTGTGGAGAGTGTGGTAAATCATTCCCTTTGAAAGGAAACCTTTTATTCCACGAACGCTCGCACAATAAGGCTAATGCCAATAACAGGCCATACCGATGTGAAGTTTGTTCCAAGGAATTCATGTGTAAAGGGCACCTGGTGACGCACAGACGAACACACACGGAGCAGGGCGAAGGCGCCACGCCCAGCGCGGAGACTCCGCCCGAGCCTGGCGACTGCTCTGACTGCAACAAGTGTGTCAAAGCAGAGCCTGACCATCCTGACATAAAACACGAAAGCAGgaCTTCTGTTGATGCCAGACCAGATGAAAATAATATGACACAGACTCAACAAAATACTGCAACAGCAGTAATGCAAATATCAAATCAGCAAGTGCGAGTGGGTACGTCGAGCGCGGGCGTGGTGACGGGCGGCGGCGTGGCGACGGGCTCGTTCAGCCACGGCGCGCAGCACCACGCGGCCGCCGGCCTGGCGCACCACCCCGTCACCGTCAACTACTAG
Protein Sequence
MNPEHHSMTTGGGQPPGSSESQNQRIQSAQQQQQNNLPATTSATDLRVNSVNSAVNVALSSVAKYWVFTNLFPGPIPQVSVYGLPAGARIENGKPVQDLGQAHASILNGDPNIILGHHAGQSQVTVSAAGGQQIPVSQIIATQSGQTHEALVAHSHQAELVAAQSNNNNAQVSVTTDQQTHQQVPTNRVEFVQHHNIDMGHHSQQHLMQQQLMATARPEHSNQQIQLTVSEDGIVTVVEPAGSKLVDKEELHEAIKMPGDHGLTVHQLQQLVGQQVIDSVVRIEQATGEPANILVTHNPDGTTSIEAESLIVKDEKNSSKMETAQFAIPTEIKEIKGIDLKNVGTMGMEGAVVKISAGASEHDLHAMYKVNVEDLSQLLAYHEVFGKLNADGQQQAKVITEVEVEPGTSATMSEAESSPGHHSCDICGKIFQFRYQLIVHRRYHGESKPFTCQVCGSAFANPVELSRHGKCHLAGDPNERHAKRMAQDKPYVCTTCHKTFSRKEHLDNHVRSHTGETPYRCEFCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHFMNHVMWHTGETPHHCQICGKKYTRKEHLMNHMRSHTNDTPFRCDLCGKSFTRKEHFTNHILWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCTFCSKSFTRREHLVNHVRQHTGETPFQCGYCPKAFTRKDHLVNHVRQHTGESPHKCSFCTKSFTRKEHLTNHVRQHTGESPHRCTFCAKSFTRKEHLTNHIRQHTGETPHKCTFCPRAFARKEHLNNHIRQHTGVTPHSCSYCSKSFTRKEHLVNHIRQHTGETPFKCTYCAKSFSRKEHLTNHINLHTGETPHKCPFCTKTFSRKEHLTNHVRIHTGESPHRCGFCQKTFTRKEHLTNHMKQHTGDTAHACKVCSKHFTRKEHLVAHMRSHSCGERPHTCGECGKSFPLKGNLLFHERSHNKANANNRPYRCEVCSKEFMCKGHLVTHRRTHTEQGEGATPSAETPPEPGDCSDCNKCVKAEPDHPDIKHESRTSVDARPDENNMTQTQQNTATAVMQISNQQVRVGTSSAGVVTGGGVATGSFSHGAQHHAAAGLAHHPVTVNY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00704247;
90% Identity
iTF_01166931;
80% Identity
-